Focus on PHARMACOLOGY ESSENTIALS FOR HEALTH PROFESSIONALS CHAPTER 3 Terminology, Abbreviations, and Dispensing Prescriptions Medical Terminology • Medical terminology originated primarily from Greek and Latin prefixes, roots, and suffixes, known as word parts. • Health-care professionals involved with pharmacology must be familiar with word building, common medical terms, and abbreviations. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Medical Terminology • A root is the main part of a word that gives the word its central meaning. • A prefix is a structure at the beginning of a word that modifies the meaning of the root. • A suffix is similar in function to a prefix, but appears at the end of a word. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Understanding Terminology Prefix + Root + Suffix Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Understanding Terminology Prefix + Root + Suffix Hypo + glyc + emia Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Understanding Terminology Prefix + Root + Suffix Hypo + glyc + emia Too little + sugar + blood condition Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Understanding Terminology Hypoglycemia Condition of low blood sugar levels Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.1 Selected Roots Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.2 Common Prefixes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-1 Some Common General Prefixes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.3 Common Suffixes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-2 Some Common General Suffixes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Combining Vowels • Medical terms are formed from many different word parts. • These parts are often joined by combining vowels. • The most common combining vowels are the letters o and i. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.4 General Pharmacy Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.4 (continued) General Pharmacy Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.5 Pharmacy Abbreviations—Directions/SIG Codes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.5 (continued) Pharmacy Abbreviations—Directions/SIG Codes Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.6 Pharmacy Abbreviations—Routes of Administration Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.7 Pharmacy Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.8 General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.8 (continued) General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-3 Abbreviations Commonly Used in Prescriptions Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-3 (continued) Abbreviations Commonly Used in Prescriptions Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-3 (continued) Abbreviations Commonly Used in Prescriptions Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-4 Abbreviations Commonly Used for Measurements Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-5 General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-5 (continued) General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-5 (continued) General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 3-5 (continued) General Medical Abbreviations Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.9 JCAHO’s “Minimum” Do Not Use List Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.10 JCAHO’s “Recommended” Do Not Use List Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Drug Names • Chemical name: chemical makeup of a drug; often very complicated • Generic name: also official, approved, or nonproprietary name; not protected by copyright • Proprietary name: also brand or trade name; assigned by manufacturers and protected by copyright Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Table 5.12 (continued) Common Brand-Name and Generic Prescription Drugs Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Sources of Drug Derivation Plants (e.g., alkaloids) Humans/animals (e.g., hormones) Minerals (e.g., sodium, iodine, etc.) Synthetics: manufactured (e.g., oral contraceptives) • Engineered: genetically engineered; (e.g., some insulins) • • • • Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Drug Forms • Classified by physical state (liquid, solid) and chemical composition • Determine whether action is local or systemic • Allow for oral, topical, mucosal, or parenteral (injectable) use Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Preparations for Oral Use • Oral drugs: solid or liquid forms • Form influences rate of dissolution and absorption • Liquids are more readily available for GI absorption than solids. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Solid Drugs • Pills: powdered drug mixed with liquid and rolled into round or oval shape • Tablets: powdered form of drug and bulk-filling material compressed under high pressure; various types include: – Chewable, sublingual, buccal, entericcoated, buffered, and sustained-release Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Al Dodge Figure 3-1 Solid drug forms. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Solid Drugs • Capsules: external shell usually made of gelatin contains drug in powder, granule, liquid, or combination form • Enteric-coating: prevents capsule or tablet from being dissolved in stomach where it may cause irritation; absorption occurs in intestines Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Solid Drugs • Caplets: shaped like capsules with form of tablets; film-coated for easy swallowing • Gelcaps: oil-based drug in soft gelatin capsules Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Al Dodge Figure 3-2 Examples of tablets. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Al Dodge Figure 3-3 Examples of capsules. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Al Dodge Figure 3-4 Examples of gelcaps. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Solid Drugs • Powders: dried and finely ground drugs • Granules: tiny pills usually in gelatin capsules; usually intended for gradual release • Troches or lozenges: flattened disks that may be hard or semisolid (e.g., cough suppressants) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Liquid Drugs • Syrups and linctuses: aqueous solutions containing high concentrations of sugars • Solutions: drugs dissolved in appropriate solvent • Elixirs: solutions of water, alcohol, and sugar Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Liquid Drugs • Infants and young children are not able to take solid drug forms such as tablets or capsules. Liquid drugs should be used. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Liquid Drugs • Fluid extracts: concentrated drug solutions from plant source mixed with suitable solvent, usually alcohol • Mixtures or suspensions: drug agent mixed with liquid but not dissolved; must be shaken before administration Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Liquid Drugs • Tinctures: alcoholic preparations of soluble drugs, usually from plant source • Emulsions: preparations combining two elements (such as oil and water) that cannot ordinarily be mixed • Spirits or essences: alcoholic liquids that may be used pharmaceutically as solvents Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Storing Drugs That Contain Alcohol • Elixirs, spirits, tinctures, and fluidextracts contain alcohol. • Keep them tightly sealed so that the alcohol cannot evaporate. • Store them in a dark place as specified on label. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Liquid Drugs • Aerosols: frequently delivered by oral inhalers or nebulizers for rapid absorption into blood circulation • Magmas: particles suspended in liquid; more pasty in consistency than other suspensions Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Topical Drugs: Semisolids • Creams: semisolids in both aqueous and oily base (e.g., benzoyl peroxide) • Ointments: similar to creams; used for local protective, soothing, astringent, or transdermal systemic effects (e.g., zinc oxide) • Plasters: combination liquids and powders that harden when dry (e.g., salicylic acid) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Topical Drugs: Liquids • Liniments: liquid suspensions for external application to skin • Gels or jellies: jellylike substances used for topical application • Lotions: suspensions of drugs in water base for external use Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Injectable Drugs • Provide rapid response; also called parenteral • Available as powders or solutions • Administered by following methods: – Intra-articular – Intradermal – Intramuscular (IM) – Epidural – Subcutaneous – Intravenous (IV) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Other Forms of Medications Ophthalmic: eye drops and ointments Otic: ear medications Nasal: nose drops or sprays Vaginal: solutions, creams, tablets, suppositories • Rectal: suppositories or enemas • Inhalation: anesthetic gases, compressed gases, bronchodilators • • • • Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Dorling Kindersley, Ltd Figure 3-5A Examples of otic drops. © Elena Dorfman. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Captured by Sarah Hill / Flickr / Getty Images Figure 3-5B Examples of ophthalmic drops. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Figure 3-5C Examples of nasal drops. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Safe Storage of Drugs • Do not expose medicines to sunlight, bright light, moisture, or extremes in temperatures. • Store insulin and vaccine preparations in a refrigerator according to the manufacturer’s directions. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Dispensing Drugs • Over-the-counter (OTC) drugs: available for self-medication; do not require prescription • Legend drugs: require prescription from licensed practitioner (physicians, dentists, veterinarians, etc.) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Contents of Prescriptions • • • • • • Name and address of patient and Date Address of prescriber’s office Medication prescribed (inscription) Rx symbol (superscription) Dispensing directions (subscription) Directions for patient (signa) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Contents of Prescriptions • Refill and special labeling • Prescriber’s signature, license or DEA number Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Figure 3-6 Example of a physician’s prescription. (A) The prescriber’s office name, address, and phone number. (B) The patient’s name, address, and date of prescription. (C) The super-scription (“Rx” symbol). (D) The inscription (names and quantities of ingredients). (E) The subscription (tells the pharmacist how many units of medication are needed). (F) The signature (Sig), which tells the patient how to take the medication. (G) Signature blank(s), where the prescriber signs. (H) The repetatur (which tells how many refills are allowed). Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Telephone Orders and Standing Orders • Prescribed by physicians who cannot be present at time of administration • Telephone orders: must be followed up with written drug order • Standing orders: ongoing prescriptions in hospitals, nursing homes, or residential care settings; must be signed and dated Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Hospital Drug Charts • Also known as physician order sheets; must be transcribed onto medication administration record (MAR) and include: – Approved drug names – All instances when drugs are administered or not administered (including reasons) – Nurse-initiated therapy (with physician countersignature) Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini Figure 3-7 Medical administration record as used in many hospitals. Focus on Pharmacology: Essentials for Health Professionals, Second Edition Jahangir Moini