Supp. Table S9. The enriched functional terms of 43 EC-implicated
genes with 100 or more positively co-expressed lncRNAs.
Name
Pathways in cancer
nucleoplasm
cell cycle
regulation of cell cycle
chromosome organization
apoptotic process
programmed cell death
single-organism organelle organization
regulation of intracellular signal transduction
positive regulation of signaling
response to abiotic stimulus
regulation of apoptotic process
regulation of programmed cell death
regulation of organelle organization
regulation of cell death
cell proliferation
positive regulation of signal transduction
negative regulation of cell death
cellular response to stress
response to UV
Integrated Breast Cancer Pathway
p53 pathway feedback loops 2
positive regulation of cell communication
cell cycle process
positive regulation of response to stimulus
Signaling Pathways in Glioblastoma
regulation of cell proliferation
chromosome
positive regulation of protein metabolic process
regulation of chromosome organization
regulation of protein modification process
regulation of developmental process
Integrated Pancreatic Cancer Pathway
negative regulation of macromolecule metabolic
process
q-value FDR B&H
1.23E-10
1.97E-10
1.83E-09
2.71E-09
2.71E-09
4.56E-09
4.85E-09
7.28E-09
9.30E-09
1.14E-08
1.14E-08
1.14E-08
1.27E-08
1.30E-08
2.62E-08
2.62E-08
2.62E-08
2.62E-08
2.62E-08
3.35E-08
4.90E-08
5.42E-08
5.85E-08
5.85E-08
6.09E-08
7.00E-08
1.04E-07
1.12E-07
1.27E-07
1.32E-07
1.46E-07
1.56E-07
1.90E-07
1.92E-07
phosphorylation
Colorectal cancer
Cell cycle
response to radiation
cellular response to DNA damage stimulus
Prostate Cancer
2.30E-07
2.81E-07
2.86E-07
3.83E-07
3.95E-07
4.26E-07
regulation of cellular protein metabolic process
negative regulation of apoptotic process
positive regulation of intracellular signal transduction
4.89E-07
5.33E-07
5.52E-07
negative regulation of programmed cell death
negative regulation of metabolic process
Scrib-APC-beta-catenin complex
regulation of cell cycle process
regulation of DNA metabolic process
negative regulation of cellular metabolic process
Cell cycle
cell development
negative regulation of nucleobase-containing
compound metabolic process
6.19E-07
6.47E-07
8.48E-07
8.82E-07
9.15E-07
1.05E-06
1.06E-06
1.25E-06
1.25E-06
regulation of mitotic cell cycle
cytoskeleton organization
negative regulation of nitrogen compound metabolic
process
generation of neurons
positive regulation of cellular protein metabolic process
1.42E-06
1.51E-06
1.52E-06
cellular response to oxygen-containing compound
Cell Cycle: G2/M Checkpoint
enzyme binding
structure-specific DNA binding
negative regulation of DNA metabolic process
Familial cancer of breast
BREAST CANCER
response to light stimulus
neurogenesis
neuron differentiation
positive regulation of developmental process
PI3/4_kinase_CS
PI3Kc
PI3/4_kinase_cat
PI3_4_KINASE_3
PI3_4_KINASE_1
PI3_4_KINASE_2
PI3/4_kinase_cat
PI3_PI4_kinase
p53 pathway
MicroRNAs in cancer
signal transduction by p53 class mediator
cell cycle checkpoint
peptidyl-amino acid modification
regulation of cellular component organization
1.53E-06
1.69E-06
1.80E-06
1.80E-06
2.06E-06
2.35E-06
2.35E-06
2.54E-06
3.04E-06
3.47E-06
4.16E-06
4.17E-06
4.17E-06
4.17E-06
4.17E-06
4.17E-06
4.17E-06
4.17E-06
4.17E-06
4.19E-06
4.58E-06
4.79E-06
4.79E-06
5.38E-06
5.45E-06
1.53E-06
1.53E-06
mitotic cell cycle phase transition
response to oxygen-containing compound
negative regulation of cell cycle
meiotic cell cycle process
positive regulation of gene expression
cell cycle phase transition
negative regulation of cell cycle process
hematopoietic or lymphoid organ development
mitotic cell cycle checkpoint
nucleolus
chromosomal part
chromosome, telomeric region
chromosomal region
nuclear chromosome
nuclear chromosome, telomeric region
cellular response to nitrogen compound
macromolecular complex assembly
RNA polymerase II transcription factor binding
protein complex assembly
positive regulation of cell differentiation
protein complex biogenesis
Integrated Cancer pathway
response to nitrogen compound
immune system development
cellular response to organic substance
positive regulation of molecular function
regulation of cell differentiation
DNA metabolic process
regulation of DNA replication
glial cell proliferation
transferase complex
negative regulation of nuclear division
positive regulation of nucleobase-containing compound
metabolic process
5.45E-06
5.45E-06
5.50E-06
5.59E-06
6.09E-06
6.09E-06
6.49E-06
6.49E-06
6.59E-06
7.27E-06
7.27E-06
7.27E-06
7.27E-06
7.30E-06
7.30E-06
7.68E-06
7.73E-06
8.88E-06
9.56E-06
9.56E-06
9.56E-06
9.64E-06
9.90E-06
9.90E-06
9.93E-06
9.93E-06
1.00E-05
1.02E-05
1.17E-05
1.17E-05
1.18E-05
1.27E-05
1.39E-05
negative regulation of mitotic cell cycle phase transition
1.41E-05
positive regulation of protein modification process
1.60E-05
negative regulation of cell cycle phase transition
transmembrane receptor protein tyrosine kinase
signaling pathway
1.62E-05
1.73E-05
positive regulation of nitrogen compound metabolic
process
1.79E-05
cardiovascular system development
circulatory system development
nuclear chromosome part
1.91E-05
1.91E-05
1.96E-05
cellular response to peptide hormone stimulus
p53 pathway
telomere maintenance
negative regulation of cellular macromolecule
biosynthetic process
telomere organization
Ovarian Neoplasms
Carcinoma, Hepatocellular
mitotic cell cycle
regulation of protein deacetylation
hemopoiesis
cellular response to peptide
colorectal cancer
Delta-Notch Signaling Pathway
Viral carcinogenesis
Progesterone-mediated oocyte maturation
Prostate cancer
nucleoplasm part
catalytic complex
DNA damage response (only ATM dependent)
Trefoil Factors Initiate Mucosal Healing
cellular response to abiotic stimulus
negative regulation of macromolecule biosynthetic
process
Angiogenesis
regulation of cytoskeleton organization
meiosis I
Carcinoma, Squamous Cell
negative regulation of cellular component organization
1.98E-05
2.14E-05
2.15E-05
2.25E-05
Endometrial cancer
histone modification
regulation of cell division
positive regulation of cell proliferation
MAPK cascade
response to UV-C
microtubule cytoskeleton organization
covalent chromatin modification
negative regulation of DNA replication
Hypoxia and p53 in the Cardiovascular system
developmental process involved in reproduction
negative regulation of cellular biosynthetic process
4.17E-05
4.29E-05
4.29E-05
4.43E-05
4.52E-05
4.52E-05
4.52E-05
4.55E-05
4.55E-05
4.56E-05
4.95E-05
5.06E-05
ErbB signaling pathway
COLORECTAL CANCER; CRC
positive regulation of neurogenesis
5.10E-05
5.19E-05
5.53E-05
2.25E-05
2.28E-05
2.28E-05
2.33E-05
2.33E-05
2.33E-05
2.35E-05
2.55E-05
2.77E-05
2.77E-05
2.77E-05
3.21E-05
3.23E-05
3.39E-05
3.48E-05
3.54E-05
3.55E-05
3.55E-05
3.65E-05
3.67E-05
3.86E-05
4.03E-05
4.13E-05
regulation of mitotic cell cycle phase transition
positive regulation of macromolecule biosynthetic
process
enzyme linked receptor protein signaling pathway
protein complex binding
oocyte development
negative regulation of biosynthetic process
multicellular organism growth
cellular component morphogenesis
Lung Neoplasms
intrinsic apoptotic signaling pathway
central nervous system development
regulation of cell cycle phase transition
regulation of phosphorylation
protein modification by small protein conjugation
chromosome segregation
protein phosphorylation
signal transduction by protein phosphorylation
mitotic spindle assembly checkpoint
positive regulation of mitotic cell cycle
regulation of multicellular organismal development
5.54E-05
5.54E-05
chromatin modification
oocyte differentiation
spindle assembly checkpoint
negative regulation of mitotic metaphase/anaphase
transition
protein-DNA complex
macromolecule catabolic process
reproductive process
negative regulation of metaphase/anaphase transition
of cell cycle
6.46E-05
6.61E-05
6.61E-05
6.61E-05
innate immune response
cell migration
embryo development
positive regulation of microtubule polymerization
positive regulation of RNA metabolic process
MEDULLOBLASTOMA; MDB
microtubule-based process
mitotic spindle checkpoint
anatomical structure homeostasis
macromolecular complex subunit organization
blood vessel development
Adenoma
HEPATOCELLULAR CARCINOMA
Hepatocellular carcinoma
7.12E-05
7.13E-05
7.21E-05
7.46E-05
7.46E-05
7.82E-05
7.84E-05
7.98E-05
8.37E-05
8.43E-05
8.43E-05
8.51E-05
8.51E-05
8.51E-05
5.54E-05
5.72E-05
5.78E-05
5.80E-05
6.18E-05
6.18E-05
6.21E-05
6.23E-05
6.24E-05
6.26E-05
6.26E-05
6.26E-05
6.26E-05
6.27E-05
6.27E-05
6.27E-05
6.27E-05
6.33E-05
6.66E-05
6.73E-05
6.85E-05
7.07E-05
DNA Repair
protein kinase binding
organ morphogenesis
positive regulation of cellular biosynthetic process
DNA damage response, signal transduction by p53 class
mediator
response to peptide hormone
phosphatidylinositol-3-phosphate biosynthetic process
9.59E-05
9.62E-05
9.83E-05
1.01E-04
1.04E-04
regulation of telomere maintenance
meiotic cell cycle
HTLV-I infection
Pancreatic cancer
Renal cell carcinoma
Regulation of Telomerase
regulation of mitotic metaphase/anaphase transition
1.05E-04
1.06E-04
1.06E-04
1.06E-04
1.06E-04
1.06E-04
1.11E-04
peptidyl-lysine modification
single organism reproductive process
protein complex subunit organization
Breast Neoplasms
transcription factor complex
microtubule cytoskeleton
metaphase/anaphase transition of mitotic cell cycle
1.13E-04
1.13E-04
1.13E-04
1.14E-04
1.15E-04
1.15E-04
1.15E-04
regulation of metaphase/anaphase transition of cell
cycle
vasculature development
positive regulation of biosynthetic process
metaphase/anaphase transition of cell cycle
response to organonitrogen compound
negative regulation of mitotic nuclear division
protein modification by small protein conjugation or
removal
1.15E-04
positive regulation of catalytic activity
positive regulation of organelle organization
response to peptide
cell morphogenesis
reproductive structure development
1-phosphatidylinositol-3-kinase activity
phosphatidylinositol-mediated signaling
apoptotic signaling pathway
inositol lipid-mediated signaling
localization of cell
cell motility
leukocyte differentiation
1.30E-04
1.30E-04
1.30E-04
1.35E-04
1.35E-04
1.36E-04
1.36E-04
1.36E-04
1.36E-04
1.36E-04
1.36E-04
1.37E-04
1.05E-04
1.05E-04
1.15E-04
1.17E-04
1.22E-04
1.26E-04
1.29E-04
1.29E-04
reproductive system development
spindle checkpoint
ErbB4 signaling events
CDC42 signaling events
Signaling events mediated by Hepatocyte Growth
Factor Receptor (c-Met)
Signaling of Hepatocyte Growth Factor Receptor
signal transduction in response to DNA damage
gliogenesis
Chronic myeloid leukemia
positive regulation of microtubule polymerization or
depolymerization
cellular response to organonitrogen compound
cellular response to radiation
Urinary Bladder Neoplasms
GASTRIC CANCER
Wilms Tumor
mitotic cell cycle process
negative regulation of cell proliferation
kinase binding
Cellular responses to stress
regulation of phosphate metabolic process
response to ionizing radiation
positive regulation of cell death
positive regulation of phosphorylation
ARM-type_fold
regulation of immune system process
regulation of phosphorus metabolic process
neuron development
anatomical structure formation involved in
morphogenesis
1.37E-04
1.37E-04
1.40E-04
1.43E-04
1.45E-04
homeostatic process
brain development
protein ubiquitination
positive regulation of transcription, DNA-templated
1.79E-04
1.81E-04
1.81E-04
1.86E-04
positive regulation of cell development
double-strand break repair
epidermal growth factor receptor signaling pathway
1.90E-04
1.92E-04
1.93E-04
positive regulation of determination of dorsal identity
1.94E-04
telomere maintenance via telomere shortening
nucleotide-excision repair, DNA incision, 3'-to lesion
1.94E-04
1.94E-04
blood vessel morphogenesis
2.08E-04
1.45E-04
1.47E-04
1.47E-04
1.50E-04
1.52E-04
1.54E-04
1.62E-04
1.62E-04
1.62E-04
1.62E-04
1.66E-04
1.66E-04
1.68E-04
1.68E-04
1.68E-04
1.71E-04
1.73E-04
1.73E-04
1.75E-04
1.78E-04
1.78E-04
1.79E-04
1.79E-04
ERBB signaling pathway
Signaling of Hepatocyte Growth Factor Receptor
Medulloblastoma
regulation of protein stability
protein deacetylation
chromatin organization
Fc receptor signaling pathway
protein kinase B signaling
aging
cellular macromolecule catabolic process
positive regulation of RNA biosynthetic process
Glucocorticoid receptor regulatory network
FOXM1 transcription factor network
Apoptotic cleavage of cellular proteins
protein deacylation
peroxisome proliferator activated receptor binding
2.12E-04
2.13E-04
2.13E-04
2.14E-04
2.23E-04
2.23E-04
2.23E-04
2.32E-04
2.32E-04
2.40E-04
2.40E-04
2.44E-04
2.44E-04
2.44E-04
2.56E-04
2.57E-04
Neoplasms
Regulation of Actin Cytoskeleton
negative regulation of organelle organization
neuron projection development
oogenesis
regulation of proteolysis
DNA damage checkpoint
ErbB signaling pathway
Androgen receptor signaling pathway
regulation of nuclear division
lamellipodium
microtubule organizing center
cellular response to hormone stimulus
regulation of microtubule polymerization
TWEAK Signaling Pathway
nuclear division
response to hypoxia
N-terminal peptidyl-lysine acetylation
fungiform papilla morphogenesis
fungiform papilla formation
negative regulation of developmental process
positive regulation of phosphorus metabolic process
2.66E-04
2.78E-04
2.86E-04
2.93E-04
2.97E-04
2.99E-04
2.99E-04
3.06E-04
3.06E-04
3.07E-04
3.13E-04
3.19E-04
3.20E-04
3.29E-04
3.29E-04
3.35E-04
3.41E-04
3.46E-04
3.46E-04
3.46E-04
3.51E-04
3.53E-04
positive regulation of phosphate metabolic process
3.53E-04
response to X-ray
response to lipid
response to decreased oxygen levels
epithelium development
3.55E-04
3.56E-04
3.56E-04
3.59E-04
DNA integrity checkpoint
multi-organism cellular process
Carcinoma, Adenoid Cystic
Multi-step Regulation of Transcription by Pitx2
spindle
regulation of DNA damage response, signal
transduction by p53 class mediator
cellular component disassembly involved in execution
phase of apoptosis
regulation of cellular response to stress
regulation of gliogenesis
phosphatidylinositol 3-kinase activity
double-stranded DNA binding
transcription factor binding
FoxO family signaling
response to oxygen levels
cell aging
organelle fission
regulation of protein processing
neurotrophin TRK receptor signaling pathway
positive regulation of cellular component organization
3.67E-04
3.74E-04
3.82E-04
3.84E-04
3.85E-04
3.86E-04
growth
regulation of MAPK cascade
response to drug
neurotrophin signaling pathway
NOTCH1 Intracellular Domain Regulates Transcription
4.75E-04
4.75E-04
4.78E-04
4.78E-04
4.79E-04
gland development
regulation of oligodendrocyte differentiation
positive regulation of proteolysis
fungiform papilla development
regulation of determination of dorsal identity
Aberrant Crypt Foci
regulation of anatomical structure morphogenesis
microtubule polymerization
phosphatidylinositol kinase activity
DNA repair
G2/M transition of mitotic cell cycle
peptidyl-serine phosphorylation
regulation of DNA-dependent DNA replication
hair follicle development
molting cycle process
hair cycle process
cell division
cell cycle G2/M phase transition
4.96E-04
4.96E-04
5.04E-04
5.12E-04
5.12E-04
5.26E-04
5.29E-04
5.36E-04
5.36E-04
5.44E-04
5.66E-04
5.75E-04
5.75E-04
5.75E-04
5.75E-04
5.75E-04
5.81E-04
5.81E-04
4.06E-04
4.22E-04
4.22E-04
4.35E-04
4.35E-04
4.35E-04
4.50E-04
4.58E-04
4.58E-04
4.58E-04
4.58E-04
4.58E-04
4.58E-04
positive regulation of apoptotic process
immune response
insulin receptor signaling pathway
Fc-epsilon receptor signaling pathway
phosphatidylinositol phosphorylation
regulation of chromosome segregation
response to endogenous stimulus
IL-3 Signaling Pathway
Telomeres, Telomerase, Cellular Aging, and Immortality
5.90E-04
5.92E-04
6.03E-04
6.03E-04
6.09E-04
6.09E-04
6.14E-04
6.15E-04
6.15E-04
PTEN dependent cell cycle arrest and apoptosis
cell projection organization
positive regulation of programmed cell death
lymphocyte differentiation
fibroblast growth factor receptor signaling pathway
6.15E-04
6.29E-04
6.30E-04
6.30E-04
6.50E-04
gamete generation
Apoptotic execution phase
meiotic nuclear division
mitotic DNA damage checkpoint
canonical Wnt signaling pathway involved in negative
regulation of apoptotic process
hair follicle placode formation
regulation of response to stress
reproduction
peptidyl-serine modification
DNA replication
positive regulation of cell migration
movement of cell or subcellular component
sister chromatid cohesion
posttranscriptional regulation of gene expression
positive regulation of protein processing
regulation of protein phosphorylation
mitotic DNA integrity checkpoint
single-stranded DNA binding
positive regulation of cell motility
DNA repair complex
lung development
ATM Signaling Pathway
Constitutive Signaling by NOTCH1 HD+PEST Domain
Mutants
6.56E-04
6.56E-04
6.62E-04
6.66E-04
6.93E-04
VEGF signaling pathway
HIV-I Nef: negative effector of Fas and TNF
Notch signaling pathway
Constitutive Signaling by NOTCH1 PEST Domain
Mutants
8.15E-04
8.15E-04
8.15E-04
8.15E-04
6.93E-04
7.02E-04
7.11E-04
7.16E-04
7.24E-04
7.24E-04
7.40E-04
7.40E-04
7.47E-04
7.50E-04
7.64E-04
7.74E-04
7.75E-04
7.84E-04
7.89E-04
7.99E-04
8.15E-04
8.15E-04
Mechanism of Gene Regulation by Peroxisome
Proliferators via PPARa(alpha)
Wnt Signaling Pathway NetPath
Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility
8.15E-04
protein catabolic process
lipid phosphorylation
heart development
respiratory tube development
cytoskeletal part
cytoskeleton
positive regulation of cellular component movement
8.40E-04
8.44E-04
8.64E-04
8.65E-04
8.65E-04
8.72E-04
8.91E-04
cell morphogenesis involved in neuron differentiation
8.91E-04
reciprocal DNA recombination
reciprocal meiotic recombination
muscle cell differentiation
Schwann cell proliferation
nucleotide-excision repair, DNA incision
positive regulation of protein kinase activity
Carcinoma of colon
Cecal Neoplasms
Penile Neoplasms
cellular response to fibroblast growth factor stimulus
8.93E-04
8.93E-04
8.93E-04
8.93E-04
8.93E-04
8.95E-04
9.07E-04
9.07E-04
9.07E-04
9.20E-04
chordate embryonic development
cellular response to lipid
cell morphogenesis involved in differentiation
Role of ERBB2 in Signal Transduction and Oncology
VEGF signaling pathway
neuron projection morphogenesis
Cell Cycle
positive regulation of locomotion
response to fibroblast growth factor
regulation of myeloid leukocyte differentiation
regulation of cellular component biogenesis
defense response
immune response-regulating signaling pathway
regulation of protein ubiquitination
embryo development ending in birth or egg hatching
9.24E-04
9.24E-04
9.25E-04
9.42E-04
9.42E-04
9.45E-04
9.46E-04
9.60E-04
9.60E-04
9.60E-04
9.60E-04
9.60E-04
9.69E-04
9.72E-04
9.74E-04
negative regulation of transcription from RNA
polymerase II promoter
hair cycle
molting cycle
9.74E-04
8.15E-04
8.30E-04
9.74E-04
9.74E-04
positive regulation of multicellular organismal process
9.75E-04
cellular response to growth factor stimulus
locomotion
Angiogenesis
G alpha 12 Pathway
Double-Strand Break Repair
Signaling events mediated by VEGFR1 and VEGFR2
regulation of microtubule cytoskeleton organization
9.75E-04
9.75E-04
9.90E-04
9.90E-04
9.90E-04
9.90E-04
9.96E-04
Epstein-Barr virus infection
IL-4 signaling Pathway
execution phase of apoptosis
female gamete generation
Glioma
CXCR4 Signaling Pathway
Erk and PI-3 Kinase Are Necessary for Collagen Binding
in Corneal Epithelia
Focal adhesion
myeloid cell differentiation
intrinsic apoptotic signaling pathway in response to
DNA damage
canonical Wnt signaling pathway
cellular response to UV
response to hormone
protein processing
regulation of sarcomere organization
regulation of miRNA metabolic process
regulation of telomere maintenance via telomerase
1.02E-03
1.02E-03
1.03E-03
1.03E-03
1.04E-03
1.04E-03
1.04E-03
tongue morphogenesis
positive regulation of kinase activity
odontogenesis
response to growth factor
intrinsic apoptotic signaling pathway in response to
DNA damage by p53 class mediator
1.07E-03
1.09E-03
1.09E-03
1.10E-03
1.12E-03
regulation of signal transduction by p53 class mediator
1.12E-03
double-stranded telomeric DNA binding
histone deacetylase regulator activity
Kinase-like_dom
TRAIL signaling pathway
regulation of transferase activity
germ cell development
immune response-regulating cell surface receptor
signaling pathway
1.14E-03
1.14E-03
1.15E-03
1.15E-03
1.16E-03
1.16E-03
1.17E-03
1.05E-03
1.05E-03
1.05E-03
1.07E-03
1.07E-03
1.07E-03
1.07E-03
1.07E-03
1.07E-03
1.07E-03
Developmental Biology
Ras Pathway
regulation of sequence-specific DNA binding
transcription factor activity
positive regulation of gliogenesis
positive regulation of protein phosphorylation
IL-5 Signaling Pathway
Hypoxia response via HIF activation
Fanconi Anemia pathway
respiratory system development
Direct p53 effectors
Fc epsilon RI signaling pathway
Melanoma
Phospholipids as signalling intermediaries
Granule Cell Survival Pathway is a specific case of more
general PAC1 Receptor Pathway.
1.18E-03
1.18E-03
1.18E-03
Inactivation of Gsk3 by AKT causes accumulation of bcatenin in Alveolar Macrophages
Ubiquitin mediated proteolysis
Prolactin signaling pathway
altered canonical Wnt signaling
LRR FLII-interacting protein 1 (LRRFIP1) activates type I
IFN production
Signaling by NOTCH1
Signaling by NOTCH1 in Cancer
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555)
Translocation Mutant
FBXW7 Mutants and NOTCH1 in Cancer
Signaling by NOTCH1 PEST Domain Mutants in Cancer
1.23E-03
Signaling by NOTCH1 HD Domain Mutants in Cancer
1.23E-03
Signaling by NOTCH1 HD+PEST Domain Mutants in
Cancer
1.23E-03
protein maturation
circadian regulation of gene expression
response to gamma radiation
Cell Cycle: G1/S Check Point
Proteoglycans in cancer
adherens junction
Prolactin Signaling Pathway
Thyroid cancer
BARD1 signaling events
VEGF, Hypoxia, and Angiogenesis
Colorectal Neoplasms
MISMATCH REPAIR CANCER SYNDROME
1.23E-03
1.24E-03
1.24E-03
1.24E-03
1.27E-03
1.27E-03
1.31E-03
1.31E-03
1.31E-03
1.31E-03
1.33E-03
1.33E-03
1.18E-03
1.20E-03
1.22E-03
1.22E-03
1.22E-03
1.22E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
1.23E-03
Turcot syndrome
positive regulation of cell cycle process
myelin sheath abaxonal region
cell cycle arrest
RNA polymerase II activating transcription factor
binding
MutLalpha complex binding
protein N-terminus binding
ATP binding
kinase activity
negative regulation of gene expression
regulation of mitotic nuclear division
viral process
Hepatitis B
DNA recombination
cellular response to ionizing radiation
regulation of muscle cell differentiation
cell activation
Regulation of Wnt-mediated beta catenin signaling and
target gene transcription
regulation of protein kinase activity
Signaling by ERBB4
regulation of catabolic process
histone H3-K4 trimethylation
negative regulation of telomere maintenance
regulation of epithelial cell proliferation involved in
prostate gland development
cellular response to insulin stimulus
adenyl ribonucleotide binding
1-phosphatidylinositol-4-phosphate 3-kinase activity
1.33E-03
1.33E-03
1.35E-03
1.36E-03
1.38E-03
regulation of transcription from RNA polymerase II
promoter
1.63E-03
striated muscle cell differentiation
anchoring junction
stress-activated MAPK cascade
histone H4 acetylation
positive regulation of cell cycle
Osteopontin-mediated events
adenyl nucleotide binding
Integrin Signaling Pathway
positive regulation of MAPK cascade
purine ribonucleoside triphosphate binding
mismatch repair complex binding
purine ribonucleoside binding
purine nucleoside binding
1.64E-03
1.66E-03
1.67E-03
1.68E-03
1.69E-03
1.70E-03
1.72E-03
1.73E-03
1.74E-03
1.76E-03
1.76E-03
1.76E-03
1.76E-03
1.38E-03
1.38E-03
1.38E-03
1.38E-03
1.39E-03
1.43E-03
1.44E-03
1.45E-03
1.45E-03
1.46E-03
1.46E-03
1.46E-03
1.54E-03
1.56E-03
1.56E-03
1.57E-03
1.58E-03
1.58E-03
1.58E-03
1.59E-03
1.63E-03
1.63E-03
ribonucleoside binding
regulation of protein localization
regulation of microtubule-based process
Hippo signaling pathway
nucleoside binding
stress-activated protein kinase signaling cascade
regulation of neuron death
Intracellular Signalling Through Adenosine Receptor
A2a and Adenosine
N-cadherin signaling events
N-terminal protein amino acid acetylation
replicative senescence
negative regulation of DNA-dependent DNA replication
1.76E-03
1.76E-03
1.77E-03
1.77E-03
1.79E-03
1.80E-03
1.80E-03
1.80E-03
epithelial cell proliferation involved in prostate gland
development
1.86E-03
Insulin/IGF pathway-protein kinase B signaling cascade
1.89E-03
Angiotensin II mediated activation of JNK Pathway via
Pyk2 dependent signaling
Gastric cancer network 2
Intracellular Signalling Through Adenosine Receptor
A2b and Adenosine
Genes related to CD40 signaling
axonogenesis
Neoplasm of ovary
Small cell lung cancer
purine ribonucleotide binding
regulation of protein binding
FATC
FAT
PIK-rel_kinase_FAT
FAT
FATC
PIK_FAT
FATC
negative regulation of cell differentiation
ErbB2/ErbB3 signaling events
FAS (CD95) signaling pathway
histone deacetylation
response to organic cyclic compound
ribonucleotide binding
purine nucleotide binding
phosphotransferase activity, alcohol group as acceptor
1.89E-03
positive regulation of cytoskeleton organization
2.03E-03
1.80E-03
1.86E-03
1.86E-03
1.86E-03
1.89E-03
1.89E-03
1.89E-03
1.90E-03
1.91E-03
1.92E-03
1.93E-03
1.94E-03
1.99E-03
1.99E-03
1.99E-03
1.99E-03
1.99E-03
1.99E-03
1.99E-03
1.99E-03
2.01E-03
2.01E-03
2.01E-03
2.01E-03
2.02E-03
2.02E-03
2.02E-03
Apoptosis
regulation of neurogenesis
regulation of microtubule polymerization or
depolymerization
establishment or maintenance of cell polarity
peptidyl-lysine acetylation
Adrenergic Pathway
Agrin in Postsynaptic Differentiation
UV protection
determination of dorsal identity
positive regulation of protein ubiquitination involved in
ubiquitin-dependent protein catabolic process
2.04E-03
2.04E-03
2.10E-03
determination of dorsal/ventral asymmetry
sexual reproduction
Corticotropin-releasing hormone
angiogenesis
cell-cell adherens junction
JUN kinase binding
regulation of kinase activity
negative regulation of transcription, DNA-templated
2.15E-03
2.16E-03
2.18E-03
2.20E-03
2.23E-03
2.25E-03
2.25E-03
2.26E-03
regulation of glial cell differentiation
beta-catenin destruction complex
lymphocyte activation
PI3K_ras-bd
PI3K_rbd
PI3K_rbd
axon development
muscle cell proliferation
circadian rhythm
Signaling events regulated by Ret tyrosine kinase
Bladder cancer
TSLP Signaling Pathway
Integrin Signaling Pathway
interspecies interaction between organisms
symbiosis, encompassing mutualism through parasitism
2.26E-03
2.35E-03
2.35E-03
2.37E-03
2.37E-03
2.37E-03
2.37E-03
2.39E-03
2.39E-03
2.40E-03
2.40E-03
2.40E-03
2.40E-03
2.44E-03
2.44E-03
positive regulation of DNA damage response, signal
transduction by p53 class mediator
2.45E-03
regulation of sister chromatid cohesion
determination of adult lifespan
axon
cell projection
telomere cap complex
nuclear telomere cap complex
2.45E-03
2.45E-03
2.45E-03
2.45E-03
2.45E-03
2.45E-03
2.12E-03
2.12E-03
2.13E-03
2.13E-03
2.15E-03
2.15E-03
2.15E-03
cellular process involved in reproduction in
multicellular organism
cellular response to endogenous stimulus
multicellular organismal reproductive process
regulation of osteoclast differentiation
positive regulation of transferase activity
negative regulation of RNA biosynthetic process
Fc Epsilon Receptor I Signaling in Mast Cells
Aldosterone-regulated sodium reabsorption
OVARIAN CANCER
activating transcription factor binding
positive regulation of chromosome organization
damaged DNA binding
transferase activity, transferring phosphorus-containing
groups
2.48E-03
XY body
Sin3-type complex
Sin3 complex
histone acetyltransferase activity
regulation of immune response
limb morphogenesis
appendage morphogenesis
IFN-gamma pathway
regulation of canonical Wnt signaling pathway
PI3K_C2
PI3K_C2
PI3K_C2
positive regulation of glycoprotein metabolic process
2.64E-03
2.64E-03
2.64E-03
2.65E-03
2.67E-03
2.68E-03
2.68E-03
2.73E-03
2.74E-03
2.74E-03
2.74E-03
2.74E-03
2.76E-03
positive regulation of glycoprotein biosynthetic process
2.76E-03
DNA damage response, signal transduction by p53 class
mediator resulting in cell cycle arrest
2.83E-03
response to wounding
multicellular organism reproduction
protein acetylation
signal transduction involved in mitotic G1 DNA damage
checkpoint
2.84E-03
2.90E-03
2.90E-03
2.91E-03
intracellular signal transduction involved in G1 DNA
damage checkpoint
2.91E-03
intrinsic apoptotic signaling pathway by p53 class
mediator
2.91E-03
IL-6 Signaling Pathway
Transcriptional misregulation in cancer
neuron death
proteasomal protein catabolic process
2.93E-03
2.93E-03
2.96E-03
2.96E-03
2.49E-03
2.51E-03
2.52E-03
2.52E-03
2.52E-03
2.56E-03
2.56E-03
2.57E-03
2.59E-03
2.62E-03
2.63E-03
2.63E-03
Stomach Neoplasms
Lymphoma, T-Cell, Peripheral
Colorectal Neoplasms, Hereditary Nonpolyposis
Neoplasm of stomach
signal transduction involved in mitotic cell cycle
checkpoint
signal transduction involved in DNA integrity
checkpoint
signal transduction involved in DNA damage checkpoint
2.98E-03
2.98E-03
2.98E-03
2.98E-03
2.99E-03
signal transduction involved in mitotic DNA damage
checkpoint
positive regulation of translation
signal transduction involved in mitotic DNA integrity
checkpoint
2.99E-03
tube development
cell projection morphogenesis
PInositide-3_kin_accessory_dom
PI3Ka
PI3Ka
PI3Ka
negative regulation of RNA metabolic process
ectodermal placode formation
ectodermal placode morphogenesis
miRNA metabolic process
ectodermal placode development
regulation of gene expression, epigenetic
signal transduction involved in cell cycle checkpoint
2.99E-03
2.99E-03
3.00E-03
3.00E-03
3.00E-03
3.00E-03
3.02E-03
3.02E-03
3.02E-03
3.02E-03
3.02E-03
3.05E-03
3.05E-03
G2/M DNA damage checkpoint
response to insulin
Melanogenesis
Cellular Senescence
FGF signaling pathway
Apoptosis signaling pathway
Focal Adhesion
Signalling by NGF
Interleukin-2 signaling
cellular response to hydrogen peroxide
cellular nitrogen compound catabolic process
heterocycle catabolic process
tissue development
protein oligomerization
double-strand break repair via homologous
recombination
transcription from RNA polymerase II promoter
3.08E-03
3.09E-03
3.09E-03
3.09E-03
3.15E-03
3.15E-03
3.15E-03
3.15E-03
3.15E-03
3.17E-03
3.17E-03
3.22E-03
3.23E-03
3.23E-03
3.27E-03
2.99E-03
2.99E-03
2.99E-03
2.99E-03
3.27E-03
regulation of organ morphogenesis
regulation of cellular catabolic process
cell part morphogenesis
positive regulation of signal transduction by p53 class
mediator
negative regulation of anoikis
cellular response to gamma radiation
microtubule polymerization or depolymerization
recombinational repair
regulation of nervous system development
negative regulation of neuron death
Chemokine signaling pathway
HIF-1 signaling pathway
Differentiation Pathway in PC12 Cells; this is a specific
case of PAC1 Receptor Pathway.
3.27E-03
3.30E-03
3.33E-03
3.33E-03
Activation of the AP-1 family of transcription factors
3.52E-03
RAF/MAP kinase cascade
protein kinase activity
Notch signaling pathway
protein ubiquitination involved in ubiquitin-dependent
protein catabolic process
PI_Kinase
appendage development
response to estrogen
limb development
Presenilin action in Notch and Wnt signaling
Integrins in angiogenesis
mammary gland epithelium development
positive regulation of type I interferon production
MicroRNAs in cardiomyocyte hypertrophy
Fc epsilon receptor (FCERI) signaling
TNF signaling pathway
TRIF-dependent toll-like receptor signaling pathway
3.52E-03
3.54E-03
3.57E-03
3.59E-03
H4 histone acetyltransferase activity
organic cyclic compound catabolic process
EGF receptor signaling pathway
mitotic G1/S transition checkpoint
mitotic G1 DNA damage checkpoint
Angiopoietin receptor Tie2-mediated signaling
Type II diabetes mellitus
Regulation of the Fanconi anemia pathway
regulation of glial cell proliferation
G1 DNA damage checkpoint
positive regulation of protein polymerization
3.84E-03
3.84E-03
3.93E-03
3.95E-03
3.95E-03
3.98E-03
3.98E-03
4.05E-03
4.08E-03
4.08E-03
4.08E-03
3.33E-03
3.33E-03
3.34E-03
3.34E-03
3.35E-03
3.50E-03
3.51E-03
3.51E-03
3.52E-03
3.61E-03
3.62E-03
3.62E-03
3.62E-03
3.66E-03
3.66E-03
3.69E-03
3.69E-03
3.75E-03
3.75E-03
3.82E-03
3.83E-03
protein serine/threonine kinase activity
epithelial cell proliferation
epidermis development
glial cell differentiation
MyD88-independent toll-like receptor signaling
pathway
Signaling by NOTCH
regulation of myeloid cell differentiation
Adenocarcinoma
oligodendrocyte differentiation
Regulation of Androgen receptor activity
regulation of ossification
transcription coactivator activity
phosphatidylinositol 3-kinase complex
Carcinoma, Renal Cell
telomere maintenance via telomerase
odontogenesis of dentin-containing tooth
stem cell differentiation
wound healing
telomeric DNA binding
Control of Gene Expression by Vitamin D Receptor
Meiosis
cellular response to light stimulus
IL2-mediated signaling events
regulation of protein ubiquitination involved in
ubiquitin-dependent protein catabolic process
regulation of anoikis
toll-like receptor 3 signaling pathway
nucleotide-excision repair
MAPK
MAP_kinase_CS
Neurotrophin signaling pathway
Glioblastoma
Prostatic Neoplasms
Intestinal Neoplasms
FCERI mediated MAPK activation
Fanconi anemia pathway
protein acylation
myeloid leukocyte differentiation
cell adhesion molecule binding
leukocyte activation
proteolysis involved in cellular protein catabolic process
4.10E-03
4.11E-03
4.11E-03
4.18E-03
4.20E-03
JNK cascade
positive regulation of cell cycle arrest
Toxoplasmosis
5.11E-03
5.18E-03
5.18E-03
4.23E-03
4.25E-03
4.28E-03
4.33E-03
4.40E-03
4.41E-03
4.42E-03
4.44E-03
4.45E-03
4.47E-03
4.47E-03
4.52E-03
4.57E-03
4.70E-03
4.73E-03
4.73E-03
4.77E-03
4.85E-03
4.89E-03
4.89E-03
4.89E-03
4.89E-03
4.92E-03
4.92E-03
4.97E-03
5.00E-03
5.00E-03
5.00E-03
5.03E-03
5.03E-03
5.05E-03
5.05E-03
5.05E-03
5.06E-03
5.06E-03
RANKL/RANK Signaling Pathway
NFAT and Hypertrophy of the heart (Transcription in
the broken heart)
Signaling events mediated by focal adhesion kinase
5.18E-03
5.18E-03
Oxidative Stress Induced Gene Expression Via Nrf2
Keap1-Nrf2 Pathway
RB Tumor Suppressor/Checkpoint Signaling in response
to DNA damage
Regulation of actin cytoskeleton
proteolysis
peptidyl-lysine trimethylation
DNA excision
nucleotide-excision repair, DNA damage removal
ATF-2 transcription factor network
neuron part
nuclear transcription factor complex
vasculogenesis
Regulation of retinoblastoma protein
Non-small cell lung cancer
positive regulation of transcription from RNA
polymerase II promoter
dendrite cytoplasm
cell leading edge
Axon guidance
NOD-like receptor signaling pathway
Acute myeloid leukemia
Homologous recombination
SOS-mediated signalling
Cell to Cell Adhesion Signaling
Presenilin action in Notch and Wnt signaling
GRB2 events in EGFR signaling
tongue development
positive regulation of protein acetylation
N-terminal protein amino acid modification
osteoclast differentiation
cellular protein catabolic process
cell-cell junction organization
B cell activation
GLIOMA SUSCEPTIBILITY 1; GLM1
Fc-gamma receptor signaling pathway involved in
phagocytosis
5.20E-03
5.20E-03
5.20E-03
immune response-regulating cell surface receptor
signaling pathway involved in phagocytosis
protein stabilization
epithelial tube morphogenesis
5.92E-03
5.18E-03
5.22E-03
5.25E-03
5.28E-03
5.28E-03
5.28E-03
5.31E-03
5.36E-03
5.36E-03
5.48E-03
5.53E-03
5.53E-03
5.54E-03
5.59E-03
5.59E-03
5.64E-03
5.65E-03
5.65E-03
5.65E-03
5.65E-03
5.65E-03
5.65E-03
5.65E-03
5.75E-03
5.75E-03
5.75E-03
5.79E-03
5.79E-03
5.79E-03
5.82E-03
5.83E-03
5.92E-03
5.92E-03
5.96E-03
multi-organism reproductive process
Ras protein signal transduction
Cell-Cell communication
cell junction assembly
cellular macromolecular complex assembly
Fc-gamma receptor signaling pathway
Fc-epsilon receptor I signaling in mast cells
glycoprotein biosynthetic process
Wnt signaling pathway
Hepatitis C
SHC-mediated signalling
the planar cell polarity Wnt signaling
Hypoxia-Inducible Factor in the Cardiovascular System
5.98E-03
6.01E-03
6.02E-03
6.04E-03
6.04E-03
6.04E-03
6.05E-03
6.12E-03
6.18E-03
6.20E-03
6.20E-03
6.20E-03
6.20E-03
SHC1 events in EGFR signaling
Signalling to p38 via RIT and RIN
blood coagulation
steroid hormone receptor binding
T cell differentiation
regulation of cell development
coagulation
vesicle-mediated transport
regulation of neuron apoptotic process
hemostasis
skin development
regionalization
oocyte maturation
regulation of histone deacetylation
attachment of spindle microtubules to kinetochore
6.20E-03
6.20E-03
6.24E-03
6.28E-03
6.30E-03
6.32E-03
6.38E-03
6.41E-03
6.47E-03
6.47E-03
6.47E-03
6.47E-03
6.51E-03
6.51E-03
6.51E-03
Fc receptor mediated stimulatory signaling pathway
6.61E-03
phosphatidylinositol biosynthetic process
regulation of multicellular organism growth
Genes in module_403
Signaling by SCF-KIT
Role of nicotinic acetylcholine receptors in the
regulation of apoptosis
6.61E-03
6.61E-03
6.64E-03
6.76E-03
6.76E-03
p53 Signaling Pathway
Homologous recombination repair of replicationindependent double-strand breaks
6.76E-03
6.76E-03
Homologous Recombination Repair
ARMS-mediated activation
p53 signaling pathway
Oncostatin M Signaling Pathway
NCAM signaling for neurite out-growth
6.76E-03
6.76E-03
6.76E-03
6.76E-03
6.76E-03
Wnt signaling pathway
tube morphogenesis
regulation of histone modification
anoikis
establishment or maintenance of apical/basal cell
polarity
positive regulation of collagen biosynthetic process
6.86E-03
6.94E-03
6.94E-03
6.94E-03
6.94E-03
establishment or maintenance of bipolar cell polarity
6.94E-03
RNA-dependent DNA replication
TSH signaling pathway
regulation of protein catabolic process
regulation of cell migration
protein C-terminus binding
Insulin signaling pathway
regulation of apoptotic signaling pathway
anterior/posterior pattern specification
Pancreatic Neoplasms
regulation of cysteine-type endopeptidase activity
6.94E-03
7.01E-03
7.08E-03
7.09E-03
7.11E-03
7.15E-03
7.16E-03
7.16E-03
7.25E-03
7.27E-03
Hemostasis
Human Cytomegalovirus and Map Kinase Pathways
7.29E-03
7.29E-03
PTEN is a tumor suppressor that dephosphorylates the
lipid messenger phosphatidylinositol triphosphate.
7.29E-03
Tumor Suppressor Arf Inhibits Ribosomal Biogenesis
7.29E-03
IL-7 Signal Transduction
Beta-catenin phosphorylation cascade
regulation of hydrolase activity
BCR signaling pathway
positive regulation of collagen metabolic process
regulation of odontogenesis
regulation of protein export from nucleus
BDNF signaling pathway
Downstream signaling of activated FGFR
regulation of smooth muscle cell proliferation
DNA secondary structure binding
Long-term potentiation
DNA damage response
Signaling events mediated by HDAC Class I
Genes in module_57
ossification
Cytosolic sensors of pathogen-associated DNA
7.29E-03
7.29E-03
7.31E-03
7.36E-03
7.38E-03
7.38E-03
7.38E-03
7.40E-03
7.40E-03
7.41E-03
7.47E-03
7.51E-03
7.51E-03
7.51E-03
7.53E-03
7.59E-03
7.67E-03
6.94E-03
p53 signaling pathway
SHC-related events
Nongenotropic Androgen signaling
Nerve growth factor pathway (NGF)
Frs2-mediated activation
SHC-related events triggered by IGF1R
Role of Erk5 in Neuronal Survival
regulation of Wnt signaling pathway
muscle structure development
positive regulation of sequence-specific DNA binding
transcription factor activity
negative regulation of G1/S transition of mitotic cell
cycle
7.67E-03
7.67E-03
7.67E-03
7.67E-03
7.67E-03
7.67E-03
7.67E-03
7.67E-03
7.69E-03
7.76E-03
negative regulation of cell cycle G1/S phase transition
7.76E-03
nucleobase-containing compound catabolic process
7.81E-03
transcription cofactor activity
MAP kinase activity
smooth muscle cell proliferation
cellular response to reactive oxygen species
immune response-activating signal transduction
response to steroid hormone
single-organism biosynthetic process
cellular protein localization
phosphatidylinositol phosphate kinase activity
mitogen-activated protein kinase binding
heart morphogenesis
regulation of cell cycle arrest
cellular macromolecule localization
mammary gland epithelial cell proliferation
regulation of glycolytic process
TGF beta signaling pathway
MAP00562 Inositol phosphate metabolism
Tie2 Signaling
Role of MAL in Rho-Mediated Activation of SRF
TP53 network
mitotic nuclear division
cellular response to hypoxia
Glioma
Lung cancer
LUNG CANCER
Hemangiosarcoma
Kidney Neoplasms
Nasopharyngeal carcinoma
Endometriosis
7.87E-03
7.87E-03
7.93E-03
7.93E-03
7.99E-03
7.99E-03
8.02E-03
8.07E-03
8.27E-03
8.27E-03
8.28E-03
8.28E-03
8.28E-03
8.28E-03
8.28E-03
8.36E-03
8.36E-03
8.36E-03
8.36E-03
8.36E-03
8.44E-03
8.44E-03
8.62E-03
8.62E-03
8.62E-03
8.62E-03
8.62E-03
8.62E-03
8.62E-03
7.76E-03
Tracheoesophageal fistula
Peripheral Nervous System Diseases
Cell Transformation, Neoplastic
Carcinoma, Transitional Cell
toll-like receptor 4 signaling pathway
regulation of chromatin organization
B cell receptor signaling pathway
cell junction organization
Neoplasm Invasiveness
meiotic chromosome segregation
regulation of transcription from RNA polymerase II
promoter in response to hypoxia
neuron apoptotic process
cellular response to decreased oxygen levels
negative regulation of neurogenesis
protein heterooligomerization
dorsal/ventral pattern formation
response to hydrogen peroxide
cell-cell junction
regulation of cell motility
glycerolipid biosynthetic process
regulation of type I interferon production
regulation of proteolysis involved in cellular protein
catabolic process
regulation of leukocyte differentiation
regulation of binding
Liver Neoplasms, Experimental
Adherens junction
Endothelin signaling pathway
sex chromosome
Downstream signal transduction
Prolonged ERK activation events
Estrogen signaling pathway
Signaling by constitutively active EGFR
Lymphoma, Large B-Cell, Diffuse
hair follicle morphogenesis
regulation of osteoblast differentiation
aromatic compound catabolic process
epithelial cell differentiation
negative regulation of epithelial cell proliferation
type I interferon production
regulation of glycoprotein biosynthetic process
multicellular organismal aging
growth hormone receptor signaling pathway
maintenance of protein location in cell
Signaling by FGFR
8.62E-03
8.62E-03
8.62E-03
8.62E-03
8.64E-03
8.64E-03
8.67E-03
8.68E-03
8.72E-03
8.73E-03
8.73E-03
8.73E-03
8.73E-03
8.73E-03
8.73E-03
8.73E-03
8.73E-03
8.78E-03
8.80E-03
8.80E-03
8.88E-03
8.88E-03
8.88E-03
8.88E-03
8.92E-03
8.94E-03
8.94E-03
8.94E-03
8.99E-03
8.99E-03
8.99E-03
8.99E-03
9.02E-03
9.18E-03
9.22E-03
9.22E-03
9.22E-03
9.22E-03
9.22E-03
9.26E-03
9.26E-03
9.26E-03
9.26E-03
9.32E-03
Signaling by ERBB2
B Cell Receptor Signaling Pathway
DAP12 signaling
T cell activation
Bacterial invasion of epithelial cells
Formation of incision complex in GG-NER
Type II diabetes mellitus
IGF-1 Signaling Pathway
SHC1 events in ERBB4 signaling
Dual incision reaction in GG-NER
Role of MEF2D in T-cell Apoptosis
organ growth
glycoprotein metabolic process
establishment of organelle localization
regulation of intracellular transport
programmed necrotic cell death
regulation of collagen biosynthetic process
regulation of myelination
regulation of Rac protein signal transduction
sarcomere organization
cellular response to growth hormone stimulus
positive regulation of glial cell differentiation
embryonic hindlimb morphogenesis
cellular protein complex assembly
cellular response to oxygen levels
transcription regulatory region DNA binding
transcription factor activity, transcription factor binding
9.41E-03
9.41E-03
9.41E-03
9.43E-03
9.43E-03
9.43E-03
9.43E-03
9.43E-03
9.43E-03
9.43E-03
9.43E-03
9.47E-03
9.47E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.67E-03
9.71E-03
9.75E-03
9.76E-03
9.76E-03
transcription factor activity, protein binding
regulatory region DNA binding
regulatory region nucleic acid binding
regulation of Ras protein signal transduction
N-acetyltransferase activity
Insulin Signaling
regulation of protein kinase B signaling
Regulation of nuclear SMAD2/3 signaling
core promoter binding
cell cortex
Signaling by Leptin
Ceramide Signaling Pathway
Apoptotic Signaling in Response to DNA Damage
Aspirin Blocks Signaling Pathway Involved in Platelet
Activation
9.76E-03
9.76E-03
9.76E-03
9.89E-03
9.92E-03
9.93E-03
9.96E-03
1.00E-02
1.00E-02
1.00E-02
1.00E-02
1.00E-02
1.00E-02
1.00E-02
EBV LMP1 signaling
Insulin Signaling Pathway
G1/S transition of mitotic cell cycle
1.00E-02
1.00E-02
1.01E-02
liver development
cell cycle G1/S phase transition
proximal/distal pattern formation
epithelial tube branching involved in lung
morphogenesis
MAPK signaling pathway
Integrin signalling pathway
SCF ubiquitin ligase complex
occluding junction
bicellular tight junction
CTCF: First Multivalent Nuclear Factor
GRB2 events in ERBB2 signaling
Inhibition of Cellular Proliferation by Gleevec
Multiple antiapoptotic pathways from IGF-1R signaling
lead to BAD phosphorylation
1.01E-02
1.01E-02
1.01E-02
1.01E-02
CCR3 signaling in Eosinophils
VEGFR3 signaling in lymphatic endothelium
Canonical NF-kappaB pathway
hepaticobiliary system development
negative regulation of homeostatic process
regulation of glycoprotein metabolic process
IRS-mediated signalling
regulation of protein complex assembly
intracellular steroid hormone receptor signaling
pathway
1.06E-02
1.06E-02
1.06E-02
1.06E-02
1.07E-02
1.07E-02
1.08E-02
1.10E-02
1.10E-02
maintenance of location in cell
positive regulation of multicellular organismal
metabolic process
epidermis morphogenesis
regulation of collagen metabolic process
negative regulation of gliogenesis
S1P2 pathway
Dorso-ventral axis formation
Physiological and Pathological Hypertrophy of the
Heart
1.12E-02
1.12E-02
Circadian Repression of Expression by REV-ERBA
Regulation of eIF4e and p70 S6 Kinase
Signaling by FGFR in disease
cellular response to external stimulus
T cell activation
NF-kappaB binding
centrosome
regulation of growth
cardiocyte differentiation
cellular response to lipopolysaccharide
immune effector process
1.13E-02
1.13E-02
1.13E-02
1.13E-02
1.13E-02
1.14E-02
1.14E-02
1.16E-02
1.16E-02
1.16E-02
1.17E-02
1.03E-02
1.05E-02
1.05E-02
1.05E-02
1.05E-02
1.06E-02
1.06E-02
1.06E-02
1.06E-02
1.12E-02
1.12E-02
1.12E-02
1.13E-02
1.13E-02
1.13E-02
IRS-related events
stem cell development
spinal cord motor neuron differentiation
inner ear receptor cell development
Signaling by EGFR
IRS-related events triggered by IGF1R
Apoptosis
RORA Activates Circadian Expression
Retinoic acid receptors-mediated signaling
EGF receptor (ErbB1) signaling pathway
SHC1 events in ERBB2 signaling
Nectin adhesion pathway
mCalpain and friends in Cell motility
EGFR1 Signaling Pathway
activation of immune response
stem cell maintenance
Carcinoma, Non-Small-Cell Lung
Signaling by EGFR in Cancer
RB in Cancer
cadherin binding
DAP12 interactions
Signaling by PDGF
Influenza A
DNA-dependent DNA replication
Regulation of BAD phosphorylation
WNT Signaling Pathway
The extracellular signal-regulated RAF/MEK/ERK
signaling
Nephrin/Neph1 signaling in the kidney podocyte
Influence of Ras and Rho proteins on G1 to S Transition
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.17E-02
1.18E-02
1.18E-02
1.19E-02
1.19E-02
1.19E-02
1.20E-02
1.20E-02
1.20E-02
1.20E-02
1.20E-02
1.22E-02
1.22E-02
1.22E-02
regulation of response to DNA damage stimulus
histone H3-K4 methylation
regulation of cellular carbohydrate catabolic process
1.22E-02
1.22E-02
1.22E-02
regulation of carbohydrate catabolic process
IGF1R signaling cascade
Signaling by Type 1 Insulin-like Growth Factor 1
Receptor (IGF1R)
1.22E-02
1.23E-02
1.23E-02
Genes related to Wnt-mediated signal transduction
1.23E-02
proteasome-mediated ubiquitin-dependent protein
catabolic process
1.23E-02
kidney development
positive regulation of protein complex assembly
digestive tract development
1.23E-02
1.24E-02
1.24E-02
1.22E-02
1.22E-02
maintenance of protein location
regulation of locomotion
Insulin receptor signalling cascade
Disease
Genes related to IL4 rceptor signaling in B lymphocytes
1.24E-02
1.24E-02
1.25E-02
1.25E-02
1.25E-02
Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
1.25E-02
3-phosphoinositide biosynthesis
Ephrin B reverse signaling
Cellular response to hypoxia
Myocyte Adrenergic Pathway is a specific case of the
generalized Adrenergic Pathway.
1.25E-02
1.25E-02
1.25E-02
1.25E-02
Signalling to RAS
Transcription factor CREB and its extracellular signals
1.25E-02
1.25E-02
Recycling pathway of L1
TGF-beta signaling pathway
regulation of epithelial cell proliferation
rhythmic process
collagen biosynthetic process
negative regulation of mitotic cell cycle
embryonic limb morphogenesis
cytokinesis
embryonic appendage morphogenesis
sequence-specific DNA binding
cell-type specific apoptotic process
GnRH signaling pathway
perinuclear region of cytoplasm
embryonic epithelial tube formation
endothelial cell migration
cellular response to molecule of bacterial origin
response to growth hormone
response to cocaine
regulation of G1/S transition of mitotic cell cycle
pallium development
epithelial tube formation
regulation of cellular component movement
Interferon-gamma signaling pathway
Growth Hormone Signaling Pathway
regulation of cell cycle G1/S phase transition
histone acetylation
Adenocarcinoma of lung
acetyltransferase activity
N-acyltransferase activity
apical junction complex
1.25E-02
1.25E-02
1.26E-02
1.27E-02
1.27E-02
1.27E-02
1.28E-02
1.28E-02
1.28E-02
1.28E-02
1.28E-02
1.29E-02
1.29E-02
1.30E-02
1.30E-02
1.30E-02
1.32E-02
1.32E-02
1.32E-02
1.32E-02
1.32E-02
1.33E-02
1.33E-02
1.33E-02
1.34E-02
1.34E-02
1.35E-02
1.36E-02
1.36E-02
1.36E-02
regulation of transcription from RNA polymerase II
promoter in response to stress
necrotic cell death
Inflammation mediated by chemokine and cytokine
signaling pathway
ubiquitin-dependent protein catabolic process
Reelin signaling pathway
VEGFR1 specific signals
MAPK Cascade
Links between Pyk2 and Map Kinases
response to metal ion
chemotaxis
internal peptidyl-lysine acetylation
taxis
microtubule anchoring
regulation of organelle assembly
renal system development
regulation of protein polymerization
morphogenesis of an epithelium
Toll Like Receptor 3 (TLR3) Cascade
MyD88-independent cascade
CD40/CD40L signaling
Canonical Wnt signaling pathway
Axon guidance mediated by netrin
Dual incision reaction in TC-NER
MAPK targets/ Nuclear events mediated by MAP
kinases
Formation of transcription-coupled NER (TC-NER) repair
complex
Cell surface interactions at the vascular wall
protein localization
hindlimb morphogenesis
cardiac muscle cell proliferation
digestive system development
phosphatidylinositol metabolic process
regulation of innate immune response
intracellular receptor signaling pathway
regulation of body fluid levels
modification-dependent protein catabolic process
regulation of neuron differentiation
Myb_DNA-bd
internal protein amino acid acetylation
modification-dependent macromolecule catabolic
process
regulation of protein acetylation
telomere maintenance via telomere lengthening
1.37E-02
1.37E-02
1.39E-02
1.40E-02
1.40E-02
1.40E-02
1.40E-02
1.40E-02
1.40E-02
1.41E-02
1.41E-02
1.42E-02
1.43E-02
1.43E-02
1.43E-02
1.43E-02
1.43E-02
1.45E-02
1.45E-02
1.46E-02
1.46E-02
1.46E-02
1.46E-02
1.46E-02
1.46E-02
1.46E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.48E-02
1.49E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
hair cell differentiation
response to cadmium ion
cellular response to acid chemical
mammary gland development
tube formation
negative regulation of neuron apoptotic process
toll-like receptor signaling pathway
response to acid chemical
positive regulation of cytokine production
positive regulation of epithelial cell differentiation
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.50E-02
1.51E-02
1.51E-02
cell cycle DNA replication
thymus development
positive regulation of protein ubiquitination
ARM
Estrogen signaling pathway
CDO in myogenesis
Myogenesis
EGF Signaling Pathway
Aurora A signaling
Arm
Myb_DNA-binding
BROMODOMAIN_1
Bromodomain
MYB_LIKE
ARM_REPEAT
BROMODOMAIN_2
BROMO
Bromodomain
Armadillo
Bromodomain
pattern specification process
negative regulation of cell development
skin morphogenesis
positive regulation of neural precursor cell proliferation
1.51E-02
1.51E-02
1.51E-02
1.52E-02
1.53E-02
1.53E-02
1.53E-02
1.53E-02
1.53E-02
1.53E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.55E-02
1.56E-02
1.56E-02
1.56E-02
1.56E-02
peptidyl-lysine methylation
regulation of multicellular organismal metabolic
process
1.56E-02
1.56E-02
Wnt Signaling Pathway and Pluripotency
NGF signalling via TRKA from the plasma membrane
1.56E-02
1.57E-02
chromatin binding
Regulation of toll-like receptor signaling pathway
Ovarian Infertility Genes
Oncogene Induced Senescence
1.59E-02
1.59E-02
1.60E-02
1.60E-02
PDGF Signaling Pathway
regulation of small GTPase mediated signal
transduction
Toll-like receptor signaling pathway
ErbB1 downstream signaling
maintenance of location
regulation of DNA-templated transcription in response
to stress
striated muscle cell development
Chagas disease (American trypanosomiasis)
T cell receptor signaling pathway
3p21
EPHB forward signaling
E-cadherin signaling in the nascent adherens junction
1.60E-02
1.61E-02
Synthesis of PIPs at the plasma membrane
Syndecan-2-mediated signaling events
Fcgamma receptor (FCGR) dependent phagocytosis
1.66E-02
1.66E-02
1.67E-02
cellular response to biotic stimulus
CD molecules
membrane raft
transcription-coupled nucleotide-excision repair
cell adhesion mediated by integrin
Toll-like receptor signaling pathway
placenta development
Wnt/beta-catenin Pathway
HIF-2-alpha transcription factor network
Global Genomic NER (GG-NER)
CXCR3-mediated signaling events
Senescence and Autophagy
organelle localization
somatic stem cell maintenance
ventral spinal cord development
myofibril assembly
Rap1 signaling pathway
Signal transduction by L1
CARM1 and Regulation of the Estrogen Receptor
IL1-mediated signaling events
regulation of cytokinesis
lipopolysaccharide-mediated signaling pathway
negative regulation of chromosome organization
dendrite
cellular response to organic cyclic compound
cell maturation
leukocyte migration
1.67E-02
1.67E-02
1.68E-02
1.68E-02
1.68E-02
1.71E-02
1.73E-02
1.73E-02
1.73E-02
1.73E-02
1.73E-02
1.73E-02
1.74E-02
1.74E-02
1.74E-02
1.74E-02
1.80E-02
1.80E-02
1.80E-02
1.80E-02
1.81E-02
1.81E-02
1.81E-02
1.82E-02
1.82E-02
1.83E-02
1.84E-02
1.61E-02
1.61E-02
1.62E-02
1.62E-02
1.64E-02
1.65E-02
1.65E-02
1.66E-02
1.66E-02
1.66E-02
Mouth Neoplasms
Signaling events mediated by TCPTP
bicellular tight junction assembly
striated muscle cell proliferation
positive regulation of I-kappaB kinase/NF-kappaB
signaling
PI3K-Akt signaling pathway
Cholinergic synapse
Signaling by Insulin receptor
ALK in cardiac myocytes
BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.85E-02
1.87E-02
1.87E-02
1.87E-02
1.89E-02
G alpha 13 Pathway
Signalling to ERKs
positive regulation of myeloid leukocyte differentiation
1.93E-02
1.93E-02
1.93E-02
Rac protein signal transduction
protein export from nucleus
morphogenesis of embryonic epithelium
cellular homeostasis
SANT
androgen receptor binding
muscle cell development
somatodendritic compartment
positive regulation of histone modification
response to fatty acid
spindle assembly
neuron projection
SANT_DNA-bd
FBOX
positive regulation of immune system process
urogenital system development
regulation of cellular localization
negative regulation of molecular function
prostate gland development
artery morphogenesis
single organismal cell-cell adhesion
small GTPase mediated signal transduction
negative regulation of protein binding
centrosome cycle
histone H3 acetylation
IL-2 Receptor Beta Chain in T cell Activation
ubiquitin-protein transferase activity
estrogen receptor binding
nuclear hormone receptor binding
Signaling by Interleukins
1.93E-02
1.93E-02
1.94E-02
1.94E-02
1.95E-02
1.95E-02
1.97E-02
1.98E-02
1.99E-02
1.99E-02
1.99E-02
2.00E-02
2.01E-02
2.01E-02
2.02E-02
2.02E-02
2.02E-02
2.02E-02
2.02E-02
2.02E-02
2.02E-02
2.02E-02
2.03E-02
2.03E-02
2.03E-02
2.03E-02
2.04E-02
2.04E-02
2.04E-02
2.04E-02
1.91E-02
1.93E-02
1.93E-02
1.93E-02
1.93E-02
positive regulation of immune response
sensory organ development
response to reactive oxygen species
regulation of transport
FRS2-mediated cascade
Leukocyte transendothelial migration
Ras signaling pathway
endonuclease activity
exocytosis
lipid modification
lateral plasma membrane
cell differentiation in spinal cord
identical protein binding
cellular response to oxidative stress
Endometrial Neoplasms
intercalated disc
glycerolipid metabolic process
pattern recognition receptor signaling pathway
B Cell Antigen Receptor
kidney morphogenesis
lung morphogenesis
positive regulation of cell adhesion
myelin sheath
Nerve Degeneration
innate immune response-activating signal transduction
2.06E-02
2.07E-02
2.08E-02
2.08E-02
2.12E-02
2.12E-02
2.12E-02
2.13E-02
2.13E-02
2.14E-02
2.14E-02
2.16E-02
2.16E-02
2.16E-02
2.18E-02
2.19E-02
2.19E-02
2.19E-02
2.21E-02
2.22E-02
2.22E-02
2.22E-02
2.24E-02
2.25E-02
2.28E-02
regulation of Notch signaling pathway
apical junction assembly
inner ear receptor cell differentiation
F-box_dom_Skp2-like
Neoplasm Metastasis
positive regulation of DNA replication
regulation of intracellular steroid hormone receptor
signaling pathway
2.28E-02
2.28E-02
2.28E-02
2.33E-02
2.33E-02
2.35E-02
2.35E-02
histone deacetylase complex
nuclear body
branching morphogenesis of an epithelial tube
regulation of stress-activated MAPK cascade
central nervous system neuron differentiation
cell-cell signaling
artery development
cardiac muscle tissue growth
positive regulation of response to DNA damage
stimulus
Cell Cycle Checkpoints
epithelial cell migration
2.37E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.41E-02
2.42E-02
epithelium migration
regulation of stress-activated protein kinase signaling
cascade
epidermal cell differentiation
negative regulation of intracellular signal transduction
2.42E-02
2.42E-02
cartilage development
positive regulation of canonical Wnt signaling pathway
2.46E-02
2.46E-02
embryonic digit morphogenesis
cardiac muscle cell development
response to dsRNA
retroviral 3' processing activity
retroviral integrase activity
T/G mismatch-specific endonuclease activity
integrase activity
hormone receptor binding
response to carbohydrate
activation of innate immune response
cardiac muscle tissue development
endocytosis
adherens junction assembly
repressing transcription factor binding
double-stranded RNA binding
striated muscle tissue development
tissue migration
protein polyubiquitination
synaptic transmission
positive regulation of smooth muscle cell proliferation
2.46E-02
2.46E-02
2.46E-02
2.47E-02
2.47E-02
2.47E-02
2.47E-02
2.47E-02
2.47E-02
2.47E-02
2.47E-02
2.48E-02
2.48E-02
2.49E-02
2.49E-02
2.49E-02
2.49E-02
2.49E-02
2.49E-02
2.51E-02
Oxidative Stress Induced Senescence
Colonic Neoplasms
Bioactive Peptide Induced Signaling Pathway
side of membrane
cytoplasmic side of plasma membrane
cell-cell contact zone
replication fork
RNA polymerase II transcription factor complex
PDGF signaling pathway
Arf6 trafficking events
Ceramide signaling pathway
PLK1 signaling events
Regulation of Microtubule Cytoskeleton
outflow tract morphogenesis
mechanoreceptor differentiation
actomyosin structure organization
2.51E-02
2.52E-02
2.52E-02
2.53E-02
2.53E-02
2.53E-02
2.54E-02
2.54E-02
2.55E-02
2.57E-02
2.57E-02
2.57E-02
2.57E-02
2.58E-02
2.58E-02
2.58E-02
2.42E-02
2.43E-02
androgen receptor signaling pathway
F-box
F-box_dom_cyclin-like
ERK1 and ERK2 cascade
Neighborhood of RRM1
Neighborhood of HDAC2
Genes in module_197
toll-like receptor 10 signaling pathway
cardiac cell development
G2/M Checkpoints
T Cell Signal Transduction
Signaling by FGFR mutants
tissue morphogenesis
regulation of nucleocytoplasmic transport
protein polymerization
organelle assembly
positive regulation of muscle cell differentiation
cellular carbohydrate catabolic process
glycerophospholipid biosynthetic process
FBOX
Osteoclast differentiation
Members of the BCR signaling pathway
Keratinocyte Differentiation
Transcription-coupled NER (TC-NER)
canonical Wnt signaling
embryonic morphogenesis
heart growth
activation of MAPKK activity
toll-like receptor 5 signaling pathway
regulation of endopeptidase activity
p53 binding
ubiquitin ligase complex
Tight junction
T Cell Receptor Signaling Pathway
FGF signaling pathway
Heart Development
Nucleotide excision repair
positive regulation of catabolic process
muscle tissue development
Natural killer cell mediated cytotoxicity
single organism cell adhesion
glycolytic process
response to ammonium ion
Notch-mediated HES/HEY network
Notch signaling pathway
epithelial cell development
2.58E-02
2.58E-02
2.58E-02
2.62E-02
2.63E-02
2.63E-02
2.63E-02
2.65E-02
2.65E-02
2.67E-02
2.67E-02
2.67E-02
2.68E-02
2.68E-02
2.68E-02
2.70E-02
2.71E-02
2.71E-02
2.71E-02
2.74E-02
2.75E-02
2.75E-02
2.75E-02
2.75E-02
2.75E-02
2.76E-02
2.77E-02
2.77E-02
2.77E-02
2.77E-02
2.82E-02
2.82E-02
2.82E-02
2.82E-02
2.82E-02
2.82E-02
2.82E-02
2.84E-02
2.85E-02
2.85E-02
2.87E-02
2.91E-02
2.91E-02
2.92E-02
2.92E-02
2.92E-02
forebrain development
somitogenesis
DNA methylation or demethylation
cellular response to mechanical stimulus
Signal Transduction
neuron projection guidance
axon guidance
response to osmotic stress
toll-like receptor TLR6:TLR2 signaling pathway
toll-like receptor TLR1:TLR2 signaling pathway
cytoplasmic side of membrane
MAP kinase activation in TLR cascade
macromolecule methylation
regulation of cysteine-type endopeptidase activity
involved in apoptotic process
2.92E-02
2.92E-02
2.92E-02
2.92E-02
2.96E-02
2.98E-02
2.98E-02
2.98E-02
2.98E-02
2.98E-02
2.99E-02
3.02E-02
3.04E-02
3.04E-02
cardiac ventricle morphogenesis
regulation of biomineral tissue development
peptidyl-threonine phosphorylation
osteoblast differentiation
telencephalon development
positive regulation of MAP kinase activity
phagocytosis
MAPK signaling pathway
protein autophosphorylation
DNA catabolic process, endonucleolytic
Downstream signaling in naive CD8+ T cells
regulation of peptidase activity
Axon guidance
Nucleotide Excision Repair
Role of Calcineurin-dependent NFAT signaling in
lymphocytes
3.04E-02
3.04E-02
3.04E-02
3.06E-02
3.06E-02
3.06E-02
3.06E-02
3.06E-02
3.09E-02
3.11E-02
3.12E-02
3.15E-02
3.17E-02
3.21E-02
3.21E-02
Genes related to the insulin receptor pathway
PI Metabolism
presynaptic membrane
regulation of phosphatidylinositol 3-kinase signaling
3.21E-02
3.21E-02
3.22E-02
3.26E-02
toll-like receptor 9 signaling pathway
histone methyltransferase complex
cellular component assembly involved in
morphogenesis
3.26E-02
3.27E-02
3.28E-02
morphogenesis of a branching epithelium
Signaling events mediated by Stem cell factor receptor
(c-Kit)
3.28E-02
3.32E-02
regulation of cell morphogenesis
in utero embryonic development
peptidyl-threonine modification
3.32E-02
3.32E-02
3.32E-02
regulation of generation of precursor metabolites and
energy
toll-like receptor 2 signaling pathway
negative regulation of response to stimulus
nucleocytoplasmic transport
positive regulation of protein kinase B signaling
regulation of neural precursor cell proliferation
Melanoma
Endothelins
positive regulation of myeloid cell differentiation
negative regulation of cysteine-type endopeptidase
activity involved in apoptotic process
3.32E-02
cell projection part
positive regulation of innate immune response
Cell Cycle, Mitotic
nuclear transport
regulation of cell projection organization
phospholipid biosynthetic process
response to cytokine
T cell differentiation in thymus
regulation of organ growth
positive regulation of cell division
pyrimidine-containing compound metabolic process
3.49E-02
3.50E-02
3.52E-02
3.52E-02
3.52E-02
3.53E-02
3.53E-02
3.53E-02
3.53E-02
3.53E-02
3.53E-02
centrosome organization
Stabilization of p53
protein O-linked glycosylation
glial cell development
histone lysine methylation
somite development
core promoter sequence-specific DNA binding
beta-catenin binding
transcriptional repressor complex
basolateral plasma membrane
RAC1 signaling pathway
Basal cell carcinoma
TGF Beta Signaling Pathway
organonitrogen compound catabolic process
nuclease activity
SMAD binding
transferase activity, transferring acyl groups other than
amino-acyl groups
3.53E-02
3.54E-02
3.60E-02
3.60E-02
3.60E-02
3.60E-02
3.61E-02
3.61E-02
3.61E-02
3.61E-02
3.64E-02
3.64E-02
3.64E-02
3.64E-02
3.64E-02
3.64E-02
3.64E-02
response to inorganic substance
morphogenesis of a branching structure
3.65E-02
3.66E-02
3.34E-02
3.36E-02
3.40E-02
3.40E-02
3.40E-02
3.40E-02
3.43E-02
3.48E-02
3.48E-02
negative regulation of cysteine-type endopeptidase
activity
negative regulation of protein metabolic process
regulation of intracellular protein transport
regulation of I-kappaB kinase/NF-kappaB signaling
Neurotrophic factor-mediated Trk receptor signaling
3.67E-02
Circadian Clock
MyD88-dependent toll-like receptor signaling pathway
3.75E-02
3.75E-02
secretion by cell
TGF-beta Receptor Signaling Pathway
Coregulation of Androgen receptor activity
nucleic acid phosphodiester bond hydrolysis
response to heat
microtubule organizing center organization
platelet activation
chromatin DNA binding
8q24.3
immune response-activating cell surface receptor
signaling pathway
cell-cell junction assembly
regulation of cellular amine metabolic process
DNA modification
carbohydrate metabolic process
connective tissue development
Esophageal Squamous Cell Carcinoma
establishment of synaptic vesicle localization
synaptic vesicle transport
histone acetyltransferase complex
histone deacetylase binding
p53-Dependent G1 DNA Damage Response
p53-Dependent G1/S DNA damage checkpoint
negative regulation of protein modification process
3.76E-02
3.79E-02
3.79E-02
3.82E-02
3.82E-02
3.82E-02
3.85E-02
3.86E-02
3.88E-02
3.89E-02
regulation of protein serine/threonine kinase activity
4.04E-02
Long-term depression
mTOR signaling pathway
Leptin signaling pathway
Wnt Signaling Pathway
regulation of striated muscle cell differentiation
synaptic vesicle localization
positive regulation of Wnt signaling pathway
pancreas development
protein localization to organelle
4.09E-02
4.09E-02
4.09E-02
4.09E-02
4.09E-02
4.11E-02
4.11E-02
4.11E-02
4.13E-02
3.67E-02
3.68E-02
3.68E-02
3.75E-02
3.89E-02
3.89E-02
3.89E-02
3.90E-02
3.92E-02
3.94E-02
3.96E-02
3.96E-02
3.98E-02
3.98E-02
4.00E-02
4.00E-02
4.02E-02
axis specification
establishment of cell polarity
spinal cord development
p75(NTR)-mediated signaling
Shigellosis
Inositol phosphate metabolism
PROTEIN_KINASE_ATP
phosphoric ester hydrolase activity
glycerophospholipid metabolic process
G1/S DNA Damage Checkpoints
developmental maturation
synapse
methyltransferase complex
cell junction
negative regulation of canonical Wnt signaling pathway
4.18E-02
4.18E-02
4.18E-02
4.19E-02
4.19E-02
4.19E-02
4.21E-02
4.22E-02
4.28E-02
4.31E-02
4.32E-02
4.32E-02
4.32E-02
4.32E-02
4.34E-02
regulation of reproductive process
ARM-like
ARM-like
negative regulation of signal transduction
chemical homeostasis
response to lipopolysaccharide
segmentation
I-kappaB kinase/NF-kappaB signaling
acetyltransferase complex
protein acetyltransferase complex
cerebral cortex development
pyruvate metabolic process
phosphatidylinositol 3-kinase signaling
columnar/cuboidal epithelial cell differentiation
Neighborhood of BUB1
endodeoxyribonuclease activity
protease binding
enzyme regulator activity
perikaryon
carbohydrate derivative catabolic process
Alzheimer disease-amyloid secretase pathway
Fas Signaling Pathway
17p11.2
skeletal system development
ameboidal-type cell migration
regulation of cell-cell adhesion
cardiac muscle cell differentiation
Downstream Signaling Events Of B Cell Receptor (BCR)
4.34E-02
4.34E-02
4.34E-02
4.35E-02
4.37E-02
4.42E-02
4.42E-02
4.42E-02
4.45E-02
4.45E-02
4.45E-02
4.45E-02
4.45E-02
4.45E-02
4.48E-02
4.59E-02
4.59E-02
4.59E-02
4.59E-02
4.61E-02
4.63E-02
4.63E-02
4.64E-02
4.70E-02
4.70E-02
4.70E-02
4.70E-02
4.71E-02
Wnt signaling pathway
4.71E-02
DNA Damage/Telomere Stress Induced Senescence
4.72E-02
AGE/RAGE pathway
histone methylation
spindle organization
adherens junction organization
cellular component disassembly
regulation of establishment of protein localization
negative regulation of binding
protein domain specific binding
Genes related to PIP3 signaling in cardiac myocytes
4.72E-02
4.75E-02
4.75E-02
4.75E-02
4.75E-02
4.75E-02
4.75E-02
4.77E-02
4.81E-02
Kit Receptor Signaling Pathway
Cyclin A:Cdk2-associated events at S phase entry
superpathway of inositol phosphate compounds
DNA-dependent ATPase activity
G1 to S cell cycle control
transferase activity, transferring acyl groups
Prot_kinase_cat_dom
Degradation of beta-catenin by the destruction
complex
regulation of cell morphogenesis involved in
differentiation
positive regulation of transport
4.81E-02
4.81E-02
4.81E-02
4.88E-02
4.89E-02
4.91E-02
4.95E-02
4.97E-02
5.00E-02
5.00E-02