Week #8 (9/8-9/12) Warm Up – Mon, 9/8: - None Anatomy Fun Fact: Have out: Nothing Pick up: Nothing The hardest bone in the human body is the jawbone. Homework: 1. Agenda: 1. Patch Adams movie 2. Guest Speaker Thank You – Fri, 9/12 Osseous Tissue Quiz #1 – Tues, 9/16 Histology of the Skeletal System: Osseous Tissue Learning Goal: Students can describe the basic histology of the Skeletal System. Students will be able to: Describe the 5 major functions of bone Identify the 6 classifications of bones Explain the functions & relationships of osteocytes, osteoblasts, osteoprogenitor cells & osteoclasts Describe the important effects of hormones & nutrition on bone health Osseous Tissue Latin Roots • • • • • • • • • • Oss/osteo- = bone Hema(o)- = blood -poie = to make Coxa = hip Carp- = relating to the wrist Tars- = ankle Dia- = apart, through Epi- = on top of Peri- = around Endo- = within, inside • • • • • • Phys- = nature, movement Dipl- = twofold, double Pro- = for, forward Gen- = birth -cyte = cell -blast = cell with a nucleus, embryo • -clast = broken • -oid = like, similar to Why is Bone considered an Organ? • Bones are organs (organ level of organization) because they contain different types of tissue – – – – Osseous Nervous Blood Cartilage Functions of Bones • Support – hard framework that supports body & cradles soft organs • Protection – fused bones of skull, vertebrae, rib cage • Movement – skeletal muscles use bones as levers • Mineral Storage – calcium & phosphate • Blood Cell Formation (hematopoiesis) – RBC & WBC forms within red marrow cavities of certain bones Week #8 (9/8-9/12) Warm Up – Tues, 9/9: - Show US your Osseous Tissue Index Cards!!! Anatomy Fun Fact: The hardest bone in the human body is the jawbone. Have out: Osseous Tissue Index Cards Bone diagram Osseous Tissue PPT notes Pick up: Skeletal Sys. Outline Homework: 1. Agenda: 1. Osseous Tissue lecture – Classification, Anatomy & Bone Histology 2. Bones recap 2. Guest Speaker Thank You – Fri, 9/12 Osseous Tissue Quiz #1 – Tues, 9/16 Classification of Bones • Classified according to shape: – Long Bones – has a shaft & 2 ends; made mostly of compact bone but may contain spongy bone in its interior • Ex. Femur, tibia, fibula, humerus, fingers of hand – Short Bones – cube-like & contain mostly spongy bone; compact bone provides thin surface layer • Ex. Bones of carpus (wrist) & tarsus (ankle) • Sesamoid Bones – small, flat, shaped like sesame seed; develop in tendons located near joints – Ex. Knee cap (patella) Classification of Bones • Classified according to shape: – Flat Bones – thin, flattened & usually a bit curved; have 2 relatively parallel compact bone surfaces • Ex. Sternum, ribs, skull • Sutural Bones – small, flat, irregular shaped bones of skull – Irregular Bones – bones that do not fit above classification • Ex. Vertebrae & os coxa (pelvis) Long Short Flat Irregular Anatomy of Long Bones • Diaphysis (shaft) – composed of a thick collar of compact bone that surrounds a central medullary cavity (marrow cavity) • “dia” – passing through • Epiphyses – bone ends • “epi” – on top of • Exterior made up of compact bone • Interior is spongy bone • Why are the exterior & interior regions of the epiphyses structured this way? • Joint surface of each epiphysis is covered with thin layer of articular cartilage (cushion) Anatomy of Long Bones • Periosteum – outer surface of diaphysis • Richly supplied with nerve fibers & blood vessels • Endosteum – a delicate covering of internal bone structures • Why are there 2 wrappings found within long bone structure? Anatomy of Short, Irregular & Flat Bones • Thin plates of periosteum-covered compact bone on outside • Endosteum-covered spongy bone (called diploe in flat bones) on inside Anatomy of Bones • All bones contain external compact bone & internal spongy bone filled with red or yellow bone marrow Hematopoetic Tissue in Bones • Hematopoeisis: formation of blood cells • “hema” – blood • “poiesis” – production or formation of • Infants • Medullary cavity & all spongy bone contain red marrow • Adults • Diaphysis is usually filled with fatty (adipose) yellow marrow • Majority of hematopoiesis in long bones occurs in head of the femur & humerus • Most important blood production occurs in diploe of flat bones (sternum) & in some irregular bones (hip bone) Week #7 (9/4) Warm Up – Friday 9/4: Have out: Anatomy Fun Fact: Pick up: - Osseous Cells Relationships Review Humans & giraffes have the same number of bones (8) in their necks. Giraffe neck vertebrae are just much, much longer! Osseous Cells diagram Osseous Latin index cards Skeletal Sys. Pre-Test Osseous Tissue PPT notes Pt 2 Homework: 1. Agenda: 1. Osseous Tissue lecture – Bone Growth/ Cartilage, Effects of Nutrition & Hormones on Bone & Bone Fractures/Repair Osseous Tissue Quiz #1 on Wednesday 9/9 1 (use anatomical direction term) 5 (space) 2 6 (stuff) 7 (covering) 8 (covering) 3 (use anatomical direction term) 4 What classification would this bone fall under? Name the identified regions or coverings of a long bone. Name a function of bone. What is formed in the medullary cavity of a long bone? Bone Histology Now what level of organization are we talking about? • Bone contains specialized cells & a solid, sturdy matrix (calcium salts deposited around collagen protein fibers) • Osteocytes: mature bone cells that occupy a lacuna (osseous cell “bed”) • “osteo” – bone • “cyte” - cell Bone Histology • Bone cells are arranged in cylindrical patterns throughout bone around thin tubes called Haversian canals that contain nerves & blood vessels that nourish the osteocytes. • Tiny cytoplasmic extensions called canaliculi (little canals) connect the osteocytes to one another & the Haversian canals. Osseous Cells relationships (~4:13) Functions of Osteocytes • Maintain the protein & mineral content of the matrix • Secrete chemicals that dissolve old matrix & then stimulate the depositing of calcium crystals • Assist in the repair of damaged bone • If released from lacunae, osteocytes can become an osteoblast or an osteoprogenitor cell Osteoprogenitor Cells • Stem cells that undergo mitosis, producing daughter cells that differentiate into osteoblasts • Aid in repair of bone fractures • Located in the periosteum