CHAPTER 10 MENDEL AND MEIOSIS WHAT YOU’LL LEARN: **THE BASIC CONCEPT OF GENETICS **THE PROCESS OF MEIOSIS WHY IT’S IMPORTANT: **YOU INHERITED TRAITS FROM YOUR PARENTS. **IF YOU KNOW MEIOSIS YOU WILL SEE HOW TRAITS ARE PASSED TO OFFSPRING. 10.1 MENDEL’S LAWS OF HEREDITY ▸I. Why Mendel Succeeded –**Mendel lived in a monastery in the mid 1800's –**Heredity - the passing of characteristics from parents to offspring –**Genetics - the study of heredity. A. Mendel chose his subject carefully ▪1. Mendel chose garden peas. ▪2. Gametes - distinct male and female sex cells ▪3. Pollination - transfer of pollen to pistil ▪4. Fertilization - uniting of male and female ▪ gametes ▪B. Mendel was a careful researcher ▪ ▪ He studied one trait at a time to control variables II. Mendel’s Monohybrid Crosses ** Hybrid - the offspring of parents that have different forms of a trait **Monohybrid - One trait ▪ A. The first generation ▪P + => ▪ B. The second generation ▪ F1 The Rule of United Factors ▸1. Each organism has two factors to control each trait. ▸2. These factors we call genes they are located on the chromosomes. ▸3. Alleles - different forms of the same gene. The Rules of Dominance ▸1. Dominant - Trait expressed without exception ▸2. Recessive - Trait that may be hidden by the dominant trait. ▸3. Symbols: Capital for Dominant Lower case for recessive. ▪ E. The law of Segregation ▪ III. Phenotypes and Genotypes ▸1. Phenotype - The way an organism looks and behaves. ▸2. Genotype - The gene combination an organism contains. ▸3. Homozygous - The two alleles for the trait are the same. ( TT or tt ) ▸4. Heterozygous - The two alleles for the trait are different. ( Tt ) ▪ IV. Mendel’s Dihybrid Crosses ▸ Organisms that differ from each other by two traits ▪ V. Punnett Squares ▸ A shorthand way of finding the expected proportions of a cross. ▪ VI. Probability ▸The likelihood that a trait will be shown ▪ 10.2 Meiosis ▸A. Diploid and haploid cells. – 1. Chromosomes are in pairs - one from the mom and one from the dad. – 2. Diploid - A cell with two of each kind of chromosome ( 2N ) – 3. Haploid - one of each kind of chromosome, these are gametes (N) ▪ B. Homologous Chromosomes ▸ Pair of chromosomes that have genes for the same traits. May not be identical alleles. ▪ C. Why Meiosis ▸ 1. Produces gametes containing half the number of chromosomes as a parent body cell has. ▸ 2. Male gametes are called sperm. ▸ 3. Female gametes are called eggs. ▸ 4. A zygote results when an Egg and a Sperm unite. This is sexual Reproduction ▪ III The phases of Meiosis ▸A. Interphase – 1. Cell replicates its chromosomes => – 2. Has two identical sister chromatids ▪ B. Prophase I ▸1. Each pair of homologous chromosomes comes together ▸2. Crossing over - chromosomes can exchange genetic material ▸3. In humans the average is two to three crossovers per pair. ▪ C. Metaphase I ▸The Homologous pairs of chromosomes line up along the equator ▪ D. Anaphase I ▸ The homologous pairs of chromosomes separate. ▪ E. Telophase I ▸Cytoplasm divides to yield two new cells with half the number of chromosomes Meiosis Provides for Genetic Variations ▸ A. genetic recombination - The reassortment of genetic information resulting from crossing over and independent segregation. ▸ B. Meiosis Explains Mendel’s results ▪ IV. Mistakes in Meiosis ▸Nondisjunction - failure of homologous chromosomes to separate properly. ▸A. Trisomy - one extra chromosome (Downs Syndrome) XXX ▸B. Monosomy - one less chromosome. In humans most zygotes with Monosomy do not survive. (Turners Syndrome) XO ▸C. Triploidy - Inherits an additional whole set of chromosomes. ▸D. Polyploidy - more than the usual sets of chromosomes – rare in animals, many in plants