Genetics Unit Plan Lesson Plan#1 - Mendelian Inheritance Blogging – blogger.com Introduction: Gregor Mendel is considered the father of genetics. An interesting part of his story is his adherence to the scientific process. As a botanist and a scientist Mendel was said to keep detailed records, strictly follow his experimental procedures and repeat his work. Mendel’s contribution is thus a combination of basic genetic principles and a model of the scientific method. Goals: LS3 (9-11) -7, LS3 (9-11)-6 Be able to identify the basic principles of heredity. Describe Mendel’s procedure and principles. Write a letter and post to the class blog. Pre-Activities: Prior to introducing Mendel’s history, students will learn about blogging and Internet safety. Students will have practiced creating posts, and commenting on other posts. Key terms: true-breeding self-pollination cross-pollination allele hybrid F1 F2 dominant recessive phenotype genotype segregation independent assortment Writing Assignments: Students will write a letter to Gregor Mendel and post this letter to the class blog. The letter will include 1. 2. 3. 4. history of genetics overview of DNA (remember that Mendel did not know about DNA) present day applications of modern genetics student will inform Herr Mendel of his impact on the biological sciences and thank him Extension and Adaptation: Students could include hyperlink to some digital resources about Mendel and/or molecular mechanics. This assignment could easily be adapted to any number of historical scientists such as Anton von Leeuwenhoek, James Watson and Francis Crick, Rosalind Franklin, Barbara McClintock, Henrietta Lacks, Stephen Jay Gould… Assessment: Rubric 3 pts for presentation, and mechanics 3 pts for each of the four components, must be accurate and readable 2 pts for creativity 2 pts for commenting on a classmates post Lesson Plan #2 – Pedigrees & Punnett Squares Online drawing tool – drawanywhere.com Introduction: After learning about Mendel’s contributions students will be introduced to the experimental protocols for his work. To best analyze Mendel’s outcomes students will learn to create Punnett squares. To apply this knowledge students will survey friends and family for some simple human genetic traits that follow the Mendelian pattern of inheritance. The research gathered will be displayed in a pedigree chart that will be created using the Web 2.0 tool drawanywhere.com. Students will then apply this to consider possible genotypic and phenotypic outcomes using Punnett squares. Goals: LS3 (9-11) -7 7b investigating how the sorting and recombination of genes in sexual reproduction results in a great variety of possible gene combinations in the offspring of any two parents. (e.g. manipulate models to represent and predict genotypes and phenotypes, Punnett Squares, probability activities). Research and create human pedigree using web based drawing tool. Create a Punnett square and calculate the phenotypic and genotypic outcomes of a di-hybrid cross. Explain how probability applies to genetics. Pre-Activities: Students will need to learn the vocabulary for this unit. Students will be encouraged to use quizlet.com for vocab review. Key terms: heredity genes traits autosome sex-linked gene homozygous heterozygous codominance incomplete dominance Writing Assignments: Students will create a pedigree chart tracing a human trait (attached ear lobes, tongue rolling, widow’s peak) and employ standard pedigree symbols to indicate relationships. Students will be quizzed both on the vocabulary and on Punnett square practices problems. Extension and Adaptation: The obvious extension is to permit people to research other families or even celebrities or fictional families. This eliminates any pressure on students from small families, foster families or step families. Assessment: Rubric for human pedigree project and 2 quizzes. Pedigree Score Sheet __________(4) (Poster Board) Format __________(4) Title with delineated generations __________(4) Neatness (straight edge format) __________(8) Symbols (male, female, heterozygotes, carriers and inflicted) __________(8) Key __________(12) Genotypes and Phenotypes __________(40) TOTAL Lesson Plan #3 – Mitosis & Meiosis Video – PowerPoint, animoto.com, screentoaster.com Introduction: Mitosis v. Meiosis. Of the five characteristics of all living things, cell division falls under the umbrella of growth/development and reproduction for some unicellular organisms. The process of mitosis and its focus on the accurate division of the genetic material sets the stage for the study of DNA and its role in the cell. Goals: LS3 (9-11) -7, W–10–6, OC-10-2 7aa distinguishing the stages of mitosis and meiosis and how each contributes to the production of offspring with varying traits Students will know why cells need to divide, the overall cell cycle and the various phases of cell division. Sequence the steps of cell division. Compare and contrast meiosis and mitosis. Create an animation model of the two processes. Pre-Activities: Students will need to understand the mechanics of molecular biology. Key vocabulary: cell division cell cycle mitosis meiosis crossing-over gamete prophase metaphase anaphase telophase chromatid centriole spindle cytokinesis centromere haploid diploid Writing Assignments: Students will write the narration to their animations of the mitosis and meiosis processes. They will focus on the genetic material and use all appropriate vocabulary. Extension and Adaptation: The goal will be to display these processes as chronologies. Students will choose a presentation style to model mitosis and meiosis. Some options include clay-mation of various stages or a video of the processes. The steps will be narrated to explain what is happening to the chromosomes throughout the phases of the cell cycle. Assessment: Rubric Meiosis/Mitosis Animation 4 # of phases accuracy of drawings/cells neatness/readability details of phase narration 3 2 1 Lesson Plan #4 - Human Genetic Disorder Research Word processing software, library databases, google documents Introduction: This 10th grade portfolio task requires that students research a human genetic disorder and prepare a paper about the symptoms, treatments and genetics behind the affliction. The process will allow them to put into practice information literacy skills such as selecting, evaluating, organizing information in an ethical way. Goals: LS3 (9-11) -7 NOS -6, R–10–15, W–10–6, Research and complete source map outline on specific human genetic disorder. Share resources and map progress using class wiki page Access CHS Library Catalog o Books – local and RICAT o Web Express o Write research paper Pre-Activities: This will serve as the culmination of the previous 3 lessons. In addition, students will need to learn about the class wiki and how to post discussion questions and research sources that they have found to be valuable. Writing Assignments: Complete and share the Source Map Outline and write research paper. The process will include using a Website Evaluation checklist if a commercial site is chosen for research. They will also share their individual research progress on a page they have created for their disorder. Extension and Adaptation: Students can choose their own human genetic disorder topic and will be encouraged to contact a support group for families and individuals that have direct contact with their chosen genetic disorder. Assessment: Research paper rubric (departmental) Lesson Plan #5 – Human Genetic Disorder Presentations Presentation software or application – PowerPoint, Prezi.com Introduction: Students will be the true experts on this topic and they will be the only ones in the class that have studied the details about this particular genetic disorder. Their presentations will be a way to formally share their information with the class and they will be expected to answer questions from their peers regarding the human genetic disorder investigated. Goals: LS3 (9-11) -7, R–10–15, W–10–6, OC-10-2 Create visual digital presentation using a Web 2.0 tool or computer software Present research to audience of peers Answer questions about details of human genetic disorder Create Work Cited page for all sources used Writing Assignments: The written part will be the works cited page in the MLA format for the presentation. Students will need to include not just research sources but any video clips, testimonials and images included in the presentation. Extension and Adaptation: The oral presentation can be pre-recorded as a video presentation. Students can choose the format for their presentation. Assessment: Rubric for both research paper and oral presentation. (departmental)