GCSE Target Grade Year 9 B1 You and your Genes Name Aim: ‘What will I be learning?’ Ideas about Science (IaS) What key words such as gene, DNA, chromosome, inherited and variation mean That characteristics can be caused by genes, the environment or both. What a clone is and how to clone plants and animals. How gender (sex) is determined in humans during fertilization. How a fetus can be tested for genetic disorders. That embryo screening may cause ethical dilemmas. Objectives: ‘How will I be learning?’ (IaS 6) By cloning your own cauliflower plants. By thinking and discussing ethics relating to genetic testing of fetuses. By researching the HFEA. By drawing punnet squares and calculating probabilities. By performing role plays about ethical issues. By modeling fertilisation. Date Current Level Teacher comment December 2013 Date Media Watch Grade Key words Making decisions about science and technology (6) 6.3 –Discuss the official regulation of scientific research e.g. by the HFEA 6.4 –Decide which questions can/cannot be answered using a scientific approach because they involve values (ethics) 6.5 – Some forms of scientific research and applications of scientific knowledge, have ethical implications. Summarise why people may agree/disagree about what should be done (or permitted). 6.6 – Discuss arguments that either the right decision is one which leads to the best outcome for the greatest number of people involved, or that certain actions are considered right or wrong whatever the consequences Date B1 unit test Grade Gene Cystic fibrosis Allele Recessive Amniocentesis Clone Chromosome Huntington’s disorder Fetus Homozygous Genotype Ethical Genetic testing Asexual Dominant Heterozygous Phenotype Decision Literacy Describe how to carry out genetic testing. Numeracy Calculate and analyse risks of genetic testing. Discuss ethical arguments. Calculate probability of inheriting genetic disorders. Pupil comment The same and different 1 Know what key words e.g. nucleus, gene, chromosome, DNA mean. The same but different 2 Give examples of characteristics caused by genes or by the environment. Explain where genes are found and what their function is. Give examples of characteristics caused by both genes and the environment. Know that proteins can be structural or functional. Give examples of characteristics caused by several genes working together. Cloning 3 Clone some cauliflower (practical) and understand how to keep conditions sterile. Describe how clones are formed by asexual reproduction and give examples of organisms that produce clones. Explain that differences between clones can only be due to the environment. Describe how natural and artificial clones are produced. What makes you the way you are? 4 Understand that body cells have 46 chromosomes, in 23 pairs. Male or female 5 Remember that males have XY and females have XX chromosomes. A unique mix of genes 6 Understand that an allele is a different version of a gene. Understand that sex cells have 23 single chromosomes. Play a game to show how gender is inherited. Understand what homozygous and heterozygous alleles means. Explain how chromosomes pair up at fertilization. Draw a punnet square to show inheritance of gender. State which characteristics an organism will show for a given pair of alleles. Understand how this ‘pairing up’ causes variation in offspring. Explain the link between the SRY gene and the development of sex organs in the fetus. Explain the terms genotype and phenotype. Predicting inheritance 8 Know the symptoms of Huntington’s disorder and Cystic Fibrosis (CF). Know that Huntington’s disorder is caused by a dominant faulty allele and that CF is caused by a recessive faulty allele. Draw a punnet square to show inheritance of Huntington’s disorder and CF. Genetic testing of fetuses 9 Describe the uses of genetic testing for screening of fetuses. 10 Describe the uses of genetic testing for predictive testing for genetic diseases. Discuss the risks and implications of genetic testing of fetuses. Discuss ethical issues relating to testing fetuses using ethical arguments. Know that PGD stands for PreImplantation Genetic Diagnosis. Explain how stem cells can be used to treat some illnesses. Explain the implications of testing children and adults for alleles which cause genetic diseases. Explain the implications of genetic testing by others eg. employers and insurance companies. Describe the implications of embryo selection. Explain the difference between Embryonic Stem Cells (ESC) and Adult Stem Cells (ASC). Discuss the ethical issues relating to cloning of human cells. Recognise questions with values that cannot be answered by Science. Understand what a Discuss ethical carrier is and how they issues using pass on a disease to ethical their offspring . arguments. Using genetic testing Can you choose your Stem cells child? 11 13 Explain how embryos Know that cloning can be selected by depends on stem genetic testing cells. before implantation (PGD). Describe the role of the regulatory body (HFEA) in the decision making process.