The Excretory System 1 Vena2cava 3 The Urinary System And Excretion 1. Renal vein 4 2. Vena cava 7 3. Kidney 4. Ureter 5. Urinary bladder 6. Urethra 5 6 7. Aorta Waste Products of Metabolism 1. Amino acids 2. Ammonia 3. Uric acid Protein Amino1 Acids 4. Urea Ammonia 2 Ammonia (Fish) Uric3Acid (Insects, Reptiles, Birds) 4 Urea (Mammals) 1 1. 2 Pyramid – the pyramid is a group of collecting ducts 2. Renal artery – this artery branches off the aorta 3. Renal vein – this vein dumps its blood into the vena cava 4. Renal pelvis – Urine collects in this hollow area of the kidney 5. Ureter – this tube transports urine to the urinary bladder 3 4 5 1. Bowman’s (Nephron) capsule 3. Peritubular capillary 2. Proximal tubule 5. Collecting duct 4. Loop of Henle (Nephron Loop) 6. Renal cortex – the outer part of the kidney 7. Renal medulla – the middle part of the kidney 6 7 1 2 3 4 5 3 6 Peritubular Capillary Distil Tubule 4 Proximal Tubule 2 ------- 1 ---- ---- Renal Artery Cortex ------------------Medulla Collecting Duct Bowman’s(Nephron) Capsule 7 8 Loop of Henle (Nephron Loop) 5 Gradient of Increasing Sodium Concentration Glomerulus ---- ---- Cortex ------------------Medulla Gradient of Increasing Sodium Concentration ------- The Three Process In Urine Formation 1. Glomerular filtration • Small substances are forced by blood pressure through the glomerulus into the nephron capsule 2. Tubular Reabsorption Glomerulus • Water, salt, and glucose are reabsorbed into the blood stream. Most of the reabsorption takes place in the proximal tubule 3. Tubular Secretion • Substances are secreted from the bloodstream into the distil tubule The Three Steps of Urine Formation • What is the site of glomerular filtration? Substances are filtered from the blood through the walls of the glomerulus into the nephron capsule • What is the primary site of reabsorption? The proximal tubule is where most water, all glucose, and most salts are reabsorbed from the nephron back into the blood stream • What is the primary site of secretion? Drugs (legal and illegal), hydrogen ions, antibiotic, are secreted from the blood stream into the distil tubule. These substances end up in the urine. This is why testing the urine for recently used drugs works