Digestive System Chapter 14 Digestive system Divided into two parts: 1. Alimentary canal (aka GI tract) – Path that the food takes through the body – Performs all digestion functions (ingest, digest, absorb, defecate) – In a cadaver the length is about 9-10m • Shorter when living….Why? – Organs included? Digestive System 2nd part = Accessory organs – Assist in the digestive system process in various ways – Organs included: Teeth, Tongue, Salivary Glands, Liver, Gallbladder, Pancreas, Spleen Mouth aka Oral Cavity Where food enters the body and digestion begins here. – How? Teeth (mechanical) and saliva (chemical) What role do the following play in the mouth? – Lips, cheeks, uvula Tongue Mostly muscle tissue – What type of muscle would it be? Frenulum – connects the tongue to the bottom of the mouth – What could be a problem if this is too short or long? What is the purpose of the tongue? Taste and move food around Papillae – rough projections that contain taste buds – Why would these be rough? Four types of taste buds – sweet, sour, salt, bitter Palate 2 sections Hard Palate – What bone would make this up? – Anterior Portion Soft Palate – Posterior Portion – mostly a muscular arch – This and the uvula are drawn up during swallowing • Why is this important? Blocks off the nasal passage during swallowing Tonsils Play a role in the defenses of the body Two types: Lingual – at the base of the tongue – Used as anchor, covered by lymphatic tissue Palatine – Located on the posterior sides of the tongue – These are the ones removed when you have tonsilitis Teeth Used to mechanically breakdown food – aka masticate, aka chewing 2 sets Primary (baby) – 10 on each jaw – What happens to these? They are lost – The roots are resorbed and teeth are pushed out by secondary teeth Secondary (permanent) – 16 on each jaw – Begin to appear around age six Secondary Teeth Incisors – 8, front teeth – Function? Cuspids (Canine) – 4, sharper teeth (fangs) – Function? Bicuspids (premolar) – 8, behind cuspids, a bit flatter – Function? Molars – total of 12, back teeth, much flatter (4 first, 4 Second, 4 Third) – Third also known as wisdom teeth – Function? Tooth Structure Crown – above gums Root – below gums Enamel – – Hardest substance in the body (but brittle) and cannot be replaced – What problem does this pose? Pulp cavity – Blood supply and nerves Dentin – deep to the enamel and surrounds the pulp cavity Salivary Glands Main Secretions – Amylase – breaks down large starch and glycogen molecules – Mucus – •What is its purpose? Bind food particles and lubricate alimentary canal What triggers secretions? Autonomic nervous system Salivary Glands – 3 different glands Parotid – Located anterior and inferior to the ear – Secretes saliva rich in amylase Submandibular – Located where? – Secretes thicker saliva than parotid. •Why thicker? Sublingual – Located where? – Secretes primarily mucus Pharynx Connects nasal and oral cavities with the esophagus Contains the epiglottis – What is this? Flaplike structure used to seal off trachea during swallowing. Performs the swallowing reflex Oral Cavity ?’s In comparison to bone, why is enamel stronger and more brittle? Differentiate between the parotid, submandibular, and sublingual salivary glands. Why would it be a problem if the tongue was not skeletal muscle tissue? Why is the uvula important? (2 reasons) Describe the teeth of a 12 year old girl. Steps of Swallowing Soft palate raises Hyoid and larynx raise causing the epiglottis to close off larynx Tongue compresses against the soft palate, sealing the oral cavity from the pharynx Longitudinal muscles pull the pharynx up toward the food Muscles of the lower pharynx relax to open the esophagus Peristaltic wave forces food into the esophagus Peristalsis Wall Structure The rest of the alimentary canal is really just a long coiled tube with 4 layers. Mucosa –inner most layer – Secretes mucus and enzymes Submucosa – contains blood vessels – Carries nutrients to surrounding tissues but also nutrients away during absorption. Muscular layer – contains circular and longitudinal muscles – Moves food through the system Serosa – outer layer, secretes serous fluid – Why is this important? Esophagus Connects pharynx to stomach – Function? Found posterior to the trachea Ends at cardioesophageal sphincter – What is a sphincter? Ring of muscle that is contracted unless opened for physiological function – This one connects the stomach and the esophagus, what will its function be? – What will happen if it is not functioning all the way? Stomach Found on the upper left side of the abdominal cavity What happens in the stomach? – Food is mixed with gastric juices to promote chemical digestion, very little absorption Size is small when empty, yet it can hold up to 4 liters of food. – How? Interior of stomach is lined with large folds called rugae – These unfold and the stomach has more area Stomach Regions of the stomach •Cardiac – near cardioesophageal sphincter •Fundic – anterior portion (curvature above ces) •Body – Main region •Pyloric – posterior portion, near pyloric sphincter Stomach ends at Pyloric Sphincter – What does this control? Gastric Juice 4 Components – Pepsin – main component – digests protein – Pepsinogen – inactive form of pepsin – Hydrochloric Acid – converts pepsinogen to pepsin – Mucus – lubrication and protection Regulated by autonomic nervous system When this is mixed with food it is called chyme Small Intestine The largest part of the alimentary canal – Anywhere from 2.5m to 7m in length 4 major functions: Receives secretions from the pancreas and liver Completes digestion of chyme Absorbs products Transports residues to large intestine Small Intestine 3 subdivisions – Duodenum - smallest section, comes just after stomach • Receives food from stomach, and secretions from pancreas and and liver/gallbladder – Jejunum – middle section • Continues digestion, most absorption takes place here – Ileum – last and largest section • Prepares residue for large intestine Small Intestine Walls are well suited for absorption Have folds, villi, and microvilli – What are these going to do? Greatly increase surface area Pancreas Located near posterior abdominal wall inferior to stomach 3 important functions Secretes pancreatic juice into the duodenum. (where is this?) – PJ contains amylase, lipase and nuclease • What are these and what will these do? – PJ is also very basic (high pH) • Why is this important? What other important function? Liver Located in superior medial part of abdominal cavity Very large and lobed (largest gland in body) One of the most important glands in the body Multiple Functions (thought to have over 500) – Many having to do with the filtering and regulation of many compounds in the blood Digestive functions Produce and secrete bile (huge in digestion of fats) Secretes it into the duodenum Bile Consists of: 1. Water 2. Bile pigments Two types biliverdin (green) and bilirubin (yellow) Which one is bad? 3. Bile salts Only part of the bile that has digestive function Emulsification 4. small amounts of other compounds (electrolytes, cholesterol, phospholipids) Gallbladder Storage area – What do you think it stores? Bile (between meals) – Reabsorbs water to concentrate it If stored too long, gall stones may form Large Intestine Shorter than the small intestine (~1.5m) Begins at cecum, ends at anus (has two sphincters) – Why would it have two? Divided into four sections: ascending, transverse, descending, sigmoid colon Lacks villi Little digestive function – absorbs water and electrolytes – Eliminates food residue as feces Questions If a person had a condition which limited their ability to produce hydrochloric acid in the stomach, how might this affect digestion and why? Why would it be a problem if a person’s intestinal walls were completely flat? Why would storing bile for too long in the gall bladder cause gallstones? What would result if a person did not produce much mucus in the stomach? Thinking about the contents of the stomach, what might happen to a person with a cardioesophageal sphincter that does not close completely? Disorders of the Digestive system What are these disorders and what causes them? – Diarrhea – Peptic Ulcers – Emesis – Constipation – Pancreatitis – Heartburn – Diverticulosis – Jaundice