Biology 2nd Semester 2013 Study Guide – More Terms to Know Genetics (Chapters 10 and 11) Crossing Over Exchange of segments of DNA between a pair of homologous chromosomes during prophase I of meiosis. Gamete Another name for sperm and egg cells. A gamete has ½ the genetic material as the parent cell. Sperm and egg cells combine to form a fertilized egg during meiosis. Fertilization The process by which egg and sperm combine to produce a new cell. Gregor Mendel A scientist who lived in the 1800’s and studied how traits are inherited using pea plants. Mitosis . The cell division process that produces 2 cells genetically identical to the parent cell. 2 IDENTICAL ↗ Meiosis The cell division process that occurs only in sexually reproducing organisms. Produces 4 gametes, each one is genetically unique. Assures genetic variation in organisms ↖ 4 DIFFERENT Genetics (Chapters 12 & 13) DNA DNA stands for deoxyribonucleic acid o Made of nucleotides A nucleotide has three parts: A phosphate group A five-carbon (pentose) sugar called deoxyribose A nitrogen base o Adenine (A) Nucleotide o Guanine (G) o Cytosine (C) o Thymine (T) DNA Replication the DNA process of making an exact copy of itself. nitrogen bases are complementary o A bonds with T o G bonds with C Original strand → CTGGAC New strand → GACCTG DNA Mutations A permanent change in a cell’s DNA. Produces a protein different from the original. How proteins are made DNA Takes place Transcription in the nucleus RNA Translation Protein in the ribosome Transcription is the process that makes messenger RNA (mRNA). Translation is the process that translates the nucleotides to amino acids (proteins). DNA vs RNA • • • • • • Deoxyribonucleic acid Contains genetic information Has 2 STRANDS Contains the sugar DEOXYRIBOSE Nitrogen bases = guanine, cytosine, adenine and THYMINE G matches with C and A matches with T How are DNA and RNA the same? Both have nucleic acids Both have guanine, cytosine, and adenine Both made of nucleotides Both have phosphate groups • • • • • • Ribonucleic acid Contains information to make proteins Has only a SINGLE STRAND Contains the sugar RIBOSE Nitrogen bases = guanine, cytosine, adenine and URACIL G matches with C and A matches with U How are DNA and RNA DIFFERENT? Codons • A nucleotide sequence (triplet) in DNA and RNA. When the original DNA strand makes a strand of mRNA----o A bonds with U o C bonds with G o AND…… T bonds with A Original DNA strand→ A C G T T A C T T A T T mRNA strand→ UGCAAUGAAUAA ↓ is made of ↓ Amino Acid Sequence Shown by first 3 letters, for example o Cysteine=Cys o Leucine=Leu o Lysine= Lys What is the Amino Acid Sequence for U G C A A U G A A U A A? Look at the Genetic Code→→→ o UGC=Cysteine o AAU=Asparagine o GAA= Glutamate o UAA= stop The Amino Acid Sequence → Cys-Asp-Glu-stop Genetic Code AND FINALLY …………. Humans share over 90% of their DNA with primates. Scientists believe humans and primates are similar because millions of years ago we had the same ancestor. GOOD LUCK ON YOUR FINALS! DK 5/2013