Cells Have Cycles Too! (3) So we all know that organisms grow – they increase in the amount of cells that they have. But where do all those cells come from? They don’t really reproduce the same way that humans or animals do – cells use a process called mitosis to divide into 2 new cells. They then keep dividing over and over again and now you have a multicellular organism! But there are a lot of things that need to happen before mitosis. (5) Each cell has a ‘life cycle’ that it moves through – in cells, this is called the Cell Cycle. There are several stages that cells go through before they can divide. Most of the life of a cell is spent in a stage called interphase. During this stage, 3 important things need to happen in order for the cell to divide. The cell needs to grow – it uses up energy and gets bigger in size (this is called the G1 stage – growth 1). Then, the chromosomes made of DNA inside the cell’s nucleus make copies of themselves – meaning, there are now 2 copies of the DNA inside the nucleus! After the chromosomes duplicate, the cell spends the rest of interphase growing (this is called the G2 phase) and getting ready to divide into 2 new cells. (4) Once a cell is ready to divide, it enters a phase called prophase, which is the first stage of mitosis. In prophase, the membrane around the nucleus fades away and the DNA scrunches into short pairs called chromatids, which you can see clearly under a microscope. These chromatids are linked together by a centromere, which acts sort of like a rubber band holding them together. (3) In metaphase, the second phase of mitosis, the chromatids line up along the middle of the cell, which is called the equator (just like the Earth!). They line up in the middle, which is a good way to remember what happens in metaphase. Metaphase = middle. (3) In anaphase, the third phase of mitosis, the chromatids are pulled apart by threads called the spindle fiber. A side of each chromatid is pulled to either end of the cell so that each new cell gets a full set of DNA. The cell also starts to look longer as well, as if it is being pulled apart. This is a good way to remember anaphase – the DNA is pulled apart and the cell starts to pull apart. Anaphase = apart. (4) In telophase, the fourth phase of mitosis, the DNA starts to shrink back into a small ball, which is going to become the new nucleus of each cell. The spindle fiber starts to disappear and now you should be able to see a small dent forming down the middle of the long cell. Mitosis is almost over! (3) The last phase is called Cytokinesis. Cytokinesis starts with the same 4 letters as cytoplasm….and that’s what cytokinesis is – the division of the cytoplasm. The cell pinches off into 2 new, smaller cells that each get an equal amount of cytoplasm. Bam! 2 new cells – small ones - but they have all of their interphase stage to grow and get ready to divide again. Total Questions: 25 Total Pictures: 7 Total Points: 32