Table 2. List of Chemicals with Threshold Limit Values1 (TLV) primarily based on
sensory irritation. No RD50 values are available for these chemicals.
This table includes only volatile organic chemicals (VOCs).
#
1
Acetic anhydride
108-24-7
Documentation
Date1
2010
2
Acetophenone
98-86-2
2008
3
4
5
6
7
8
9
10
11
Acrylic acid
Adiponitrile
Allyl bromide
Ally propyl disulfide
Benzotrichloride
Benzoyl chloride
Benzyl acetate
sec-Butanol
iso-Butene
79-10-7
111-69-3
106-95-6
2179-59-1
98-07-7
98-88-4
140-11-4
78-92-2
115-11-7
1986
1990
2011
2001
1994
1992
1990
2001
2007
12
13
14
15
16
17
sec-Butyl acetate
n-Butyl acrylate
n-Butyl mercaptan
o-sec-Butylphenol
Camphor (synthetic)
Carbon tetrabromide
105-46-4
141-32-2
109-79-5
89-72-5
76-22-2
558-13-4
1965
1996
1968
1977
1990
1972
18
Catechol
120-80-9
1985
19
20
21
22
23
24
Chloracetaldehyde
Chloracetone
Chloracetyl chloride
1-Chloro-1-nitropropane
ß-Chloroprene
Cumene
107-20-0
78-95-5
79-04-9
600-25-9
126-99-8
98-82-8
1990
1986
1988
1971
1990
1997
25
26
Cyanogen
Cyanogen bromide
(inorganic ?)
Cyanogen chloride
(inorganic ?)
Cyclohexanol
Cyclohexene
Cyclopentadiene
Cyclopentane
460-19-5
506-68-3
1966
2014
506-77-4
2013
108-93-0
110-83-8
542-92-7
287-92-3
1979
1964
1963
1978
27
28
29
30
31
Chemicals
CAS #
TLV-TWA or
TLV Basis3
STEL2 (ppm)
10
URT & eye irr; pulm
func
10
URT irr; CNS impair,
Pregnancy lost
2
URT irr
2
URT & LRT irr
0.1
Eye & URT irr
0.5
URT & eye irr
0.1
Eye, skin & URT irr
0.5
URT & eye irr
10
URT irr
100
URT irr; CNS impair
250
URT irr; body weight
eff
200
Eye & URT irr
2
Irr
0.5
URT irr
5
URT, eye & skin irr
2
Eye & URT irr; anosmia
0.1
Liver dam; eye, URT &
skin irr.
5
Eye & URT irr;
dermatistis
C1
URT & eye irr
C1
Eye & URT irr
0.05
Eye, URT, & skin irr
2
Eye irr; pulm edema
10
URT & eye irr
50
Eye, skin & URT irr; CNS
impair
10
LRT & eye irr
C 0.3
Eye & resp tract irr;
pulmonary edema
C 0.3
Pulm edema; eye, skin,
& URT irr
50
Eye irr; CNS impair
300
URT & eye irr
75
URT & eye irr
600
URT, eye, & skin; CNS
impair
32
33
34
35
Diacetone alcohol
Diazomethane
2-N-Dibutylaminoethanol
Dichloroacetic acid
123-42-2
334-88-3
102-81-8
79-43-6
1979
1970
1980
2002
50
0.2
0.5
0.5
36
37
1,4-Dichloro-2-butene
1,1-Dichloroethane
764-41-0
75-34-3
1990
1990
0.005
100
38
39
40
41
42
43
44
Dichloroethyl ether
1,1 Dichloro-1-nitroethane
Dicyclopentadiene
Diethylene triamine
N,N-Diethylhydroxylamine
Diethyl ketone
Difluorodibromomethane
111-44-4
594-72-9
77-73-6
111-40-0
3710-84-7
96-22-0
75-61-6
1985
1978
1973
1985
2012
1995
1962
5
2
5
1
2
200
100
45
46
108-83-8
3033-62-3
1979
1997
25
0.05
47
48
49
Diglycidyl ether
bis(2Dimethylaminoethyl)ether
Dimethyl carbamoyl chloride
Dimethyl disulfide
Dimethylethoxysilane
79-44-7
624-92-0
14857-34-2
2006
2006
1991
0.005
0.5
0.5
50
51
52
53
54
55
1,1 Dimethylhydrazine
Dimethyl sulfate
Dimethyl sulfide
Dodecyl mercaptan
Ethanolamine
Ethyl tert-butyl ether
57-14-7
77-78-1
75-18-3
112-55-0
141-43-5
637-92-3
1993
1985
2001
2001
1985
2012
0.01
0.1
10
0.1
3
25
56
Ethyleneimine
151-56-4
2008
0.05
57
58
59
60
61
Ethyl formate
Ethyl isocyanate
Ethyl mercaptan
N-ethylmorpholine
Ethyl silicate
109-94-4
109-90-0
75-08-1
100-74-3
78-10-4
2011
2013
2003
1985
1979
100
0.02
0.5
5
10
62
Formamide
75-12-7
1985
10
63
64
65
66
67
68
Furfuryl alcohol
Glycidol
Hexachlorocyclopentadiene
Hexanediamine
sec-Hexyl acetate
Hexylene glycol
98-00-0
556-52-5
77-47-4
124-09-4
108-84-9
107-41-5
1979
1993
1979
1990
1963
1974
10
2
0.01
0.5
50
C 25
URT & eye irr
URT & Eye irr
Eye & URT irr
URT & eye irr;
testicular dam
URT & eye irr
URT & eye irr; liver &
kidney dam
URT & eye irr, nausea
URT irr
URT, LRT, &eye irr
URT & eye irr
URT irr
URT irr, CNS impair
URT irr, CNS impair,
liver dam
URT & eye irr
URT, eye, & skin irr
Nasal cancer, URT irr
URT irr, CNS impair
URT & eye irr;
headache
URT irr; nasal cancer
Eye &URT irr
URT irr
URT irr
Eye & skin irr
URT irr; kidney dam
(nephropathy);
cochlear impair
URT irr, liver& kidney
dam
URT irr
URT & eye irr
URT irr; CNS impair
URT irr; eye dam
URT & eye irr, kidney
dam
Eye & skin irr; kidney &
liver dam
URT & eye irr
URT, eye, & skin irr
URT irr
URT & skin irr
Eye & URT irr
Eye & URT irr
69
70
71
72
73
74
75
999-61-1
26952-21-6
108-20-3
4016-14-2
463-51-4
79-41-4
34590-94-8
1997
1990
1979
1979
1962
1992
1979
0.5
50
250
50
0.5
20
100
Eye irr; eye dam
URT irr
Eye & URT irr
URT & eye; dermatitis
URT irr; pulm edema
Skin & eye irr
Eye & URT irr; CNS
impair
76
77
78
2-Hydroxypropyl acrylate
Isooctyl alcohol
Isopropyl ether
Isopropyl glycidyl ether
Ketene
Methacrylic acid
2(Methoxymethylethoxy)prop
anol
Methyl acrylate
Methylal
Methyl cyclohexane
96-33-3
109-87-5
108-87-2
1997
1970
1962
2
1000
400
79
80
Methylcyclohexanol
o-Methylcyclohexanone
25639-42-3
583-60-8
2005
1970
50
50
81
Methyl ethyl ketone peroxide
1338-23-4
1992
C 0.2
82
83
Methyl formate
Methyl hydrazine
107-31-3
60-34-4
2014
1991
50
50
84
Methyl isobutyl carbinol
108-11-2
1966
25
85
Methyl methacrylate
80-62-6
1992
50
86
87
Methyl silicate
Methyl vinyl ketone
681-84-5
78-94-4
1978
2009
1
C 0.2
88
89
90
Monochloroacetic acid
Morpholine
Naphtalene
79-11-8
110-91-8
91-20-3
2005
2005
2013
0.5
20
10
91
Nitroethane
79-24-3
1979
100
92
1-Nitropropane
108-03-2
1992
25
93
94
Perchloromethyl mercaptan
Perfluoroisobutylene
594-42-3
382-21-8
1988
1989
0.1
C 0.01
95
96
97
Phenyl ether
Phenyl isocyanate
Phosgene
101-84-8
103-71-9
75-44-5
1979
2014
1992
1
0.005
0.1
98
99
Phtalic anhydride
2-Propanol
85-44-9
67-63-0
1992
2001
1
200
100
Propargyl alcohol
107-19-7
1992
1
Eye, skin
Eye irr; CNS impair
URT irr; CNS impair;
liver & kidney dam
URT & eye irr
URT &eye irr; CNS
impair
Eye & skin irr; liver &
kidney damage
CNS impair; URT irr
URT & eye irr; lung
cancer; liver dam
URT & eye irr; CNS
impair
URT & eye irr; body
weight eff; pulm
edema
URT irr; eye dam
URT & eye irr; CNS
impair
URT irr
Eye dam; URT irr
URT irr; cataracts;
hemolytic anemia
URT irr; CNS impair;
liver dam
URT &eye irr; liver
dam
Eye & URT irr
URT irr; hematologic
eff
URT & eye irr; nausea
URT irr
URT irr; pulm edema;
pulm emphysema
URT, eye &skin irr
Eye & URT irr; CNS
impair
Eye irr; liver & kidney
101
102
103
104
Proprionaldehyde
Propionic acid
Propylene
Propylene dichloride
123-38-6
79-09-4
115-07-1
78-8-5
1998
1977
2005
2005
20
10
500
10
105
106
107
108
109
Propylene oxide
Propyleneimine
Quinone
Resorcinol
1,1,2,2,-Tetrabromoethane
75-56-9
75-55-8
106-51-4
108-46-3
79-27-6
2000
2008
1970
1992
2005
2
0.2
0.1
10
0.1
110
Tetrahydrofuran
109-99-9
2002
50
111
Tetranitromethane
509-14-8
1992
0.005
112
113
114
Trichloroacetic acid
1,2,4-Trichlorobenzene
Vinyl acetate
76-03-9
120-82-1
108-05-4
2013
1975
1992
0.5
C5
10
110dam
URT irr
Eye, skin & URT irr
Asphyxia; URT irr
URT irr; body weight
eff
Eye & URT irr
URT; kidney damage
Eye irr; skin dam
Eye & skin irr
Eye & URT irr; pulm
edema; liver dam
URT irr; CNS impair;
kidney dam
Eye & URT irr; URT
cancer
Eye & URT irr
Eye & URT irr
URT, eye & skin irr, CNS
impair
Notes: Prepared by Yves Alarie, Ph.D. University of Pittsburgh, 2015.
1. From: Booklet of The American Conference of Governmental Industrial Hygienists (ACGIH) (2015). TLVs and
BEIs Based on the Documentation of the Threshold Limit Values for Chemical Substances and Physical
Agents & Biological Exposure Indices. For each chemical listed the last Documentation Date is listed as given
in the 2015 Booklet.
2. The number listed is for TLV-TWA or STEL and the notation Ceiling (C) if applicable. When both a TLV-TWA
and TLV-Ceiling are given, the lowest value is entered. Note that for some chemicals a revision is
contemplated, so check the last publication year of the Booklet.
3. The abbreviation, as written in the Booklet: URT: Upper respiratory tract; irr: irritation; CNS: Central
Nervous System; impair: impairment; LRT: Lower respiratory tract; eff: effects; pulm: pulmonary; func:
function.