Evaluation of Scrotal Pain 1.4.11 Case Conference

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Case Conference

Vincent Patrick Tiu Uy

PGY-1

January 4, 2011

General Data

17 year old male with scrotal pain

History of Present Illness

(+) Testicular pain, bilateral, with no radiation to the inguinal area, graded 3-4/10, more pronounced when standing, relieved by sitting

(+) Difficulty in walking

(-) Dysuria, penile discharge, hematuria

No medications taken

Denies history of trauma to the groin

No prior history of testicular pain

Consult to Emergency Department

History

Review of Systems

Unremarkable. Most mentioned in the HPI

Past Medical

History

Family History

Social History

Insomnia (?) taking Seroquel, no previous hospitalizations, no previous surgeries, NKDA

Denies any medical/surgical problems among immediate family members

Child lives in an apartment with parents and siblings. No pets at home. No recent travel.

Denies any introduction of new foods. Child feels safe at home. Admits to prior sexual activity with 1 female partner. Denies smoking, alcohol and illicit drug use.

Physical Examination

General Appearance Alert and awake, prefers to sit

Vital Signs

Head, Eyes, Ears, Nose Throat,

Neck

T 98 HR 102 RR 20 BP 122/79 SO2 98% RA

NCAT, pinkish conjunctivae, anicteric sclerae, nasal septum midline, TM’s intact, dry oral mucosa, nonhyperemic OP, supple neck, no CLAD

Chest and Cardiovascular

Abdominal Exam

GU/Rectal

Extremities

CTAB, +S1/S2, no murmurs

Flat abdomen, hypoactive bowel sounds, no tenderness, no palpable masses, (-) rebound, (-)

Rovsing’s sign, (-) Psoas sign, (-) Obturator sign, (-)

Murphy’s sign

Tanner V, no penile discharge nor erythema of the tip.

Uncircumcised. B/L descended testes. No obvious discoloration of the scrotum. (+) tenderness to palpation of both testes. No Phren’s sign, no blue dot sign and no “bag of worms”. Transillumination negative for fluid.

No edema, no cyanosis, brisk capillary refill

Differentials?

Management in the ED

STAT Scrotal Ultrasound

Urinalysis – normal

Urine sent for culture – normal

Urine GC/Chlamydia sent - negative

Scrotal Ultrasound

Scrotal Ultrasound

Scrotal Ultrasound

Scrotal Ultrasound

Impression/Disposition

Signed off as a case of Epididymitis + Small Varicocoele

Pain relief + Prophylactic antibiotics

Evaluation & Management of Children with Testicular Pain or Swelling

Anatomy of the Testis

Key Questions in the History

Characteristic of the pain Recurrent pain suggests torsion

History of trauma

History of change in the size of the testicle

Changes during Valsalva suggests communicating hydrocoele or varicocele

Sexual history

Difficulty voiding urine

STD’s can cause epididymitis

Suggests intraabdominal mass (hernia), UTI, neurologic problems or spinal cord disease

Flank pain or Hematuria Suggests kidney stone with referred pain to the scrotum

Suggests testicular torsion Abdominal pain with diminished appetite, nausea and vomiting

Focused Exam

Inspection

Palpation

Cremasteric Reflex

Phren’s sign

Blue dot sign

Inspection

Inspect while the patient is standing – check the penis, pubic hair and inguinal areas.

Inspect for ulcers, papules, pubic hair infestations or lymphadenopathy

Does the patient have any tattoo? Piercings?

Inspection

The left testicle is slighlty lower than the right

Palpation

Roll the testicle between thumb and forefingers to look for masses

Palpate for the epididymis and go up towards the spermatic cord.

Transilluminate the scrotum if swelling is suspected.

Predicting Testicular Size

Cremasteric Reflex

Stroking the upper thigh results in elevation of the ipsilateral testicle.

Usually present in boys

30 months to 12 years

Less reliable in teenagers and infants

Phren’s Sign

Elevation of the scrotal contents relieves pain in patients with epididymitis and not with testicular torsion.

POSITIVE SIGN – Relief of pain with elevation =

EPIDIDYMITIS

Not a reliable exam in most situations.

Blue Dot Sign

Almost always suggestive of torsion of the appendix testis.

Additional Tests

Test

Complete Blood Count

Urinalysis and Culture

Purpose

Elevated WBC count in torsion

Test usually obtained for pre-operative purposes

R/o UTI

Pyuria may be seen in Epididymitis

R/o sexually transmitted diseases Gram stain, culture, rapid molecular amplification testing of urethral discharge

-or-

Nucleic amplification test of urine

Color Doppler Ultrasound of the

Scrotum

Check perfusion

R/o torsion if cannot be excluded on clinical grounds

Differential Diagnosis

Testicular Torsion

Torsion of Appendix

Testis

Epididymitis/Orchitis

Trauma

Incarcerated Inguinal

Hernia

Henoch-Schoenlein

Purpura

Referred Pain

Non-specific

Differential Diagnosis

Hydrocoele

Varicocoele

Spermatocoele

Testicular Cancer

Torsion of the Testicle

Inadequate fixation of the testis to the tunica vaginalis through the gubernaculum

“Bell-clapper” deformity

Twisting of the spermatic cord

Venous compression and edema

Ischemia

Torsion of the Testicle

Peak incidence in the neonatal period and the pubertal period

~65% occur during the 12-18 year old range due to increasing weight of the testicles

Torsion of the Testicle

Abrupt onset of severe testicular or scrotal pain

<12 hours of duration

90% have associated nausea and vomiting

Pain can be constant unless the testicle is torsing and detorsing

Most boys report a previous episode in the past

Torsion of the Testicle

Diagnosis is made clinically. Impression is stronger if there are previous episodes

Doppler ultrasound should be done if there are uncertainty in diagnosis

False positive scans (diminished blood flow)

Large hydrocoeles

Abscess

Hematoma

Scrotal hernia

False negative scans

Spontaneous detorsion or Intermittent torsion-detorsion

Torsion of the Testicles

Timing of operation

4-6 hours (100%)

>12 hours (20%)

>24 hours (0%)

The contralateral testis should also be explored;

“bell-clapper deformity” is usually bilateral

Surgical Detorsion +

Orchiopexy

Orchiectomy if non-viable

Torsion of the Appendix

Testis/Epididymis

Pedunculated shapes of these structures predispose them to torsion

Occurs most commonly in 7-12 year old boys

Torsion of the Appendix

Testis/Epididymis

Pain is of sudden onset, similar to testicular torsion

The testicle is non-tender, but there is a tender localized mass usually at the superior or inferior pole

(+) Blue dot sign – gangrenous appendix

Doppler ultrasound may be necessary to rule out testicular torsion – will show a lesion of low echogenicity. Blood flow to the affected area may be increased

Radionuclide scan may show the “hot dog” sign of the torsed appendage.

Torsion of the Appendix

Testis/Epididymis

Management

Bed rest, Analgesia, Scrotal Support

Resolution

5-10 days out patient

No follow-up necessary

Surgery

Removal of the appendage; exploration of contralateral testis not necessary

Epididymitis

Inflammation of the epididymis

Occur more frequently in late adolescent boys and even in younger males who deny sexual activity.

Risk factors

Sexual activity

Heavy physical exertion

Direct trauma

Bacterial epididymitis – think of anatomical abnormalities

Epididymitis

(+) Sexual activity

Chlamydia

N. gonorrhea

E. coli

Viruses

Ureaplasma

Mycobacterium

CMV

Cryptococcus (HIV)

(-) Sexual Activity

Mycoplasma

Enteroviruses

Adenovirus

Epididymitis

Acute or subacute onset of testicular pain

History of urinary frequency, dysuria, and fever

Normal vertical lie on exam, scrotal erythema, (+) scrotal edema, inflammatory nodule

Normal cremasteric reflex, with negative Prehn’s sign

Epididymitis

Doppler ultrasound may be necessary to rule out testicular torsion

All patients should get a urinalysis and urine culture

CDC guidelines in sexually active boys

Gram-stained smear if urethral exudates or intrautheral swab specimen or Nucleic amplification test

Urine culture of a first void urine

RPR and HIV testing

Epididymitis

ADMSSION

CRITERIA

Doubt diagnosis

(?Torsion)

Severe pain

CHILDREN

(+) Leukocytes in urine

Empiric antibiotics –

Bactrim*/Keflex*

Immunocompromised (-) Leukocytes in urine

Unreliable patient

Supportive treatment

[NON-BACTERIAL]

Non-compliance

SEXUALLY ACTIVE

Ceftriaxone x 1 +

Doxycycline x 10 days

Ofloxacin

Levofloxacin

• It is equally important to treat sexual partners if an STD is the likely cause.

• Supportive therapy: Scrotal support, bed rest and NSAIDS

Other Causes & Clues

CAUSES

Trauma

CLUES & MANAGEMENT

• Rarely – compression of the testis against the pubic bone from straddle injury  Testicular rupture

• Hematocoele  Intratesticular hematoma

• Color doppler may diagnose the abnormality

• Audible bowel sounds in the scrotum Incarcerated Inguinal

Hernia

Henoch-Schonlein

Purpura

Orchitis

• Nonthrombocytopenic purpura, arthralgia, renal problems, abdominal pain, GI bleeding

• Treatment is supportive  bleeding in the GIT is more priority in management

• Usually viral (Mumps, Rubella, Coxsackie,

Echovirus)

• Brucellosis

• Pain and tenderness of the testis with peculiar shininess of the scrotal surface

• Symptomatic treatment  rest and ice packs,

NSAIDS

Other Causes & Clues

CAUSES

Referred Pain

Nonspecific Scrotal

Pain

CLUES & MANAGEMENT

• Other signs and symptoms may be apparent

• Examples include:

• Urolithiasis

• Nerve root impingement

• Retrocecal appendicitis

• Tumor

• Mild scrotal pain in the light of a normal exam

• Imaging is not necessary

• Treatment is not necessary

Scrotal Swelling

Scrotal Swelling History & PE

Hydrocele

Varicocele

Spermatocele

Testicular CA

• (+) Transillumination

• Increase in size during the day or with Valsalva

• If non-communicating, no change in size.

• The spermatic cord has a “bag of worms” feeling secondary to vessel dilation

• The varicoceles may be more palpable with standing or with Valsalva

• (-) Transilluminate

• Painless, fluid filled cyst on the head of the epididymis

• (+) Transillumination localized to the head of the testis

• Firm, painless mass that does not transilluminate

• (+) Reactive hydrocele

Brain Teaser

An 18 year old male was seen in the ED for scrotal pain of 1 day.

He denied previous episodes before. He recently recovered from a febrile

“infection” about a week ago.

Patient is sexually active with female partners. On exam, the testes were not enlarged, (+) tender to palpation B/L,

Prehn’s sign was negative, no blue dot sign noted. Urinalysis showed leukocyte esterase and nitrites with pyuria. The ED attending asks you : “What’s the plan?”

A. No additional test is needed – treat empirically with Ceftriaxone and

Doxycycline

B. Test for STD’s like

Chlamydia and Gonorrhea

C. Send the urine for culture and sensitivity

D. Scrotal ultrasound to immediately rule out torsion.

E. Admit the patient and annoy the floor team

Brain Cruncher

A 16 year old male was seen in the ED for acute onset of scrotal pain.

On further questioning, he has had prior episodes of scrotal pain which lasted for only 2 minutes on the average.

The astute ER attending got a urinalysis and scrotal ultrasound.

The final diagnosis was testicular torsion.

To alleviate the patient’s anxiety as to benefit of immediate surgery, what should the ED attending ask the patient at this point?

A. “Where exactly is the pain?”

B. “What is the quality of the pain?”

C. “Was there any trauma to the groin?”

D. “What time did the pain happen?”

E. “Did you take any pain reliever and did it help with the pain somehow?”

Thank you!

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