Chapter 4 Tissues Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. • Tissue: a group of similar cells with similar functions • Four basic types of tissues 1. 2. 3. 4. Epithelial Connective Muscle Nerve 4.1 Epithelial Tissues • Five distinguishing characteristics 1. Closely packed cells 2. Attached to connective tissue by a basement membrane 3. Tissue surface opposite the basement membrane is not attached to other tissues 4. Tissue has no blood vessels 5. Tissues regenerate rapidly • Functions vary with location and tissue type – Protection, absorption, filtration, secretion • Glandular epithelium can be found inside glands – Exocrine glands – Endocrine glands 4.2 Connective Tissues • • • • • Most abundant body tissues Support and bind other tissues Never found on exposed surfaces Have the ability to regenerate Consist of few, loosely arranged cells and intercellular substance called matrix • Two broad categories of connective tissues – Connective Tissue Proper • Common tissues that bind other tissues and organs – Connective tissues with specialized functions • Connective Tissue Proper – Functions • Bind together other tissues • Basic supporting framework of organs – Matrix consists of ground substance – Fibroblasts are the most abundant cells – Two types of protein fibers • Collagenous fibers • Elastic fibers – Loose connective tissue, or Areolar • Most abundant in body • Named for its loosely arranged protein fibers • Attaches skin to muscles • Supporting framework for internal organs, nerves, blood vessels • Site for immune reactions – Adipose tissue • Has large numbers of adipocytes that store fat droplets • Common beneath skin and around internal organs • Aids in fat storage and body insulation • Provides a protective cushion – Fibrous connective tissue • Has an abundance of tightly packed collagenous fibers and few cells • Great strength and flexibility • Component of ligaments, tendons, and dermis • Poor blood supply resulting in slow healing – Elastic connective tissue • Has an abundance of elastic fibers • Found where elasticity is needed • Lungs, air passages, arterial walls • Cartilage – Semisolid matrix with embedded chondrocytes living in lacunae – Major functions are support and protection – There are three types of cartilage • Hyaline cartilage • Elastic cartilage • Fibrocartilage • Bone or osseous tissue – Hardest and most rigid due to calcium salts in its matrix, along with collagenous fibers – Provides rigidity and strength to support the body – Matrix is deposited in lamellae around osteonic (Haversian) canals – Osteocytes, located between lamellae, are connected by canaliculi • Blood – Consists of numerous cells in a liquid matrix – Three types of cells • Red blood cells • White blood cells • Platelets – Vital role in transporting material throughout the body 4.3 Muscle Tissues • Cells are unable to divide so regeneration is not possible • Cells are called muscle fibers due to their long, thin appearance • Cells use specialized protein fibers for contraction • Contraction moves the body and produces heat • Skeletal Muscle Tissue – Attached to bones and move the body – Voluntary muscle – Cells are elongated and cylindrical, with many nuclei and striations • Cardiac Muscle Tissue – Found only in walls of heart – Involuntary muscle – Branching muscle fibers that interconnect at intercalated discs – Possess one nucleus and striations • Smooth Muscle Tissue – Occurs in the walls of hollow organs – Involuntary muscle – Cells possess a spindle shape, one nucleus, and not striations 4.4 Nerve Tissue • Found in brain, spinal cord, and nerves • Two main types of cells – Neurons – Neuroglia • Neuroglia are supporting cells that nourish, insulate, and protect neurons • Neurons – The functional units of nerve tissue – Possess a cell body and one or more neuron process – Respond to environmental changes by making neural impulses 4.5 Body Membranes • Thin sheets of tissue • Line cavities, cover surfaces, or separate tissues or organs • Two types of body membranes – Epithelial membranes – Connective tissue membranes • Epithelial Membranes – Composed of epithelial tissue overlying loose connective tissue – Serous membranes • Line ventral body cavity and cover internal organs • Secrete serous fluid to reduce friction • Examples: pleurae, pericardium, peritoneum – Mucous membranes • • • • Line tubes and cavities open to the exterior Possess goblet cells to make mucus Keeps cells moist and lubricated Examples: digestive and respiratory tracts – Cutaneous membrane • Skin • Connective Tissue Membranes – Formed only of connective tissue – Examples: 1. 2. 3. 4. Meninges Perichondrium Periosteum Synovial membrane Tissue Repair • Following minor injuries, tissues repair themselves by regeneration – the division of the remaining intact cells. • The capacity to regenerate varies among different tissues. Tissue Repair – Epithelial tissues, loose connective tissue, and bone readily regenerate. – Cartilage and skeletal muscle have little capacity for regeneration. – Cardiac muscle never regenerates. – Nerve tissue in the brain and spinal cord usually does not regenerate. Tissue Repair • After severe injuries, repair involves fibrosis, the formation of scar tissue. – Formed by an excess production of collagenous fibers by fibroblasts. – A keloid is a mass of scar tissue forming on the skin surface due to excessive connective tissue – Scar tissues that join together tissues or organs abnormally are called adhesions, which sometimes form following abdominal surgery. Tissues and Tumors • Because epithelial and connective tissue cells are active in cell division, they are prone to the formation of tumors when normal control of cell division is lost. • The most common types of cancer arise from epithelial cells – possibly due to increase exposure to carcinogens, cancer-causing agents, in the environment. Tissues and Tumors • A cancer derived from epithelial cells is called a carcinoma. • Malignant tumors that originate in connective tissue are also common types of cancer. A cancer of connective tissue is called a sarcoma.