Inquiry Project Genetics & Heredity SCE 572 (01) Karen Daddona Jon DeMeglio Darryl Nicholson Janine Walsh Content: What will be modified/added/eliminated from the existing unit? For over two decades the foundation for state K-12 science standards has been based upon both the National Science Education Standards and the Benchmarks for Science Literacy. In the summer of 2011, the National Research Council unveiled the Framework for K-12 Science Education: Practices, Crosscutting Concepts and Core Ideas. The Framework presents, “key scientific ideas and practices” all students should learn by the end of grade 12. The objectives set forth by the Framework creators, the Committee on a Conceptual Framework for New Science Education Standards, are for all science learners: to have some appreciation of the beauty and wonder of science, possess sufficient knowledge of science and engineering to engage public discussions on related issues; are careful consumers of scientific and technological information related to their everyday lives; are able to continue to learn about science outside school; and to have the skills to enter careers of their choice, including careers in science, engineering, and technology. (NRC 1) Yes, this Framework will provide a new foundation for science education standards, as it replaces the previously established standards with the Next Generation Science Standards (NGSS), but how does it compare to present Life Science grades 6-8 content standards? As with any well developed course framework, both the Framework for K-12 Science Education and the Connecticut Prekindergarten–Grade 8 Science Curriculum Standards, present curriculum developers with critical information important to unit planning. Each framework provides an overview of the life science standards by outlining each unit topic that make up the course, as well as, addressing major concepts in each unit; both with a grade 8 endpoint band. When comparing the Framework and CT Standards side by side they are quite comparable with a few noted differences. Case in point, Framework Core Idea LS3: Heredity: Inheritance and Variation of Traits are comparable to CT Standard 8.2a with key concept word differences, with the addition of the terms allele and mutation referenced in the Framework. However, it should be noted that CT Standard 8.2.b. - Some of the characteristics of an organism are inherited and some result from interactions with the environment, is not directly comparable to the new Framework. Although both the Framework and the CT Standards focus on how characteristics are inherited by way of sexual reproduction, the CT Standards invite science instructors to explore how environmental conditions like “eating and exercising habits” are exhibited in human traits, while the Framework calls for teachers to concentrate more on human trait variation via mutations. New Generation Science Standards Compared to Current Standards Essential Question How are characteristics of one generation related to the previous generation? Why do individuals of the same species vary in how they look, function and behave? Framework for K-12 Science Education: Practices, Crosscutting Concepts & Core Ideas July 2011 Core Idea LS3: Heredity: Inheritance and Variation of Traits LS3.A: Inheritance of Traits LS3.B: Variation of Traits Connecticut Pre K -8 Science Curriculum Standards Including Grade-Level Expectations March 2009 Comparison Notes 8.2.a. Heredity is the passage of genetic information from one generation to another. Comparable with the exception that CT does not mention mutations. 8.2.a. Heredity is the passage of genetic information from one generation to another. Comparable with the addition that the Framework uses the term allele. TimeLine: What is the sequence of the teaching/learning activities? Essential Question: Day/s 1-3 Lesson Objectives: 4 5 What processes are responsible for life’s unity and diversity? Students will describe human traits. Students will distinguish between single gene and polygenic traits. Students will use tables to organize data and create histograms to graphically represent data. Students will identify patterns in data and draw conclusions from those patterns. The students will understand the role of probability in genetics. The students will be able to perform theoretical genetic crosses through the construction and use of Punnett Squares. The students will be able to apply probability principles to genetic crosses. The students will be able to determine phenotypes and genotypes using Punnett Square crosses. Students will learn important terminology used to explain inheritance. Students will explain the relationship between genotype and phenotype. Students will explain the inheritance of single gene traits using dominant/recessive relationships. Students will take genotype information from two parents, model the creation of gametes by independent assortment, and use those gametes to create offspring. Students will see that Mendel’s experiments demonstrate how characteristics are transferred from parent to offspring. Students will determine the appearance of their child’s face. Student will determine the bits of information that will contribute to the complete appearance of the child’s face by flipping coins Key Words Characteristic Trait Gene Polygenic Histogram Probability Punnett square Phenotype Genotype Allele Dominant Recessive Incomplete dominance Homozygous Heterozygous Gamete Zygote Teaching/ Learning Activity Human Traits In this activity, students will survey themselves and others for a wide array of traits. Dare to be Punnett Square This lesson familiarizes the students with Punnett squares, specifically purpose, application and interpretation. Making Babies This is an extension of the Human Traits survey activity designed to introduce students to genes, genotypes, and simple inheritance patterns. Day/s 6 Lesson Objectives: 7 8 9-10 Students will extract DNA. Students will recognize that DNA is found in all cells. Students will explain the steps needed to isolate DNA from a cell. Students will begin to describe the structure of DNA – that it is a long, invisibly thin polymer. Students will discover how codes work by reading and writing secret messages written in Morse code. Students will make up their own secret codes and trade messages written in their self-created code. Students will learn how DNA codes for a “secret” protein message in a two step coding system – the genetic code. Students will model and describe the general structure of DNA. Students will apply base pairing rules to assemble a DNA molecule. Students will infer that the sequence of the nucleic acids in DNA is the key to how DNA provides instructions to the cell. Students will relate this DNA puzzle activity to Franklin, Watson and Crick’s original discovery of the structure of DNA Students will discover the link between meiosis and the work of Mendel in genetics. Key Words DNA Nucleus Cell Membrane DNA Amino acids Protein Codon Morse code Genetic code DNA double helix base pairing mitosis meiosis Teaching/ Learning Activity DNA Extraction In this activity, students extract DNA from strawberries using diluted dish soap and alcohol. Secret Codes Have Your DNA and Eat It Too Students build an edible model of DNA while learning basic DNA structure and the rules for base pairing. Chromosomes of a Frimpanzee Practices: How will hands on (inquiry) activities be incorporated/changed? As we prepare to teach within the new Framework standards, it has become apparent that there is a clear overlap between the instructional strategies presented within the Process Skills, Core Scientific Inquiry Performances, Framework Scientific/Engineering Practices and the current trend of utilizing the 7-E Learning/Teaching Cycle. With the 7-E Instructional Model operating within the current CT Inquiry Expected Performances as well as the newly released Framework, it permits teachers to extend beyond lesson planning and development allowing for the broadening of unit study incorporating not only current scientific practices, but incorporating newly added engineering practices. Within the realm of genetics and heredity, science educators can “expand” the unit of study into biotechnology with discussion of genetically modified foods and eugenics. Units can be further developed to incorporate genetic technology opening dialogue of the Human Genome Project, stem cell research, cloning and gene therapy, which naturally lends itself to debate of bioethics and other social issues. The understanding of DNA allows for inquiry based activities in forensic investigation, DNA fingerprinting and human genetics disorders to name a few. As the Framework states, integrating engineering practices along with scientific practices will encourage students not only to ask questions of genetics, but define problems within the unit of study. In addition students will not only see how scientists construct explanations, but how engineers design solutions. Interdisciplinary Activities: Is there an integration component? The unit on genetics and DNA incorporates several other subjects for the interdisciplinary activities. The interdisciplinary integrated unit in Math will allow the teacher to do a couple of activities. The first activity entitled: Overview: How Punnett Squares May Be Used as a Mathematical Tool will focus on the use of ratios, proportions and percent to solve problems. Students will be able to calculate ratios and probability of each outcome and represent each outcome as a decimal, percent and fraction. The other activity will be: Solving Real World Problems through Math and Science. Students will be able to identify graphs, slope of graphs, and dependent and independent variables. The history teacher will incorporate a DNA Genealogy Timeline into their classroom. Students will be able to pin point significant findings in the history of genetics. The language arts section will allow students to create a comic strip using the Protein synthesis comic strip assessment. This will reinforce and assess students’ understanding of the central dogma of molecular biology. The students will also read The Disagreement of Mitosis and Meiosis by Corey E. Nagle. Students will learn about the basics of cellular division for producing body cells and gamete cells. Assessment: Formative and Summative Summative assessment is used to test a student’s knowledge for a given period. Usually this type of assessment is used to measure how much a student has learned up to a particular point in time. We see this type of assessment in our graded tests and quizzes. Homework can also be used if we use it as a grading tool. Summative assessment is what some call "assessment of learning" and what we as teachers use to see whether our students are meeting standards set by the state, the district, and the teacher. These assessments are conducted after a unit or certain time period to determine how much learning has taken place. But there are other ways to assess students. Formative assessments should be ongoing, repetitive measures designed to provide information to both the student and the teacher concerning students' understanding of small segments of course material. As an integrated approach to assessment and instruction, formative assessments emphasize mastery of course material as opposed to evaluation of performance or assignment of grades. Formative assessments are conducted throughout the instructional process to monitor students' progress and provide feedback on strengths and weaknesses. The key to formative assessment is the role of feedback; this feedback allows students to correct conceptual errors and encourages instructors to modify instructional activities in light of their effectiveness. Since formative assessments are designed to guide learning and are not utilized as an outcome measure, they are generally considered a low stakes assessment. Below are some examples of common formative assessment techniques. By no means is this list exhaustive. 1. Cooperating Teacher 2. Homework, Quizzes, and Tests 3. Exit Tickets 4. One-Minute Papers 5. Concept Mapping 6. Problem Solving Observation 7. Survey Students 8. Using feedback from students 9. Engage students in the process 10. See your teaching through your students' eyes 11. Identify Misconceptions 12. Photocopying, Saving, Reflection Tips Modification: What learning modifications are incorporated? An important baseline when developing and structuring science lesson plans that incorporate all learning styles is to first create a supportive surrounding environment. In a science class especially, a classroom environment should be set up in a way to provide a natural engagement feel in order to set the tone for great learning to take place. Lesson plans should then incorporate a variety of experiences that include different activities and opportunities to utilize the range of learning styles. Science is often an easy unit of study to access the different visual, motor, and auditory learning styles. Visual students can be engaged by performing experiments or providing pictures. Classroom experiments and group work is an excellent strategy to engage motor/kinesthetic learners. Planning lessons that incorporate a wide range of learning styles is most likely to produce a group of enthusiastic and engaged learners, which is any educator’s ultimate goal. Differentiated instruction in a science classroom can also be a beneficial learning modification. The technique advocates that the educator proactively plans a variety of instruction methods so as to best facilitate effective learning experiences which are suited to the various learning needs within the student. Continued adaptation to learners’ needs based upon constant assessment of all students. Differentiated instruction requires teachers to tailor their instruction and adjust the curriculum to students’ needs rather than expecting students to modify themselves to fit the curriculum. An important pre-assessment is imperative in this process. The goal is to continually acknowledge and aid in how a student shows they are mastering classroom concepts. References: Bopp, G. (2010). DNA Genealogy Timeline. Retrieved April 13, 2012, from http://freepages.genealogy.rootsweb.ancestry.com/~gkbopp/DNA/DNAtimeline.htm Connecticut State Department of Education. (March2009). Connecticut Prekindergarten–Grade 8 Science Curriculum Standards Including Grade-Level Expectations. National Research Council. (2012). A Framework for K-12 Science Education: Practices, Crosscutting Concepts, and Core Ideas. Washington DC: The National Academies Press. Nagel, C. (2012). The disagreement of mitosis and meiosis. Wilshire Press Inc. Retrieved April17, 2012, from http://www.thebookpatch.com/BookStoreDetails.aspx?BookID=5556&ID=c7447c61-3ca3-4f95b0eb-cdfd7ce28543 North Carolina State University. (2007). Exploring genetics across the middle school science and math curriculum. Retrieved April 12, 2012, from http://bonaire.cshl.edu/plantrep/ppt/ExploringGenetics.pdf Pratt, H. (2012). The NSTA Reader's Guide tp A FRAMEOWRK FOR K-12 SCIENCE EDUCATION: PRACTICES, CROSSCUTTING CONCEPTS, and CORE IDEAS. Arlington: NSTA Press. Salter. I. (n.d). My Science Box. Retrieved April 17, 2012, from http://www.mysciencebox.org/comicstrip Salter, I. (n.d.). My Science Box. Retrieved April 11, 2012, from http://www.mysciencebox.org/geneticsbox The University of Utah. (2012). Teach.Genetics. Retrieved April 12, 2012, from http://teach.genetics.utah.edu/content/begin/dna/eat_DNA.html Wang, B., & Leon, E. (2011, September 9). UCLA, GK-12 Science & Mathematics in Los Angeles Urban Schools. Retrieved March 2012, from The Chromosomes of a Frimpanzee: http://www.nslc.ucla.edu/STEP/GK12/lessons.htm Lincoln County Schools. (2012). Formative Assessment Strategies. Retrieved April 23, 2012, from http://www.lincoln.k12.or.us/Files/Formative Assessment Strategies.pdf