Intro to Physiology

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Bio 342
Human Physiology
Theme of this course:
Homeostasis
Aging, infection,
injury, disease
Disturbed homeostasis
BIO 342 HUMAN PHYSIOLOGY
• PHYSIOLOGY: The study of the
function of cells, tissues, organs,
and organ systems.
• THE TEXT: Widmaier et al. 2011 (12th
ed.) & 2014 (13th edition)
– Chapter 2-5 review of other courses
– Using your textbook
– Using chapter questions from
Website
The Syllabus
(on the course website
http://webs.wofford.edu/davisgr/bio342/)
and Moodle Site for Grades and Electronic Assignments
• Office & cell phone numbers
• E-mail (davisgr@wofford.edu)
• Lecture topics by week
– Text chapters in parentheses
– Read in advance of lectures
– Check Moodle site 3x/wk at least
LABORATORIES
• May shift topics due to availability of animals
• One Lab Report in the form of abstracts
– very concise, based on lab data
– Incorporate statistics
– With revision and resubmission
• No separate lab tests; lab material included
on lecture tests
GRADING
• 3 lecture tests = 60%
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multiple multiple choice (choose all correct answers)
Some short answer in the space provided
Rarely fill in the blank
Sometime create or complete graph or diagram
discussion question(s) from a list
• Cumulative final exam = 20%
• Other work = 20%
– Abstract = 10%
– 1 Question Quizzes (1QQs) and other assignments
= 10%
Honor Code
• All worked is “pledged.”
• Issues of plagiarism to be handled by the
Honor Court.
• Work together, but submit your own work.
ODDS AND ENDS
• Limited use of electronics in classroom & lab
– Only for class/lab-related activities
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NO FOOD or DRINKS in Lab
BE ON TIME, READY TO GET TO WORK
DON’T ASK ABOUT LENGTH OF LAB
BE READY TO START ON TIME
RECORDING LECTURES BY PERMISSION WITH LIMITS
Study Questions & Quizzes
• Questions provided for each chapter
(On the website!)
• Read the book and answer the
questions PRIOR to class meeting
• Class time is used to deal with
problematical topics and reinforce the
major concepts
• Be ready for 1QQs
Study Questions & Quizzes
• Rationale for this format:
– See what Dr. Davis thinks you ought to emphasize
– Writing helps to consolidate memory and recall
– Greater effort results in better retention and
understanding
– Students are engaged learners
– Able to cover more information
Improve MCAT, DCAT and GRE scores

Sample 1QQ
Name on top edge, back side of paper
Answer on blank side of paper.
1.The 200+ cell types in the human
body can be classified into one of 4
cell types or tissue types. List the 4
types and their distinguishing
characteristics.
2.List the 4 modes of heat exchange
and provide an example of one of
those modes.
3.What is the difference between an
organ and a tissue?
A Taxonomy of Cognitive Skills for Developing Student Assignments and Assessments*
*SC SDE (Pat Mohr). Adapted from Lorin W. Anderson, David R. Krathwohl et al (Eds.) A Taxonomy for Learning, Teaching, and Assessing: A Revision
of Bloom’s Taxonomy of Educational Objectives  2001; modified by Ellen Goldey, Wofford College, to incorporate “Biology in Bloom,” Crowe et al.,
2008, CBE – Life Sci Edu., 7: 368-381.
**HOCS = higher order cognitive skills, LOCS = lower order cognitive skills.
Cognitive
Domain (Revised
Bloom)
1.Remember
(LOCS)**
2. Understand
(LOCS)
3. Apply
(LOCS/HOCS)
4. Analyze
(HOCS)
5. Evaluate
(HOCS)
Description
Retrieve
relevant
knowledge
Describe meaning
Use/apply
procedures or
info in novel
context
Infer
relationships
between
components
or parts and
bigger picture
Make judgments
based on
evidence,
criteria, and
standards
Execute, predict
Verify, critique,
Differentiate,
assess merit
organize, link,
attribute, infer,
interpret,
diagnose,
compare/contrast
, conclude,
speculate
Evaluation
Analysis
Action verbs
Original Bloom’s
term
Interpret,
Recognize,
exemplify, classify,
identify, recall, summarize/
list, label
explain/describe in
own words
Comprehension
Knowledge
Application
6. Create
(HOCS)
Piece together
info to form
novel whole;
create original
product
Generate, plan,
build, produce,
design, model
Synthesis
More stuff
• Arrive early for lecture and lab
• Pay attention (no cell phones, email, Facebook,
etc. during lecture or lab)
• Take notes on what is said….don’t wait for
boardwork.
• Powerpoints usually posted AFTER lecture
• Drop by the office for a visit!
• Complete the Personal Information Sheet on the
Moodle site and submit it electronically to
Moodle.
Chapter 1 and parts of 16
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Tissues
Organs
Organ Systems
Homeostasis
Negative & positive feedback, acclimation
Two detailed examples: Thermoregulation
and Glucose Homeostasis
Genetics & Development
Cell & Molecular
200
Histology
Name an organ and verify it
has all 4 tissue types.
Figure Anatomy
01.01c
Cell types (page 1)
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Hepatocyte
Cardiac myofiber
Type II pneumocyte
Purkinje fiber (heart)
Erythrocyte
Enteroendocrine cell
Simple cuboidal cell of
the proximal renal
tubule
• Principal cell of the
thyroid gland
• Endothelial cell
• Fibroblast
• Osteocyte
• Lactotroph
• Acinar cell of pancreas
• Beta cell of Islet of
Langerhans
• Schwann cell
More cell types (page 2)
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Rod cell of the retina
Leydig cell
Hair cell of cochlea
Smooth myofiber of
arteriole
Mast cell
Unilocular adipocyte
Alpha motoneuron
Gamma motoneuron
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Retinal ganglion cell
Megakaryocyte
Satellite cell (ganglion)
Astrocyte
Dorsal root ganglion cell
Merkel cell
Myoepithelial cell of
salivary gland
• Alpha cell of the Islet of
Langerhans
Even More Cell Types ( page 3)
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Parietal cell of stomach
Chief cell of stomach
Paneth cell
Podocyte
Juxtaglomerular cell
Cell of the macula
densa
• Chromaffin cell of the
adrenal medulla
• Parafollicular cell of the
thyroid
• Cell of the collecting
duct in the kidney
• Secretory cell of the
zona glomerulosa in
adrenal cortex
• Secretory cell of the
zonal fasciculata in
adrenal cortex
The Human Body:
A Society of Cells
• Imagine you are a cell. Ask yourself:
• Which category of cell am I? (Epithelial, Connective, Nervous, or Muscle)
• What are my special characteristics and functions that distinguish me from
all other cell types? (This is what makes me unique!)
• What do I do for the person in whom I reside? What are my contributions
to the whole organism? To homeostasis?
• What do I need to survive?
• In what ways do I depend on other cells?
• What governs my actions?
• Where did I come from? How long will I live?
• What would happen to the organism if I along with all the other cells of my
type were to fail to function properly?
Answer as many of the above questions as you can and provide your sources.
Submit your essay to the Moodle Site by midnight Sunday, Sept 8.
Bring a printout to class on Monday, Sept 9th.
O2
Cell Membrane: selectively permeable
Capillaries: highly permeable except to proteins
Homeostasis:
• The relative
constancy of
the internal
environment
• Steady state vs.
equilibrium
Beggar
Thessaloniki, Greece
First section: the importance of temperture….. thermoregulation
Second second: the importance of fuel molecules …. Glucose homeostasis
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