Multiple Alleles - Sarah Pasela's Weebly

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M

ULTIPLE

Blood Types

A

LLELES

A, B, O B

LOOD

T

YPE

S

YSTEM

Multiple alleles

more than two alleles control a trait

A, B, O System

Alleles are either A, B, or O

Blood types can be A,

B, AB, or O

Example – Human

Blood Types

Blood type is determined by the type of antigen present on the surface of the red blood cell

A

NTIGENS AND

A

NTIBODIES

Antigens – stimulates an immune response when a foreign substance enters the body

Antigens produce antibodies

Antibodies are like

“soldiers,” they destroy foreign substances

B

LOOD

T

YPES

D

ONORS AND

R

ECIPIENTS

Which blood type(s) can A, B, AB, and O receive?

Which blood type(s) can A, B, AB, and O donate to?

Blood Type

A

B

*AB

Universal recipient

*O

Universal donor

Can get blood from…

O, A

O, B

A, B, AB, O

O

Can donate to…

A, AB

B, AB

AB

A, B, AB, O

M

OST

/L

EAST

C

OMMON

B

LOOD TYPE

Most Common Blood type

O

A

B

AB

Least Common Blood type

R

H

S

YSTEM

Rh is an antigen that is sometimes present on the surface of red blood cells

85% of the United States population is Rh positive

(Rh+).

This means that they carry the Rh antigen

People who do not have the Rh antigen are called Rh

negative (Rh-)

Called the Rh factor

Named after the rhesus monkey in which it was first discovered

Rh+ is dominant over Rh-

People who are Rh- CANNOT receive blood from a person who is Rh+!

If an Rh- person receives a transfusion that is Rh+

 the Rh- person will make antibodies against the Rh+ blood

The antibodies will react with the antigens of the Rh+ blood and the two blood types will clump

This clumping is called AGGLUTINATION

R

H AND

P

REGNANCY

If mom is Rh- and dad is

Rh+ = baby will be Rh+

During delivery baby’s blood may get into mom’s bloodstream and she will make antibodies against the Rh+ blood

If she gets pregnant again her antibodies against Rh+ blood can cross her placenta and attack baby

#2 Rh+ blood

P

RACTICE

-

COPY IN YOUR NOTES

=)

If one parent has type O blood and the other parent has type AB, what are the possible blood types the offspring could have?

O O

A O A O

A

B O B O

B

If both parents are rH+ , is it possible to have a child that is rH- ???

If both parents are type AB, what are the possible blood types of the offspring?

If one parent is type A and the other parent is type AB, what is the chance of having a child with AB?

If one parent is type A and the other parent is type B is it possible for them to have an AB child?

If one parent is A and the other parent is B, is it possible for them to have a child with type O?

If one parent is type A and rH+ and the other parent is B and rH+ is it possible to have a child that is type AB and rh- ? Hint, do your Punnett squares separately!

If one parent is type AB and rH+ and the other parent is AB and rH+, what is the chance of having a child that is type B and rH-?

Hint, both parents are heterozygous for rH factor.

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