Week 1 notes Protein structure Water Vitamins Minerals 11 Warmup Warmup 6/2 • How do the following factors affect enzyme activity? – Temperature (temperatura) – Substrate concentration (cantidad de sustrato) – Enzyme concentration (cantidad de enzima) – Competitive inhibition (sustancias inhibidoras) Protein structure: • ________________ – Linear sequence of a chain of amino acids • (this sequence is derived from the cell’s DNA code) • Secondary – Shows the ____________________ of the chain due to hydrogen bond interactions between amino acids in different locations in the chain – (1 of 2 basic shapes form: alpha helix, pleated sheet) • _____________ – The folding of an alpha helix or beta sheet back onto itself due to various intermolecular forces • Adds stability • Quaternary – Complex structure formed by ___________________ polypeptide chains combining Protein structure What do you know about Water? • How does it contribute to cell structure? • What is its role in cell transport? • How does it regulate temperature? • It is the universal ______. – Which means… – Important because…. Minerals and Ions (iones y sales minerales) • What are they? Examples? – ____________________ that you consume in the form of various salts dissolved in food and water • Difference between _______________… – Cat= + (Na+, K+, Mg2+) – An = - (Cl-, HCO3-, PO43-) • How do they contribute to the structure of living things? – Salts precipitate out and form solid/insoluble structures that often have skeletal function • How do they function as cofactors/coenzymes for catalysts(enzymes)? – Enzymes cannot work without co-factors, and each enzyme is designed to work with a particular co-factor. You have heard of these co-factors, they are called "minerals” (and vitamins). Unless an enzyme is accompanied by its cofactor/mineral, or a substitute co-factor/mineral, it will simply sit around doing nothing. ______________________________________________ • How do they regulate pH? • _____________with either excess H+ or excess OH- _______________________ You need to be familiar with… • • • • • • • • • • Calcium (Calcio) Potassium (Potasio) Sodium (Sodio) Phosphorus (Fósforo) Magnesium (Magnesio) Iron (Hierro) Zinc (Zinc) Chlorine (Cloro) Sulfur (Azufre) Copper (Cobre) • …Make flashcards… • Study them • Quiz tomorrow Vitamins… • You take a vitamin tablet in the morning. Someone says eat your fruit and vegetables because they have vitamins. • What’s so important about vitamins? • Functions THEY DO • they do help to convert energy into the energy form your body uses • They do improve and assist enzymatic reactions THEY DON’T • While they do not provide energy like protein from meat and sugar from breads, • They are not components of tissue structure like macromolecules. Classification Water soluble (hidrosoluble) Fat soluble (liposoluble) • _____________________ • _________________ • travel freely through the body, and excess amounts usually are _________by the kidneys (_____________) • Found in fat-containing foods • _________in the body's cells and are not excreted as easily as water-soluble vitamins • Body needs frequent, small doses • Do not need to be replenished as often because they are stored • Not as likely to be toxic (they’re excreted too quickly) • Too much could be toxic (especially A and D) Homework • Memorize vitamins and minerals • Quiz over water, vitamins, minerals, enzymes and protein structure TOMORROW