Bio 342 Human Physiology Theme of this course: Homeostasis Aging, infection, injury, disease Disturbed homeostasis BIO 342 HUMAN PHYSIOLOGY • PHYSIOLOGY: The study of the function of cells, tissues, organs, and organ systems. • THE TEXT: Widmaier et al. 2011 (12th ed.) & 2014 (13th edition) – Chapter 2-5 review of other courses – Using your textbook – Using chapter questions from Website The Syllabus (on the course website http://webs.wofford.edu/davisgr/bio342/) and Moodle Site for Grades and Electronic Assignments • Office & cell phone numbers • E-mail (davisgr@wofford.edu) • Lecture topics by week – Text chapters in parentheses – Read in advance of lectures – Check Moodle site 3x/wk at least LABORATORIES • May shift topics due to availability of animals • One Lab Report in the form of abstracts – very concise, based on lab data – Incorporate statistics – With revision and resubmission • No separate lab tests; lab material included on lecture tests GRADING • 3 lecture tests = 60% – – – – – multiple multiple choice (choose all correct answers) Some short answer in the space provided Rarely fill in the blank Sometime create or complete graph or diagram discussion question(s) from a list • Cumulative final exam = 20% • Other work = 20% – Abstract = 10% – 1 Question Quizzes (1QQs) and other assignments = 10% Honor Code • All worked is “pledged.” • Issues of plagiarism to be handled by the Honor Court. • Work together, but submit your own work. ODDS AND ENDS • Limited use of electronics in classroom & lab – Only for class/lab-related activities • • • • • NO FOOD or DRINKS in Lab BE ON TIME, READY TO GET TO WORK DON’T ASK ABOUT LENGTH OF LAB BE READY TO START ON TIME RECORDING LECTURES BY PERMISSION WITH LIMITS Study Questions & Quizzes • Questions provided for each chapter (On the website!) • Read the book and answer the questions PRIOR to class meeting • Class time is used to deal with problematical topics and reinforce the major concepts • Be ready for 1QQs Study Questions & Quizzes • Rationale for this format: – See what Dr. Davis thinks you ought to emphasize – Writing helps to consolidate memory and recall – Greater effort results in better retention and understanding – Students are engaged learners – Able to cover more information Improve MCAT, DCAT and GRE scores Sample 1QQ Name on top edge, back side of paper Answer on blank side of paper. 1.The 200+ cell types in the human body can be classified into one of 4 cell types or tissue types. List the 4 types and their distinguishing characteristics. 2.List the 4 modes of heat exchange and provide an example of one of those modes. 3.What is the difference between an organ and a tissue? A Taxonomy of Cognitive Skills for Developing Student Assignments and Assessments* *SC SDE (Pat Mohr). Adapted from Lorin W. Anderson, David R. Krathwohl et al (Eds.) A Taxonomy for Learning, Teaching, and Assessing: A Revision of Bloom’s Taxonomy of Educational Objectives 2001; modified by Ellen Goldey, Wofford College, to incorporate “Biology in Bloom,” Crowe et al., 2008, CBE – Life Sci Edu., 7: 368-381. **HOCS = higher order cognitive skills, LOCS = lower order cognitive skills. Cognitive Domain (Revised Bloom) 1.Remember (LOCS)** 2. Understand (LOCS) 3. Apply (LOCS/HOCS) 4. Analyze (HOCS) 5. Evaluate (HOCS) Description Retrieve relevant knowledge Describe meaning Use/apply procedures or info in novel context Infer relationships between components or parts and bigger picture Make judgments based on evidence, criteria, and standards Execute, predict Verify, critique, Differentiate, assess merit organize, link, attribute, infer, interpret, diagnose, compare/contrast , conclude, speculate Evaluation Analysis Action verbs Original Bloom’s term Interpret, Recognize, exemplify, classify, identify, recall, summarize/ list, label explain/describe in own words Comprehension Knowledge Application 6. Create (HOCS) Piece together info to form novel whole; create original product Generate, plan, build, produce, design, model Synthesis More stuff • Arrive early for lecture and lab • Pay attention (no cell phones, email, Facebook, etc. during lecture or lab) • Take notes on what is said….don’t wait for boardwork. • Powerpoints usually posted AFTER lecture • Drop by the office for a visit! • Complete the Personal Information Sheet on the Moodle site and submit it electronically to Moodle. Chapter 1 and parts of 16 • • • • • • Tissues Organs Organ Systems Homeostasis Negative & positive feedback, acclimation Two detailed examples: Thermoregulation and Glucose Homeostasis Genetics & Development Cell & Molecular 200 Histology Name an organ and verify it has all 4 tissue types. Figure Anatomy 01.01c Cell types (page 1) • • • • • • • Hepatocyte Cardiac myofiber Type II pneumocyte Purkinje fiber (heart) Erythrocyte Enteroendocrine cell Simple cuboidal cell of the proximal renal tubule • Principal cell of the thyroid gland • Endothelial cell • Fibroblast • Osteocyte • Lactotroph • Acinar cell of pancreas • Beta cell of Islet of Langerhans • Schwann cell More cell types (page 2) • • • • • • • • Rod cell of the retina Leydig cell Hair cell of cochlea Smooth myofiber of arteriole Mast cell Unilocular adipocyte Alpha motoneuron Gamma motoneuron • • • • • • • Retinal ganglion cell Megakaryocyte Satellite cell (ganglion) Astrocyte Dorsal root ganglion cell Merkel cell Myoepithelial cell of salivary gland • Alpha cell of the Islet of Langerhans Even More Cell Types ( page 3) • • • • • • Parietal cell of stomach Chief cell of stomach Paneth cell Podocyte Juxtaglomerular cell Cell of the macula densa • Chromaffin cell of the adrenal medulla • Parafollicular cell of the thyroid • Cell of the collecting duct in the kidney • Secretory cell of the zona glomerulosa in adrenal cortex • Secretory cell of the zonal fasciculata in adrenal cortex The Human Body: A Society of Cells • Imagine you are a cell. Ask yourself: • Which category of cell am I? (Epithelial, Connective, Nervous, or Muscle) • What are my special characteristics and functions that distinguish me from all other cell types? (This is what makes me unique!) • What do I do for the person in whom I reside? What are my contributions to the whole organism? To homeostasis? • What do I need to survive? • In what ways do I depend on other cells? • What governs my actions? • Where did I come from? How long will I live? • What would happen to the organism if I along with all the other cells of my type were to fail to function properly? Answer as many of the above questions as you can and provide your sources. Submit your essay to the Moodle Site by midnight Sunday, Sept 8. Bring a printout to class on Monday, Sept 9th. O2 Cell Membrane: selectively permeable Capillaries: highly permeable except to proteins Homeostasis: • The relative constancy of the internal environment • Steady state vs. equilibrium Beggar Thessaloniki, Greece First section: the importance of temperture….. thermoregulation Second second: the importance of fuel molecules …. Glucose homeostasis