Zoology 106 course General Animal Biology For Premedical Student By Dr. Ashraf M. Ahmed 1429-1430H 1 Questions Considered • • • • Why do certain reactions occur? Why do others not occur? What drives these processes? Why do organic molecules have certain properties? • Can we predict the presence or absence of certain properties? • Can we make new materials with other desired properties? 2 Roles • • • • • • My role Professor Guide Your Role Student Understand the material! 3 Homework • • • • • • Every problem in the Text is assigned. However, They will not be graded. They will not be collected. They will not be discussed in class. They are available to you to determine if you understand the material. 4 Attendance • • • • • • Assumption: you are adult students Attendance in lecture is expected Attendance at tests is expected. A missed examination will receive a zero. No excuses will be accepted. A missed final exam will receive a zero. 5 A Word on the Final Exam 6 Communication in Class • During my class you should • Turn your cell phone off. • Turn your desire to communicate with anyone but me off. 7 Expectations • • • • • • • • A professional student is expected to attend class purchase course materials study do the homework be prepared for class be prepared for tests do well 8 Doing Well • • • • • • • • • • • Read the chapter before lecture Attend lecture Take notes Do not rely on copies of Power Points Re-read the chapter after lecture Review lecture notes daily Rewriting the lecture notes is strongly suggested Keep, maintain, and study note cards Do homework problems. Form a study group Learn the functional groups 9 Good Luck Dr. Ahmed Abdel.Zaher 10 Types The Cell Cellulae (Small room) of cells The Organism’s Basic Unit of Structure and Function متقدمة بدائية Prokaryotic Micro-organisms الكائنات الدقيقة Eukaryotic All other forms of life 11 Cell Theory 1- All organisms are composed of one or more of cells. 2- Cell is the basic unit of life. 3- The new cell arises only from preexisting cell. 12 1). Prokaryotic and eukaryotic cells differ in size and complexity Similarities أوجه التشابه All cells are surrounded by a plasma membrane غشاء بالزمى. The semi-fluid substance المادة النصف سائلةwithin the cell is called “cytosol”, السيتوبالزمcontaining the cell organelles ِعضيات الخلية. All cells contain chromosomes which have genes in the form of DNA. All cells have tiny organelles عضيات صغيرةcalled “Ribosomes” that make proteins. Page 112 1). Prokaryotic and eukaryotic cells differ in size and complexity Differences أوجه اإلختالف A major difference الفرق األساسىbetween prokaryotic and eukaryotic cells is the location of chromosomes موضع الصبغيات. In an eukaryotic cell, chromosomes are contained in a true nucleus () النواة. In a prokaryotic cell, the DNA is concentrated in the nucleoid ()شـبه نواة without a membrane ( ) بدون غـشاءseparating it from the rest of the cell. In prokaryotic cell, DNA is a single strand ( )أحادى الشريطor double strand ( )ثنائى الشريطDNA. But in eukaryotic cell, DNA is double strand. Page 112 (A)- Prokaryotes الكائنات وحيدة الخلية ذات النواة البدائية األحياء الدقيقة Micro-organisms Page 112, 526 Types of Prokaryotes Prokaryotes Bacteria - Exist in most environments Archaea - Exist in extreme environments ( البيئات القاسيةhot and salty) They are differing in some other structural, biochemical and physiological characteristics صفات Page 526 Prokaryotes 1- Bacteria شبه نواة الريبوزومات غشاء بالزمى الجدار الخلوى الكبسولة األسواط Fig. 7.4 The prokaryotic cell is much simpler in structure, lacking a nucleus and the other membrane-enclosed organelles of the eukaryotic cell. Page 112 Prokaryotic Cell Plasma membrane Ribosomes Nucleoid Cell Wall Cytoplasm (Cytosol) Capsule A) the bacterial capsule Many prokaryotes (bacteria) secrete a sticky protective layer called capsule outside the cell wall, which has the following functions وظائف: 1. 2. 3. 4. Adhere تثبيتbacteria cells to their substratum السطح. Increase bacteria resistance المقاومةto host defenses مناعة العائل. Stick ) )تلصقbacterial cells together when live as colonies. Protect تحمىbacterial cell. Fig. 27.6 B) The bacterial cell wall In all prokaryotes, the functions of the cell wall are as following: 1. maintains تحافطthe shape of the cell, 2. affords physical protection توفر الحماية الطبيعية 3. prevents the cell from bursting ( )إنفجارin a hypotonic environment البيئة ذات الضغط األسموزى المنخفض. Most bacterial cell walls contain peptidoglycan (a polymer of modified sugars cross-linked by short polypeptides). The walls of Archaea lack ( )تـفـتـقـدpeptidoglycan. The Gram’s stain: صبغة جرام It is a tool for identifying تعريفspecific bacteria, based on differences in their cell walls. A)- Gram-positive (Gram +ve) bacteria: Their cell walls have large amounts كمية كبيرةof peptidoglycans that react with Gram’s stain (appear violet-stained )تـُصبغ بنفسجيا. Fig. 27.5a Page 529 The Gram’s stain: صبغة جرام B)- Gram-negative (Gram -ve) bacteria: their cell walls have no or small amount of peptidoglycan. So, do not react or very weakly react with Gram’s stain (do not appear stained )ال تظهر الصبغة Fig. 27.5b Page 529 Gram Staining of Bacteria Gram +ve bacteria: have Large amount of peptidoglycan that stained violet (non-pathogenic )غير ممرضة. Gram –ve bacteria: Have small amount or no peptidoglycan (no staining) (pathogenic )ممرضة. Gram-negative species are pathogenic ( ) ممرضةmore threatening ( )أكثر خطورةthan gram-positive species. Gram-negative bacteria are commonly more resistant ()أكثر ممانعة than gram-positive species to antibiotics للمضادات الحياتية. Reproduction of Bacteria التكاثر فى البكتريا Prokaryotes reproduce ( )تـتـكاثرonly asexually ()ال جنسيا by binary fission ()اإلنقسـام الثـنائى البسيط. A single cell produce a colony of offspring. Fig. 27.9 Page 531 Mov Nutrition of Prokaryotes التغذية فى األحياء الدقيقة Nutrition refers to how an organism obtains energy and a carbon source from the environment to build the organic molecules of its cells. • Prokaryotes are grouped (صنٍفـَت ُ ) into four categories ( )أنواعaccording to how they obtain energy and carbon Nutrition of Prokaryotes التغذية فى األحياء الدقيقة Phototrophs ()ضوئية التغذية: Chemotrophs ()كيميائية التغذية: Organisms that obtain energy from light. Organisms that obtain energy from chemicals in their environment. Autotrophs ()ذاتية التغذية: Heterotrophs ()متعدد التغذية: a carbon source. Organisms that use CO2 as a carbon source. Organisms that use organic nutrients as There are four major modes of nutrition Photoautotrophs ()ذاتية التغذية الضوئية: use light energy as energy source, and CO2 as carbon source to synthesis ( )تخلقorganic compounds. Chemoautotrophs ))ذاتية التغذية الكيميائية: use chemical inorganic substances as energy source, and CO2 as a carbon source. Photoheterotrophs ()متعدد التغذية الضوئية: use light as energy source, and organic substances as carbon source. Chemoheterotrophs ()متعدد التغذية الكيميائية: use organic substances as a source for both energy and carbon. Prokaryotic modes of nutrition Based on Carbon source and Energy source that can be used by a prokaryote organism to synthesise organic compounds. Prokaryotes Page 532 Autotrophs CO2 as Carbon Source Photoautotroph Chemoautotroph Heterotrophs Organic compounds as Carbon ( C) Source PhotoHeterotroph ChemoHeterotroph - Light as energy source - Chemicals as energy source - Light as energy source - Chemicals as energy source -CO2 as C source -CO2 as C source -Organic compounds as C source - Organic compounds as C source