2_Factors in the Spread of Disease

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FACTORS IN THE SPREAD

OF DISEASE

Spread of Diseases

There have been several diseases that have spread across the world killing many

In the middle ages it was the Bubonic or

Black Plague

In 1981 it was HIV

Epidemiology

An area of investigation that deals with factors that influence the frequency and distribution of diseases

Find ways to control and prevent the outbreak of disease

Look for the source of transmission

Reporting of the control of the disease

Patterns of Disease Occurrence

Incidence or Prevalence

The number of new cases seen in a specific time period

Morbidity Rate

 The number of new cases per 10,000 in the population per year

Mortality Rate

 Refers to the number of individuals that died as a result of a specific disease in a specific time period

Endemic, Epidemic, Pandemic and

Sporadic Disease Patterns

Endemic Disease

A disease that is constantly present in the population of a particular geographic area, but involves relative few individuals

 Severity of the disease is low

Does not present as a major public health problem

Tuberculosis, mumps, the STD chancroid and gonorrhea

Endemic, Epidemic, Pandemic and

Sporadic Disease Patterns

Epidemic

An unusual occurrence of a disease involving large segments of a population for a limited period of time

An endemic disease can develop into an epidemic if a harmful form of the pathogen appears

Influenza and measles are good examples

 Genital Herpes and Genital Warps are in epidemic proportions

Endemic, Epidemic, Pandemic and

Sporadic Disease Patterns

Pandemic

A series of epidemics affecting several countries, or even major portions of the world

 Influenza of 1918-

1919

HIV and AIDs are following a similar pattern

Endemic, Epidemic, Pandemic and

Sporadic Disease Patterns

Sporadic Diseases

Are uncommon, occur irregularly and affect only a relatively few persons

 Diptheria

 Whooping Cough – although this is on the rise in the US

Transmission Factors include:

Sources and reservoirs of disease agents

Portals by which the agents leave and enter the body

The mechanisms or means of transmission

Factors in the Spread of Infectious

Diseases

Reservoirs of Infection

A host or local environment that supports the survival and multiplication of pathogens is referred to as a reservoir of infection

Living reservoirs include infected humans and other animals

Nonliving reservoirs include air, food, soil, water, eating utensils and toothbrushes

Provides the disease agent a suitable environment to survive for prolonged periods

Factors in the Spread of Infectious

Diseases

Carrier

Individuals who harbor pathogens transmissible to others

Healthy Carrier

A carrier with no apparent ill effects

Incubatory Carrier

The individual who is in an incubating state, undergoing the initial stages of a disease without exhibiting symptoms

Intermittent Carrier

Periodically releases disease agents

Convalescent Carrier

Serves as a source of pathogens during the recovery period

How do Pathogens Get Into and Out of the Body?

Portals of Entry

Pathogens enter the body through a small number or routes

 Skin

 Respiratory system

 Gastrointestinal system

Genitourinary system

 Wounds

 Animal bites

Particular pathogens are generally restricted to a specific portal of entry

Portal of Entry

Infectious Dose

The number of pathogens needed to initiate a disease process

 May be as low of one organism or may need hundreds of thousands

HIV infection requires large doses of disease agent

The pathogen must overcome the hosts defenses in order to enter

If it cannot overcome the defenses the pathogen dies

Portals of Exit

The site at which the organisms leave the body

Pathogens are typically discharged with body fluids and wastes.

Respiratory pathogens exit by

 Coughing

Sneezing

Speaking

STDs such as gonorrhea and HIV discharge through semen and vaginal secretions

Mechanisms of Disease Transmission

Transmission may occur by:

Direct contact with infected person or carrier

Indirect contact with nonliving objects, or food or water contaminated by infected individuals

Inhalation of airborne dust or droplets of saliva, or other body fluids containing pathogens

Injection of body fluids containing disease agents

Insects and related forms carrying pathogens

Contact Transmission

Direct Contact

Refers to the transmission of pathogens from person to person through close personal association

Coughing

Sneezing

Handshaking

Kissing

Sneezing

Indirect Contact

Infectious agents are carried form one individual to another on contaminated, living or nonliving objects

Fomites

Contaminated nonliving objects other than food and water

Hypodermic needle

Toothbrush

Eating utensils

Mechanical Transmission

Transmission where situations involving the physical carrying of pathogens on or within contaminated materials such as food, water or insects

Five F’s

Food

Fingers

 Flies

 Feces

 Fomites

Mechanical Transmission

Vector

Forms of life that transmit disease to humans

Flies

Ticks

Cockroaches

Mosquitoes

Mechanical Vectors

Transmitters that carry infectious agents on their bodies and are not used by the agents for multiplication

Biological Vectors

Serves as reservoirs and are at times required by disease agents for their development

Ticks

Mosquitoes

There are no known STDs transmitted by arthropod vectors

Biological Transmission

A portion of the pathogen’s development occurs in the form of life that serves to transmit the disease agent

Injection of blood

Blood products

Bites of warm-blooded animals

Arthropods

Malaria

Rabies

Hepatitis

HIV

Horizontal and Vertical Transmission

Horizontal Transmission

Transfer of disease agents in the population by air, physical contact, food, water or vectors

Vertical Transmission

Transfer of infectious agents from parent to offspring by means of male and female sex cells or breast milk or during pregnancy

 Syphilis and HIV

General Approaches to the Control of

Contagious Diseases

Isolation and Quarantine

Prevents contact with the general population

 Minimizes the spread of the disease

 Protects infected individual from exposure to other diseases

Elimination of Vectors and Sources of Disease

Agents

Hand washing

Disinfectant

Insecticides

Immunization

Vaccination for the prevention of diseases

Builds resistance to the disease

Large spread controversy today

The signs of certain sexually transmitted diseases

(STDs) such as syphilis and chlamydial infection are not always obvious

A.

B.

True

False

In general, STDs can be acquired through casual contact situations such as shaking hands.

A.

B.

True

False

Diagnostic tests are available for the detection of most STDs.

A.

B.

True

False

Most STDs are treatable if detected early.

A.

B.

True

False

Having an STD such as syphilis, chancroid, or genital wars can increase the possibility of human immunodeficiency (HIV) transmission.

A.

B.

True

False

The proper use of latex condoms during sexually related activities, while not foolproof, is effective in preventing STD transmission.

A.

B.

True

False

An infected mother can transmit certain STDs such as syphilis and HIV infection to her newborn.

A.

B.

True

False

With the exception of hepatitis B virus infection, no immunization (vaccines) are available for any STD.

A.

B.

True

False

The use of oil-based lubricants such as Crisco and

Vaseline can weaken condoms, making them useless as protection against STD transmission

A.

B.

True

False

Sexually transmitted diseases can spread by women as well as men.

A.

B.

True

False

An individual can acquire an STD by donating blood.

A.

B.

True

False

Sexually transmitted diseases such as syphilis and gonorrhea can be spread by kissing.

A.

B.

True

False

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