Connective Tissue • The dense layer of the basal lamina of all epithelial tissue is created by connective tissue. • Connective tissue connects the epithelium to the rest of the body. Three Basic Components 1. Specialized cells – Fibroblasts – Adipocytes 2. Extracellular protein fibers – Collagen fibers – Reticular fibers – Elastic fibers 3. A fluid known as ground substance Functions of Connective Tissue • • • • Establishing a structural framework for the body. Transporting fluids and dissolved minerals. Protecting delicate organs. Supporting, surrounding, interconnecting other types of tissue. • Storing energy reserves • Defending the body from invading microorganisms. Classification of Connective Tissues Classified based on their physical properties. Three categories: • Connective Tissue Proper – Ex. Adipose tissue • Fluid Connective Tissue – Ex. Blood and Lymph • Supportive Connective Tissue – Ex. Cartilage and bone Connective Tissues Connective Tissue Proper LOOSE Fibers create loose, open framework. “Packing materials” • Adipose • Areolar • Reticular DENSE Fibers densely packed • Dense regular • Dense Irregular • Elastic Fluid Connective Tissues BLOOD LYMPH Contained in cardiovascular system Contained in lymphatic system Supporting Connective Tissues CARTILAGE Solid, rubbery matrix • Hyaline • Elastic • Fibrocartilage BONE Solid, crystalline matrix Mesenchyme Tissue • Function: Give rise to all other connective tissues of an embryo and all various cell types of adult connective tissue. • Found in abundance during early development of most animals. Loose Connective Tissue • Adipose Tissue – Location: Deep to the skin, especially at sides, buttocks, padding around eyes and kidneys – Function: Provides padding, insulates, stores energy • Areolar Tissue – Location: Under skin, in or around mucous membranes, around blood vessels and nerves – Functions: provides padding, binds the outer layer to the muscles beneath. Dense Regular Connective Tissue Ex. Tendons and Ligaments • Locations: Between skeletal muscles and skeleton; between bones or internal organs • Functions: Provides firm attachment, conducts pull of muscles, reduces friction Elastic Tissue • Location: Between vertebrae of the spinal column; in blood vessel walls • Functions: Stabilizes positions of vertebrae; cushions shocks Cartilage • The matrix of cartilage is a firm gel that contains polysaccharide derivatives • Chondrocytes- Cartilage cells, the only cells in the cartilage matrix • Lacunae- Small chambers that cartilage cells occupy Hyaline Cartilage • Locations: Between tips of ribs and bones of sternum; supporting larynx, trachea, and bronchi • Functions: Provides stiff but flexible support, reduces friction between bony surfaces Elastic Cartilage • Locations: In the ear and in the trachea • Functions: Provides support, but tolerates distortion without damage and returns to original shape Fibrous Cartilage • Locations: Pads within knee joint; between pubic bones of pelvis; intervertebral discs • Functions: Resists compression; prevents bone-to-bone contact; limits relative movement