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DEPARTMENT OF GENERAL MICROBIOLOGY
SECTION OF MORPHOLOGY OF MICROORGANISMS AND ELECTRON MICROSCOPY
SECTION OF MICROBIAL GENETICS
SECTION OF MICROBIAL BIOCHEMISTRY
DEPARTMENT OF APPLIED MICROBIOLOGY
LABORATORY OF MICROBIAL BIOSYNTHESIS AND ECOLOGY
LABORATORY OF EXTREMOPHILIC BACTERIA
LABORATORY OF APPLIED BIOTECHNOLOGIES
RESEARCH GROUP “MATHEMATICAL MODELLING AND COMPUTER METHODS”
DEPARTMENT OF INFECTIOUS MICROBIOLOGY
LABORATORY OF ZOONOSIS AND BACTERIAL VIRULENCE
LABORATORY OF GENETICS AND DRUG RESISTANCE OF MYCOBACTERIA
LABORATORY OF ANTIMICROBIAL AGENTS
DEPARTMENT OF VIROLOGY
LABORATORY OF EXPERIMENTAL CHEMOTHERAPY OF ENTEROVIRAL INFECTIONS
LABORATORY OF EXPERIMENTAL CHEMOTHERAPY OF INFLUENZA
LABORATORY OF ONCOLIYTIC VIRUSES
LABORATORY OF VIRAL PROTEINS
DEPARTMENT OF IMMUNOLOGY
LABORATORY OF IMMUNOMODULATORS
LABORATORY OF IMMUNOPATHOLOGY AND EXPERIMENTAL IMMUNOTHERAPY
LABORATORY OF NONSPECIFICAL RESISTANCE
SECTION OF MYCOLOGY
ATELIER PASTEUR
About us
HISTORY
The Institute of Microbiology was founded on March 7, 1947 as
an institute of the Bulgarian Academy of Sciences (BAS) by the
world-famous Bulgarian scientist Professor Stephan Angeloff,
Member of BAS, who had been its first director for 15 years.
Acad. Stephan Angeloff
The foundation of the Institute of Microbiology realized the
necessity for a formation of a research center with national
importance, which to carry out contemporary investigations in
rapidly developing and prosperous branches of microbiological
science. The initial period in the development of the Institute
(1947 - 1962) was connected with the studies of the actual after
the Second World War infectious pathology of domestic animals
and humans. The achievements in the study of the etiology and
the development of diagnostic methods and immunoprophylactic
preparations for different infections were significant.
Investigations in the field of infectious immunology was set by
Prof. Vladimir Markov, Member of BAS.
Industrial microbiology started with the
studies of Prof. Ignat Emanuilov, Member of
BAS, on the microbiology of milk and dairy
products, biochemistry and physiology of
lactic acid bacteria and the application of
bacterial
enzymes
(proteinases)
in
cheesemaking. Along with bacteria as
producers of biologically active substances
filamentous fungi were investigated.
In the field of microbial morphology since 1964
electron microscope studies of bacteria,
filamentous fungi, yeasts and cells of the immune
system of the macroorganism were performed.
The investigations in the field of microbial
biochemistry after 1973 aimed the elucidation at
modern biochemical level of the main
peculiarities in the physiology and biosynthetic
capabilities of the microbial cells: various
enzymes, proteinase and nuclease inhibitors,
microbiological transformation of steroids,
protein-lipid interactions in bacterial membrane.
Systemic investigations carried out by Prof.
Simeon Galabov and his collaborators on the
relationship between antigenic structure and
biological properties of bacterial endotoxins
resulting in development of diagnostic kits and
vaccines, as well as data on interferon-inducing
activity. The research work in the field of
microbial genetics was connected with the
problem of prophage interference, genetic
transfer in Bacillus thuringiensis and Streptococci
from group A, hybridization of Actinomyces sp. in
order to increase their productivity, construction
of gene maps of Streptomycetes - producers of
antibiotics,
molecular
identification
of
microorganisms by the use of PCR, as well as
genomic
differentiation
by
M13
DNA
fingerprinting and ribotyping. The Institute of
Microbiology has always played a leading role in
applied microbiology. Microbial producers of a
wide spectrum of biologically active substances
were isolated: enzymes, aminoacids proteins,
carotinoids, and various antibiotics with different
spectrum of activity were isolated. Physiology
and biochemistry of microbial producers,
including extremophilic bacteria as well as the
properties of the synthesized products were
studied. A wide spectrum of methods for
immobilization of enzymes and microbial cells,
producers of biologically active substances, were
elaborated. The investigations in infectious
bacteriology after 1962 were pointed on the
changes provoked in the pathogen during the
course of infectious and immunizatory process.
Later, studies were focused on the factors and
mechanisms of bacterial virulence and bacteriahost interactions. At the beginning of 60th years
started investigations in the field of the
experimental chemotherapy of viral infections.
Systemic studies on the creation and
characterization of some new effective antivirals,
on the combined effects of viral inhibitors and
their mechanisms of action. Iinvestigations on cell
immunity and L-forms of bacteria and a widespectrum immunopharmacological screening was
performed aiming the selection of new active
substances.
MISSION
The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences (BAS) is
national research center in microbiological sciences. It is one of the leading institutes in the field
of microbiology for South-Eastern Europe. By its wide research area the Institute is unique
among the other institutes from the Pasteur family. The institute is recognized in Europe and
worldwide for its modern research tendencies. Ever since its foundation 60 years ago, the
Institute’s strategic lines have been: (1) investigations on problems implicated in public health
and biotechnology; (2) teaching activities and training of PhD students. In 2004 the Institute of
microbiology was associated with Institut Pasteur, Paris and a member of the International
Network of Pasteur Institutes (INPI). This is a great recognition of the activities of our institute
by this world centre of microbiology and molecular biology, a leader in the struggle against
infectious diseases.
THE STEPHAN ANGELOFF INSTITUTE OF MICROBIOLOGY NOWADAYS
The Institute comprises 11 departments and a staff of 171 including 6 professors, one of them
Corresponding Member of BAS, 34 associate professors and 52 research scientists. The expertise areas
are: morphology and ultrastructure, genetics, biochemistry, physiology and ecology of microorganisms,
mycology, virology, infectious microbiology and immunology. The efforts are currently concentrated on
some key practical problems of public health, drug design, food safety, biotechnology, and
environmental protection.
Research scientists
Corresponding member of BAS – 1
Professors – 4
Research Scientists - 53
Scientific degree holders:
Age to 35 – (24,2%)
Research Assistants with MD, DVM,
MS, PhD high university degree - 45
Doctor of sciences, DSc -7
Research Assistants, PhD – 2
Promotion of the research scientists during 1999 - 2007
Title
Promotion
1999 2000 2001 2002 2003 2004 2005 2006 2007
Corresponding
1
member
Professors
1
1
Assoc. Professors
2
1
Research
3
6
2
1
14
1
4
16
4
8
scientists
BUDGET FOR 2007
Income
Government subsidy
1
Levs (BGN)*
1 427 000. 00
4
10
Foreign currencies projects
176 778. 00
Projects, supported by Ministry of Education and
Science and the Innovation fund of Ministry of
507 850. 00
Economics
Other projects
46 700. 00
Rent, prizes etc.
30 968. 00
Total incomes:
2 189 296. 00
FIELDS OF SCIENTIFIC RESEARCH RELATED TO PUBLIC HEALTH
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Experimental chemotherapy of emerging
and re-emerging viral infections
(influenza, enteroviral, flaviviral and
others)
Pathogenesis of some infectious diseases
and additives in complex therapy
Oncogenic and oncolytic viruses
Balkan Endemic Nephropathy
Virucidal agents
Tuberculosis – molecular characterization
of drug-resistant strains of
Mycobacterium tuberculosis
Bacterial zoonosis
Bacterial virulence
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New antiviral and antimicrobial agents
New approaches for bacteriological
monitoring of food products
Vaginal lactobacilli
Resistance to antiviral and antimicrobial
agents
Mechanisms of autoimmune diseases
New vaccines technologies
Microbial biosynthesis of steroids and
other biochemicals
Galantanamin (nivalin) production
technology
MAIN RESEARCH TOPICS IN APPLIED MICROBIOLOGY AND MICROBIAL ECOLOGY
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Molecular taxonomy of microorganisms
Molecular genetic of microorganisms of
biotechnological and medical significance
Ultrastructure of saprophytic and
pathogenic microorganisms
Regulatory mechanisms of microbial
metabolism
Cell response against different type of
physiological stresses and mechanisms of
adaptation of bacteria and fungi

Biological activity and potential of
lactic acid bacteria as bioprotective
starters for dairy products and their
probiotic properties for human health.

Microbial surfactants (biosurfactants) –
biosynthesis, isolation, mechanism of
action and application
Novel microbial antibiotics
Microbial biosynthesis of biological-active
compounds: enzymes, amino acids,
growth factors etc.
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Microbial transformation of steroid
compounds
Ecological biotechnologies
Purification of water and soil from
heavy metal
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Production of biogas
Biosynthesis
of
biological
active
compounds by plant suspension cultures
Biodiversity,
ecology
and
biotechnological
potential
of
extremophilic microorganisms
Microbial degradation of aromatic
compounds
RESEARCH PROJECTS
The research work of the Institute is funded on project principle.
Program
European commission
4 Framework Program
5 Framework Program
6 Framework Program
Number
6
1
3
Program Leonardo da Vinci
NATO
UNESCO
Program ACIP of IPPI
Institutes from the network of Pasteur’s Institutes
German center of cancer research
4
13
1
2
1
2
Foundations in Germany
Ministry of education, science and culture, Austria
Ministry of science and culture, Белгия
3
4
1
Total number
39
Research projects 1997 – 2007:
PROJECTS DURING THE LAST FOUR YEARS
Years
Projects,
financed by
Ministry of
education and
science
Ministries and
institutions in
Bulgaria
2004
2005
2006
2007
42
50
53
61
4
3
6
4
ЕС NATO Programs between Companies in Total International
UNESCO etc.
academics and
Bulgaria and number of projects
institutes
abroad
projects
10
11
13
15
17
12
15
14
13
6
8
5
86
82
95
99
There is a stable tendency of raising the number of projects.Current research projects are supported by
foreign and Bulgarian grants: a total of 35 projects by foreign institutions (2 by FP6 of the EC, 9 by NATO
grants, 1 by UNESCO, 3 by ACIP program of INPI, 1 by the French governmental foundation, 1 by the
Swiss governmental foundation, 2 by Deutsches Krebsforschung Zentrum and 6 by research and
development centers of foreign companies), and 40 - by the National Science Research Fund at the
Ministry of Education and Science, Bulgaria.
INTERNATIONAL COOPERATION
The Institute’s activities are widely based on
international cooperation, with projects between
two or more institutions. We are searching for
new projects as part of the international research
programs. Scientists from the Institute are
respected partners for different scientific
organizations abroad, companies, institutes and
laboratories. During 2007 the Institute has been
involved in 40 international projects and joint
studies, 15 of which were financed through EC,
NATO, UNESCO and other programs, 18 of them
were developed within the frames of academic
and institute cooperation, and 7 were financed
from companies abroad.
35
29
33
33
New scientific bridges have been created
between the IMSA and the Saint-Petersburg
Institute Pasteur and Institute Pasteur of
Guadeloupe (drug-resistant Mycobacterium
tuberculosis), Institute Pasteur Paris (human
papillomaviruses, genetics of primary HBV/HCVinduced liver carcinoma), German Center of
Cancer Research (DKFZ, Heidelberg) (oncolytic
viruses), University of Leipzig and the Technical
University of Dresden (plant cell cultures and
biotechnologies), University of Viterbo and
University of Pavia (new enzymes of Antarctic
microorganisms), University of Strathclyde,
Glasgow
(biotechnologies
of
eukaryotic
microorganisms), University of Naples (enzymes
from thermopile bacteria) and Institute of
Agricultural Sciences and Fishery, Ghent (control
on food products), etc.
Some of the dissertation works are part of
the international partnership, which finalize as
dissertation theses supervised by scientists from
the Institute of microbiology and from RIIP, CNRS
(France) and others.
During 2007 the scientists from our institute
took part in 79 scientific forums abroad, 25
foreign scientists have visited the institute; 7
specializations and workshops were taken from
students from our institute abroad. Researchers
from our institute had 22 business trips related to
organization and scientific work and lecturing.
Our young colleagues specialized in foreign
institutes in Germany, France, Spain and others.
JOINT ACADEMIC PROJECTS AND PROJECTS BETWEEN INSTITUTES
1997 – 2007
France
Germany
Russia
R. Macedonia
Slovakia
4
USA
Italy
Ukrain
Latvia
Taiwan
Check R.
Hungury
2
1
2
1
2
1
1
2
1
8
5
TOTAL NUMBER 28
INNOVATIONS AND BUSINESS RELATIONS
The IMicB has opened an Innovations
office, which provides information, ideas, and
workshops for the proper use of EC funds, help to
prepare applications in EC program’s calls, etc.
There are materials available for everybody who
has interest.
The institute of microbiology has
participated to the International fair in Plovdiv on
the advertising table of BAS, where we have
presented achievements in the area of microbial
biotechnology. A new catalog came out to the
interested in this area about the created novel
technologies of extracting biologically active
substances and possibilities for expertise
(supplementary 1).
National innovation fund is financing
development of technologies, associated with
national mile stones and related to the
production of energy from biogases, new
biomaterial products with application in farming,
immunostimulation reagent for treatment of
tumors on animals and diagnostic and
therapeutic bioproducts.
The group of innovation achievements
includes also the ones financed by Ministry of
education, science and culture on the national
scientific programs Genomic, New technologies in
the power supply and Nanotechnologies. Main
priority of these programs is achieving new
knowledge and creation of modern technologies
in important areas.
As an associated member of Institute
Pasteur, IM participates in modern research of 4
different areas, which is one of the most
important health problems of our time –
tuberculosis, papiloma and hepatit viruses –
factors, which provokes cancers and infectious
arthritis.
PROJECTS WITH COMPANIES FROM BULGARIA AND ABROAD
Projects with companies from Bulgaria and abroad
Number
Germany
12
France
3
Holland
1
Denmark
3
Switzerland
1
Japan
1
Turkey
1
UAR
1
Total number 23
Joint projects with Bulgarian companies
Total number 25
projects financed by the ministry of education, science and culture
universities and other institutions
Average per year
60
There are also projects, financed by
Ministry of education, science and culture ЕС,
NATO and the partnership associated with the
innovation problems – isolation of new
producents of biologically active substances of
extreme territories, isolation and characterization
of probiotic products, new technologies for
obtaining energy and electrical power from
organic matter, obtaining new drugs to treat
sepsis based on biological weapons; new
methods and strategies in the treatment of
bacterial and virus diseases, biodegradation of
toxic pollutions, isolation and use of
biosurfactants, etc. Projects related to the
production of Bulgarian yogurt deserve special
attention, which is due to the achievements of
the IM to obtain patent certificate.
The IMicB is also a partner in
agricultural work, which has been ordered in
cooperation with foreign companies and such
ones from Bulgaria. There are many examples
where our institute is a solo scientific
organization, which works on problems
created directly from thing the effect of
imodin in experimental infection with flue
virus, estimation of the protection effect of
substances
against
pseodotuberculosis,
microbiological analysis of chemical predrugs
and final drug products and its trade packages.
RESEARCH ACHIEVEMENTS
Infectious Microbiology
 Characterization of bacterial-host interactions
(invasion, persistence, intracellular survival, as
well as the bioenergetic mechanisms ensuring
these processes) at experimental melioidosis,
lysteriosis, yersiniosis and salmonelosis.
 Application of Yersinia outer membrane
proteins in improved ELISA and immunoblot
tests for diagnosis of yersiniosis in humans, pigs
and rabbits.
 Development of new generation of live carrier
vaccines by using genetically constructed
mutants of Yersinia enterocolitica and Yersinia
pseudotuberculosis.
 lucidation the role of Yersinia LPS antigen in
induction of reactive arthritis in experimental
models.
 Molecular epidemiological analysis (population
structure included) of the incidence and
transmission
of
multidrug-resistant
Mycobacterium tuberculosis strains in Bulgaria
by using a complex of molecular bioiological
methods and population structure analysis. The
multidrug resistant and hypervirulent Beijin
strain was not found in Bulgaria. The results
contributed to the control the global spread of
multidrug tuberculosis worldwide.
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 The photoinhibitory effect applicable in the
practice for photosterilization of contaminated
with enterobacteria water ecosystems.
 Optimization and application of PCR-DGGE for
direct detection and typing of Campylobacter
jejuni and Campylobacter coli in caecal samples
of broilers without preliminary enrichment.
This method allows reliable and fast detection
and
identification
of
pathogenic
Campylobacters infections in humans.
 Development of a lectin-based approach for
differential labeling of Escherichia coli
exopolysaccharide, O and K antigens and its
application for complex characterization of
antigen variations by microagglutination, ELLA,
ligand blotting, immunoelectrophoresis and
lectin-gold.
 The Pomorie mud as an inductor of enzyme
neuraminidase secretion at pathogenic genera
Vibrio and Aeromonas.
 Original newly isolated lactobacillus strains with
biological activity and potential to both
preserve the healthy homeostasis of the
vagina, and as gastrointestinal probiotics.
 Characterization of uridine-monophosphate
kinases of Streptococcus pneumoniae and
Escherichia coli as potential targets for
development of specific antibacterial agents.
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Virology
 Discovery of new original antiviral substances
effective in the treatment of viral infections in
humans:
- Guanidine derivative - chemotherapeutic
agent, inhibiting replication of adenoviruses,
effective in the treatment of epidemic
keratoconjunctivitis and other adenovirus

conjunctivitides (widely spread viral infections
of the eye). It is the first known antiadenoviral
chemotherapeutic agent.
- Dipyridamole - a large spectrum antiviral
agent, acting via induction of endogene
interferon, used for prevention of flu and other
acute viral respiratory infections.
Clearing-up of the mode of antiviral action of
mopyridone on influenza A virus replication
(binding to the structural M1 protein).
Discovery and characterization of the antiviral
effect of cycluridine towards flavivirus
infections, the first chemotherapeutic agent
efficacious in the mucosal disease-virus
diarrhoea in cattle.
Establishment of synergistic combination effect
of rimantadine and oseltamivir against
influenza virus A (H3N2) experimental
infection.
Clearing-up of the drug-resistance
phenomenon in enterovirus replication
inhibitors interacting with the viral capsid
protein VP1 – problems of the development of
highly effective anti-enteroviral chemotherapy.
Phenotype and molecular genetic
characteristics of disoxaril resistant and
dependent mutants of Coxsackie virus B1.
Discovery of a series of highly efficient
synergistic combinations of enteroviral
replication inhibitors – a perspective approach
for dissolving the drug-resistance problem.
Discovery of oxoglaucine: a highly effective and
large-spectrum inhibitor of enterovirus
replication.
Establishment of the anti-influenza virus effects
of novel protease inhibitors from
Streptomyces.
Determination of the role of the oxidative
stress in the pathogenesis of flu and the
influence of certain antioxidants of natural and
synthetic origin and antivirals on this process.
Determination of the antiviral spectrum of the
highly effective and broad-spectrum virocidal
composition of new type (Manorapid
Synergy®), implemented in the clinical practice
as hand disinfectant.
Characterization of the immune state and the
role of hantavirus infections in
etiopathogenesis of the Balkan endemic
nephropathy.
 Describing
of
the
phenomenon
of
inflammation-induced enhancement of IgG
antigen binding polyreactivity.
 Development of DNA vaccines with a new type
of build-in adjuvanticity.
General and Applied Microbiology

 Molecular epidemiological study of the role of
human papillomaviruses in etiology of CIN and
cervical cancer in Bulgarian population.
 Establishment and characterization of the
cancerolytic effect of some parvoviruses.
Immunology
 Establishment of the ability of the opportunistic
yeast Candida albicans to induce reactive
arthritis in normal and in predisposed
individuals. Analysis of the relationship
between infections and rheumatic diseases
contributed to the development of new
therapeutic approaches.
 Establishment and characterization of the
immunomodulatory properties of coumarin, 7hydroxycoumarin, yeast superoxide dismutase
and molluscan hemocyanins. They have
therapeutic potential as antitumor agents as
well as for the prophylaxis of infectious
diseases.
 Discovery of previously unknown mechanisms
of the immunomodulatory activity of pooled
IgG (IVIg) in autoimmune patients.
 Development of experimental improved “nextgeneration” pooled human immunoglobulin
preparation with an improved therapeutic
effect in systemic inflammatory diseases.
 Describing of the immunomodulatory potential
of normal pooled human IgM in autoimmune
and inflammatory diseases.
 Development of a novel approach for silencing
selectively autoreactive disease-associated B
cells in autoimmune diseases.
Original evidence about the fine structural
changes of model Gram-positive and Gramnegative bacteria under the action of
rhamnolipid-biosurfactant with surfaceactive properties.
 Ultrastructural peculiarities, the growth and
reproductive capacity of producers of
thermostable exo-inulinase and cyclodextrin
glucanotransferase immobilized on different
matrices.
 Ultracytochemical localization of acid
phosphatase in nongerminating and
germinating conidia of the fungus Humicola
lutea.
 Development of a simple and rapid test for
differentiation of aerobic from anaerobic
bacteria applicable for determination of the
respiratory type of pure cultures isolated from
different areas of the environment.
 New evidence for the relationship between
oxidative stress and various environmental
challenges (heavy metals, heat- or cold-shock,
cell immobilization).
 Evidence for unusual existence of Cu/Zn-SOD in
mitochondrial intermembrane space
 Microbial transformation of the steroid
compounds sitosterol and androstenedione
was performed by resting cells of
Mycobacterium sp. and Rhodococcus sp.,
respectively, in a single phase organic solvent
based medium.
 Isolation and characterized of biosurfactants of
microbial origin applicable in biomedicine,
bioremediation and biotechnology.
 Identification of catabolic genes, coding
enzymes with phenol-hydroxilase activity at the
original yeast strain Trichosporon cutaneum
R57 possessing high activity in degrading
aromatic and aliphatic compounds
 Original approaches to the moleculartaxonomic characterization of lactic acid
producing bacteria and the rapid monitoring of
Lactobacilli from different ecological niches.
 The genetic, physiological and other factors,
controlling the sexual process of the yeast
Hansenula polymorpha.
 A method for production of extra cellular αgalactosidase by submerged cultivation of
Aspergillus niger M47 , Penicillium chrisogenum
LN33 and Humicula lutea 1205 on the medium,
composed by wastes from food industry.
 Technologies” for production of L-lysine and Lvaline.
 Preparation of starters for fermented milks
with health benefits by the bacteriocin
producers Lactobacillus bulgaricus BB18 and
Lactobacillus lactis BCM5 and their compatible
strains Streptomyces thermophilus 11A and
Lactobacillus bulgaricus LX1
 Genetic identification of Streptomyces iakurus
DSM 41873., producer of antibiotic complex,
composed of 5 chemically characterized new
components.
 Characterization of phytase isolated from
Antarctic yeats.
 Technology for galanthamine production by
Leucojum aestivum shoot culture
 Determination of genome size of Beta vulgaris
cells by flow cytometry.
 Development of immobilized system for
removal of Cu (II), Co (II) and Fe (III) ions from
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ternary mixed aqueous solutions using fungal
biomass entrapped in hydrophilic organic
polymer.
Development of high effective technology for
biosynthesis of naturally glycosylated Cu/ZnSOD by the fungal strain Humicola lutea 103.
The novel enzyme demonstrated protective
effect against Graffi tumor and influenza virus
infection, as well as improves fertility of ram
and bull spermatozoa during liquid storage and
cryoconservation.
Isolation from Bulgarian hot springs and
characterization of novel bacterial species
(Anoxybacillus
rupiensis,
Anoxybacillus
bogrovensis)
possessing
significant
biotechnological potential.
Isolation of thermophilic Bacillus strains with
potential for application in chemical synthesis
or various detoxification processes, used as
biocatalyst in the synthesis of cyclodextrin
glucanotransferase
and
producers
of
thermostable gellan lyase.
Optimisation and control algorithms and
laboratory biogas technologies for the
anaerobic digestion of organic wastes (specific
and in mixtures), accompanied by biogas yield.
EDUCATIONAL ACTIVITIES
The educational activities of the Institute
include: PhD tuition (35 PhD students within
the last five years); training courses for young
scientists from the Balkan countries at the
Atelier Pasteur on modern methods in
microbiology with lecturers from INPI;
participation in the Leonardo da Vinchi
Programme of EC. Thirteen scientists from
the Institute give lectures at nine Bulgarian
universities.
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Medical university
Faculty of biology, University of Sofia “St.
Kliment Ohridski”
Faculty of Veterinary Medicine, University of
Forestry
Technical University of Sofia
New Bulgarian University
Technical University – Gabrovo
University “Asen Zlatarov” – Burgas
University of Food Technology – Ploviv
Scientists from the institute are involved in
academic activities at:
During 2007, a total of 22 PhD and 12 MS theses are prepared at the Institute;
Form of education
Number of
Students
Graduated PhD
REGULAR
10
1
EXTRAMURAL
1
--
8
2
STUDIES
INDIPENDENT
TOTAL
MS theses’s prepared during 2007 on request
from:
Number of PhD
19
 Faculty of biology, University of Sofia
“St. Kliment Ohridski” -10
 Faculty of chemistry, University of Sofia
“St. Kliment Ohridski” – 2
 Technical University of Sofia – 3
3
EXPERT ACTIVITIES
Scientists from the Institute participate in
scientific councils of academic and other
research institutions, editorial boards of
international and national scientific journals,
in the boards of international and Bulgarian
scientific societies, members of advisory
board of WHO. IMicB was the initiator of the
establishment of the Balkan Society for
Microbiology, and is the head quarter of this
society and the Bulgarian Society for
Microbiology. Consultancy is provided for
many institutions (governmental, university,
private etc) about public health, agriculture,
food industry, ecology and environment.
Scientists are included in the work of many
expert groups among which Expert Council
for Biological Defence at the governmental
Committee for Prevention of the Population
from Natural Disasters and Catastrophes,
Expert Council for Epidemiological Control
of
Infectious
Diseases
and
Immunoprophylaxis,
Commission
for
Eradication of Polyomyelitis at the Ministry
of Public Health, Expert Group on Countering
the Effects of Biological and Chemical
Terrorism at EC, National Agencies of
Standardization and Authorization, etc.
PUBLISHING ACTIVITIES:
Short synoptical collection (Scientific Report) in
English is annually published. Recently is
reestablished the journal of Institute of
Microbiology “Stephan Angeloff” – Acta
Microbiologica Bulgarica. Efforts have been done
for participation to Bulgarian Information
Consortium. The Institute’s library is registered at
the Conference of European National Libraries –
CENL, and joined the National Educational Forum.
Research results are extensively published in
scientific journals, monographs and meeting
proceedings.
http://www.microbio.bas.bg
Staff
Projects
Reports
Contacts
Institute of Microbiology, BAS
Acad. G. Bonchev Str., Bl. 26, Sofia 1113, Bulgaria
Phone: (+359 2) 979 31 57; Fax: (+359 2) 870 01 09; E-mail: micb@microbio.bas.bg