Understanding Uncertainty Definitions and Tools for Risk Analysts Copyright © 2004 David M. Hassenzahl Goals for this Lecture • Understand sources and types of uncertainty • Evaluate quantitative and qualitative representations of uncertainty – Distributional forms • Explore some typologies • Consider how people interpret uncertainty Copyright © 2004 David M. Hassenzahl Overview • Uncertainty is unavoidable • Uncertainty is information! – Where to do further research – Worst case scenarios • Uncertainty is chronically understated – Generally satisfied with statistical analysis – Henrion and Fischhoff (1986), estimates of speed of light (see Kammen and Hassenzahl 1999 page 125) Copyright © 2004 David M. Hassenzahl Measured speed of light (km/sec) 300000 299830 Expected value with standard error 299950 299820 Recommended value with reported uncertainty 299900 299810 299850 299800 299800 299790 299750 299780 299700 299770 299650 299760 299600 1870 299750 1900 1880 1890 1900 Year of experiment 1984 value 1910 1920 1930 1940 1950 Year of experiment From Henrion and Fischhoff Copyright © 2004 David M. Hassenzahl (1986) 1960 1970 Some thoughts • “Research efforts in risk analysis should be viewed as tools for understanding uncertainties, not necessarily for reducing them.” (Finkel, 1990) • “Probability does not exist” (Morgan and Henrion, 1990) – Either you die from cause X or you don’t Copyright © 2004 David M. Hassenzahl Uncertainty Analysis Should Be Thorough • It should include quantitative measures of uncertainty • It should include qualitative discussion of uncertainty • Doing this well takes time and effort (and is not always rewarded…) Copyright © 2004 David M. Hassenzahl Quantitative Measures • Display the data set • Use descriptive statistics – Moments, ranges, etc • Apply sensitivity analysis • Eschew spurious precision! Copyright © 2004 David M. Hassenzahl Use of Point Estimates? • “introducing confidence intervals…to deal with uncertainty may be pointless…unless the policy analyst eliminates the point estimate itself.” • “A specific number has a vividness and simplicity which makes it an inevitable focus of policy debate.” • Camerer and Kunreuther, 1989 Copyright © 2004 David M. Hassenzahl Point Estimate or not? +100% increas e Change in risk 0 reduction -100% do nothing 1 2 3 Option Figure 10-6 from SWRI page 258 Copyright © 2004 David M. Hassenzahl 4 5 Qualitative discussion • Discuss known sources of error • Consider plausible sources of error • Evaluate the importance of uncertainty Copyright © 2004 David M. Hassenzahl Challenges to ignoring uncertainty • Regarding a report on ozone depletion “…no attempt was made to estimate the systematic errors in evaluating rates or omission of chemical processes. Without such estimates, decision makers are free to make their own judgments ranging from uncritical acceptance of the current models to complete skepticism as to their having any likelihood of being correct.” Morgan and Henrion 1990. Copyright © 2004 David M. Hassenzahl Historical Mistakes • Rasmussen Report (WASH 1400) on reactor safety – Significant portions retracted by US government – Still referenced • Inhaber report on nuclear “safer” than other energy technologies – Major source (Holdren) responded “not so” • Chauncy Starr – Voluntary/involuntary – Risk as f(benefit) – True…but not precisely known • Tengs et al? Copyright © 2004 David M. Hassenzahl Briggs and Sculpher (1995) • Cost-effectiveness analyses from medical literature – Public Health origins of CEA • Incomplete or inadequate attention to uncertainty analysis in 86% Copyright © 2004 David M. Hassenzahl Starr (1969) interpretation -3 10 -4 -5 -6 10 -7 10 -8 -9 10 -10 Pf [Fatalities/person hr. exposure] 10 10 Voluntary General aviation R~B3 10 10 Hunting, skiing, smoking Railroads Commercial aviation Motor vehicles Involuntary R~B3 Electric power 10 R = Risk B = Benefit Natural disasters 10 100 Average P f due to disease -11 200 500 1000 2000 5000 Average annual benefit/person involved [dollars] Copyright © 2004 David M. Hassenzahl 10000 Otway and Cohen (1975) Interpretation -3 10 -4 -5 -6 Pf [Fatalities/person hr. exposure] 10 R~B1.8 General aviation 10 10 10 -7 10 -8 -9 10 -10 Hunting, skiing, smoking Commercial aviation Motor vehicles Voluntary Average P f due to disease Railroads Involuntary R~B6.3 Electric power 10 R = Risk B = Benefit Natural disasters 10 100 -11 200 2000 500 1000 5000 Average annual benefit/person involved [dollars] Copyright © 2004 David M. Hassenzahl 10000 Example: Amitraz on Pear Orchards • EPA decided to ban Amitraz for use on pear orchards (US EPA 1979) • Point estimate generated for Cost effectiveness – $2.6 million per life-year saved (Tengs et al 1995) Copyright © 2004 David M. Hassenzahl Expected Value of Ban • Does Amitraz control pests? – If not, ban has no economic implications – cpyls ≤ $0 • Is Amitraz a carcinogen? – If not, ban has major economic implications – cpyls $ ∞ • E(cpyls) ≠ $2.6 million • E(cpyls) = uniform($0, $∞) • Hassenzahl (2004) Copyright © 2004 David M. Hassenzahl Estimators • Because we can’t always get the data we want, we need to estimate data • We can use – Frequencies – Distributions – Curve-fitting Copyright © 2004 David M. Hassenzahl Frequency example: 500 people • • • • • • 495 have 10 toes 2 have 12 toes 1 has 9 toes 1 has 5 toes 1 has 0 toes In next 1000: how many will have 6 toes? Copyright © 2004 David M. Hassenzahl Distributions as estimators • We often use DISTRIBUTIONAL FORMS to approximate data sets • We then estimate missing or future values using the distribution – Extrapolate beyond data set – Interpolate within data set Copyright © 2004 David M. Hassenzahl Example: 500 people • • • • • • • • • feet 0 0.5 1 1.5 2 2.5 3 3.5 number 0 0 0 0 0 0 1 1 • • • • • • • • • feet 4 4.5 5 5.5 6 6.5 7 7.5 Copyright © 2004 David M. Hassenzahl number 12 48 145 203 78 10 2 0 Triangular? Normal? 0.45 0.4 0.35 Frequency 0.3 0.25 0.2 0.15 0.1 0.05 0 -0.05 0 1 2 3 4 5 6 Height (feet) Copyright © 2004 David M. Hassenzahl 7 8 9 Normal: Characteristics: Mean = 5.6 feet, Standard Deviation = 1.3 feet Forecast: Normal 10,000 Trials Frequency Chart 9,921 Displayed .022 218 .016 163.5 .011 109 .005 54.5 .000 0 2.21 3.89 5.58 7.27 Copyright © 2004 David M. Hassenzahl 8.96 Triangular? Normal? 0.45 0.4 0.35 Frequency 0.3 0.25 0.2 0.15 0.1 0.05 0 -0.05 0 1 2 3 4 5 6 Height (feet) Copyright © 2004 David M. Hassenzahl 7 8 9 Triangular? Normal? 0.45 0.4 0.35 Frequency 0.3 0.25 0.2 0.15 0.1 0.05 0 -0.05 0 1 2 3 4 5 6 Height (feet) Copyright © 2004 David M. Hassenzahl 7 8 9 A Good Estimator Is • • • • • • Consistent Unbiased Efficient Sufficient Robust Practical Copyright © 2004 David M. Hassenzahl Depicting Uncertainty: Distributions • No consensus on how to depict ignorance! – More later under Monte Carlo Analysis • Key forms – Uniform / rectangular – Triangular – Normal, lognormal – Many others! Copyright © 2004 David M. Hassenzahl Decision • When should we hold the Founder’s Day parade? • Assume we want to avoid tornadoes Copyright © 2004 David M. Hassenzahl Kammen and Hassenzahl 1999 Uniform Probability of tornado 0.003 0.002 0.001 Jan Feb M ar Apr M ay Jun Jul Aug Sep Oct Nov Month From SWRI page 106. Figure 3.5 Uniform distribution for daily p(tornado) as described in problem 3-7a. Copyright © 2004 David M. Hassenzahl Dec Kammen and Hassenzahl 1999 Rectangular Probability of tornado 0.012 0.010 0.008 0.006 0.004 0.002 Jan Feb M ar Apr M ay Jun Jul Aug Sep Oct Nov Month From SWRI page 106. Figure 3-6 Rectangular distribution for daily p(tornado) as described in problem 3-7a. Copyright © 2004 David M. Hassenzahl Dec Kammen and Hassenzahl 1999 Triangular Probability of tornado 0.025 0.020 0.015 0.010 0.005 0 Jun Jul Aug Sep Month From SWRI page 107. Figure 3-7 Triangular distribution for daily p(tornado) as described in problem 3-7a. Copyright © 2004 David M. Hassenzahl Oct Policy Decision • Radon is found in homes across the country • We might worry at 100 pCi/liter • We can’t measure all the homes in the country, but we have a decent sized sample • It matters how we model that distribution Copyright © 2004 David M. Hassenzahl Normal Distribution Number of homes 1 4 1 2 1 0 8 6 4 2 0 0 1 2 3 4 5 Radon level (pCi/liter) Kammen and Hassenzahl 1999 Copyright © 2004 David M. Hassenzahl 6 7 8 Lognormal 20 Houses (%) 15 10 5 >8 0 0 Nero et al 1987 2 4 222Rn 6 (pCi/liter) Copyright © 2004 David M. Hassenzahl 8 Exponential % of houses with concentration > x 100 USAless6 pwr(1.25) % 10 pwr(1.75) % LnNrm3.5% 1 0.1 0.01 0.001 0.0001 1 10 Goble and Socolow 1990 100 Rn Concentration Copyright © 2004 David M. Hassenzahl 1000 Fitting distributions to data sets • Compare data to predictions – Least squares – Maximum Likelihood • We will explore these in context – Binomial for animal toxicology data Copyright © 2004 David M. Hassenzahl Breaking Down Uncertainty • Useful typologies for thinking about uncertainty • Can’t always reduce uncertainty • Typologies have – Internal overlaps – Missing pieces (no perfect typology) Copyright © 2004 David M. Hassenzahl Four typologies • Finkel • Boholm – Parameter Uncertainty – Model Uncertainty – Decision-rule Uncertainty • Smithson – non-quantifiable/holistic aspects – uncertainty as one component of ignorance.” – Situates Uncertainty as the noncalculable part of risk – appropriate coping strategies: • faith • precaution and • avoidance Copyright © 2004 David M. Hassenzahl Typology (after Morgan and Henrion 1990) 1. Random error and statistical variation 2. Systematic error and subjective judgment 3. Linguistic imprecision 4. Variability 5. Randomness and unpredictability 6. Expert Uncertainty 7. Approximation 8. Model uncertainty Normative Uncertainty Copyright © 2004 David M. Hassenzahl Random error/statistical variation • We have a well defined set of tools • These can be misleading! – Often the ONLY thing that is done – Often done…and ignored • Z-scores, Chi-squared, p-values • Meaning of 95% confidence interval? Copyright © 2004 David M. Hassenzahl Random Error: “Clusters” Copyright © 2004 David M. Hassenzahl Systematic error and subjective judgment • Example: speed of light, or energy predictions • Chronically understated • Useful approach: bounding Copyright © 2004 David M. Hassenzahl Systematic Error: Predicted Year 2000 Energy Use 200 Quadrillion Btu Per Year 175 150 125 100 75 50 25 0 1972 1974 Goldemberg et al 1987 1976 1978 1980 Year of Publication Copyright © 2004 David M. Hassenzahl 1982 Linguistic imprecision • Inconsistencies in language and usage can lead to problems • Is “beyond a reasonable doubt” 95%? What does that mean? • “Rain is likely”…are you from Las Vegas or Bangladesh? • “A few thousand deaths” Copyright © 2004 David M. Hassenzahl Variability • • • • Also called “dispersion” Get the right population! Describing variability can be a challenge Monte Carlo analysis is a useful tool Copyright © 2004 David M. Hassenzahl Variability • Height of individuals – Deterministic element – Random element • Susceptibility to disease – Predisposition • Known • Unknown • Theoretical models • Empirical data • Who are we worried about? – “Average” person – Most susceptible subset – Life-history and habit Copyright © 2004 David M. Hassenzahl Randomness and unpredictability • Inherent randomness is irreducible! • Practical limitations and chaos Copyright © 2004 David M. Hassenzahl Expert uncertainty • Multiple interpretations of a single data set • Norms of analysis • Motivational bias (decision stakes, reputation) Copyright © 2004 David M. Hassenzahl Expert Uncertainty • Economists’ Conception – Limited resources – Resource substitution – Adaptability • Ecologists’ Conception – Stable systems – Long term impact of disruption Copyright © 2004 David M. Hassenzahl Climate Change: Economists “versus” Ecologists 25 90th percentile 50th percentile Loss of gross world product 20 10th percentile 15 10 5 0 -5 14 17 3 16 1 2 9 4 11 6 15 12 18 7 13 10 5 8 Individual respondents' answers Nordhaus 1994 Copyright © 2004 David M. Hassenzahl EMF’s and Expertise • Biomechanists / physicists – “Impossibility” theorems • Epidemiologists – Correlation and proposed causation • Toxicologists – Extrapolation Copyright © 2004 David M. Hassenzahl Approximation • Never have complete data • There is a tradeoff between efficient computation and resolution or precision – Sensitivity analysis • Significant figures are important Copyright © 2004 David M. Hassenzahl Model uncertainty • Getting the right model – Does the model explain the data? – Is the model consistent with theory? • Getting the model right – Is the model properly stated? – Is the math done correctly • Other uncertainties (drawn from the typology above) Copyright © 2004 David M. Hassenzahl Model Uncertainty % of houses with concentration > x 100 USAless6 pwr(1.25) % 10 pwr(1.75) % LnNrm3.5% 1 0.1 0.01 0.001 0.0001 1 10 Goble and Socolow 1990 100 Rn Concentration Copyright © 2004 David M. Hassenzahl 1000 Normative Uncertainty • Often not asked: what is important to us? • Arguments about technical information mask the true issues • Leads to vitriol and claim of “ignorance” and “antiscientific attitudes” Copyright © 2004 David M. Hassenzahl Normative UC and YMP • Gore, Bush: “let the science decide” • Secretary Abraham “technically suitable site” • LV residents “technically unsuitable site” • Have we defined “suitability?” Copyright © 2004 David M. Hassenzahl Interpreting Uncertainty • Very limited information on how people interpret uncertainty • Possible links – Uncertainty and credibility – Uncertainty and trust Copyright © 2004 David M. Hassenzahl References • Briggs, A. and M. Sculpher (1995) Sensitivity analysis in economic evaluation: a review of published studies. Health Economics 4: 355-371. • Camerer, C. F. and Kunreuther, H. (1989) “Decision Processes for Low Probability Events: Policy Implications,” J. Policy Analysis and Management 8 (4), 565 - 592. • Goble, R. and Socolow, R. (1990), “High Radon Houses: Implications for Epidemiology and Risk Assessment,” Cented Research Report No. 5 (Clark University, Worcester, MA). Copyright © 2004 David M. Hassenzahl References • Goldemberg, J,. Johansson, T., Reddy, A and Williams, R (1987). Energy for a Sustainable World. Washington DC: World Resources Institute. • Hassenzahl, D. M. (2004). “The effect of uncertainty on ‘risk rationalizing’ decisions.” Journal of Risk Research. • Henrion, Max and Fischhoff, Baruch (1986) “Assessing uncertainty in physical constants”, American J. of Physics,54, 791 - 798. Copyright © 2004 David M. Hassenzahl References • Nero, A. V., Schwehr, M. B., Nazaroff, W.W. and Revzan, K.L. (1986) “Distribution of Airborne Radon222 Concentrations in U.S. Homes,” Science (234) 992 - 997. • Nordhaus, W. D. (1994) “Expert opinion on climate change”, American Scientist, 82, 45 - 51. • Otway, H. and J. J. Cohen (1975). Revealed Preferences: Comments on the Starr Benefit-Risk Relationships. Laxenburg, Austria, International Institute for Applied Systems Analysis. Copyright © 2004 David M. Hassenzahl References • Starr, C. (1969). "Social benefit versus techological risk." Science 165: 1232-1238. • Tengs, T. O., M. E. Adams, et al. (1995). "Five-Hundred Life-Saving Interventions and Their Cost-Effectiveness." Risk Analysis 15(3): 369 - 390. • US EPA (1979) Determination pursuant to 40CFR162.11(a)(5) concluding the rebuttable presumption against registration of pesticide products containing amitraz. Federal Register 48: 2678-83. Copyright © 2004 David M. Hassenzahl Additional readings • Kammen and Hassenzahl, 1999. Should We Risk It? Exploring Environmental, Health and Technology Problem Solving, Princeton University Press, Princeton NJ. • Finkel, Adam, 1990. Confronting Uncertainty in Risk Management (Resources for the Future, Washington DC) • Morgan, M. Granger and Max Henrion (1990). Uncertainty Cambridge University Press, NY NY. Copyright © 2004 David M. Hassenzahl