CALCIUM GUIDELINE 1. Definition Calcium is an essential mineral found in great abundance in the body. Ninety-nine percent of all the calcium in the body is found in the bones and teeth. The remaining one percent is in the blood. Role/Function Calcium plays important roles in nerve conduction/ nerve impulse transmission, , Bone Structure (99%), Regulator of Metabolism (1%), muscle contraction, and blood clotting,. Some studies suggest that calcium, along with vitamin D, may have benefits beyond bone health, perhaps protecting against cancer, diabetes and high blood pressure. But evidence about such health benefits is not definitive. Regulation of Blood Calcium10 mg/dl of blood hypocalcemia & hypercalcemia abnormal muscle cramping nerve irritation Controlled by: vitamin D, parathyroid hormone, calcitonin 2. Source of Calcium: 99% of the body’s calcium supply is stored in the bones and teeth where it supports their structure and function a) Calcium and diet Your body doesn't produce calcium, so you must get it through other sources. Calcium can be found in a variety of foods, including: Dairy products, such as cheese, milk and yogurt Dark green leafy vegetables, such as broccoli and kale Fish with edible soft bones, such as sardines and canned salmon Calcium-fortified foods and beverages, such as soy products, cereal and fruit juices Even if you eat a healthy, balanced diet, you may find it difficult to get enough calcium if you: Follow a vegan diet Have lactose intolerance and limit dairy products 1 Consume large amounts of protein or sodium, which can cause your body to excrete calcium Have osteoporosis Are receiving long-term treatment with corticosteroids Have certain bowel or digestive diseases that decrease your ability to absorb calcium, such as inflammatory bowel disease or celiac disease In these situations, calcium supplements may help you meet your calcium requirements. Table: Selected Food Sources of Calcium Food Milligrams (mg) per serving Percent DV* Yogurt, plain, low fat, 8 ounces 415 42 Mozzarella, part skim, 1.5 ounces 333 33 Sardines, canned in oil, with bones, 3 ounces 325 33 313–384 31–38 Cheddar cheese, 1.5 ounces 307 31 Milk, nonfat, 8 ounces** 299 30 Soymilk, calcium-fortified, 8 ounces 299 30 Milk, reduced-fat (2% milk fat), 8 ounces 293 29 Milk, buttermilk, lowfat, 8 ounces 284 28 Milk, whole (3.25% milk fat), 8 ounces 276 28 Orange juice, calcium-fortified, 6 ounces 261 26 Tofu, firm, made with calcium sulfate, ½ cup*** 253 25 Salmon, pink, canned, solids with bone, 3 ounces 181 18 Cottage cheese, 1% milk fat, 1 cup 138 14 Tofu, soft, made with calcium sulfate, ½ cup*** 138 14 100–1,000 10–100 103 10 99 10 Kale, raw, chopped, 1 cup 100 10 Kale, fresh, cooked, 1 cup 94 9 Ice cream, vanilla, ½ cup 84 8 Chinese cabbage, bok choi, raw, shredded, 1 cup 74 7 Bread, white, 1 slice 73 7 Pudding, chocolate, ready to eat, refrigerated, 4 ounces 55 6 Tortilla, corn, ready-to-bake/fry, one 6” diameter 46 5 Tortilla, flour, ready-to-bake/fry, one 6” diameter 32 3 Yogurt, fruit, low fat, 8 ounces Ready-to-eat cereal, calcium-fortified, 1 cup Frozen yogurt, vanilla, soft serve, ½ cup Turnip greens, fresh, boiled, ½ cup 2 Table: Selected Food Sources of Calcium Food Milligrams (mg) per serving Percent DV* Sour cream, reduced fat, cultured, 2 tablespoons 31 3 Bread, whole-wheat, 1 slice 30 3 Broccoli, raw, ½ cup 21 2 b) Calcium RDA: 1998 RDA’s (AI) 1300 mg/d : children & teens 1000 mg/d : adults 1200 mg/d : older Usual intakes are low c) Calcium and vitamin D Your body needs vitamin D to absorb calcium. For this reason, some calcium supplements contain vitamin D. A few foods naturally contain small amounts of vitamin D, such as canned salmon with bones, and egg yolks. You can also get vitamin D from fortified foods and sun exposure. The RDA for vitamin D is 600 international units (15 micrograms) a day for most adults . d) calcium supplements: Several different kinds of calcium compounds are used in calcium supplements. Each compound contains varying amounts of the mineral calcium — referred to as elemental calcium. The two main forms of calcium supplements are carbonate and citrate. Calcium carbonate is cheapest and therefore often a good first choice. Other forms of calcium in supplements include gluconate and lactate. In addition, some calcium supplements are combined with vitamins and other minerals. For instance, some calcium supplements may also contain vitamin D or magnesium. Check the ingredient list to see which form of calcium your calcium supplement is and what other nutrients it may contain. This information is important if you have any health or dietary concerns. 3. Calcium Deficiency a) Groups at Risk of Calcium Inadequacy Although frank calcium deficiency is uncommon, dietary intakes of the nutrient below recommended levels might have negative health consequences over the long term. The following groups are among those most likely to need extra calcium. 3 Postmenopausal women Menopause leads to bone loss because decreases in estrogen production both increase bone resorption and decrease calcium absorption Amenorrhea women and the female athlete triad Amenorrhea, the condition in which menstrual periods stop or fail to initiate in women of childbearing age, results from reduced circulating estrogen levels that, in turn, have a negative effect on calcium balance. Individuals with lactose intolerance or cow’s milk allergy Lactose intolerance refers to symptoms (such as bloating, flatulence, and diarrhea) that occur when one consumes more lactose, the naturally occurring sugar in milk, than the enzyme lactase produced by the small intestine can hydrolyze into its component monosaccharides, glucose and galactose [37]. Cow’s milk allergy is less common than lactose intolerance, affecting 0.6% to 0.9% of the population [44]. People with this condition are unable to consume any products containing cow’s milk proteins and are therefore at higher risk of obtaining insufficient calcium. To ensure adequate calcium intakes, lactose-intolerant individuals and those with cow’s milk allergy can choose nondairy food sources of the nutrient (such as kale, bok choy, Chinese cabbage, broccoli, collards and fortified foods) or take a calcium supplement. Vegetarians: Vegetarians might absorb less calcium than omnivores because they consume more plant products containing oxalic and phytic acids Osteoporosis Risk Factors Genetics Family History Ethnicity Caucasian > Asian > Blacks Risk Factors b) Chronic Calcium Deficiency Lack of Exercise Sings/Symptom Inadequate intakes of dietary calcium from food and supplements produce no obvious symptoms in the short term. Circulating blood levels of calcium are tightly regulated. Hypocalcemia results primarily from 4 medical problems or treatments, including renal failure, surgical removal of the stomach, and use of certain medications (such as diuretics). Symptoms of hypocalcemia include numbness and tingling in the fingers, muscle cramps, convulsions, lethargy, poor appetite, and abnormal heart rhythms. If left untreated, calcium deficiency leads to death. Over the long term, inadequate calcium intake causes osteopenia which if untreated can lead to osteoporosis. The risk of bone fractures also increases, especially in older individuals. Calcium deficiency can also cause rickets, though it is more commonly associated with vitamin D deficiency [1]. 4. Recommended Daily Allowance: a) WHO recommendation for pregnant women 5 b) Recommendation for other ages:………………………………………………………………………… 5. Guideline for Prevention and Treatment ………………………………………………………………………. Calcuim dosage for differenct ages مقدارتوصیه شده روزانه عمربه سال 6 700 mg 1–3 1000 mg 4–8 1300 mg 9 – 18 1000 mg 19 – 50 1000 mg ( مردهاM) 1200 mg ( زنهاF) 51 – 70 1200 mg > 70 1000 mg مادران حامله وشیرده ساله۱۹باالتراز 6. calcium supplements Toxicity : Calcium supplements aren't for everyone. For instance, if you have a health condition that causes excess calcium in your bloodstream (hypercalcemia), you should avoid calcium supplements. Dietary calcium is generally safe, but more isn't necessarily better, and excessive calcium doesn't provide extra bone protection. In fact, if the calcium in your diet and from supplements exceeds the tolerable upper limit, you could increase your risk of health problems, such as: Kidney stones Prostate cancer Constipation Calcium buildup in your blood vessels Impaired absorption of iron and zinc If you take calcium supplements and eat calcium-fortified foods, you may be getting more calcium than you realize. Check food and supplement labels to monitor how much calcium you're getting a day and whether you're achieving the RDA but not exceeding the recommended upper limit. some images if you prefer to be add? 7 References 1. Committee to Review Dietary Reference Intakes for Vitamin D and Calcium, Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: National Academy Press, 2010. 2. U.S. Department of Agriculture, Agricultural Research Service. 2011. USDA National Nutrient Database for Standard Reference, Release 24. Nutrient Data Laboratory Home Page, http://www.ars.usda.gov/ba/bhnrc/ndl . 3. U.S. Department of Agriculture, Center for Nutrition Policy and Promotion. ChooseMyPlate.gov , 2011. 4. Straub DA. Calcium supplementation in clinical practice: a review of forms, doses, and indications. Nutr Clin Pract. 2007;22:286-96. [PubMed abstract] 5. Andon MB, Peacock M, Kanerva RL, De Castro JAS. Calcium absorption from apple and orange juice fortified with calcium citrate malate (CCM). J Am Coll Nutr 1996;15:313-6. [PubMed abstract] 6. Bailey RL, Dodd KW, Goldman JA, Gahche JJ, Dwyer JT, Moshfegh AJ, Sempos CT, Picciano MF. Estimation of total usual calcium and vitamin D intakes in the United States. J Nutr. 2010 Apr;140(4):817-22. [PubMed abstract] 7. Ervin RB, Wang C-Y, Wright JD, Kennedy-Stephenson J. Dietary intake of selected minerals for the United States population: 1999-2000. Advance Data from Vital and Health Statistics, number 341. 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