Chapter 2: Biology and Behavior Lecture 3 Learning Outcomes • Describe the nervous system, including neurons, neural impulses, and neurotransmitters. • List the structures of the brain and their functions. Learning Outcomes • Describe evolutionary psychology and the connections between heredity, behavior, and mental processes. The Nervous System: On Being Wired 1. Neurons • Neurons, responsible for all our sensations, behaviors and mental processes, our nervous system composed of those cells – Cell body-soma, dendrites, axon and axon terminals • Glial cells (# increases when we grow up) – Nourish and insulate neurons – Direct growth of neurons – Remove waste products • Myelin sheath (axon is wrapped w/it, white, fatty) 2. The Anatomy of a Neuron 3. Neurons • Afferent Neurons/Sensory – Transmit messages from sensory receptors to the spinal cord and brain • Efferent Neurons/Motor – Transmit messages from bran or spinal cord to muscles and glands SAME 4. Neural Impulse • Electrochemical messages that travel within neurons • Resting potential (-70), because of Sodium (Na+) Potassium(K+) pumps and chloride (Cl-) – Neuron is not responding to other neurons • Electrotonic potential (will sum up in soma) • Action potential – Conduction of neural impulse along axon 4. Neural Impulse • Electrochemical messages that travel within neurons • Resting potential (-70), because of Sodium (Na+) Potassium(K+) pumps and chloride (Cl-) – Neuron is not responding to other neurons • Action potential – Conduction of neural impulse along axon (e.g.,-55ml- Na+ channels open up, and Na+ floods in until +30 or +40, then Na+ channel closes and Potassium K+ channels open up until -80 ) Action Potential PLAY VIDEO 5. Firing: Neuron to Neuron • Firing – Conduction of neural impulse along the length of a neuron • Threshold – Incoming messages reach a strength at which neuron will fire (e.g.,-55ml- Na+ channels open up, and Na+ floods in until +40, then Na+ channel closes and Potassium K+ channels open up until -80 ) 6. Firing: Neuron to Neuron • All-or-none principle – Every time a neuron fires, it transmits an impulse of the same strength. • Refractory period – Period of recovery time between firings 7. Firing: Neuron to Neuron • Synapse – Fluid-filled gap (Synaptic cleft) between • Axon terminal from transmitting neuron, and • Dendrite of receiving neuron Synaptic Transmission PLAY VIDEO 8. Neurotransmitters • Neurotransmitters – Chemical substances that communicate from one neuron to another • Synaptic vesicles – Contain neurotransmitters in the axon terminals 9. Neurotransmitters • Receptor site – On dendrite of receiving neuron • Reuptake – Neurotransmitters reabsorbed 10.Neurotransmitters • Excitatory neurotransmitter (e.g., Na+ channels open) – Cause other neurons to fire • Inhibitory neurotransmitters (e.g., Potassium K+ channels open) – Prevent other neurons from firing To Sum up: Firing • Neurons communicate by firing. Steps: a). Neurotransmitters are released into synapse by a pre-synaptic neuron b). Neurotransmitters bind with receptors on the post-synaptic neuron’s dendrites c). Excitatory and inhibitory messages are compared in the cell body (soma) of the postsynaptic neuron. d). If the receptors allow a sufficient excess of excitatory neurotransmitters into the cell, the postsynaptic neuron will respond by opening its sodium and potassium gates. e). The charge inside the cell goes from negative to positive f). The gates open in succession as the information is passed along the axon away from the cell body and toward terminal buttons. g). The sodium and potassium gates close, and the neuron returns to its resting potential h). The synaptic neuron “reuptakes” the neurotransmitter from the synapse. 11. Neurotransmitters of Interest to Psychologists • Acetylcholine (ACh) – Controls muscle contractions (excitatory between nerves muscles & inhibitory at the heart and some other locations) • Paralysis if not enough ACh – Memory (prevalent in hippocampus, when decrease ) • Alzheimer’s disease • Acetylcholine (ACh), Dopamine, norepinephrine, serotonin, GABA, and endorphins 12. Neurotransmitters of Interest to Psychologists • Dopamine – Pleasure, voluntary movement, learning, memory – Parkinson’s disease (deficiencies in D.) – Schizophrenia (people have more receptors for dopamine, utilize more dopamine) -Phenothiazines block dopamine receptors • Acetylcholine (ACh), Dopamine, norepinephrine, serotonin, GABA, and endorphins 13. Neurotransmitters of Interest to Psychologists • Norepinephrine in the brain stem – Excitatory neurotransmitter, also hormone • Accelerates heart rate, affects eating, linked to activity levels, learning and remembering – Mood disorders, depression, bipolar disorder (more) -- Deficiency impairs memory -- Cocaine and amphetamines boost N. • Acetylcholine (ACh), dopamine, norepinephrine, serotonin, GABA, and endorphins 14. Neurotransmitters of Interest to Psychologists • Serotonin – Emotional arousal and sleep – Eating disorders, alcoholism, depression, aggression, insomnia – LSDs decrease action of S. Acetylcholine (ACh), dopamine, norepinephrine, serotonin, GABA, and endorphins 15. Neurotransmitters of Interest to Psychologists • Gamma-aminobutyric acid (GABA) – Inhibitory may help relax anxiety reactions – Depression 16. Neurotransmitters of Interest to Psychologists • Endorphins similar to morphine – Occur naturally within the brain and bloodstream – Inhibit pain – Increase sense of competence, immune – May be connected to indifference to pain • Runner’s high 17. Parts of the Nervous System • Central Nervous System – Brain and spinal cord • Peripheral Nervous System – Sensory (afferent) and motor (efferent) neurons The Divisions of the Nervous System 18. Peripheral Nervous System • • Somatic Nervous System – Sensory and motor neurons – Transmits messages to the brain and purposeful body movements from the brain Autonomic Nervous System – Regulates glands and muscles of internal organs – Contains sympathetic and parasympathetic divisions 19. Branches of Autonomic Nervous System • Sympathetic – Most active during emotional responses – Spend the body’s reserves of energy • Parasympathetic – Most active during processes that restore body’s reserve of energy 20. Central Nervous System • Spinal Cord –”information superhighway” – Transmits messages from sensory receptors to the brain and from the brain to muscle and glands • Spinal Reflex- “local government” – Simple, unlearned response to stimulus • Gray matter, involved in spinal reflexes • White matter The Reflex Arc The Brain: Wider Than the Sky Lecture 4. How Do Researchers Learn About the Functions of the Brain • Experimenting with the brain – Assessing damage from trauma and disease – Intentionally damaging parts of a brain – Electrical probes to stimulate parts of the brain • Electroencephalograph (ECG) – Measurement of electrical activity – brain waves How Do Researchers Learn About the Functions of the Brain (continued) • Brain-Imaging Techniques – Computerized axial tomography (CAT or CT scan) – Positron emission tomography (PET scan) – Magnetic Resonance Imaging (MRI) – Functional Magnetic Resonance Imaging (fMRI) 1.Structures and Functions of the Brain • Hindbrain – Medulla -heart rate, blood pressure, respiration/breathing sleeping, sneezing, coughing. – Pons- body movements related to attention, sleep, alertness, respiration – Cerebellum- balance, controls motor behavior-e.g., playing guitar , walking to refrigerator. 2. Structures and Functions of the Brain • Reticular Activation System – Vital to attention, sleep, arousal – Injury to the RAS results in coma – -alcohol lowers RAS activity 3. Structures and Functions of the Brain • Forebrain includes the thalamus, hypothalamus, limbic system, & cerebrum – Thalamus • Relay station for sensory stimulation – Hypothalamus • Regulates body temperature, motivation and emotion • Hunger, thirst, sexual behavior, caring for offspring, aggression 4. Structures and Functions of the Brain • Forebrain – Limbic System, includes the amygdala, hippocampus, & parts of hypothalamus – Involved in memory, emotion, hunger, sex drive, & aggression • Amygdala- fear Involved in memory and emotion 5. Structures and Functions of the Brain • Cerebrum – Responsible for thinking and language – Cerebral Cortex • Surface of cerebrum – Corpus Callosum • Connects two hemispheres 6. The Brain: Corpus Callosum PLAY VIDEO 7. The Cerebral Cortex • Outer layer of cerebrum • Two Hemispheres • Four Lobes – Frontal, Parietal, Temporal and Occipital 8. The Lobes of the Cerebral Cortex • Occipital Lobe – Vision • Temporal Lobe – Hearing and Auditory functions • Parietal Lobe – Somatosensory Cortex, m. from skin • Frontal Lobe – Motor Cortex The cerebral cortex. Which of the following body parts is associated with the greatest amount of brain tissue in the motor cortex? 9. Thinking, Language, and the Cortex • Association areas – Not primarily involved in sensation or motor activity – Responsible for learning, thought, memory and language • Association areas in frontal lobe – Responsible for executive functions 10.Language Functions • Two hemispheres of the brain mirror and differ – Left hemisphere contains language functions for nearly all people – If damaged before age 13, speech functions would transfer to right hemisphere • Two key language areas – Broca’s area & Wernicke’s area – Damage in either causes aphasia 11. Language Functions • Wernicke’s Area – Temporal Lobe – Wernicke’s aphasia • Impairs ability to comprehend speech and think of words to express own thoughts • Angular Gyrus – Translates visual into auditory information – Damage impairs reading ability 12. Language Functions • Broca’s Area – Frontal Lobe – Production of speech – Broca’s aphasia • Understand language but speak slowly and laboriously 13. Left Brain, Right Brain • Left-brained – Logical and intellectual • Right-brained (visual-spacial) – Intuitive, creative and emotional • Hemispheres do not act independently – Exaggerated idea 14. Handedness • Left-handed – Somewhat greater-than-average probability of language problems and certain health problems – More likely than right-handed people in gifted artists, musicians, and mathematicians • Origins of handedness – Genetics – 1 left-handed parent -80% to be right handed; 2 left-handed parents-50% 15. Split-Brain Experiments • Severe cases of epilepsy may require split-brain operations • Examples of “two brain” phenomenon – Caused by inability of one hemisphere to communicate with the other Evolution and Heredity: The Nature of Nature Darwin’s Theory of Evolution • Struggle for existence • Natural selection – Species and individuals compete for same resources • Mutations – Random genetic variations explain differences – Differences which affect the ability to adapt to change Evolutionary Psychology • Ways in which adaptation and natural selection are connected with behavior and mental processes • Behavior patterns evolve and can be transmitted genetically from generation to generation – Instinctive or species specific behaviors Evolutionary Psychology • Instinct – Stereotyped patterns of behavior that are triggered in a specific situation • Species-specific – Resists modification, not learned Heredity, Genetics and Behavioral Genetics • Heredity – Transmission of traits from parent to offspring, based on genes • Genetics – Subfield of biology that studies heredity • Behavioral Genetics – Focuses on individual differences Genes and Chromosomes • Gene – Basic unit of heredity • Chromosomes – Structure within cell nucleus that carry genes – Humans have 46 chromosomes (23 pairs) • DNA (deoxyribonucleic acid) – Substance that forms chromosomes – Double helix – contains genetic code – Nucleotides - A and T, C and G Cells, Chromosomes, and DNA Genes and Chromosomes • Genes regulate development of specific traits – Some traits are determined by one gene – Other traits are polygenic Genes and Chromosomes • Genotype – Individual’s genetic makeup (nature) • Phenotype – Actual appearance, based on genotype and environmental influences (nurture) Chromosomes • Receive 23 chromosomes from father’s sperm and 23 chromosomes from mother’s egg cell • 23rd pair of chromosomes are sex chromosomes – XX – female – XY – male • Down syndrome – Chromosomal abnormality Kinship Studies • Focus on presence of traits and behavior patterns in people who are, or are not related biologically • Twin studies – Monozygotic twins – Dizygotic twins • Adoption studies Left Handedness • 8 to 10% of people are left handed – More common in boys than girls – More common in gifted artists than general population • Language and Health Problems – Dyslexia, stuttering – Migraine headaches, allergies • Appears to have a genetic component Selective Breeding • Process used to enhance desired physical and behavioral traits – Done routinely with plants and animals