Using r and 2 Statistics for Risk Analysis Copyright 2002 David M. Hassenzahl Objectives • Purpose: to compare model to data – “validate model” (or not) • Two techniques – r (correlation coefficient) – 2 (Chi-squared) • Apply to a familiar problem (barium decay) Copyright 2002 David M. Hassenzahl Statistics • Descriptive • Comparison – Z-scores, hypotheses – Confidence levels – Evaluating models – Correlation and Chi-squared Copyright 2002 David M. Hassenzahl Confidence Levels • Given 100 flips of a coin. Would you bet $1000 that the next flip will yield heads if – – – – 50 heads? 90 heads? 99 heads? 999 heads out of the last 1000 flips? • How about for $5? For 50% of your current net worth? Copyright 2002 David M. Hassenzahl Statistical Significance • Z= – (sample occurrence – number in sample times expected probability – Divide by square root of (np(1-p) • • • • Student’s t One-sided versus two sided tests! “p values” Confidence intervals Copyright 2002 David M. Hassenzahl Type I and II errors • Type I: reject the truth! (accuracy) • Type II: accept an untruth! (precision) • This is important… there’s often a tradeoff here! Copyright 2002 David M. Hassenzahl Z-scores Intuition x μ0 Z s n • Z score will be big if – Numerator: if xbar >> OR >> xbar – s is very small – n is very big • Bigger Z-score: confidence that xbar • Small Z-score: confidence that xbar Copyright 2002 David M. Hassenzahl From Z’s to r’s and 2 • r and 2 compare more than one estimate • Compare – Set of model predictions to – Set of data or observations • If r is SMALL (little correlation) the model doesn’t fit • If 2 is SMALL then the model does fit Copyright 2002 David M. Hassenzahl “Goodness of fit” • We say that r and 2 evaluate “goodness of fit” • Note that a good fit does not mean that the model is right! Copyright 2002 David M. Hassenzahl Barium Decay • Theory: barium is removed as a constant function of concentration • “Exponential decay” • C(T) = C(0)ekT – k = -0.007/min – C(0) = 0.16 mgBa / liter blood • (From SWRI page 56 – 63; hypothetical) Copyright 2002 David M. Hassenzahl Exponential Decay Model 0.16 Blood barium concentration (mg/l) 0.12 0.08 0.04 0 0 60 120 180 240 300 360 420 time Figure 2-9 from Should We Risk It? Copyright 2002 David M. Hassenzahl Sample blood at 1 hour intervals Time (hours) 0 1 2 3 4 5 6 7 8 Measured Concentration 0.16 0.13 0.087 0.055 0.040 0.022 0.009 0.002 Copyright 2002 0.001 David M. Hassenzahl Measured and Expected Time (hours) 0 1 2 3 4 5 6 7 8 Measured Concentration 0.16 0.13 0.087 0.055 0.040 0.022 0.009 0.002 0.001 Predicted Concentration 0.16 0.11 0.070 0.045 0.030 0.020 0.013 0.0095 2002 0.0056David Copyright M. Hassenzahl Graphical Comparison 0.16 Blood barium concentration (mg/l) 0.12 0.08 0.04 0 0 60 120 180 240 300 360 420 time After Figure 2-9 from Should We Risk It? Copyright 2002 David M. Hassenzahl How well does the model fit? • Why do we care? – Future predictions – Is there a better model? • Looks OK. Is that good enough? • Try our two tools: r and 2 Copyright 2002 David M. Hassenzahl r Conceptual • Compares model predictions to the data • Asks – “What if there is no relationship (or correlation) between model and data?” – Is the model as close to the average value of the x’s as it is to the actual x’s? Copyright 2002 David M. Hassenzahl r terms or components • Predicted mean and standard deviation • Observed mean and standard deviation • “Covariance” – Do they go up and down together? – If independent, covariance = 0 • r = Covariance (predicted, observed) (STDEV O) (STDEV P) Copyright 2002 David M. Hassenzahl Means • Observed xobar = ( xoi) /n • xobar = (0.16+0.13+0.087+0.055+0.040 +0.022+0.009+0.002+0.000)/9 = 0.056 • Observed xpbar = ( xpi) /n = 0.051 Copyright 2002 David M. Hassenzahl Standard Deviations so 1 x n 1 o xoi 0.056 sp 1 x n 1 p x pi 0.051 2 2 Copyright 2002 David M. Hassenzahl Covariance Covo, p 1 x n 1 o xoi x p x pi Copyright 2002 David M. Hassenzahl Calculated r • r = Covariance (predicted, observed) (STDEV O) (STDEV P) cov p , o r 0.99 so sp Copyright 2002 David M. Hassenzahl Intuition Behind r • If there is no relationship between observed and predicted, r = 0 • If r 0, positive correlation • If r 0, negative correlation Copyright 2002 David M. Hassenzahl r Discussed • • • • 0.99 seems reasonably good Is there a better fit What about theory? Limitations: even low correlations may be okay…just a screening tool Copyright 2002 David M. Hassenzahl t test for r • n-2 = 7 degrees of freedom • Look it up in the Student’s-t table • Accept model validity at 99% confidence level if Student’s t is greater than 2.998 t r n2 1 r 2 Copyright 2002 David M. Hassenzahl Chi-squared n χ 2 i 1 x x pi 2 oi x pi • This formula “normalizes” to the size of the individual xoi • If all xoi xip, 2 = 0 • Look up value in table (page 398) Copyright 2002 David M. Hassenzahl Chi-squared • 9 data points • Suppose we are concerned with 99% confidence level • We would need a chi-squared of greater than 21.7 to reject this line • Calculating, we find that 2 = 0.06! • Note that it still might be possible to find a better line, even with the exponential Copyright 2002 David M. Hassenzahl Conclusion • Both r and Chi-squared appear to validate this model • Suggests that our theoretical idea about the model may be valid • Doesn’t tell us we are right, just that we may be acceptably wrong! Copyright 2002 David M. Hassenzahl