Cell Division SOL: BIO 6 a-c Meiosis: Important Vocabulary Diploid- contains 2 sets of chromosomes (2n = 46) Example: human somatic cells Haploid- contains 1 set of chromosomes (n = 23) Example: human gametes Meiosis: Important Vocabulary Fertilization- fusion of two haploid gametes forms a diploid zygote Zygote- fertilized egg cell The first cell of a new individual What would happen if gametes were diploid? Meiosis Meiosis occurs in sexual reproduction when a diploid germ cell produces four haploid daughter cells that can mature to become gametes (sperm or egg). Meiosis Goal: reduce genetic material by half Why? n (mom) + n (dad) = 2n (offspring) from mom from dad child too much! meiosis reduces genetic content Just right! Meiosis: cell division in two parts Sister chromatids separate Chromatids separate Meiosis I (reduction division) Meiosis II (equational division) Diploid 2n Diploid 2n Haploid n Result: one copy of each chromosome in a gamete. Meiosis I : the reduction division Spindle fibers Nucleus Nuclear envelope Prophase I (early) (diploid) Prophase I (late) (diploid) Metaphase I (diploid) Anaphase I (diploid) Telophase I (diploid) Prophase I Early prophase Late prophase Chromatids pair. Crossing over occurs. Chromosomes condense. Spindle forms. Nuclear envelope fragments. Metaphase I Chromatid pairs align along the equator of the cell. Anaphase I Chromosomes separate and move to opposite poles. Sister chromatids remain Attached at their centromeres. Telophase I Nuclear envelopes reassemble. Spindle disappears. Cytokinesis divides cell into two. Meiosis II Gene X Sister chromatids carry identical genetic information. Meiosis II produces gametes with one copy of each chromosome and thus one copy of each gene. Meiosis II : the equational division Prophase II (diploid) Metaphase II Anaphase II Telophase II Four Non-identical haploid daughter cells Prophase II Nuclear envelope fragments. Spindle forms. Metaphase II Chromosomes align along equator of cell. Anaphase II Sister chromatids separate and move to opposite poles. Telophase II Nuclear envelope assembles. Chromosomes unravel. Spindle disappears. Cytokinesis divides cell into two. Results of meiosis • Four haploid cells • One copy of each chromosome “Putting It All Together” - Fertilization What Meiosis is About Meiosis allows the creation of unique individuals through sexual reproduction. Mitosis Meiosis Number of divisions 1 2 Number of daughter cells 2 4 Yes No Same as parent (2n) Half of parent (n) Where Somatic cells Sex cells in testes and ovaries When Throughout life At sexual maturity Growth and repair Make gametes (sperm, egg, pollen) Genetically identical? Chromosome # Role MITOSIS MEIOSIS Occurs in somatic (body) cells Occurs only in gonads (sex organs: ovary/testes) Produces cells for repair, maintenance, growth, asexual reproduction Only produces gametes (sex cells: egg/sperm) Results in identical diploid (2n) daughter Reduction division results in 4 haploid cells (n) sex cells