Unit 5 DNA to Protein Lab Stn #1 LT1a Use the Venn diagram to organize the information to show the correct relationship. DNA one gene one genome Please do not move the question to a different lab station. one chromosome _______ _______ _______ _______ nucleotides gene chromosome genome DNA Mrs. Loyd cschmittloyd@waukeeschools.org Page 1 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein LT1 Genetics & DNA Lab Stn #2 VOCABULARY: gene, chromosome, DNA, allele Create a Vocabulary Cartoon for the four terms listed above. See below why this is a great study tool to use when learning vocabulary! Please do not move the question to a different lab station. Use the following format when creating your FOUR cartoons: 1. Write word in a upper corner 2. Define word 3. Create a “Link Word(s),” which is a rhyming work or phase 4. Draw a picture/cartoon with combines the vocabulary word and link word 5. Write a caption to the picture/cartoon with the vocabulary word and link word 6. Check out examples below 7. Get creative! Lab Stn #3 Unit 5 DNA to Protein Unit 5 DNA to Protein Mrs. Loyd cschmittloyd@waukeeschools.org Page 2 of 14 Please3/14/16 do not www.loydbiology.weebly.com move the question to a different lab station. LT1b Explain the two functions of DNA. DNA has two functions. 1. It is the molecule of heredity, meaning, it is the substance that is passed on from one generation to the next. 2. It controls the cell by determining which enzymes are made or not made. Mrs. Loyd cschmittloyd@waukeeschools.org Page 3 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein Lab Stn #4 LT2: Vocabulary: Use the flashcards to practice the vocabulary for this learning target. Vocabulary: double helix, nucleotide, deoxyribose, phosphate group, nitrogen base, thymine, cytosine, guanine, adenine, purine, pyrimidine Please do not move the question to a different lab station. Cut these out and fold to make flashcards. The shape of a DNA molecule. Double Helix Nucleotide The building blocks of nucleic acids consisting of a pentose sugar, a phosphate group and a nitrogen base. Deoxyribose sugar The pentose sugar in DNA. It has NO oxygen at carbon #2. Phosphate Group [PO4]-3 A polyatomic ion that is part of each nucleotide in DNA and RNA. It alternates with pentose sugars to make the backbone of the molecule. Nitrogen Base Carbon rings containing nitrogen. Mrs. Loyd cschmittloyd@waukeeschools.org Page 4 of 14 3/14/16 www.loydbiology.weebly.com thymine A single-ring (pyrimidine) nitrogen base that pairs with adenine in DNA. adenine A double-ring (purine) nitrogen base that pairs with thymine in DNA uracil in RNA. cytosine A single-ring (pyrimidine) nitrogen base that pairs with guanine in both DNA and RNA. guanine A double-ring (purine) nitrogen base that pairs with cytosine in both DNA and RNA. purine A double-ringed nitrogen base. It must pair with a pyrimidine. pyrimidine A single-ring nitrogen base. It must pair with a purine. Mrs. Loyd cschmittloyd@waukeeschools.org Page 5 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein Lab Stn #5 LT2a Please do not move the question to a different lab station. Use the parts to construct and then describe the structure of a DNA nucleotide. Description: A DNA nucleotide is made up of three parts: a phosphate group, a deoxyribose sugar and one of four nitrogen bases: C: cytosine, G: guanine, A: adenine or T: thymine. Cut out the pieces to construct a DNA nucleotide. Mrs. Loyd cschmittloyd@waukeeschools.org Page 6 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein LT2b Lab Stn #8 Describe how DNA nucleotides are connected together to make a DNA molecule. Explain why DNA nucleotides have complementary partners. Please do not move the question to a different lab station. Activity: Discovering the Structure of DNA Mrs. Loyd cschmittloyd@waukeeschools.org Page 7 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein Lab Stn #9 LT2c Use the parts to construct and then describe the structure of a RNA nucleotide. Please do not move the question to a different lab station. An RNA nucleotide is made up of three parts: a phosphate group, a ribose sugar and one of four nitrogen bases: C: cytosine, G: guanine, A: adenine or U: uracil. Mrs. Loyd cschmittloyd@waukeeschools.org Page 8 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein LT3a Lab Stn #10 Organize the images to show the relationship between the following as they pertain to DNA replication. Please do not move the question to a different lab station. Your organization should correctly represent this statement. DNA replication makes exact copies of DNA. This happens during the S phase of the cell cycle in preparation for mitosis and meiosis. It is important to make exact copies because the purpose for DNA replication is to get ready to make new, identical cells by mitosis. Mitosis is for the purposes of growth, maintenance, repair and asexual reproduction. Mrs. Loyd cschmittloyd@waukeeschools.org Page 9 of 14 3/14/16 www.loydbiology.weebly.com Lab Stn #11 Unit 5 DNA to Protein LT3b Explain the importance of hydrogen bonds to the replication of DNA during the S phase of the cell cycle. Please do not move the question to a different lab station. The DNA double helix has two strands held together by H-bonds. These bonds are very weak but multiple weak bonds are strong. Each H-bond can be broken easily using ATP and enzymes. This allows for a mechanism to copy each strand of DNA into two new molecules. This is called semi-conservative replication because each new DNA is half old and half new. Mrs. Loyd cschmittloyd@waukeeschools.org Page 10 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein LT3c Order the images of each stage of DNA replication correctly and then identify what is happening in each. Lab Stn #11 Please do not move the question to a different lab station. Mrs. Loyd cschmittloyd@waukeeschools.org Page 11 of 14 3/14/16 www.loydbiology.weebly.com Unit 5 DNA to Protein LT3 Vocabulary: replication fork, DNA polymerase, base-pairing rules, DNA helicase, DNA Lab Stn #11 replication Use the flashcards to practice the vocabulary for this learning target. Please do not move the question to a different lab station. Cut these out and fold to make flashcards. Replication Fork DNA Polymerase The enzyme that synthesizes new strands of DNA by adding complementary nucleotides to the template strand of DNA. [Purine / Pyrimidine] Base-Pairing Rules Guanine - Cytosine Adenine - Thymine Mrs. Loyd cschmittloyd@waukeeschools.org Page 12 of 14 3/14/16 www.loydbiology.weebly.com DNA Helicase The enzyme that functions to unwind the DNA double helix so that replication or transcription can occur. DNA Replication Before a cell divides, it copies its DNA so both descendant cells will inherit a full complement of chromosomes. Replication of each DNA molecule produces two duplicates. Mrs. Loyd cschmittloyd@waukeeschools.org Page 13 of 14 3/14/16 www.loydbiology.weebly.com Cutouts LT2c LT3a LT3c Mrs. Loyd cschmittloyd@waukeeschools.org Page 14 of 14 3/14/16 www.loydbiology.weebly.com