Nervous System Cells The Nervous System • The Nervous system is responsible for communication • Composed of the: • Brain • Spinal Cord • Nerves Organization of the Nervous System • Central Nervous System (CNS) • Brain • Spinal Cord • Peripheral Nervous System (PNS) • Cranial Nerves • Spinal Nerves Afferent and Efferent Divisions • Afferent Division – consists of all of the incoming sensory pathways • Efferent Division – Consists of all of the outgoing motor pathways Somatic and Autonomic Divisions • Somatic Nervous System (SNS) • Somatic Motor Division – carries information to the somatic effectors (skeletal muscles) • Somatic Sensory Division – carries feedback information to somatic integration centers in the CNS Autonomic Nervous System (ANS) • Efferent division of the ANS carries info to the autonomic or visceral effectors (smooth and cardiac muscle) • Sympathetic division – “fight-or-flight” response • Parasympathetic division – “rest-and-repair” division • Visceral Sensory division carries feedback info to autonomic integrating centers of the CNS Cells of the Nervous System • Neurons – excitable cells that conduct the impulses that make possible all nervous system functions • Glia – (glial cells) support the function of neurons in various ways Glia (Neuroglia) • 900 billion in the human nervous system • Retain their capacity for division (makes them susceptible to cancer) Astrocytes • Found only in the CNS • Largest and most numerous • Feed the neurons • “Blood-brain barrier” Microglia • Small, stationary cells found in the CNS • In inflamed tissue they enlarge and move about in order to carry out phagocytosis of microorganisms and cellular debris Ependymal Cells • Resemble epithelial cells • Form thin sheets that line the fluid cavities of the brain • Some secrete the fluid • Cilia to circulate fluid Oligodendrocytes • Cell with few branches • Help hold nerve fibers together • Produce the fatty myelin sheath around nerve fibers in the CNS Schwann Cells • Found only in the PNS • Functional equivalent of oligodendrocytes • Wrap around nerve fiber Nodes of Ranvier • Short space in the myelin sheath between adjacent Schwann cells Multiple Sclerosis Neurons • The human brain contains about 100 billion neurons • All neruons consist of a cell body and at least two processes–an axon and a dendrite Structural Classification of Neurons • Multipolar – have only one axon but several dendrites • Bipolar – have only one axon and only one highly branched dendrite • Unipolar – have only a single process extending from the cell body Structural Classification Functional Classification • Neurons can be classified according to the direction in which they conduct impulses • Afferent neurons – transmit to the spinal cord or brain • Efferent neurons – transmit away from the brain or spinal cord • Interneurons – conduct impulses toward motor neurons (entirely within the CNS) Reflex Arc Nerves and Tracts • Nerves are bundles of peripheral nerve fibers held together by several layers of connective tissue • Endoneurium – surrounds each nerve fiber • Perineurium – surrounds each fascicle • Epineurium – surround the nerve • In the CNS bundles of nerve fibers are called tracts Nerve Structure