BELL RINGER Explain what this picture represents. THE CELL CYCLE AND MITOSIS HOW CELLS MAKE NEW CELLS THAT ARE IDENTICAL TO THEMSELVES Cell Cycle- Regular pattern of growth, DNA replication and cell division that occurs in eukaryotic cells. Cycle is divided into 3 phases • Interphase • Mitosis • Cytokinesis Interphase • • Longest phase of the cell cycle Consists of 3 distinct periods • Gap 1 (G1)- cell carries out normal function, proteins are produced and organelles multiply • Synthesis (S)- DNA is duplicated • Gap 2 (G2)- cell carries out normal function and additional growth Checkpoints • • During G1 and G2 there are check points to ensure the cell is ready to continue growth and division. If the cell does not meet the requirements they move to G0- Holding tank Mitosis- the division of the cell nucleus and its contents. Mitosis has four stages Chromosome- one long continuous thread of DNA. Chromatid- half the X of a chromosome. The two sister chromatid are held together by a centromere. 1st Stage of Mitosis- Prophase • Chromatin forms chromosomes • Centrioles separate and move to opposite ends. • Nuclear envelop breaks down • Spindle fibers form and attach to centromeres 2nd stage of Mitosis- Metaphase • Chromosomes move to center of the cell • The site where chromosomes gather is called the metaphase plate 3rd Stage of Mitosis- Anaphase • Shortest stage of mitosis • Spindle fibers pull apart sister chromatids. • Chromatids move to opposite ends of the cell 4th Stage of Mitosis- Telophase • End of mitosis • Spindle fiber break apart • Nuclear envelope re-forms around chromosomes • Chromosomes begin to uncoil • 2 identical nuclei exist in the cell Cytokinesis • Last stage of the cell cycle • Division of cytoplasm after mitosis • Results in 2 identical daughter cells Binary Fission This is how Prokaryotes multiply Lytic Cycle Lysogenic Cycle Karyotyping is a test to examine chromosomes in a sample of cells, which help identify genetic problems as the cause of a disorder or disease.