Rx Communications Group, LLC Capabilities Overview 2000 – 2015: Providing award-winning communications counsel to life sciences and health care companies ABOUT Rx COMMUNICATIONS Specialists in the life science and health care industries Partner-driven -- Senior level counsel on EVERY account Navigate clients through up and down market cycles, various political health care agendas and technology trends ABOUT Rx COMMUNICATIONS Experience with private and public companies – domestic and international Focused on what we do best: Investor Relations and Financial/Science Media Relations Strong Wall Street and media contacts Headquartered in New York City; partnered with Consilium Strategic Communications in London PRIVATE COMPANIES Services for Private Companies WHY EMBARK ON AN IR/PR PROGRAM AS A PRIVATE COMPANY? Lay the groundwork for future financings and eventual IPO Assist with partnering activities by building corporate awareness Build awareness of disease indications to generate product interest Align company with reputable bankers Become accustomed to working within disclosure rules i.e., Reg. FD PROVIDING VALUE TO PRIVATE COMPANIES Develop key messages positioned for analysts and investors Develop collateral materials to tell story integrating key messages Target and facilitate introductions to venture capitalists and institutional investors Target and advise on corporate finance team Target and facilitate introductions to sellside analysts PROVIDING VALUE TO PRIVATE COMPANIES Build presence on the web Review upcoming newsworthy events and develop story ideas for the media Cultivate reporter interest Introduce to conference circuit Strategically position company news to optimize impact Develop company disclosure policy ACTIVITIES SURROUNDING IPO Assist in the selection of banking team – beginning of quiet period Press release announcing registration for offering Develop roadshow presentation Supplement banker’s list of target institutions Presentation training ACTIVITIES SURROUNDING IPO “Teach-ins” at banks Roadshow Press release announcing completion of IPO Create disclosure policy Quiet period compliance PUBLIC COMPANIES Services for Public Companies AFTER-MARKET SUPPORT Need for continual dialogue with shareholders Ongoing targeting of investors for future financings Increase analyst coverage beyond banking support Fulfill disclosure requirements Crisis communications Strategic media outreach GETTING STARTED: FIRST STEPS Strategy session in order to immerse ourselves in corporate story Define key message points Understand perceptions existent in the marketplace Create targeted list of sell-side analysts, venture capitalists and fund managers GETTING STARTED: FIRST STEPS Review collateral materials Create VIP blast e-mail/fax lists Develop media lists Design action plan Rx COMMUNICATIONS CAPABILITIES Strategic Counsel Roadshows Analyst Contact Investor Targeting Investment and Industry Conferences Follow-up and Analysis to Key Events Press Release Writing News Conferences/Press Briefings Video/Radio News Releases Fact Sheets Annual Reports Rx COMMUNICATIONS CAPABILITIES Crisis Communications Mergers and Acquisitions Positioning Strategy Perception Audits Conference Calls Presentation Training Placement Strategy Financial, Trade and Local Media Contacts Slide Presentations Web Site Development THE Rx TEAM Melody A. Carey, President Founded Rx Communications in 2000 Head of Corporate Communications and Spokesperson, Schein Pharmaceutical, Inc. Director of Investor Relations, The Multicare Companies, Inc. Executive, Noonan/Russo Communications Former health care/life sciences investment banker, Kidder, Peabody & Co. THE Rx TEAM Rhonda Chiger, Senior Advisor Founded Rx Communications in 2000 Senior Managing Director, Global Consulting Practice, Thomson Financial Managed Life Sciences departments for Noonan/Russo and Dewe Rogerson Established London office for health care investor relations firm Manager, Investor Relations, American Stock Exchange THE Rx TEAM Paula B. Schwartz, Senior Vice President Twelve years with Rx Communications Partner, FRB/Weber Shandwick, oldest and largest Investor Relations firm in the U.S. Vice President, ECOM Consultants, Inc., an investor relations firm Vice President/Director of Investor Relations Programs, KCS&A Public Relations, a public relations and investor relations consultancy THE Rx TEAM Steve Silver, Senior Vice President Joined Rx Communications in April 2015 More than15 years of professional experience as a Wall Street analyst focused on healthcare and an investor relations specialist Senior Industry Equity Analyst at S&P Capital IQ, covering Biotechnology and Healthcare Facilities Senior Investor Relations Manager, Anne McBride Company and Global Consulting Group (both now part of Grayling) THE Rx TEAM Stacey Jurchison, Investor Relations Specialist 20 years specialized experience as dedicated in-house IR life sciences practitioner Director of Investor Relations for PharmAthene, Inc. and Guilford Pharmaceuticals, Inc. Developed and implemented IR programs that included M&A activities as well as corporate litigation. THE Rx TEAM Jules Abraham, Senior Media Consultant Nearly 20 years of healthcare public relations experience representing large and specialty pharmaceuticals, biotechnology, medical devices, clinical diagnostics, healthcare IT, healthcare services Supported market conditioning, clinical trial recruitment, financial and milestone communications, corporate communications, product launches and post-market publicity. Public Relations Executive, Feintuch Communications, Lippert/Heilshorn and Manning Salvage & Lee. Rx COMMUNICATIONS CURRENT CLIENT LIST Admedus Ltd. (ASX – Australian Market: AHZ) Alexandria Real Estate Equities, Inc. (NYSE: ARE) Bellerophon Therapeutics LLC (Nasdaq: BLPH) Bio-Path Holdings, Inc. (Nasdaq: BPTH) Cell Medica Ltd. (Private) Ceramedix, Inc. (Private) CollPlant Holdings Ltd. (TASE: CLPT) CytoPherx, Inc. (Private) Ion Beam Applications, S.A. or IBA (Euronext Brussels: IBAB) MAXIMUS, Inc. (NYSE: MMS) MDxHealth, S.A. (Euronext: MDXH) Midatech Pharma Plc (Nasdaq: MTP/AIM: MTPH) Nanotherapeutics, Inc. (Private) Rx COMMUNICATIONS CURRENT CLIENT LIST Ophthotech Corporation (Nasdaq: OPHT) OSE Pharma SA (OSE.PA) Orexo AB (Nasdaq OMX: ORX & US OTXOX: ORXOY) Oxford BioMedica Plc (LSE: OXB) PharmAthene, Inc. (NYSE MKT: PIP) Semler Scientific, Inc. (Nasdaq: SMLR) Sequana Medical AG (Private) Therabron Therapeutics, Inc. (Private) Vigilant Biosciences, Inc. (Private) VistaGen Therapeutics, Inc. (OTCQB: VSTA) Zealand Pharma A/S (Nasdaq: OMX Copenhagen: ZEAL) OURx SUCCESSES Helped to grow Alexion Pharmaceuticals’ institutional shareholder base from 30% in 1996 to approximately 95% today. Launched not-for-profit Immune Tolerance Institute resulting in broad coverage in the U.S. including CBS Radio Network, San Francisco Business Times and Drug Discovery News. Garnered coverage for Catalyst Pharmaceutical Partners’ compound for cocaine addiction. Placements included cover stories in Newsweek, Scientific American Mind and NeuroInvestment. OURx SUCCESSES Designed and implemented assertive investor outreach program for PDI which doubled trading volume and tripled its stock price within nine months. Arranged feature coverage focused on Hodgkins and non-Hodgkins lymphoma for MethylGene with Genetic Engineering News, Pink Sheet, BioCentury and Pharmawire Implemented aggressive IR program for PharmAthene, Inc. which enabled the company to obtain coverage from two new sell-side analysts, garner investments from four new institutional funds and increase trading volume by three-fold within nine months. OURx SUCCESSES Generated feature articles with Dow Jones Newswire, BioWorld Today, FierceBiotech for the TetraLogic Pharmaceuticals Series C financing. Devised communications campaign to increase visibility of Amorcyte’s enriched bone marrow stem cell therapy by maximizing clinical data presented at American College of Cardiology (ACC) conference. Leveraged key opinion leaders who presented Amorcyte’s data to gain media coverage, surpassing competitors with later stage clinical data and larger operating budgets. News coverage included: Reuters, CBS Radio Network, Start-Up Magazine & Pharmawire. OURx SUCCESSES Generated news coverage with Dow Jones Newswire, Wall Street Journal.com, Drug Discovery & Development for launch of Neovacs autoimmune disease therapeutics. Developed compelling key messages and arranged media interviews surrounding ZIOPHARM Oncology sarcoma clinical trials resulting in news coverage from Bloomberg Television, Reuters Newswire, BusinessWeek, Associated Press, Wall Street Journal and Forbes. Within nine months, re-positioned MAXIMUS from a business processing company to a health care services company. Garnered health care sell-side research coverage from Bank of America and Citigroup Global Markets. OURx SUCCESSES We are pleased to announce that Rx Communications has been selected by PR Week as a finalist for Rx Communications was named Best Small PR Agency by League of American Communications Professionals Boutique PR Agency of the Year Rx Communications Group was honored with the Stevie Award for Best Investor Relations Program for work on behalf of specialty pharmaceutical company, NexMed, Inc. OURx SUCCESSES Rx Communications was honored with the SABRE Awards Certificate of Excellence for Building a North American Investor Base for client Syngenta AG. We are also pleased to share that our work for ImpactRx has won an Honorable Mention Award in LACP’s (League of American Communications Professionals) Publicity Campaign Competition. Rx Communications received an honorable Mention Award from PR News, as part of the PR News Platinum PR Awards. The award was issued in the Financial/Investor Relations category, for the company's work on behalf of Genaissance Pharmaceuticals, Inc. WHY Rx COMMUNICATIONS? Specialist industry knowledge and expertise Personal attention from Rx partners Decades of experience in strategic counsel and implementation of financial public relations programs Unique niche in working with private companies Well versed in IPOs, secondary offerings, PIPEs, venture rounds and mergers and acquisitions “The Street” knows and trusts us For Additional Information: Rx Communications Group, LLC 555 Madison Avenue 5th Floor New York, NY 10022 (917) 322-2568 www.RxIR.com