HISTOLOGY: Study of Tissues Four Types? Two components of tissue? 4 Types • • • • Epithelial tissue Connective tissue Muscular tissue Nervous tissue 2 Components of Tissue • Cells • Extracellular matrix Focus: Epithelium LOCATION OF EPITHELIUM: • • • • • Lining of body cavities Lining of digestive tract Lining of heart and blood vessels Lining of gland ducts Skin FUNCTION OF EPITHELIUM • Protection • Absorption – one side of the tissue is always in contact w/ external opening (maintains homeostasis) • Secretions – hormones, mucus, enzymes How epithelial tissues are classified: SHAPE: • Squamous – thin, think “squished” • Cuboidal – cubed shape • Columnar – rectangular think “column” LAYERS: • Simple = single layer • Stratified = more than one layer Types of epithelium • • • • Simple squamous Simple cuboidal Simple columnar Stratified cuboidal “special” types of epithelium • Pseudostratified cuboidal or columnar – “false layers”, looks like there is more than one layer b/c nucleus alignment in cells • Transitional epithelium – tissues that adjusts to various tensions (think bladder) Anat/physiology October 9, 2006 1. Turn in epithelium packet w/ drawings attached 2. POP QUIZ on identifying types of Epithelial tissue 3. Test on Ch 5 – epithelium and connective tissue on Friday!! Pop quiz #1 Pop quiz #2 Pop quiz #3 Pop quiz #4 Pop quiz #5 Pop quiz #6 Pop quiz #7 Pop quiz #8 Pop quiz #9 Pop quiz #10 Connective Tissue 3 TYPES •Connective tissue proper •Fluid connective tissue •Supporting connective tissue Connective tissue proper • Many types of cells in a syrupy ground substance • Ex of where found = tendons, surrounding organs, ligaments, surrounds respiratory passageway • Two types of connective tissue – loose connective – dense connective Connective tissue proper: CELLS • Fibroblasts (slender and star-shaped cells) Connective tissue proper: CELLS • Macrophages Connective tissue proper: CELLS • Adipose cells (stores fat) Connective tissue proper: CELLS • Mast Cells Connective tissue proper: CELLS • Plasma Cells Connective tissue proper: FIBERS • Collagen – Found in tendons and ligaments Connective tissue proper: FIBERS • Elastic Fibers – Rare but important – Found between vertebrae and aorta Connective tissue proper: FIBERS • Reticular Fibers – holds blood vessels to surface of organs Marfan Syndrome • Genetic disorder that effects the production of connective tissue – Effects just about every system in the body – Especially dangerous for blood vessels: collapse and/or bursting of aorta Connective tissue proper: GROUND SUBSTANCE • Loose (aka areolar) • Dense • Adipose Connective tissue proper: GROUND SUBSTANCE • Loose connective (areolar) – “packing material” – Fills spaces between organs, supports epithelium – Forms a layer that separates skin from deeper structures like muscles – Highly vascularized, shots given in this tissue for quick transport of drugs Connective tissue proper: GROUND SUBSTANCE • Adipose – Cushioning and energy storage – Found under skin of groin, buttocks, breasts and abdomen – Also fills bony sockets behind eyes – dominant connective tissue of thoracic and abdominopelvic cavities Connective tissue proper: GROUND SUBSTANCE • Dense Connective – Tightly packed collagen fibers make this tissue really strong – Found in tendons, ligaments, surrounding muscles, and surrounds blood vessels and respiratory passageways Fluid Connective Tissue • Blood and Lymph Supporting Connective Tissue • Cartilage – ground substance surrounding chondrocytes (cartilage cells) called matrix, matrix is firm gel • Bone – matrix is rigid because of calcification and contains osteocytes (bone cells) (more next chapter) Supporting Connective Tissue: CARTILAGE • Hyaline – found between ribs and the sternum, along passageway of respiratory tract, opposing surfaces of bones with many joints (elbow and knee) • Elastic – outer ear, epiglottis and tip of nose • Fibrocartilage – between vertebrae, pubic bones of pelvis, some joints and tendons Cartilage and Knee Injuries • Cartilages are avascular so they heal poorly • New research in growing and replacing cartilage has showed promise in dog studies Fig. 5.19b Fig. 5.19c Last Two Types • • • • Epithelial Tissue Connective Muscle Nervous Muscle • Smooth • Skeletal (striated) • Cardiac Smooth • Lines organs such as those of the digestive tract Fig. 5.22b Skeletal • Voluntary control – able to contract and create movement • Multi-nucleated and visible striations Fig. 5.21b Nervous tissue • Makes up tissue of Central and Periferal Nervous systems Fig. 5.24b Skeletal System Instructions 1 2 3 4 5 6 7 8 9 10 Team Score 1 3 2 6 1. The outer covering of the diaphysis of the long bone, made from fibrous tissue is called the EPIPHYSIS DIAPHYSIS PERIOSTEUM ARTICULAR CARTILAGE Who is the strongest link? PERIOSTEUM Periosteum is the connective tissue that covers long bones and is thicker in children than adults. Next Question 1. Compact bone is made up of _______ cemented together. Osteons Osteocytes Perforating canals Who is the strongest link? Trabiculae OSTEONS Next Question The cells that tear down and remodel bone are the ____________. Marophages Osteocytes Osteoblasts Who is the strongest link? Osteoclasts OSTEOCLASTS Osteoclasts release a strong acid that breaks down bone. Next Question Inside the epiphyses of each long bone, mostly _______ can be found. Yellow Marrow Cartilage Compact Spongy bone bone Who is the strongest link? Spongy Bone Next Question 1. Which bones do not belong to the axial skeleton? Hip Skull Ribs Bone Who is the strongest link? Vertebrae HIP BONES Only the coccyx bone of pelvic region belongs with the axial skeleton. Next Question 1. How many bones are there total in the adult human body? 450 280 206 Who is the strongest link? 180 206 Children have approx 450 cartilaginous bones that develop and fuse into 206 adult bones. Next Question 1. The medullary cavity in the diaphysis of an adult bone would contain _______. Organic Blood Spongy Compact salts vessels bone bone Who is the strongest link? BLOOD VESSELS Explanation of Answer Goes Here Next Question 1. The part of the bone that articular cartilage covers directly is the ________. Endosteum Periosteum Diaphysis Who is the strongest link? Epiphysis EPIPHYSIS Next Question The junction between the diaphysis and epiphysis in growing bone is called the Epiphyseal Endosteum Periosteum plate Articular plate Who is the strongest link? EPIPHYSEAL PLATE Contains dividing cells that cause bone elongation Next Question 1. The broad, flat bones of the skull are ____________. Cartilaginous Endochondral Spongy Who is the strongest link? Intramembranous INTRAMEMBRANOUS Next Question How to play The Strongest Link 1. Divide the group up into two teams. Assign one group to be Team 1, the other will be Team 2. Have each team choose a spokesperson. 2. Begin the PowerPoint and introduce the characters. 3. Have the spokesperson from one team choose a question. 4. Click on that number. Read the question and allow the spokesperson to confer with teammates to come up with an answer. Have them state the answer orally, then click on the arrow button. 5. Read the answer displayed on the next slide. Click on the button to move back to the board. 6. If the answer given was correct, type the correct number of points in the score box. 7. Continue to play until all questions have been answered. The team with the most points wins. Let’s Play! MUSCLES! Instructions 1 2 3 4 5 6 7 8 9 10 Team Score 1 5 2 3 1. Most of the bones of the body are ____________. Spongy bone Intra membranous Endochondral Who is the strongest link? Cartilaginous ENDOCHONDRAL Explanation of the Answer Goes Here Next Question 1. Which of the following is an example of an irregular bone? Vertebrae Rib Humerus Who is the strongest link? Clavicle VERTEBRAE Next Question 1. Which bone cell works to rebuild bone tissue? Osteons Osteocytes Osteoclasts Who is the strongest link? Osteoblasts Osteoblasts Osteoblasts lay down inorganic salts which help to form compact bone. Next Question 1. In order to create movement, bones function as _______. Fulcrums Pulleys Machines Who is the strongest link? Levers LEVERS Next Question 1. Which component of the bone is responsible for creating blood cells? Red Yellow Spongy Compact Marrow Marrow Bone Bone Who is the strongest link? RED MARROW Red marrow contains premature blood cells that can be stimulated to mature when more blood cells are needed. Next Question A small bundle of muscle fibers Fascia Myofibril Fascicle Who is the strongest link? Epimysium Fascicle Next Question Network of connective tissue that extends throughout the muscular system Endomysium Epimysium Perimysium Who is the strongest link? Sarcolemma EPIMYSIUM Connective tissue that covers the muscle and is continuous with fascia Next Question Layer of connective tissue that surrounds a skeletal muscle Perimysium Endomysium Epimysium Who is the strongest link? Fascia FASCIA Next Question Layer of connective tissue that separates a muscle into small bundles called fascicles Perimysium Endomysium Epimysium Who is the strongest link? Sarcolemma PERIMYSIUM Next Question Cellular organelle in muscle fiber corresponding to the endoplasmic reticulum Sarcoplasm Sarcolemma Sarcomere Who is the strongest link? Sarcoplasmic Reticulum SARCOPLASMIC RETICULUM Next Question How to play The Strongest Link 1. Divide the group up into two teams. Assign one group to be Team 1, the other will be Team 2. Have each team choose a spokesperson. 2. Begin the PowerPoint and introduce the characters. 3. Have the spokesperson from one team choose a question. 4. Click on that number. Read the question and allow the spokesperson to confer with teammates to come up with an answer. Have them state the answer orally, then click on the arrow button. 5. Read the answer displayed on the next slide. Click on the button to move back to the board. 6. If the answer given was correct, type the correct number of points in the score box. 7. Continue to play until all questions have been answered. The team with the most points wins. Let’s Play!