Medical Chemistry An extraordinary subject Applied chemistry for MEDICAL STUDENTS It spans from: – General Chemistry – Inorganic Chemistry – Analytical Chemistry – Organic Chemistry To: – Biochemistry – Physiology – Pharmacology Organization of our curriculum General chemistry (physical chemistry) (McMurray, Fay: Chemistry, 4th Edition; Darrel D. Ebbing: General Chemistry) All other similar texbooks can be used Organic and bioorganic chemistry (P. Gergely: Organic and Bioorganic Chemistry For Medical Students, 3rd Edition) Analytical Chemistry: Practices and seminars only! (G. Oszbach: Laboratory Experiments in Medical Chemistry, 1998) Bioinorganic Chemistry: Obligatory subject (P. Gergely: Introduction to Bioinorganic Chemistry for Medical Students) Elective course (2 credits) (W. Kaim, B. Schwederski: Bioinorganic Chemistry: Inorganic Elements in the Chemistry of Life) Laboratory Safety Chemistry laboratory can be a DANGEROUS PLACE to work in Eye safety: ALWAYS wear approved safety glasses or goggles Further rules and regulations will be discussed on the first meeting with lab instructors: Group Group Group Group Group Group Group 1: 2: 3: 4: 5: 6: 7-8: Dr. Zoltán Berente Dr. Veronika Nagy Ms. Erika Turcsi Dr. Veronika Nagy Dr. Tamás Lóránd Dr. Attila Agócs Dr. László Márk Intranet Medical Chemistry lectures and exam samples can be found at the following link: http://intranet.pote.hu/OKTATAS/biokemia/ medical_chemistry.html Chemistry The science that is concerned with the characterization, composition, and transformations of matter Development of modern chemistry 1. Practical arts (-to 600 B.C.) Ancient Egypt and Mesopotamia – – – – Production of metals from ores Manufacture of Pottery Brewing, baking Preparation of medicines, drugs and dyes 2. Greek (600 B.C. to 300 B.C.) – Concept of four elements (earth, air, fire, water) – Atomic theory 3. Alchemy (300 B.C. to 1650 A.D.) Alexandria, Arabs – Chemical apparatus, laboratory operations – Philosopher’s stone, elixir of life – Iatrochemistry (a branch of alchemy concerned with medicine) 4. Phlogiston (1650 to 1790) Combustion: wood + oxygen gas (from air) containing gases ashes + oxygen According to the phlogiston theory: wood ashes + phlogiston (removed by air) WOOD = ASHES + PHLOGISTON 5. Modern Chemistry (1790- ) Antoine Lavoisier – Laws of chemistry – Modern terminology Main branches of chemistry Analytical chemistry: separation, identification, and composition of materials Organic chemistry: chemistry of the carbon compounds Inorganic chemistry: chemistry of the compounds other than carbon compounds Physical chemistry: study of the physical characteristics of materials and mechanisms of their reactions Biochemistry: chemistry of living systems Nuclear chemistry: chemistry of subatomic particles and nuclear reactions