University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet Date_________________ Client’s Initials ________ Student ____________________________ Allergies: Priority Nursing Diagnosis: Long and Short term goals (must be measurable): Interventions: MEDICATION WITH INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED PRESCRIBED DOSEAGE EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. CLASSIFICATION OF THE THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, DRUG LAB RESULTS AND USUAL DOSE/SAFE DOSE PROCEDURES AND ADMINISTRATION Reglan (metoclopramide Prevents or minimizes nausea Adverse Effects: Effects on lab test results: hydrocholoride) and vomiting. Also reduces gag CNS: anxiety, dizziness, *May increase aldosterone and reflex, improves gastric drowsiness, dystonic reactions, prolactin levels Pharmacologic Class: para emptying, and reduces gastric extrapyramidal symptoms, *May decrease neutrophil and aminobenzoic acid derivative, reflux fatigue, fever, headache, granulocyte counts dopamine receptor agonist insomnia, lassitude, restlessness, sedation, seizures, Considerations: Therapeutic Class: antiemetic, suicidal ideation, tardive *Contraindicated in pts GI stimulant dyskinesia hypersensitive to drug CV: arrhythmias, AV block, *Use cautiously in patients To prevent or reduce bradycardia, heart failure, with hx of depression, postoperative nausea and hypotension, transient Parkinson disease, HTN, or vomiting: 10-20 mg I.M. near hypertension renal impairment end of surgical procedure, GI: bowel disturbances, *Safety and effectiveness repeat q4-6h PRN diarrhea, nausea haven’t been established for Hematologic: agranulocytosis, therapy that lasts longer than 12 Dilute doses larger than 10 mg leucopenia, neonatal weeks in 50 ml of compatible dilutant, methemoglobinemia, *In pregnant women use and infuse over at least 15 neutropenia cautiously minutes Skin: rash *In breast feeding women use Other: loss libido, prolactin cautiously it is unknown if the Give doses of 10 mg or less by secretion drug appears in breast milk direct injection over 1-2 *Use cautiously in elderly pts minutes 1/2009 N478 Drug Sheet University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet Drugs Interactions: Patient Education: Drug-Drug: acetaminophen, *Instruct patient not to drink aspirin, diazepam, levodopa, alcohol during therapy lithium, anticholinergics, *Advise patient to avoid opiods, CNS depressants, activities requiring alertness for Digoxin, insulin 2 hours after taking each dose Drug-Lifestyle: alcohol use 1/2009 N478 Drug Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Zantac (rantitidine hydrochloride) Antiulcerative, H2 receptor antagonist Administration: 150 mg PO bid or 300 mg hs, or 50 mg IV or IM q6-8h To give drug by intermittent IV infusion dilute 50 mg (2ml) in 100 ml compatible solution and infuse at a rate of 5-7 ml/min (premixed solution does not need to be diluted) 1/2009 N478 Drug Sheet University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Relieves GI discomfort Adverse Reactions: CNS: malaise, vertigo EENT: blurred vision GI: abdominal discomfort, constipation, diarrhea, nausea, vomiting Hematologic: pancytopenia, reversible leucopenia, thrombocytopenia Hepatic: jaundice Skin: rash Other: anaphylaxis, angioedema, burning and itching at injection site Drug Interactions: Drug-Drug: antacids, diazepam, glipizide, procainamide, warfarin Drug-Lifestyle: smoking Effects on Lab Test Results: may increase creatinine and ALT levels May decrease RBC, WBC, and platelet counts May cause false positive test for urine protein using multistix Considerations: contraindicated in patients hypersensitive to the drug or any of its components Use cautiously in patients with hepatic dysfunction. Adjust dosage in patients with impaired kidney function In children safety and effectiveness haven’t been established for pathological hypersecretory conditions or the maintenance of healing duodenal ulcer. In neonates younger than one month, safety and effectiveness haven’t been established In elderly patients use cautiously University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet Page _____ of ______ Patient Teaching: remind patient taking drug once daily to take it at bedtime Instruct patient to take drug with or without food Urge patient not to smoke cigarettes; smoking may increase gastric acid secretion and worsen disease 1/2009 N478 Drug Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Ancef (cefazolin sodium) Antibiotic, first generation cephalosporin Administration: 250 mg IV or IM q8h to 1g q6h…max 12g daily in life threatening situations Give 1g IV or IM 30-60 min before surgery; then 0.5 to 1g IV or IM q6-8h for 24 hours Reconstitute with sterile or bacteriostatic water as follows: 2ml to 500mg vial to yield 225 mg/ml; or 2.5 ml to 1g vial to yield 330 mg/ml…shake well If IV therapy >3d alternate sites University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Hinders or kills susceptible bacteria Adverse Effects: CNS: dizziness, headache, malaise, paresthesia GI: abdominal cramps, anal pruritus, anorexia, diarrhea, dyspepsia, glossitis, nausea, oral candidiasis, pseudomembranous colitis, vomiting, tenesmus GU: gential pruritus and candidiasis, vaginitis Hematologic: anemia, eosinophilia, leucopenia, thrombocytopenia, transient neutropenia Respiratory: dyspnea Skin: injection site reactions, maculopapular and erythematous rashes, Stevens Johsnon syndrome, urticaria Other: hypersensitivity reactions Drug Interaction: Drug-Drug: probenecid Effects on lab test results: *May increase ALT, AST, alkaline phosphatasae, bilirubin, GGT, and LDH levels *May increase eosinophil count. May decrease neutrophil, WBC, and platelet counts *May cause false positive urine glucose determinations with copper sulfate tests (Clinitest) Considerations: *Contraindicated in patients hypersensitive to other cephalosporins *Use cautiously in patients with a history of sensitivity to penicillin because of cross allergic reaction and in patients with renal impairment *In pregnant and breast feeding women use cautiously Patient Education: *Tell patient to report adverse reactions 1/2009 N478 Drug Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Vancocin (vacomycin) Pharmacologic Class: glycopeptides Therapeutic Class: antibiotic Administration: 500 mg IV over 1 hour, q6h, or 1 g q12h Dilute in 200 ml of saline solution injection or D5W… check site daily for phlebitis and irritation University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Kills susceptible bacteria Adverse Effects: CNS: fever, pain CV: hypotension EENT: ototoxicity, tinnitus GI: nausea, pseudomembranous colitis GU: nephrotoxicity Hematologic: eosinophilia, leukopenia Respiratory: dyspnea, wheezing Skin: red man syndrome Other: anaphylaxis, chills, superinfection, thrombophlebitis at injection site Drug Interactions: Drug-Drug: aminoglycosides, amphotericin B, cisplatin, pentamidine Effect on lab test results: *May increase BUN and creatinine levels *May increase eosinophil count. May decrease neutrophil and WBC counts Considerations: *Contraindicated in patients hypersensitive to the drug or any of its components *Use cautiously in patients receiving other neurotoxic, nephrotoxic, or ototoxic drugs; patients older than age 60; and those with impaired liver or kidney function, hearing loss, or allergies to other antibiotics *In pregnant women use cautiously *In breast feeding women safety and effectiveness haven’t been established Patient Education: *Tell patient to take entire amount of drug exactly as directed even after feeling better 1/2009 N478 Drug Sheet University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet Page _____ of ______ *Tell patient to stop taking the drug and immediately report any adverse reactions especially ringing in ears or fullness 1/2009 N478 Drug Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Versed (midazolam) Pharmacologic Class: benzodiazepine Therapeutic Class: sedative Administration: give 0.07 mg to 0.08 mg/kg IM about 1 hr before surgery…for induction of general anesthesia if the pt hasn’t received preanesthsia drug give 0.3 to 0.35mg/kg IV over 20-30 seconds; if they have then give 0.15-0.35mg/kg IV over 20-30 seconds When mixing infusion use 5mg/ml vial, dilute to 0.5 mg/ml with D5W or NS Give slowly over at least 2 minutes and wait at least 2 minutes when adjusting dose to desired effect 1/2009 N478 Drug Sheet University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Promotes calmness and sleep Adverse Effects: CNS: amnesia, combativeness, headache, involuntary movements, oversedation CV: cardiac arrest, hypotension, variations in blood pressure and pulse rate GI: hiccups, nausea, vomiting Respiratory: apnea, decreased respiratory rate Other: pain, tenderness at injection site Drug Interactions: Drug-Drug: cimetidine, verapamil, CNS depressants, diltiazem, flucoonazole, ketoconazole, miconazole, hormonal contraceptives, opiods, rifamycin Drug-Food: grapefruit juice Drug-Lifestyle: alcohol use Effect on lab test results: *None reported Considerations: *Contraindicated in patients hypersensitive to drug or any of its components *Use cautiously in patients with uncompensated acute illness and in debilitated patients *In pregnant women drug is contraindicated *In breast feeding women use cautiously its unknown if drug appears in breast milk *Use with caution in neonates and avoid rapid injection *Use cautiously in elderly Patient Education: *Use extra caution when teaching patient because drug will diminish predrug memory *Instruct patient not to use alcohol during therapy MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Diprivan (propofol) Sedative/hypnotic Administration: 40 mg every 10 seconds until induction of anesthesia (2-2.5 mg/kg) 100-200 mcg/kg/min (6-12 mg/kg/h) for maintenance of general anesthesia Most of time it is provided as a ready to use formulation…but if dilution is necessary it should only be diluted with 5% dextrose injection and should not be diluted to a concentration less than 2 mg/ml 1/2009 N478 Drug Sheet University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Initiates and maintains anesthesia Teach patient that performance of activities requiring mental alertness, such as operating a motor vehicle, or hazardous machinery or signing legal documents may be impaired for some time after general anesthesia or sedation *Patient remains sedated until drug effectively wears off *Patient reacts positively to drug therapy *Patient and family state understanding of drug therapy MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Anectine (succinylcholine) Pharmacologic Class: depolarizing neuromuscular blocker Therapeutic Class: skeletal muscle relaxant Administration: Dosage depends on anesthetic used, individual needs, and response…give 0.6mg/kg IV over 10-30 seconds; then give 2.5 mg/minute prn OR 2.5-4 mg/kg IM u p to max of 150 mg IM in deltoid muscle 1/2009 N478 Drug Sheet University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet INDIVIDUAL DESIRED NURSING IMPLICATIONS/ EVALUATION OF DESIRED EFFECT OF DRUG FOR CONSIDERATIONS FOR EFFECT FOR THE PATIENT. THIS PATIENT THIS PATIENT INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Relaxes skeletal muscle For lab results it may increase myoglobin and potassium levels Explain to patient all events and happenings because he can still hear, reassure patient that he is being monitored at all times, inform patient that postoperative stiffness is normal and will soon subside *Patient responds well to therapy *Patient maintains adequate respiratory patterns with mechanical assistance *Patient and family state understanding of drug therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Mivacron (mivacurium) Skeletal muscle relaxant Doses should be individualized and a peripheral nerve stimulator should be used to emasure neuromuscular function during administration in order to monitor drug effect and need for additional doses, confirm recovery from neuromuscular block Usually though doses are 0.15 mg/kg over 5-15 seconds, 0.20 mg/kg over 30 seconds, or 0.25 mg/kg in divided doses (IV) 1/2009 N478 Drug Sheet Page _____ of ______ EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Used as adjunct to general anesthesia…facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation Explain to patient all events and happenings, reassure patient that he will be monitored at all times, teach about post op stiffness (similar teaching to Anectine) *Patient reacts positively to drug therapy *Patient does not have an allergic hypersensitivity to the drug *Patient and family understand need for therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Zemuron (rocuronium) Skeletal muscle relaxant, neuromuscular blocking agent Recommended initial dose is 0.6 mg/kg…enough for sufficient intubation Maintenance dose is 0.1 to 0.2 mg/kg Best to keep dosages individualized though…the above are general dosages 1/2009 N478 Drug Sheet Page _____ of ______ EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Used ad adjunct to general anesthesia to facilitate both rapid sequence an routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation Teach patient about possible side effects such as having an anaphylactic reaction is possible and that hypotension is possible, request previous anaphylactic reactions to other neuromuscular blocking agents, reassure them that they will be monitored at all times and will not be left alone, teach patient that certain medical condition and medications may influence how it works *Patient reacts positively *Patient does not have an allergic reaction *Patient and family understand need for therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Atropine Antiarrhythmic, vagolytic, anticholinergic, belladonna alkaloid Administration: 0.4mg IM or subq 30-60 min before anesthesia (preop to decrease secretions), 0.5 to 1 mg IV push; repeat q3-5m to a max of 2 mg prn (for symptomatic bradycardia) Give by direct injection into a large vein or IV tubing over 1-2 minutes 1/2009 N478 Drug Sheet Page _____ of ______ EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Increases heart rate, decreases secretions, and slows GI motility. Antidote for anticholinesterase insecticide poisoning May increase WBC count *Patient underlying condition improves Teach patient about atropine sulfate theapy, instruct patient to ask for assistance with activities if adverse CNS reactions occur, teach patient how to handle distressing anticholinergic effects *Patient has no injury as a result of therapy *Patient and family state understanding of drug therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Robinul (glycopyrrolate) Class: anticholinergic Route: IV or IM Dosage: Preanesthetic Medication: The recommended dose of Robinul Injection is 0.004 mg/kg by intramuscular injection, given 30 to 60 minutes prior to the anticipated time of induction of anesthesia or at the time the preanesthetic narcotic and/or sedative are administered. Intraoperative Medication: Administered intravenously as single doses of 0.1 mg and repeated, as needed, at intervals of 2 to 3 minutes. 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES It is used as a preoperative antimuscarinic to reduce salivary, tracheobronchial, and pharyngeal secretions; to reduce the volume and free acidity of gastric secretions; and to block cardiac vagal inhibitory reflexes during induction of anesthesia and intubation. When indicated, Robinul Injection may be used intraoperatively to counteract surgically or drug- induced or vagal reflexes associated arrhythmias. Adverse Reactions: Xerostomia (dry mouth), urinary hesitancy and retention, blurred vision and photophobia due to mydriasis (dilation of the pupil), cycloplegia, increased ocular tension, tachycardia, palpitation, decreased sweating, loss of taste, headache, nervousness, drowsiness, weakness, dizziness, insomnia, nausea, vomiting, impotence, suppression of lactation, constipation, bloated feeling, severe allergic reactions hypersensitivity urticaria, pruritus, dry skin, some degree of mental confusion especially in elderly persons. Malignant hyperthermia, cardiac arrhythmias, cardiac arrest, hypertension, hypotension, seizures, and respiratory arrest Drug Interactions: anticholinergics and Effects on lab test results: Has not shown any effects. Consideration: Use caution in the elderly because they may be more sensitive to the effects of the drug, especially drowsiness, confusion, and urinary effects Patient Education: Caution not to engage in activities requiring mental alertness and/or visual acuity such as operating a motor vehicle or other machinery, or performing hazardous work while taking this drug. Use caution during exercise or hot weather since overheating may result in heat stroke. Sensitivity of the eyes to light. Avoid alcohol. University of Evansville Page _____ of ______ Department of Nursing and Health Sciences Drug Dispensing Sheet medications with anticholingeric activities may intensify the antimuscarinic effects and may result in an increase in anticholinergic side effects. 1/2009 N478 Drug Sheet University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Sublimaze (fentanyl) Class: Opiod Therapeutic Class: analgesic and anesthetic Route and Dosage: Injection 50 mcg/ml, Transdermal patch 12.5, 25, 50, 75, or 100 mcg/hr can be delivered, Transmucosal lozenge 200, 400, 600, 800, 1,200, 1,600 mcg, Transmucosal tablets 100, 200, 400, 600, 800 mcg. 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Used for postoperative pain, to manage persistent, moderate to severe chronic pain in opiodtolerant patients who require continous, around-the-clock opiod analgesics for an extended amount of time, breakthrough cancer pain in opiod-tolerant patients Adverse Reactions: anxiety, asthenia, clouded sensorium confusion, depression, dizziness, euphoria hallucinations, headache, nervousness, sedation, somnolence, arrhythmias, bradycardia, chest pain hypertension, hypotension, dry mouth, abdominal pain, constipation, nausea, vomiting, urine retention, apnea, dyspnea, hypoventilation, respiratory depression, diaphoresis, pruritis, physical dependence, reaction at site. Drug Interactions: CNS depressants, general anesthetics, hypnotics, MAOIs, opioid analgesics, sedatives, tricyclic antidepressants, diazepam, droperiod, CYP3A4 inhibitors, protease inhibitors, alcohol Effects on lab results: none reported. Consideration: Use cautiously in patients with renal impairment. Keep naloxone and resuscitation equipment available when giving IV. This drug is often used IV with droperidol to produce neroleptanalgesia. Monitor rate and depth of respirations along with oxygen saturation. Also monitor bladder function. Give drug before patient has intense pain. When given postop, have pt. turn cough and deep breathe to prevent atelectasis. Don’t use patch for post op pain. Immediately report respiratory rate less than 12/min. Patient Education: Consume lozenge in 15 minutes. Lozenge and tablets may be fatal to a child. Instruct how to properly place patch (trim hair, clean with just water, and dry University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet Page _____ of ______ completely). Tell pt to fold the patch so adhesive sides adhere to self, then flush patch to dispose. Make sure to remove old patch before putting on a new one. Inform that heat from fever or environment can increase patches medication delivery and can cause toxicity. 1/2009 N478 Drug Sheet University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Dilaudid (Hydromorphone) Class: Opiod Route and Dosage: Injection: 1, 2, 4, 10 mg/ml. Injection (powder): 250 mg/vial. Liquid: 5mg/5ml. Suppositories: 3 mg. Tablets: 2, 4, 8 mg. 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Binds with opiate receptors in the CNS, altering perception of and emotional response to pain. Suppresses cough reflex by direct action on cough center in medulla. Relieves pain and cough. Adverse Effects: Clouded sensorium, dizziness, euphoria, sedation, seizures, somnolence, bradycardica, hypotension, blurred vision, diplopia, nystagmus, constipation, nausea, vomiting, urine retention, bronchospasm, respiratory depression, induration with subq injections, and dependence. Drug Interactions: CNS depressants, general anesthetics, hypnotics, MAOIs, other opiod analgesics, sedatives, tranquilizers, TCAs, and alcohol. Effects on lab results: may increase amylase and lipase levels Consideration: Controlled Substance II. Use with caution in COPD pts and other respiratory problems. Drug may worse or mask gallbladder pain. Give drug before pain is intense. Mix drug in D5W, D5W NS, D5W ½ NS, ringers or lactated ringers. Give over 2 minutes. Respiratory depression and hypotension can occur. Monitor circulation and respirations. May increase adrenal insufficiency. Give one daily dose in morning. Give oral dose with food. Give IM deep into the gluteal muscle. Avoid subq injections. Don’t give high doses for more than 48 hours. Give potassium supplements. Patient Education: Teach pt signs of adrenal insufficiency University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet Page _____ of ______ (fatigue, muscle weakness, joint pain, fever, anorexia, nausea, dyspnea, dizziness, fainting). Don’t immediately stop. Warn about easy bruising. Tell to report sudden weight gain and warn of Cushionings. 1/2009 N478 Drug Sheet University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Darvocet (propoxyphene with acetaminophen) Class: nonnarcotic analgesic (NSAID) Route and Dose: Tablets A500=500mg acetaminophen and 100mg propoxyphene napsylate (1 tab q 4 hrs. max=8 in 24hr) N50=325 acetaminophen and 50 mg propoxyphene napsylate (2 tab q 4 hrs. max=12 in 24 hr) N100=650mg acetaminophen and 100 mg propoxyphene napsylate (1 tab q 4 hrs. max=6 in 24 hrs) 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Pain relief Adverse Effects: May cause sleepiness, and poor breastfeeding in infants. Large doses cause toxic psychosis. Excessive does often prove fatal. Nausea, vomiting, constipation, lightheadedness, drowsiness, headache, and vision changes. Drug Interactions: blood thinners, carbamazepine, MAOIs, other pain medications, TCAs, antianxiety drugs, antidepressants, antihistamines, anti-seizure drugs, medicine for sleep, muscle relaxants, psychiatric medicines, tranquilizers Effects on Lab Results: Consideration: Don’t prescribe to patients with suicidal tendencies, people with seizures, slow heart beat, abnormally low blood pressure, asthma attacks, COPD, and those already on medications that cause drowsiness. Patient Education: Don’t take more than prescribed. Lay down for 1-2hrs with minimal head movement may reduce upset stomach. Get up slowly when lying down or seated to reduce dizziness. May pass into breast milk. University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Toradol (ketorolac) Class: NSAID Therapeutic Class: analgesic and anti-inflammatory Route and Dose: Injection: 15 and 30 mg/ml Ophthalmic solution: 0.4% and 0.5% Tablets: 10 mg 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Relieves pain and inflammation. Short term management of pain, ocular itching caused by seasonal allergic rhinitis, post op inflammation following cataract surgery, pain and burning or stinging following corneal refractive surgery. Adverse Effects: Dizziness, drowsiness, headache, insomnia, syncope, edema, hypertension, palpitations, corneal edema, keratitis, ocular irritation, transient stinging and burning, diarrhea, dyspepsia, GI pain, nausea, hematuria, polyuria, renal failure, anemia, eosinophila, purpura, sweating, pain at injection site Drug Interactions: antihypertensives, diuretics, cyclosporine, lithium, blood thinners, methotrexate, Dong quai, feverfew, garlie, ginger, horse chestnut, red clover, st. johns wort. Effects on lab Results: May increase BUN and creatinine levels. May decrease hemoglobin and hematocrit. May increase eosinophil count and liver function test values. Consideration: May cause peptic ulcers, GI bleeding, perforation of the stomach or intestines. Increases risk of serious CV thrombotic events, MI, and stroke. Don’t exceed 120mg on day of transition when switching from IM to PO. IM use may cause pain at site. Apply pressure for 15-30 secs to minimize local effects. Duration of therapy shouldn’t exceed 5 days. Patient Education: Teach to recognize and report signs of GI bleeding. Don’t use drops while wearing contact lenses. Tell that it is short term use. University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Loratab (hydrocodone with acetaminophen) Class: non-salicylate analgesic and antipyretic Dose and Route: Lortab 2.5/500=500mg acetaminophen and 2.5 mg hydrocodone (1-2 q4-6hr. max=8 in 24hrs) 7.5/500=500mg acetaminophen and 7.5mg hydrocodone (1 q46hr. max=8 in 24hrs) 10/500=500mg acetaminophen and 10mg hydrocodone (1 q46hr. max=6 in 24hrs) Elixir=167mg acetaminophen 2.5mg/5ml hydrocodone (15ml q4-6hr. max=90ml/day 1/2009 N478 Drug Sheet INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT Page _____ of ______ NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT Relieve moderate to moderately Adverse Effects: lightsevere pain. headedness, dizziness, sedation, nausea and vomiting, drowsiness, mental clouding, lethargy, impairment of mental and physical performance, anxiety, fear, dysphoria, psychic dependence, mood changes, constipation, Ureteral spasm, spasm of vesical sphincters and urinary retention, respiratory depression,hearing impairment or permanent loss, skin rash, and pruritus, allergic reactions, rash, thrombocytopenia, agranulocytosis Drug Interactions: narcotics, antihistamines, antipsychotics, antianxiety agents, or other CNS depressants (including alcohol), MAOIs or TCAs EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Effects on lab results: may produce false-positive test results for urinary 5-hydroxyindoleacetic acid. Consideration: Respiratory depression, increased intracranial pressure. Narcan can reverse an overdose. 10g is considered toxic for adults. Patient Education: Don’t take with alcohol. Lay down for 1-2 hrs with minimal head movement to decrease nausea. Taking with food may decrease effectiveness. Don’t suddenly stop if you have taken for an extended amount of time. Use caution engaging in activities requiring alertness such as driving or using machinery. To minimize dizziness and lightheadedness, get up slowly when rising from a seated or lying position. University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Percocet (oxycodone with acetaminophen) Class: non-opiate, nonsalicylate analgesic and antipyretic Route and dose: Percocet 2.5 mg/325 mg The usual adult dosage is one or 2 tablets every 6 hours. The total daily dose of acetaminophen should not exceed 4 grams. Percocet 5 mg/325 mg; Percocet 7.5 mg/500 mg; Percocet 10 mg/650 mg The usual adult dosage is one tablet every 6 hours as needed for pain. The total daily dose of acetaminophen should not exceed 4 grams. Percocet 7.5 mg/325 mg; Percocet 10 mg/325 mg The usual adult dosage is one tablet every 6 hours as needed 1/2009 N478 Drug Sheet INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT Page _____ of ______ NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT Relieve moderate to moderately Adverse Effects: Nausea, severe pain. vomiting, constipation, lightheadedness, dizziness, drowsiness, flushing, vision changes, or mental/mood changes Drug Interactions: opioid analgesics, general anesthetics, phenothiazines, other tranquilizers, centrally-acting anti-emetics, sedativehypnotics or other CNS depressants (including alcohol), and Agonist/antagonist analgesics Drug/Drug Interactions with Acetaminophen: Alcohol, ethyl, Anticholinergics, Contraceptives, Charcoal, Beta Blockers, Loop diuretics, Lamotrigine, Probenecid, Zidovudine EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Effects on lab results: may cross-react with assays used in the preliminary detection of cocaine or marijuana in human urine. may interfere with home blood glucose measurement systems; decreases of > 20% in mean glucose values may be noted Consideration: Risk for abuse. Respiratory depression (may need narcan). Use with caution in pts with respiratory problems. May produce orthostatic hypotension. Increases intracranial pressure. Patient Education: Keep in a secure place out of the reach of children. In the case of accidental ingestions, emergency medical care should be sought immediately. Unused tablets should be destroyed by flushing down the toilet. May impair mental and/or physical ability required for the University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet for pain. The total daily dose of acetaminophen should not exceed 4 grams. 1/2009 N478 Drug Sheet Page _____ of ______ performance of potentially hazardous tasks (e.g., driving, operating heavy machinery). Don’t take with alcohol. May be passed in breast milk. Don’t abruptly stop medication after using for a few weeks. Potential drug of abuse. University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Demerol (meperidine) Pharmacologic class: opioid Therapeutic class: analgesic, adjunct to anesthesia For moderate to severe pain: adults receive 50-150 mg PO, IM, or SubQ every 3-4 hours, prn Or 15-35 mg/hour by continuous IV infusion; children receive 1.1-1.75 mg/kg PO, IM, or SubQ, up to the adult dose, every 3-4 hours, prn 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Relief of pain Assess patient’s pain before therapy and regularly thereafter to monitor drug effectiveness; Monitor patient for increased toxic effect, especially in a patient with renal impairment; May be used in patients with pain who are allergic to morphine; If respiratory rate is less than 12 breaths/minute, if respiratory depth decreases, or if pupil size decreases, don’t give drug; Oral dose is less than half as effective as parenteral dose; give IM if possible; when changing from parenteral to oral rout, increase dose; Syrup has local anesthetic effect; give with full glass of water; Subcutaneous injection is painful; avoid if possible Effects on lab values: May increase amylase and lipase levels Outcome: Patient is free from pain Patient doesn’t experience injury Patient and family state understanding of drug therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet Page _____ of ______ MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT Phenergan (promethazine) Prevents motion sickness and relieves nausea, nasal congestion, and allergy symptoms. Also promotes calmness Assess patient’s condition before starting therapy and regularly thereafter to monitor drug’s effectiveness Pronounced sedative effect limits use in many ambulatory patients Give drug with food or milk to reduce GI distress;Check patient for sulfite allergy before giving Phenergan IM; Inject IM deep into large muscle mass, rotate injection sites; Do not give Sub Q; Drug may be safely mixed with Demerol in the same syringe; In children it is especially important to monitor respiratory depressant effects and avoiding combining the drug with other drugs known to have respiratory depressive effects; Warn patient about photosensitivity and precautions to avoid it Pharmacologic class: phenothiazine derivative Therapeutic class: antiemetic, antihistamine, sedative For nausea and vomiting: adults receive 12.5 to 25 mg PO, IM, or PR every 4 hours, prn; Children older than age 2 receive 0.5 mg/kg 1/2009 N478 Drug Sheet EVALUATION OF DESIRED EFFECT FOR THE PATIENT. INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Effects on lab values: May increase glucose and hemoglobin levels and hematocrit May decrease WBC, platelet, and granulocyte counts May have false-positive or false-negative results with urine pregnancy tests May interfere with blood typing of ABO group University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet MEDICATION WITH PRESCRIBED DOSEAGE CLASSIFICATION OF THE DRUG USUAL DOSE/SAFE DOSE AND ADMINISTRATION Morphine sulfate Pharmacologic class: opioid agonist Therapeutic class: analgesic For severe pain: adults receive 5 to 20 mg/70kg SubQ or IM every 4 hours, prn Or 10 to 30 mg PO every 4 hours prn Or 10 to 20 mg PR every 4 hours prn Or 15 to 30 mg of controlledrelease tablets PO every 8 to 12 hours Or 5 mg of epidural injection by epidural catheter (maximum total epidural dose is 10 mg). If adequate pain relief is not obtained within 1 hour, give additional doses of 1-2 mg at intervals sufficient to assess effectiveness. Children receive 0.1 to 0.2 mg/kg IM or SubQ every 4 hours, prn. Maximum single dose is 15 mg. Or, 0.05 to 0.1 mg/kg by slow IV injection 1/2009 N478 Drug Sheet Page _____ of ______ INDIVIDUAL DESIRED EFFECT OF DRUG FOR THIS PATIENT NURSING IMPLICATIONS/ CONSIDERATIONS FOR THIS PATIENT Relieves pain Assess patient’s pain before therapy and regularly thereafter to monitor drug effectiveness; Drug may worsen or mask gallbladder pain; Monitor patient for respiratory depression after administration; Assess patient for constipation often; adjust GI drugs as needed when increasing morphine dose; Keep opioid antagonist and resuscitation equipment available; If respiratory rate is below 12 breaths/minute except in terminal conditions, don’t give the dose. Notify prescriber; Because constipation is often severe with maintenance dosage, give stool softener or other laxative Warn patient about getting out of bed or walking without assistance. EVALUATION OF DESIRED EFFECT FOR THE PATIENT.INCLUDING ASSESSMENT, LAB RESULTS AND PROCEDURES Effects on lab values: May increase amylase level May decrease platelet count Outcomes: Patient states that pain is relieved Patient maintains adequate breathing patterns throughout therapy University of Evansville Department of Nursing and Health Sciences Drug Dispensing Sheet 1/2009 N478 Drug Sheet Page _____ of ______