Appendix A 1. How long have you been a practicing Gastroenterologist? (a) less than 5 years (b) 5 - 10 years (c) 11 - 20 years (d) more than 20 years 2. In what type of hospital do you take care of admitted IBD patients? (a) Community Hospital (b) Academic Medical Center 3. Approximately what proportion of patients in your practice have IBD? (a) less than 10% (b) 10%- 25% (c) more than 25% but less than 50% (d) 50% or more 4. You are admitting a 24 year-old man to your in-patient service for a UC flare. His disease was previously controlled with oral aminosalicylates and an anti-metabolite. For the past three weeks he has had three to four bowel movements (blood seen 50% of time) daily associated with abdominal pain despite 40 mg of Prednisone daily and topical therapy. On arrival he is in no apparent distress with normal vital signs and a completely benign abdominal exam. His leukocyte count is 12,700, hemoglobin is 10.7 g/dl, and erythrocyte sedimentation rate is 9 mm/hr. He is placed on high-dose IV steroids. What type of VTE prophylaxis, if any, would you prescribe this patient? (a) Encourage early ambulation. (b) Mechanical thromboprophylaxis with intermittent pneumatic compression. (c) Sub-cutaneous low-dose unfractionated heparin or equivalent medication. (d) Either B or C is acceptable. (e) No prophylaxis is necessary. 5. A 37 year-old male with colonic CD is admitted to your service for generalized abdominal pain and bloody diarrhea that have failed to respond adequately to outpatient prednisone. He is generally ill-appearing but hemodynamically stable and afebrile. Abdominal exam reveals mild tenderness without frank peritoneal signs. Initial laboratory evaluation is significant for a leukocyte count of 13,200, hemoglobin of 8.1 g/dl, and platelet count of 90,000. Plain films of the abdomen are unremarkable. When considering VTE prophylaxis options for this patient, what factors in the patient’s history would you consider a contraindication to prescribing pharmacologic thromboprophylaxis? (a) His active rectal bleeding. (b) The patient’s low hemoglobin and platelet counts. (c) The potential need for surgical intervention. (d) All of the above are contraindications. (e) No absolute contraindication exists for this patient. 6. A 20 year-old man with UC presents to the Emergency Department with bloody diarrhea which has failed to respond to oral prednisone and aminosalicylates. He reports approximately 10 bloody bowel movements daily, tenesmus and abdominal pain. He is found to be illappearing, with a soft, non-distended, yet diffusely tender abdominal exam. Vital signs are within normal limits. His admission hemoglobin is 8.8 g/dl and his erythrocyte sedimentation rate is 85 mm/hr. The patient is hospitalized and started on intravenous hydrocortisone (100mg every 8 hours). If you were admitting this patient, what type of VTE prophylaxis would you prescribe? (a) Encouraging early ambulation. (b) Mechanical thromboprophylaxis with intermittent pneumatic compression. (c) Sub-cutaneous low-dose unfractionated heparin or equivalent medication. (d) Either B or C is acceptable. (e) No prophylaxis is necessary 7. Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is highly prevalent in hospitalized patients. What is the relative risk of VTE in patients hospitalized for an inflammatory bowel disease (IBD) flare compared with other inpatients? (a) There are currently insufficient quality data to determine the VTE risk in hospitalized IBD patients. (b) Several studies have found no significant difference in VTE risk between hospitalized IBD patients and other inpatients. (c) Several studies have demonstrated a lower risk of VTE in hospitalized IBD patients relative to other inpatients. (d) Several studies have demonstrated a higher risk of VTE in hospitalized IBD patients relative to other inpatients. 8. In 2008 the American College of Chest Physicians (ACCP) published updated evidencebased practice guidelines on the prevention of VTE. Based on this document, the recommended modality for VTE prophylaxis in hospitalized IBD patients confined to bed is: (a) Mechanical thromboprophylaxis using intermittent pneumatic compression (IPC) or graduated compression stockings (GCS). (b) Low molecular weight heparin (LMWH), low-dose unfractionated heparin (LDUH) or fondaparinux. (c) No prophylaxis since IBD patients are relatively young, sufficiently ambulatory and lack other co-morbidities. (d) Either A or B. They are likely equivalent in this patient population. 9. In the American College of Gastroenterology (ACG) Practice Guidelines, what type of VTE prophylaxis is recommended in hospitalized UC and CD patients? (a) The ACG Practice Guidelines do not currently recommend VTE prophylaxis for hospitalized UC and CD patients. (b) The ACG Practice Guidelines recommend pharmacologic VTE prophylaxis in hospitalized CD patients but do not address the issue in UC patients. (c) The ACG Practice Guidelines recommend consideration of pharmacologic VTE prophylaxis in hospitalized UC patients but do not address the issue in CD patients. (d) The ACG Practice Guidelines recommend pharmacologic VTE prophylaxis in both hospitalized CD and UC patients. 10. In your experience, what proportion of hospitalized IBD patients at your institution receive pharmacologic VTE prophylaxis? (a) less than or equal to 25% (b) More than 25% but less than 50% (c) 50% or more but less than 75% (d) 75% or more