SMART The Virus What they are and how they work What is a virus Viruses are particles of nucleic acids, proteins, and in some cases, lipids. Are parasites *Virus is the Latin word for poison *Are they alive? Living things: – Are made up of cells NO NO/YES – Reproduce – Based on a universal genetic code YES – Grow and develop No – Obtain and use materials and energy NO – Respond to their environment NO – Maintain stable internal environment NO – Change over time YES Viral Structure Basic Structure: – DNA or RNA core – Protein coat = capsid Sketch this T4 Bacteriophage Other structures Tobacco Mosaic Virus Lytic Infection Lytic Infection: Virus enters a cell, makes copies of itself, and causes the cell to burst *Lyse = burst Lysogenic Infection Lysogenic Infection: A virus integrates its DNA into the DNA of the host cell, and the viral genetic information replicates along with the cell’s DNA Ex: Herpes simplex Lytic vs. Lysogenic Retroviruses “retro-” means backwards Retroviruses use RNA – Produce DNA copy in cell of their RNA – DNA is inserted into host DNA – Can remain dormant Ex: HIV/AIDS Retrovirus = Hard to fight Bacteriophage Bacteriophage is a virus which attacks a bacteria! * “phage” = Greek = eating I am sick with a virus can I have some antibiotics? *NO!!!! Antibiotic means against life . . . Viruses aren’t living!!!! We can vaccinate beforehand, but once you are sick with a virus, Dr.’s can only give you stuff for symptoms.