15 14 13 12 11 10 9 8 7 6 5 4 3 2 1 $1 MILLION $500,000 $250,000 $125,000 $64,000 $32,000 $16,000 $8,000 $4,000 $2,000 $1,000 $500 $300 $200 $100 During protein synthesis, the amino acid sequence is determined by the _________ A. Signals Sent by the plasma membrane C. ATP produced by mitochondria B. Genetic code in the DNA molecule D. Number of mitochondria in the cell Synthesis of a defective protein may result from an alteration in the A. Cell’s Fat Concentration B. Base sequence code in DNA C. Shape of the nucleus D. Number of mitochondria The function of ribosomal RNA (rRNA) is to A. Transfer an amino acid to the ribosome B. Carry the genetic information coded in DNA C. Copy the genetic code present in mRNA D. Form ribosomes, the sites of protein synthesis The function of messenger RNA (mRNA) is to A. Carry Amino Acids to the ribosome C. Translate the base sequence at the ribosomes B. Make a copy of the DNA instructions and bring it to the ribosome D. Prevent DNA mutations during replication The process by which DNA’s information is copied into RNA is called A. Transcription C. Synthesis B. Translation D. Polymerization Which of the following represents the codons that correspond to the segment TATCAGGAT of DNA? A. ATA-GTC-CTA B. TCA-CUG-GUA C. AUA-GUC-CUA D. ACA-CUC-GUA What is the name of the enzyme that initiates transcription? A. DNA Polymerase B. ATP Synthase C. RNA Polymerase D. Transformation principle Eukaryotic mRNA molecules are occasionally interspersed with noncoding sequences that must be removed before protein synthesis. These are ________. A. Introns B. Anticodons C. Nucleosomes D. Chromosomes What class of RNA binds free amino acids and carries them to ribosomes? A. tRNA B. rRNA C. mRNA D. None of them Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below. What type of mutation is depicted in this sequence? A. Insertion B. Substitution C. Deletion D. Frameshift Which of the following polypeptides is coded for by the mRNA sequence 5’ AUGGUUAAACGACAAUCC 3’? A. Val-lys-Phe-Gly-Ser B. Met-Val-Lys-Arg-Gln-Ser C. Met-Asp-Phe-Ala-Arg D. Ile-Gln-Lys-Asp-Gly-Leu-Ser Which cellular process takes place in the ribosomes that are bound to the endoplasmic reticulum? A. The synthesis of new proteins C. The conversion of radiant energy to glucose B. The breakdown of waste material D. The replication of nucleic acid A mutation is least likely to affect a cell when the mutation — A. Reverses the order of bases in a DNA strand C. Replaces a base with complementary base B. Produces a triplet that codes for the same amino acid as the original strand D. Allows the total number of bases in a DNA sequence to remain the same In 1917 the biologist Thomas Hunt Morgan conducted studies in which he kept some caterpillars in the dark and placed some others under red, green, or blue lights. Exposure to red light produced butterflies with brightly colored wings. Exposure to green light resulted in dark-colored wings. Exposure to blue light or no light resulted in pale-colored wings. What was the most likely conclusion of Morgan’s research? A. The pigment in butterfly wings absorbs light from the environment. B. The phenotypic expression of wing shape depends on color pigmentation in butterflies C. The genes regulating wing color in D. Caterpillars exposed to red and green light butterflies are influenced by environmental factors are healthier than caterpillars exposed to no light or blue light. The many different functions and behaviors of living organisms are essentially based on the performance of their cells. The cell’s performance in turn is dependent upon the A. Production of steroids and hormones C. Production of correct membranes B. Production of many varieties of polypeptides and proteins D. Ability to reproduce End of Game Instructions & answer slides follow Setting up Game • • • • • Use the Edit menu and Replace… to insert questions and answers. In the Find box, type in “Question X” (where X is the question number, 1 through 15). In the Replace box, type in the question. Then, enter “Answer X-1” and the first answer, “Answer X-2” and the second answer, etc. (Capitalize as indicated.) To set up the 50-50 Lifeline slides (Slides 37-51): – 1. Select the first answer to be eliminated by clicking on the text of the answer. Select the text and delete it. (This should leave a blank hexagon.) – 2.Repeat with the second eliminated answer, and then repeat with each further slide. To set up the Answer slides (Slides 21-35): – 1. Select the hexagon behind the correct answer by right-clicking on the hexagon. (Click above or below the answer text to avoid selecting the text instead. Once selected, the hexagon should have a rectangular border around it.) Select Format Autoshape; choose the Colors and Lines tab, choose the Fill color and change its color to light green. (The green should be provided in the bottom row of colors.) – 2. Repeat with each further slide. Slides 52-66 are the Money Won slides. On the title screen, the finger icon will link to a Fastest Finger slide, if you would like to use it. To set up the Fastest Finger slide (Slide 70), fill in the Fastest Finger question, and the four answers. On the answer slide (Slide 71), replace each orange question mark with the letter of the appropriate answer in order, starting at the top. Fill in the answer corresponding to each letter accordingly. Clicking on the ? icon on Slide 70 will go to the answer slide; clicking on the house icon will link to the main game board. USAGE NOTE: the Fastest Finger question slide includes the music for Fastest Finger; this music is 25 seconds long. Use the music as a timer; when the music ends, go to the answer slide. Setting up Game • • • • The Phone-a-Friend lifeline can be used to ask one other student to help out. Clicking on the Phone-a-Friend lifeline icon will link to a 30-second timer slide. The timer will begin on a mouse-click, and will count down to zero. Once the slide reaches zero, clicking on the curved arrow icon will return to the previous slide (the question slide). USAGE NOTE: the question and answers are not visible during the clock countdown, and returning to the question slide before the clock finishes will reset the clock. The Ask-the-Audience lifeline can be used to ask the entire class, who gives their votes for the correct answer by letter. Clicking on the Ask-the-Audience lifeline icon will link to a chart slide. Clicking on the chart will open Microsoft Excel; click on the “Enter Scores Here” tab to enter the class votes for each answer, then click on the “Chart” tab so the chart will be visible. Go to the File menu and choose Close and Return… to return to the slide show. Clicking on the curved arrow icon will return to the previous slide (the question slide). ICONS: – ? Takes you to the answer slide – Star Takes you from the answer slide to the Money Won slide – House Takes you back to the Cash Board If using the game for another person or another class, close the game and re-open it (this is to reset the links on the game board back to orange). During protein synthesis, the amino acid sequence is determined by the _________ A. Signals Sent by the plasma membrane C. ATP produced by mitochondria B. Genetic code in the DNA molecule D. Number of mitochondria in the cell Synthesis of a defective protein may result from an alteration in the A. Cell’s Fat Concentration B. Base sequence code in DNA C. Shape of the nucleus D. Number of mitochondria The function of ribosomal RNA (rRNA) is to A. Transfer an amino acid to the ribosome B. Carry the genetic information coded in DNA C. Copy the genetic code present in mRNA D. Form ribosomes, the sites of protein synthesis The function of messenger RNA (mRNA) is to A. Carry Amino Acids to the ribosome C. Translate the base sequence at the ribosomes B. Make a copy of the DNA instructions and bring it to the ribosome D. Prevent DNA mutations during replication The process by which DNA’s information is copied into RNA is called A. Transcription C. Synthesis B. Translation D. Polymerization Which of the following represents the codons that correspond to the segment TATCAGGAT of DNA? A. ATA-GTC-CTA B. TCA-CUG-GUA C. AUA-GUC-CUA D. ACA-CUC-GUA What is the name of the enzyme that initiates transcription? A. DNA Polymerase B. ATP Synthase C. RNA Polymerase D. Transformation principle Eukaryotic mRNA molecules are occasionally interspersed with noncoding sequences that must be removed before protein synthesis. These are ________. A. Introns B. Anticodons C. Nucleosomes D. Chromosomes What class of RNA binds free amino acids and carries them to ribosomes? A. tRNA B. rRNA C. mRNA D. None of them Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below. What type of mutation is depicted in this sequence? A. Insertion B. Substitution C. Deletion D. Frameshift Which of the following polypeptides is coded for by the mRNA sequence 5’ AUGGUUAAACGACAAUCC 3’? A. Val-lys-Phe-Gly-Ser B. Met-Val-Lys-Arg-Gln-Ser C. Met-Asp-Phe-Ala-Arg D. Ile-Gln-Lys-Asp-Gly-Leu-Ser Which cellular process takes place in the ribosomes that are bound to the endoplasmic reticulum? A. The synthesis of new proteins C. The conversion of radiant energy to glucose B. The breakdown of waste material D. The replication of nucleic acid A mutation is least likely to affect a cell when the mutation — A. Reverses the order of bases in a DNA strand C. Replaces a base with complementary base B. Produces a triplet that codes for the same amino acid as the original strand D. Allows the total number of bases in a DNA sequence to remain the same In 1917 the biologist Thomas Hunt Morgan conducted studies in which he kept some caterpillars in the dark and placed some others under red, green, or blue lights. Exposure to red light produced butterflies with brightly colored wings. Exposure to green light resulted in dark-colored wings. Exposure to blue light or no light resulted in pale-colored wings. What was the most likely conclusion of Morgan’s research? A. The pigment in butterfly wings absorbs light from the environment. B. The phenotypic expression of wing shape depends on color pigmentation in butterflies C. The genes regulating wing color in D. Caterpillars exposed to red and green light butterflies are influenced by environmental factors are healthier than caterpillars exposed to no light or blue light. The many different functions and behaviors of living organisms are essentially based on the performance of their cells. The cell’s performance in turn is dependent upon the A. Production of steroids and hormones C. Production of correct membranes B. Production of many varieties of polypeptides and proteins D. Ability to reproduce 50-50 Lifeline Slides During protein synthesis, the amino acid sequence is determined by the _________ B. Number of mitochondria in the cell D. Genetic code in the DNA molecule Synthesis of a defective protein may result from an alteration in the A. Cell’s Fat Concentration B. Base sequence code in DNA The function of ribosomal RNA (rRNA) is to A. Transfer an amino acid to the ribosome D. Form ribosomes, the sites of protein synthesis The function of messenger RNA (mRNA) is to A. Carry Amino Acids to the ribosome B. Make a copy of the DNA instructions and bring it to the ribosome The process by which DNA’s information is copied into RNA is called A. Transcription C. Synthesis Which of the following represents the codons that correspond to the segment TATCAGGAT of DNA? B. TCA-CUG-GUA C. AUA-GUC-CUA What is the name of the enzyme that initiates transcription? B. ATP Synthase C. RNA Polymerase Eukaryotic mRNA molecules are occasionally interspersed with noncoding sequences that must be removed before protein synthesis. These are ________. A. Introns D. Chromosomes What class of RNA binds free amino acids and carries them to ribosomes? A. tRNA C. mRNA Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below. What type of mutation is depicted in this sequence? B. Substitution D. Frameshift Which of the following polypeptides is coded for by the mRNA sequence 5’ AUGGUUAAACGACAAUCC 3’? B. Met-Val-Lys-Arg-Gln-Ser C. Met-Asp-Phe-Ala-Arg Which cellular process takes place in the ribosomes that are bound to the endoplasmic reticulum? A. The synthesis of new proteins D. The replication of nucleic acid A mutation is least likely to affect a cell when the mutation — B. Produces a triplet that codes for the same amino acid as the original strand C. Replaces a base with complementary base In 1917 the biologist Thomas Hunt Morgan conducted studies in which he kept some caterpillars in the dark and placed some others under red, green, or blue lights. Exposure to red light produced butterflies with brightly colored wings. Exposure to green light resulted in dark-colored wings. Exposure to blue light or no light resulted in pale-colored wings. What was the most likely conclusion of Morgan’s research? B. The phenotypic expression of wing shape depends on color pigmentation in butterflies C. The genes regulating wing color in butterflies are influenced by environmental factors The many different functions and behaviors of living organisms are essentially based on the performance of their cells. The cell’s performance in turn is dependent upon the B. Production of many varieties of polypeptides and proteins D. Ability to reproduce 100 200 300 500 1000 2000 4000 8000 16000 32000 32000 64000 125000 250000 500000 1000000 20 22 23 24 25 26 27 28 29 21 12 13 14 15 16 17 18 19 10 11 9876543210 30 0% 0% 0% 0% A B C D Fastest Finger slide to follow Correctly order the central Dogma A. DNA B. Protein C. mRNA D. Amino Acids A. DNA C. mRNA D. Amino Acid B. Protein “Who Wants To Be A Millionaire” Powerpoint (Advanced) Template Designed and Created by Jeff White jcteacher@yahoo.com Copyright © 2000 Version 2.1 - Last updated 20 June, 2001 The graphics and sounds used in this template are recorded from the television show “Who Wants To Be A Millionaire,” and were obtained from both the ABC “WWTBAM” website and the ITV “WWTBAM” website. ABC is the American Broadcasting Corporation; ITV is the Channel 3 (UK) broadcasting company. Visit http://www.geocities.com/jcteacher/tech/ for updated versions!