Non-Scaling FFAG gantry for proton/carbon gantry Dejan Trbojevic-BNL, Eberhard Keil-CERN, and Andrew Sessler-LBL • Introduction – Motivation for a new way of isocentric gantry design • Carbon/proton gantries today–(Heidelberg, PSI, …) • Spot scanning – alternative option • The non-scaling FFAG gantries: – Smaller proton gantry – Carbon/proton gantry • Engineering design – magnets are available • Summary September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 1 MOTIVATION: large weight of the present gantries • Large Br=6.76 Tm for carbon ions requires large magnetic fields. • Presently the beam scanning requires very large magnet at the end of the gantry to accommodate parallel beams to the patient. • Results are: very large magnets and large weight of the transfer line and the whole support. The carbon/proton cancer therapy facilities constraints are very difficult to fulfill with the warm temperature magnets. • This leads us to a new concept – non-scaling light small superconducting gantry. September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 2 Carbon Gantry in Heidelberg Weight of the transport components – 135 tons Total weight = 630 tons Length of the rotating part =19 m Carbon Ek=400 MeV/n Br = 6.76 Tm If: B=1.6 T then r ~ 4.2 m If: B=3.2 T then r ~2.1 m September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 3 Munich and PSI proton gantries September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 4 Proton Gantry at PSI 1.27 m 7.4 m September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 5 The proton gantry @ PSI counterweight 110 tons September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 6 Simulation Code: “SRNA” Vinca Institute @ Joanne Beebe-Wang BNL • Monte Carlo code SRNA-2KG originally developed by R. D. Ilic [Inst. of Nucl. Science Beograd, Yugoslavia, 2002] for proton transport, radiotherapy, and dosimetry. • Modified at BNL to include the production of positron emitter nuclei. • Proton energy range 0.1-250 MeV with pre-specified spectra are transported in a 3D geometry through material zones confined by planes and second order surfaces. • Can treat proton transport in 279 different kinds of materials including elements of Z=198 and 181 compounds and mixtures. • Use multiple scattering theory and on a model for compound nucleus decay after proton absorption in non-elastic nuclear interactions. • For each energy range, an average energy loss is calculated with a fluctuation from Vavilov’s distribution and with Schulek’s correction. The deflection angle of protons is sampled from Moliere’s distribution. • Benchmarked with GEANT-3 and PETRA. A very good agreement was reached. September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 7 Energy deposition of the 169 MeV protons MeV-cm2/g Adsorbed energy in Within slices of Ds=1 cm @ 12 cm @ 11 cm @ 10 cm @ 9 cm @12 cm @ 8 cm @ 7 cm @ 6 cm September 4, 2008 @ 5 cm @ 3 cm @ 2 cm FFAG08 Manchester Workshop – Dejan Trbojevic @a 1 cm depth 8 Vertical Profiles September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 9 Experimental results from: NSRL Laboratory at Brookhaven National Lab - Adam Rusek Ion: C6+ Peak position: 15.95 cm in high density polyethylene (r=0.97 gr/cm3) Kinetic Energy: 292.7 MeV/n LET(in water): 12.9 KeV/mm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 10 Experimental results from: NSRL Laboratory at Brookhaven National Lab - Adam Rusek Ion: H+ Peak position: 37.1 cm in high density polyethylene (r=0.97 gr/cm3) Kinetic Energy: 250.0 MeV/n LET(in water): 0.392 KeV/mm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 11 Spot scanning technique – at PSI, Heidelberg, … Problems with straggling and multiple Coulomb scattering require careful planning to achieve 1% accuracy in accumulated dose Courtesy of Stephen G. Peggs S. Peggs, "Fundamental Limits to Stereotactic Proton Therapy", IEEE TRANSACTIONS ON NUCLEAR SCIENCE, VOL. 51, NO. 3, JUNE 2004, 677 D. C. Williams, "The most likely path of an energetic charged particle through a uniform medium", Phys. Med. Biol. 49 (2004) 2899–2911 September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 12 Straggling and multiple Coulomb scattering Courtesy of Stephen G. Peggs Mult. Coulomb s MS ~ 6.5 mm Straggling s MS ~7.6 mm The total beam size quadrature of the multiple scattering beam size + optical beam size September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 13 Skin depth and required number of voxels Form factor f=1 for a perfect circle D-entire depth of distance total number of voxels require number of pixels in each energy layer September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 14 Skin Depth and required number of voxels September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 15 Spot scanning preparation-longitudinal Courtesy of Stephen G. Peggs Varying the beam size during therapy at different energies and transverse positions. q=32 mrad= tan-1(10 cm/3.2 m) Adjusting btwiss Beam direction September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 16 “Parallel” and 30-40 mrad angle scanning sT Tumor sOPT September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 17 Transverse beam sizes Normalized emittance e @ 0.5 p mm, kinetic energy Ek=200 MeV sOPT= [(btwiss *e)/(6p bg)] g=1.138272/0.938272029=1.21316 bg=0.6868 btwiss(m) sOPT(mm) sMS(mm) sT(mm) qspread(mrad) 0.45 0.23 6.5 6.504 12.06 1 0.348 6.5 6.509 11.84 10 1.101 6.5 6.59 10.73 100 3.483 6.5 7.37 7.475 sT qspread sOPT September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 18 Planning carefully the scan: find the right step size D (start at the end ~10 cm) #2 Central position #1 D~3.14 mm q2~30.3 mrad ~26 cm Scanner magnet: lsc=0.2m Bscanner-max =(q*Br)/lsc Ek=250 MeV Brmax =2.432 Tm Bscanner-max = 0.38 T q2=(0.10-D)/3.2m 12 mrad Qmax~32 mrad 10 -D cm ~ 9.37 cm ~3.2 m Towards the scanner September 4, 2008 ~10 cm qspread =12 mrad D FFAG08 Manchester Workshop – Dejan Trbojevic 19 Example of the non-scaling FFAG carbon gantry-cell September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 20 Proton Gantry with triplet and scanning magnets (it could be built with small permanent magnets F=2 cm) magnified +-10 cm Magnet dimensions, magnetic fields and gradients: L_BD = 25 cm, GD =-33.7 T/m, Bmax= 1.5 T + 33.7 T/m*0.012 mm = 1.9 T L_BF = 30 cm, GF =+35.5T/m, Bmax=-0.25 T -+ 35.5 m*0.028 mm = 1.2 T September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 21 Tracking of protons @ fixed magnetic fields from 90 –250 MeV September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 22 Towards smaller size-proton gantry with superconducting magnets – height ~ 6 m September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 23 Proton gantry with superconducting magnets September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 24 Smaller non-scaling FFAG proton gantry – height 4.7 m September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 25 Smaller non-scaling FFAG proton gantry tracking protons with energies of 79-250 MeV @ fixed magnetic field September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 26 Adjustment of the height with different number of cells September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 27 PSI solution with the non-scaling FFAG September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 28 Carbon gantry design September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 29 September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 30 Lattice functions L= 22 cm Very strong focusing: b x,y~1-2 m Dmax~8.8 cm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 31 Simulation of the particle transport through the gantry -5 mm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic + 5mm 32 Possible continuous coil magnet design for the non-scaling FFAG gantry September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 33 Magnets are available September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 34 Combined Function magnet for the Carbon Gantry September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 35 Summary • Isocentric gantries are necessary in proton/carbon facilities but presently made of too large and heavy magnets. • Spot scanning is very essential for therapy. We presented a real possibility of scanning at the end of the gantry. • A new solution for the isocentric gantry design present reduction in the gantry size and weight comes from the small superconducting magnets – already available. • The weight of 130 tons in the carbon isocentric gantry is reduced to 1.5 tons. • A follow up detail study of the spot scanning from the end of the gantry will be presented soon. September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 36 Experimental results from: NSRL Laboratory at Brookhaven National Lab - Adam Rusek Ion: H+ Peak position: 26.1 cm in high density polyethylene (r=0.97 gr/cm3) Kinetic Energy: 205.0 MeV/n LET(in water): 0.4457 KeV/mm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 37 Experimental results from: NSRL Laboratory at Brookhaven National Lab - Adam Rusek Ion: C6+ Peak position: 8.375 cm in high density polyethylene (r=0.97 gr/cm3) Kinetic Energy: 200.2 MeV/n LET(in water): 16.23 KeV/mm September 4, 2008 FFAG08 Manchester Workshop – Dejan Trbojevic 38