Name: THE NERVOUS SYSTEM: NEURONS Cell bodies of interneurons found in the human brain. You are born with approximately twice as many neurons as you have now. The die-off of neurons occurs early in life, and with more room, the remaining neurons make many connections with other existing neurons. The degree of interconnectedness apparently determines our intelligence and memory. It is estimated that the human brain contains 100 billion (1011) interneurons averaging 1000 synapses on each; that is, some 1014 connections. If you had 1014 pennies, how much money would you have? SVHS ADVANCED BIOLOGY ANATOMY AND PHYSIOLOGY UNIT #7 SPRING SEMESTER 2013 SVHS ADVANCED BIOLOGY 2012-2013 UNIT #7: NERVOUS SYSTEM - NEURONS OUTCOMES: A) B) C) D) E) F) G) H) Be able to explain how the body has two systems of communication; a fast nervous system and a slow endocrine system. (Page 225) Be able to describe how an impulse is created and why it moves along an axon or dendrite. (Pages 230-234) Be able to explain how the nervous system is composed of two types of cells; neurons and neuroglial cells. Explain the different types of neuroglial cells and their functions. (Pages 228-231) Be able to describe the structure of a typical neuron. (Pages 228-230) Be able to explain what saltatory conduction is and the role of the myelin sheath. (Pages 233) Be able to contrast an action potential and resting potential in terms of charges on the membranes and the ion concentrations. (Pages 230-234) Be able to explain how an impulse bridges the gap between two neurons. (Pages 235-237) Explain what factors determine if neurons can regenerate. (Page 230) Tuesday 1/8 Discussion: Lab: packet Homework: Introduction to Nervous System Activity A, begin Activity B Complete D.R. #9.1 Wednesday 1/9 Discussion: Lab: packet Homework: Structure of neurons. Complete Activity A and B Complete D.R. #9.2 Friday 1/11 Discussion: Lab: packet Homework: Conduction of nerve impulses. Activity C: Reaction time lab. (No caffeine) Complete D.R. #9.3 Tuesday 1/15 Discussion: Lab: packet Homework: Conduction of nerve impulses. (Cont.) Activity C: Reaction time lab (with caffeine). Study guide, work on data analysis Wednesday 1/16 Discussion: Conduction across a synapse & regeneration of nerve tissue Friday 1/18 Lab: Homework: Reaction Time Lab (with caffeine) Prepare lab write up, work on study guide, complete packet Monday 1/21 Martin Luther King Holiday Wednesday 1/23 Unit #7 Test: Nervous System: Neurons SVHS ADVANCED BIOLOGY UNIT #7: CENTRAL NERVOUS SYSTEM LAB ACTIVITIES PART “A”: Neuron Types. Label each type of neuron shown below. See notes regarding types of neurons. Describe where each type might be found. Explain how each type differs in structure. Neuron Type: Neuron Type: Neuron Type: Found: Found: Found: Differences: Differences: Differences: Explain what this picture might be showing. Label structures using arrows. Using page 229 of Tortora, label the structures of the neuron shown below. (Use each of the names listed in the table on the next page.) Identify the structures being pointed to in the diagram of the axon cross section. Below, briefly describe the role played by that structure. #1: #2: #3: #4: PART "B": OBSERVATION OF NEURONS FOUND IN THE SPINAL CORD. Using the sample of cow spinal cord diagram 3 neurons and their associated structures. Also diagram the neuroglial cells found in the sample. Label all structures observed. In the space below name and describe the role of the different types of neuroglial cells. Refer to page 208 of Tortora. Spinal Cord Neurons (400X) Structure of Neuron Cell Body Dendrite Axon Axon Collateral Axon Terminals Synaptic end bulbs Myelin Sheath Node of Ranvier Schwann Cell Function REACTION TIME EXPERIMENT. PART “C”: In this lab you will use a “reaction time ruler” to measure your lab partner’s reaction time. After a predetermined number of practice runs an average of ten trials will determine the reaction time. We will then compare a “caffeine” reaction time with a “non-caffeine” reaction time. Only willing participants who regularly use caffeine will be involved in the comparison portion of the lab. The procedure described below must be followed exactly as stated in order to get reliable results. TEST PROCEDURE: 1) The subject to be tested must sit in a chair. 2) The releaser stands facing the subject and holds the release end of the ruler at his/her eye level. 3) The subject positions the thumb and first finger over the “thumb line”. The distance between the thumb and the first finger should be 1inch. 4) when ready the subject tells the releaser to “start”. 5) Once told to start, the releaser must release the ruler within a 10 sec time frame. The releaser must not look at the subject until after the subject has caught the ruler. 6) The subject must catch the ruler as quickly as possible after the release. 7) The line under the middle of the subjects thumb is used to determine the reaction time. 8) After 10 practice trials the actual 10 test trials are performed. 9) Record each test result. Trial 1 2 3 4 5 6 7 8 9 10 Average Practice Test w/o caffeine Test with caffeine Unit #7: NERVOUS SYSTEM SELF STUDY GUIDE 1) From pages 225-230, be able to: A) B) C) D) E) Name the system that responds quickly and the system that responds slowly to the body’s needs. Name the three basic functions of the nervous system. Name the two types of cells found in the nervous system. Contrast neurons and neuroglial cells as to size, numbers, and types. Identify and give a function for the following structures of a neuron; cell body, axon, dendrite, axon collaterals, axon terminals, synaptic end bulbs, synaptic vesicles. F) Describe the structure and role of the myelin sheath. G) Contrast white and gray matter as to myelin sheath. 2) From pages 230-234, be able to: A) List two striking characteristics of neurons. B) Characterize a nerve impulse. C) Explain how ions play a role in creating an impulse. D) Explain how ion channels play a role in nerve impulses. E) Characterize a neuron that is resting regarding charges, ion concentrations. F) Explain the role of the sodium – potassium pump in a neuron. G) Explain what a resting potential means in terms of a neurons membrane. H) Explain when a neuron’s membrane said to be “polarized”. I) Explain what is meant by the term “excitability”. J) Explain what is meant by “depolarization” and “repolarization”. K) Explain the term “threshold” regarding a stimulus to a neuron’s membrane. L) Explain what happens when the “threshold’ is reached. M) Define “action potential”. N) Explain how the “refactory period” impacts the neuron. 3) From page 232-234, be able to; A) B) C) D) E) F) G) Define threshold stimulus. Explain the “all-or-none” principle. Explain how a sub-threshold stimulus is different compared to a threshold stimulus. Explain what is meant by the term “summation”. Define and contrast continuous and saltatory conduction. Describe three factors that determine the speed of the impulse along a neuron. Explain how size of the nerve fiber determines speed and which size is myelinated and which is not. 4) From pages 233-236 titled “Conduction Across a Synapse”, be able to; A) B) C) D) E) F) G) Explain what a synapse is and where it would be found. Contrast pre-synaptic and post-synaptic neurons. Explain the role of a neural transmitter. Describe the structure and role of synaptic vesicles. Explain how an impulse bridges a synapse. Explain why impulses can only travel in one direction. Explain the three possible results of a postsynaptic neuron receiving an impulse. 5) From page 230, be able to; A) Explain what types of neurons can regenerate themselves after injury. B) Explain what factors determine if a neuron will regenerate.