Mitosis Review • A long stretch of DNA that codes for a protein is a ___________________ • Many of these put together forms a ___________________ • These are all located in the ______________ of the cell • Each human’s normal cells have ___ chromosomes • We call these cells ___________ cells • Each human’s sex cells have ____ chromosomes • We call these cells ___________ cells Alleles • In all of your body cells (also called somatic cells, you have 2 copies of every gene • 1 copy from your father, 1 copy from your mother • The two alleles combined code for traits and characteristics The Cell Cycle • A cell has 2 main stages in its life: 1. Interphase: • 95% of the cell’s life is spent in this phase • Not dividing 2. Mitosis: • The cell divides into 2 identical daughter cells • Split into 4 stages DNA Replication • Remember: a normal body cell needs to have 46 chromosomes • This means before mitosis can happen, the mother cell has to replicate (make a copy) its DNA • DNA replicates in S phase (a part of interphase) Mitosis • Has 4 stages: • • • • Prophase Metaphase Anaphase Telophase Stage 1: Prophase • Nuclear membrane disappears • Before mitosis happens, DNA is defused throughout the nucleus – During prophase, DNA coil up into chromosomes and take shape • Organelles called centrioles start to exude spindle fibres 8 Stage 2: Metaphase • The duplicated chromosomes align along the equator of the cell • The spindle fibres attach to the centromeres of each chromosome pair 9 Stage 3: Anaphase • Spindle fibres pull the chromosomes pairs apart towards the two poles of the cell 10 Stage 4: Telophase • Chromosomes start to uncoil and decondense • Cleavage furrow forms near the middle of the cell • One cell splits into two through cytokinesis 11 Identify the stages! 12