Epithelial Tissue Key Terms Histology: – the study of tissues. Tissues: – Simply groups of similar cells that work together performing the same task – Greatest form of teamwork in the body Where are tissues found? With few exceptions, organs are composed of four basic tissue types: – Epithelial Tissue – Connective Tissue – Muscular Tissue – Nervous Tissue Why Study Histology? Knowing the difference between normal and abnormal tissue is the first step in diagnosis and treatment of patients. Skin, our largest organ * made of all four tissue types Epithelial Tissue Makes up 3% of your body weight They don’t move They don’t send messages Their cells are all touching one another Of all tissues, they are the most widely varied in structure and function Locations of Epithelial Tissues Covers the body (epidermis) Found on the inside of hollow organs and the outside of all organs Found above a connective tissue layer (epi = above) Lines the cavities, tubes, ducts, and blood vessels inside the body Epithelial Anatomy Apical surface – upper surface that is free or exposed to the “exterior” Basal surface – attached surface (below) Microvilli – small fingerlike extensions that increase the surface area allowing for more work to be done Functions of Epithelial Tissue – Protects from physical & chemical injury – Protects against microbial infection – Contains nerve endings which respond to stimuli – Filters, secretes & reabsorbs materials – Secretes fluids to lubricate joints Three Basic Shapes Squamous – like scales, or pancakes (“being squashed like a pancake”) Cuboidal – looks like cubes Columnar – longer and look like columns Cell Organization Simple – single layer of cells; typically found where absorption and filtration occur or a single layer of epithelial is needed simple squamous simple cuboidal simple columnar Stratified – layers of cells; common in areas where protection is needed like the skin stratified squamous stratified cuboidal stratified columnar Two Types of Stratified Columnar Ciliated cilia Unciliated No cilia Squamous Epithelium Simple – one cell thick Forms solid layer of cells which line blood vessels, body cavities and covers organs in body cavities Stratified – multiple layers Forms epidermis Cuboidal Epithelium Cuboid Cells Simple – one cell thick Duct Roughly cube shaped Cuboid Cells Duct Line ducts in kidneys where re-absorption and secretion activities take place. Columnar Epithelium Simple – one cell thick Column shaped (long and narrow) Lines digestive tract where re-absorption & secretion occurs. Confusing Epithelial Tissue Transitional Epithelium – stratified tissue that can’t make up its mind as to whether it is squamous or cuboidal Shape of cells depends upon the amount of stretching (ex: bladder) Confusing Epithelial Tissue Continued… “Pseudostratified Columnar Epithelium” Looks like it has more than one layer because of the position of the nucleus Nuclei are positioned at differing levels Cells narrow in the area without the nucleus Epithelial Tissue in Review… Types of Epithelial Membranes Mucous or mucosa– lining of tubes; moistens and protects from enzymes (stomach, trachea, and vagina) Serous or serosa – outside of organs; lubricates (all thoracic, abdominal and pelvic organs) Cutaneous or skin – body surface; protection Synovial – synovial joints; lines and protects synovial cavities (elbow, knee, hip, etc.)