Interdisciplinary
Biomedical Engineering
Research
at the
University of Florida
College of Engineering at a Glance
• 275 faculty, 4600 undergraduate students, 1900
graduate students
• 900 BS, 600 MS, 140 PhD per year
• $90M research expenditures
• 11 academic departments
• Engineering in biology and medicine
• New Department of Biomedical Engineering – July
2002
Evolution
into
Epilepsy
Researchers from the
College of Engineering,
the College of Medicine and
the Department of the Navy
are working together to find a
method of predicting and
controlling epilepsy-triggered
seizures.
The NIH recently awarded the
team a $1.4, 4-year grant.
[PI: Dr. William L. Ditto
NIH 1R01EB004752-01]
Dr. William L. Ditto, PI — Biomedical Engineering
Dr. Paul R. Carney — Pediatric Neurology
Evolution into
Epilepsy:
A dream team of researchers from the
University of Florida and Shands at UF.
Dr. Thomas B. DeMarse — Biomedical Engineering
Dr. Thomas Mareci — Biochemistry & Molecular Biology
Dr. J. Chris Sackellares — Biomedical Engineering
Dr. Justin C. Sanchez — Pediatric Neurology
Dr. Mark C. Spano — Department of the Navy
Michael D. Furman — Biomedical Engineering
Jennifer Simonotto — Biomedical Engineering
Evolution into Epilepsy
image data
raw data
EEG /
histology
analysis
mea data
Brain Dynamics
Bioengineering
Research
Partnership
The mission of the Brain
Dynamics Bioengineering
Research Partnership is to develop
an online, real-time automated
seizure warning and
prevention system for use by
epileptic patients and their
caregivers.
[PI: Dr. J. Chris Sackellares
NIH NIBIB R01EB002089]
Brain Dynamics Bioengineering
Research Partnership
Dr. J. Chris Sackellares, PI
Biomedical Engineering
Dr. Paul R. Carney
Pediatric Neurology
Dr. Panos M. Pardalos
Industrial & Systems
Engineering
Dr. José C. Principe
Electrical & Computer
Engineering
Dr. Deng-Shan Shiau
Neuroscience
Dr. Mark C. Yang
Statistics
Dr. Leonidas D. Iasemidis
Arizona State University
Optical Imaging
of Breast Cancer
Huabei Jiang, a widely known innovator
in the field of optical imaging, is
supported by a 5-year, $1.4 million
grant awarded to him in 2002 by the
National Institutes of Health.
He's developing a relatively painless,
non-invasive technique to detect breast
cancer. Instead of allowing their breasts
to be compressed between two plastic
plates and held firmly in place, as in a
mammogram, patients in Jiang's study
lie face down on a special exam table. An
array of fiber optics gently surround the
breasts and project near-infrared light at
different angles
Dr. Huabei Jiang, PI
Biomedical Engineering
Stephen Grobmyer
Department of Surgery
[NIH R01CA090533]
Monitoring
Intraperitoneal
Bleeding
Bleeding in the abdominal cavity is a
frequent consequence of the blunt
trauma suffered in motor vehicle
accidents. Often it is undetected by
conventional clinical screening
techniques. Rosalind Sadleir’s group
has developed a monitoring method
that can quantify the rate of bleeding
and thus the urgency of surgery. Now,
they’re readying a new commercial
device for clinical trial.
Dr. Rosalind Sadleir, PI
Biomedical Engineering
Dr. Edward Ross
Medicine (Nephrology)
Advanced Magnetic
Resonance Imaging
and Spectroscopy
Facility
AMRIS is a state-of-the-art NMR
facility for high-resolution solution
NMR, solid-state NMR,
microimaging, animal imaging and
human imaging.
AMRIS currently has seven spectrometer
systems, including a 750 MHz wide bore,
an 11 T/40 cm bore horizontal animal
imaging magnet, and two 3T human
systems. AMRIS was developed in part
through a grant from the Department of
Defense. An external users program in
AMRIS is supported by the National High
Magnetic Field Laboratory through funds
from the National Science Foundation.
Dr. Arthur Edison, Director
Advanced
Magnetic
Resonance
Imaging and
Spectroscopy
Facility
Faculty at the
University of
Florida
Dr. Steve Blackband — Neuroscience
Dr. C. Russell Bowers — Chemistry
Dr. Ioannis Constantinidis — Medicine
Dr. Bruce A. Crosson — Clinical & Health
Psychology
Dr. Arthur Edison — Biochemistry &
Molecular Biology
Dr. Jeffrey R. Fitzsimmons — Radiology
John Forder — Radiology
Huabei Jiang — Biomedical Engineering
Dr. Peter Lang — Clinical & Health
Psychology
Dr. Yijun Liu — Psychiatry
Dr. Joanna Long — Biochemistry &
Molecular Biology
Dr. Thomas Mareci — Biochemistry &
Molecular Biology
Ilona Schmalfuss — Radiology
Krista Vandenborne — Physical Therapy
Glenn Walter — Physiology
Norbert Wilke — Radiology (Jacksonville)
Bio-erodable Micro-porous
Polysaccharide Foams Scaffolds
Biomaterials
Research
Spinal Cord Regeneration in rats using a
Combination of Polymer Scaffolding and
Microglia Cells
Research supported by the Christopher
Reeves Foundation
Goldberg (Materials Science) and Streit
(MBI)
Nano-particles
for Medical
Applications
A specially designed particle, quantum
dot based contrast agent,
that is paramagnetic, fluorescent, and
radio-opaque
Potentially useful as a biomarker for
imaging and surgery
Santra (PERC), Moudgil (MSE, PERC),
Holloway (MSE), Mercle
(Neurosurgery), Walter (Neurosurgery)
Gross view
Fluorescent
Radio-opaque
(a)
1.5x10
(b)
-5
300K
1.0x10
Magnetization(emu)
5.0x10
-5
-6
0.0
-5.0x10
-1.0x10
-1.5x10
-6
Paramagnetic
-5
-5
-1000
-750
-500
-250
0
H(Gauss)
250
500
750
1000
(c)
(a) and (b) represent dorsal
views and (c) represents
coronal section
Brain Machine
Interfaces
UF Collaboration with Duke and MIT
The CNEL Lab (Principe, Harris)
designs models which “decode”
neuronal activity into motor
commands for prosthetics
Models are implemented in low
power, hybrid (analog VLSI-DSP)
chips
IT for Medical
Applications
Assistive Environments for Successful
Aging (GatorTech Smart House)
Radiation Treatment and Planning - Dose
computation, Leaf sequencing
Medical Imaging
Bioinformatics
Preserving a `Hands-on’ Knowledge Base
of Essential but Rare Surgical Procedures
Interdisciplinary
Bioimaging &
Bioengineering
Building
The proposed facility will house and
integrate the biomedical-focused
groups within one 275,000 square foot
building to create completely new
research and funding opportunities.
The physical and cultural integration of
researchers within this building will provide
synergistic and collaborative environments
that will establish UF as a leader in
interdisciplinary biomedical science,
engineering, technology, translational
research and technology transfer. A state-ofthe-art animal care facility in the same
building will add to the synergy and allow UF
researchers access to the finest biomedical
research infrastructure in the world.
Interdisciplinary Bioimaging & Bioengineering
Building
Biological Imaging Center
[70,000 sq. ft.]
- Clinical translational research
- Technology Liaison Office
- Structural Biology and
Molecular Biophysics
Brain Research Labs
[50,000 sq. ft.]
- New programs for
brain/neuroscience
Department of Biomedical
Engineering
[75,000 sq. ft.]
- Administrative offices
- Research labs
Animal Care Facility
[62,000 sq. ft.]
Support Programs & Public
Space
[18,000 sq. ft.]