The Circulatory and Lymphatic Systems Blood is a fluid that circulates throughout the body. It carries ___________________________________________________________________________ to body cells. It carries _____________________________________________________________ taken up by respiratory system. It ____________________________________________________________________ produced by cell metabolism The human body contains approx _____________________________________ of blood. Blood consists of: A fluid component called _____________________________________________________________. And formed elements: _______________________________________________________ cells _______________________________________________________ cells ___________________________________________________________ Plasma: Makes up _________________________________________________________________________________ Is a yellowish liquid (________________________________________________________________) in which red blood cells, white blood cells and platelets are in suspension. Also contains ____________________________________________________________________________________ . _______________________________________________________________________________________________ Red blood cells: Are ___________________________________________________________________ and lack a nucleus Contain a _____________________________________________________________ called Hemoglobin Are produced in the ____________________________________________________________________ ________________________________________________________________________of blood volume Oxygenated blood carries oxygen and is ____________________________________________________________ Deoxygenated blood depleted of oxygen, carrying carbon dioxide and is ____________________________________. White blood cells: – Also called _______________________________________________________ – Are colourless 1 – _________________________________________________________________ red blood cells White blood cells ____________________________________________________________________: ___________________________________________________ dead or damaged cells, old red cells, and microorganisms Produce antibodies to neutralize invading organisms Platelets: are ____________________________________________________________________________ Important in the _______________________________________ (clotting –the process whereby the ____________________________________________ and start the formation of __________________ __________________________________________ to form a solid mass (a clot) and stop the bleeding) Blood Groups Red blood cells have ________________________________________________________, called antigens that provoke a ______________________________________________ when they are introduced into another body. Blood is grouped according to the ____________________________________________________________ it contains and by the ____________________________________________________________________ Blood typing is _____________________________________________________________________________ A blood transfusion is the injection blood products (usually __________________) from one person to another. Blood Type A: ______________________________________________________________________________________ Blood Type B: ______________________________________________________________________________________ Blood Type AB: ____________________________________________________________________________________ Blood Type O: _____________________________________________________________________________________ The Rhesus (Rh) factor This Rh factor is another antigen determining the ________________________________________________________ _________________________________________________________________________________________________ – Rh+ means the __________________________________________________________________ – Rh - means the _________________________________________________________________ 2 The Anatomy of the Circulatory System The circulatory system consists of: the heart Blood vessels -arteries -capillaries -veins The Blood Structure of the Heart Over a lifespan of 80 years the heart beats more than 3 billion times The heart has 4 chambers: – Right and left atrium (1st chambers that blood _____________________________________________) – Right and left ventricle (last chamber before blood _________________________________________) Blood vessels are the plumbing of the body that assure the __________________________________________ ___________________________________________________________________________________________ Two blood vessels leave the ventricles: The Pulmonary artery –blood is pumped __________________________________________________. The Aorta – blood is pumped ___________________________________________________________. Two vessels enter the atria: The Pulmonary veins – bring blood ______________________________________________________. The Vena Cava – bring blood back _______________________________________________________. Blood Vessels of the Body Arteries ________________________________________________________________________ to the organs of the body. Have ____________________________________________________________________ to withstand high pressure. The ______________________________________________________________________ in the body. It___________ _____________________________________ and branches to supply upper and lower body. 3 These large arteries progressively branch and get smaller and smaller, becoming-____________________________ ________________________________________________________________________________________________ Capillaries are minute branches at the ends of the arteries and veins. They are ______________________________________________________________________________________ into all body cells which are within 50µm of a capillary. Veins ____________________________________________________________________________ and have thinner walls and are less elastic than the arteries because there is less pressure. To help the blood to flow up from the extremities (e.g. legs), veins have ________________________ prevent backflow. ____________________________________________________________________ “pump” the blood back to the heart. Capillaries turn into _________________________________________________________________________ returning to left atrium via the ___________________________________________________________. When a heart beats it first _________________________________________ and then __________________________ 1. Deoxygenated blood returns under pressure via the Vena Cava into the _______________________________ _________________________________________________________________________________________ 2. Contraction of right atrium forces blood into the _________________________________________________. 3. Ventricular contraction forces blood through the __________________________________________ (only artery carrying deoxygenated blood) into _____________________________________________________. Blood travels through smaller ______________________________ then _____________________________ and finally the _____________________________________________ in single file. The capillaries surround the ___________________________________________________________ and allow the exchange of gases (O2, CO2) between ________________________________________________________________. Oxygenated blood leaves the _______________________________________________, first through the ________________________________, then _________________________ returning to the ____________________ via the pulmonary vein. Contraction of the ______________________________ forces the blood into the _______________________________. 4. Contraction of the _______________________________ forces the blood through the ______________________________________________________________ throughout the body. 4 Arteries branch off the aorta and supply various organs and tissues with _______________________________________ Arterioles Capillaries – exchange of gases Venules Veins Vena cava Blood pressure is the force with which the blood is pushing against the arterial walls. Bp is measured in mm of mercury (mm Hg) The systolic pressure is when the _______________________________________ and the vessels are expanded. The diastolic pressure is when the ________________________________________________ (no contraction). The pressure is given as a ratio of systolic diastolic 120 80 (for adolescents normal bp is 113 mm Hg) 65 The Lymphatic System ___________________________________________________________________ to the cells _____________________________________________________________________ products plays an important role in the ____________________________________________________ __________________________________________ between the blood vessels and the body cells A fluid derived from the blood Lymph is: Lymphatic vessels _____________________________________________________ and are close to them The lymph ____________________________________________________________________________ via 2 veins near the heart. The lymph ______________________________________________________________________ for circulation. The lymphatic system comprises of the following organs: The ______________________________________________________- found underneath the heart The ________________________________________________________- found in long bones (femur) 5 The ________________________________________________- found left of stomach under diaphragm The ________________________________________________- found in mouth bordering the pharynx The lymphatic vessels have ___________________ ______________________________________ throughout the body. When an infection occurs these __________________________________________________ (e.g. A cold or tonsillitis) The immune system The immune system is made of: The vessels and organs of the _________________________________________________________ The ______________________________________________________________________________ The ________________________________________________________ against antigens is called immunity. Antigens are _______________________________________________________________ or other substances that produce an immune reaction. An antibody is a substance produced by certain white blood cells that can neutralize specific antigens. The immune response can be _______________________________________________________________________ _______________________________________________________________________. Non specific immune response The Non specific immune response is the ________________________________________________ against ______________________________________________________________________________________. The ___________________________________________________________________________ against antigens (bacteria, viruses, etc) and is involved in the non specific immune response. An example of a non specific immune response is getting ___________________________________________ ________________________________________________________________________________________. Specific Immune response The Specific immune response is the __________________________________________________ against a _____________________________________________________________________________________. Some white blood cells produce ____________________________________________________________. Antibodies against the cold virus are ____________________________________ as ones against other bacteria. Bacteria (or viruses) invade the body 6 ___________________________________________________________________ are produced by leucocytes Antibodies _____________________________________________________________________ to the bacteria white blood cell __________________________________________________________________ bacteria Immunity can be acquired in two ways: – Naturally – by _______________________________________________ to an antigen (diseases, etc) and _____________________________________________________________. Your body produces antibodies that will protect you against that disease – Vaccine – contains ______________________________________________________________ that cause the white blood cells to _______________________________________________ against that disease. 7