Mendelian Genetics Curriculum Specifics Click here for all Resources Specific to the Mendelian Genetics Curriculum: 9 Days RED INDICATES HONORS EXTENSIONS ONLY Enduring understanding: Mendel’s Principles are based on probability and apply to all organisms Essential Questions (1 day) SC.912.L.16.1 Use Mendel's laws of segregation and independent assortment to analyze patterns of inheritance. What is meant by Mendel’s Law of Segregation? What is the Principle of Independent Assortment? How did Gregor Mendel contribute to modern understanding of genetics? Explain why alleles separate from one another during gamete formation. Explain why genes for different traits can separate independently from one another during the gamete formation. Analyze Gregor Mendel’s contribution to genetics. Enduring Understanding: The various models of inheritance can be caused by dominant, recessive, or codominant alleles. There are polygenic traits, and some traits are caused by multiple alleles. Some traits are sex-linked. Essential Questions (2 days) What is the Principle of Dominance? How does Law of Dominance to account for the variation that occurs during gamete formation? What are sex-linked genes and some examples? Why sex-linked genes are more commonly expressed in males and more frequently carried by females? What are some exceptions to Mendel’s principles to include incomplete dominance, codominance, polygenic, and multiple alleles? SC.912.L.16.2 Discuss observed inheritance patterns caused by various modes of inheritance, including dominant, recessive, codominant, sex-linked, polygenic, and multiple alleles. Recognize traits as being homozygous and heterozygous. Compare the difference between a genotype and a phenotype. Recognize the Principle of Dominance. Identify sex-linked traits, and explain why they are more frequent in males than in females. Identify and describe other patterns of inheritance to include incomplete dominance, codominance, multiple alleles, polygenic traits, sex-linked, epitasis, sex determination, and dosage compensation. Enduring understanding: Variations occur among all organisms. These variations originate from mutations and gene shuffling that occurs during meiosis. Essential Questions (2 days) What is a mutation and what are the ways in which they occur? What are the different kinds of mutations? How do mutations and the gene shuffling during gamete formation affect genetic variation SC.912.L.15.15 Describe how mutation and genetic recombination increase genetic variation. Explain what a mutation is. Describe different types of mutations and how they occur. Recognize that mutations and gene shuffling are the ultimate sources of mutations. Enduring Understanding: Many diseases are caused by genetic factors can have an influence on a person’s health. The factors are passed from one generation to the next HE.912.C.1.4 Analyze how heredity and family history can impact personal health. Essential Questions (2 days) How are inherited diseases passed down from one generation to the next? How can information from a pedigree chart be used to infer a person’s genotype? Use Punnett Square to predict the probabilities of genetic outcomes. Recognize that a person can be heterozygous for a trait and not express it. Compare the difference between a genotype and a phenotype. Construct and read a pedigree chart. Enduring Understanding: Diseases and problems caused by genetic factors, environmental factors, and pathogens can have significant impacts on individuals as well as public health system Essential Questions (2 days) How can environmental factors influence the expression of genetic traits? How can diseases be caused by pathogens, inheritance, or environmental factors? What affects can diseases have on our public health system? SC.912.L.14.6 Explain the significance of genetic factors, environmental factors, and pathogenic agents to health from the perspectives of both individual and public health. Define what a disease is. Describe environmental factors influencing gene expression. Describe and analyze how diseases can be caused by pathogens, the environment, or genetic factors. Analyze how the public health system helps in the control and treatment of diseases. Discuss how the environment can affect genetic outcomes in terms of public health.