Skeletal System Types of Animal Skeletons • Endoskeleton – Internal skeleton Ex. Humans • Exoskeleton – External skeleton Ex. Insects, Clams • Hydrostatic – Internal fluids receive and redistribute applied forces Ex. Annelids Bone Functions • • • • Movement Protection Support Mineral Storage (Ca++, P) • Energy Storage (Yellow Marrow – Fat) • Hematopoiesis - Produce Blood Cells (Red Marrow) Types of Bones Name Long Short -Sesamoid Flat Irregular Characteristics Longer than they are wide cube shaped Sesame seed shaped, formed in tendon flattened section more than 1 shape Examples femur, humerus, other limb bones except wrist, ankles, and patella carpals, tarsals patella cranium, ribs, scapula vertebrae, mandible, hip bones Classification of Bones (cont.) a = Long Bone b = Short Bone c = Flat Bone d = Irregular Bone e = Sesamoid Bone Anatomy of a Long Bone Epiphyseal Plate: hyaline cartilage that grows during childhood to lengthen the bone Epiphyseal Line: remnant of epiphyseal plate, found only in adults Epiphysis: shorter section at end Diaphysis: long portion in middle Epiphysis Periosteum: Compact Bone: dense layer over medullary cavity; supports weight Bone covering, outer layer of dense irregular c.t.; inner layer of osteoblasts and osteoclasts, supplied with nerves and blood vessels Spongy Bone: lattice of trabecula filled with red marrow; nourished directly from circulating blood Medullary Cavity: Hollow center of diaphysis, contains yellow marrow Articular Cartliage: Covers epiphysis at joints, reduces friction, absorbs shock Bone (Osseous) Tissue Osteocytes – widely spaced, surrounded by intercellular substances Osteoblasts: add salts Osteoid (organic): Collagenous Fibers Hydroxyapatite Osteoclasts: remove salts (inorganic): Mineral Salts (calcium, phosphorus) - Provides strength and hardness to bone Osteon: structural unit of matrix and canals • • • • • Lamella (little plate): rings of calcified matrix, intercellular substance Volkmann’s Canals: horizontal canals; allow blood vessels and nerves to connect Haversian Canals: vertical canals; allow blood vessels and nerves to connect Canaliculi: tiny canals that allow osteocytes to exchange nutrients and wastes Lacunae: space for osteocytes Ossification (bone formation) • begins around 6th or 7th week post conception • ends by age 25 2 types Intramembranous Ossification • Bone forms within fibrous membranes (skull, clavicle) – Osteoblasts cluster in fibrous membranes: Center of Ossification – Calcification: intercellular substances and collagen are secreted into a network where calcium can be deposited – Trabecula Formation: complete when osteoblasts are completely surrounded by calcified matrix – Trabecula continue to fuse together = spongy bone – Red marrow fills in space Endochondral Ossification (most bones) • Cartilage is formed in embryonic stage – Covered by perichondrium (membrane) Primary Ossification: Begins at periosteal collar (around middle of diaphysis) - Blood vessel penetrates perichondrium - Stimulates osteoblast formation - Bone replaces cartilage: - Intercellular substances calcify - Nutrients are cut off by hardened matrix Secondary Ossification: - Periosteum thickens bones, especially at ends - Blood vessel penetrates ends, process repeats EXCEPT - 2 areas of cartilage will remain: - articulating cartilage - epiphyseal plates (allow lengthwise growth of bones) Bone Remodeling • Normal bone is always undergoing remodeling • Removes old bone tissue and replaces it with new bone tissue • Remodeling cycle continues throughout life to maintain healthy bone • About 20% of all bone tissue is replaced annually Bone Remodeling • Sites of remodeling – Where bone is experiencing growth – Mechanical stress – Microfractures – Breaks Bone Remodeling Five Phases 1. 2. 3. 4. 5. Activation Resorption Reversal Formation Quiescence Bone Remodeling • Activation 1. Pre-osteoclasts are attracted to the remodeling sites 2. Pre-osteoclasts fuse to form multinucleated osteoclasts • Resporption 3. Osteoclasts dig out a cavity, called a resorption pit, in spongy bone or burrow a tunnel in compact bone Bone Remodeling 4. Calcium can be released into the blood for use in various body functions 5. Osteoclasts disappear • Reversal 6. Mesenchymal stem cells, pre-cursors to osteoblasts, appear along the burrow or pit where they… 7. …proliferate (increase in number) and differentiate into preosteoblasts Bone Remodeling • Formation 8. Pre-osteoblasts mature into osteoblasts at the surface of the burrow or pit 9. Osteoblasts release osteoid at the site, forming a new soft matrix 10. The new matrix is mineralized with calcium and phosphorous • Quiescence 11. Site remains dormant until the next cycle System Divisions • Axial – – – – Backbone Skull Ribs Sternum • Appendicular – Everything Else Axial Skeleton Axial Skeleton • Skull – All bones immovable except mandible – Cranium • Paranasal Sinuses – Cavities within bones of skull – Lined by mucous membranes • Fontanels – Fetal/Child » Soft spots » Incomplete Ossification – Facial Bones Fontanels of fetal skull Axial Skeleton • Hyoid Bone – No articulation Axial Skeleton • Vertebral Column – Protects spinal cord – Shock absorbers – Vertebrae separated by intervertebral disks • Fibrocartilage Axial Skeleton • 7 Cervical Vertebrae – Atlas (C1) and Axis (C2) • Allow rotation of the head • 12 Thoracic Vertebrae • 5 Lumbar Vertebrae • Remember the common mealtimes to help you remember the number of vertebrae – Breakfast = 7, Lunch = 12, Dinner = 5 Axial Skeleton • Sacrum – Five fused vertebrae • Coccyx – Tailbone • Bony Thorax • Sternum •Manubrium, Body, Xiphoid process •12 pairs of ribs Axial Skeleton • Ribs – True ribs • Attached to sternum • 7 pair – False ribs • Attached to costalcartilage of 7th rib • 3 pair – Floating ribs • No anterior attachment • 2 pair Appendicular Skeleton Appendicular Skeleton • Pectoral (shoulder) girdle – Scapula and clavicle (collar bone) • Upper limbs – Humerus (arm) – Radius and ulna (forearm) • Carpals (wrist) • Metacarpals (palm) • Phalanges (fingers and thumb) Appendicular Skeleton • Pelvic (hip) Girdle – Coxal (hip) bones Female vs. Male Female Pubic arch = 90˚ Distance between iliac crest wider Male Pubic arch = 60˚ Bones are heavier Bone markings more prominent Appendicular Skeleton • Coxal Bones have 3 parts 1. Ilium (superior) 2. Ischium (posterior) 3. Pubis (anterior) Appendicular Skeleton • Lower Limbs – Femur (thigh) • Longest bone in body – Tibia and Fibula (leg) • Tibia = medial, Fibula = lateral – Patella (knee cap) – Tarsals • Ankle – Metatarsals • Instep – Phalanges • toes Joints • Points of contact between bones • Functions – Hold skeleton together – Mobility Joints (based on functional differences) (Articulations) Synarthroses (axial) Amphiarthroses (axial) Diarthroses (appendicular) Synarthroses (Fibrous Joints) • No Movement Joining bones connected by fibrous connective tissue Example: sutures in skull, teeth Amphiarthroses (Cartilaginous joints) • Slight Movement Joining bones connected by cartilage Example: vertebral joints Diarthroses (Synovial) • Free Movement Surrounded by synovial cavity: - lined with synovial membrane - lubricates bones/cartilage - structured like a sleeve - bursa often found between the bones - ligaments secure bone together - grow out of periosteum Types of Diarthrotic Joints Ball and Socket Hinge Head of one bone fits in concave socket of another bone Allows widest range of motion Head of one bone fits against concave socket of another Allows only flexion and extension Pivot Small pin of one bone fits in arch of another Allows rotation Saddle Gliding Only found where thumb fits wrist Allows movement in many directions Flat surfaces of bones fit against each other Allows little directional movement, only gliding Condyloid/Ellipsoid Oval projection fits into an elliptical socket Allows most movement, no rotation