Learning Journey GCSE Target Grade Year 9 B1 You and your Genes Name Key words Aim: ‘What will I be learning?’ You will be learning what key words such as gene, DNA, chromosome, inherited and variation mean. You will be learning that characteristics can be caused by genes, the environment or both. You will be learning what a clone is and how to clone plants and animals. You will be learning how gender (sex) is determined in humans during fertilization. You will be learning how a fetus can be tested for genetic disorders. You will be learning that embryo screening may cause ethical dilemmas. Gene Fetus Chromosome Clone Genetic testing Cystic fibrosis Huntington’s disorder Asexual Allele Dominant Recessive Homozygous Heterozygous Amniocentesis Genotype Phenotype Objectives: ‘How will I be learning?’ You will be learning by cloning your own cauliflower plants. You will be learning by thinking and discussing ethics relating to genetic testing of fetuses. You will be learning by researching the HFEA. You will be learning by drawing punnet squares and calculating probabilities. You will be learning by performing role plays about ethical issues. You will be learning by modeling fertilization. Literacy Describe how to carry out genetic testing. Numeracy Calculate and analyse risks of genetic testing. Discuss ethical arguments. Calculate probability of inheriting genetic disorders. Date Current Level Teacher comment December 2012 Date Interim Grade Date Final Grade Pupil comment Lesson The same and different 1 *Bold = higher tier only Notes The same but different 2 Cloning 1 3 What makes you the way you are? 4 Male or female 5 Inherited disorders A unique mix of genes Predicting inheritance Genetic testing of fetuses 9 Using genetic testing 10 Can you choose your child? 11 Cloning 2 12 13 Explain how embryos can be selected by genetic testing before implantation (PGD). Know that PGD stands for PreImplantation Genetic Diagnosis. Give examples of organisms that reproduce asexually to produce clones. Know that cloning depends stem cells. Explain that differences between clones can only be due to the environment. Describe how natural and artificial clones are produced. Explain how stem cells can be used to treat some illnesses. 6 7 8 Know what key words e.g. nucleus, gene, chromosome, DNA mean. Give examples of characteristics caused by genes or by the environment. Clone some cauliflower (practical) Understand that body cells have 46 chromosomes, in 23 pairs. Remember that males have XY and females have XX chromosomes. Know that genetic disorders can be caused by dominant or recessive alleles. Understand that an allele is a different version of a gene. Know the symptoms of Cystic Fibrosis (CF). Describe the uses of genetic testing for screening of fetuses. Describe the uses of genetic testing for predictive testing for genetic diseases. Explain where genes are found and what their function is. Give examples of characteristics caused by both genes and the environment. Understand how to keep conditions sterile. Understand that sex cells have 23 single chromosomes. Play a game to show how gender is inherited. Understand what homozygous and heterozygous alleles means. Know that Cystic Fibrosis (CF) is caused by a recessive faulty allele. Discuss the risks and implications of genetic testing of fetuses. Discuss ethical issues relating to testing fetuses using ethical arguments. Know that proteins can be structural or functional. Give examples of characteristics caused by several genes working together. Describe how clones are formed by asexual reproduction Explain how chromosomes pair up at fertilization. Draw a punnet square to show inheritance of gender. Know that Huntington’s disorder is caused by a dominant faulty allele. Draw a punnet square to show inheritance of Huntington’s disorder . State which characteristics an organism will show for a given pair of alleles. Draw a punnet square to show inheritance of Cystic Fibrosis (CF). Recognise questions with values that cannot be answered by Science. Explain the implications of testing children and adults for alleles which cause genetic diseases. Describe the implications of embryo selection. Understand how this ‘pairing up’ causes variation in offspring. Explain the link between the SRY gene and the development of sex organs in the fetus. Explain the terms genotype and phenotype. Understand what a carrier is and how they pass on a disease to their offspring. Discuss ethical issues using ethical arguments. Explain the implications of genetic testing by others eg. employers and insurance companies. Describe the role of the regulatory body (HFEA) in the decision making process. Understand that cloning uses stem cells. Stem cells Explain the difference between Embryonic Stem Cells (ESC) and Adult Stem Cells (ASC). Discuss the ethical issues relating to cloning of human cells.