Agnes Scott College Department of Chemistry (an American Chemical Society approved program) Program in Biochemistry and Molecular Biology (BMB) Why Major in Chemistry or BMB? Career Opportunities Research (industry, biomedical fields) Academic chemist (biomedical, biological) Medical school MD MD/PhD Teaching (MAT) Law school Library science What do our majors do? Sara B. – second year graduate student at Northwestern University DeeDee S. – third year graduate student at Northwestern University Patrice B. – 2003, Ph.D. Purdue University, Dreyfus Fellow, Ga. Instit. Tech. Nina T. – Research Fellowship, CDC Abena F. – Rollin’s School of Public Health Sara S. – CDC Fellowship in Namibia Mary F. – 1st year graduate student at Emory Chemistry Faculty Doug Fantz, Assistant Professor Biochemistry, organic chemistry, first year seminar Lilia Harvey, Associate Professor Organic chemistry, senior seminar Ruth Riter, Assistant Professor Analytical chemistry, introductory chemistry, quantitative analysis, environmental chemistry Leon Venable, Associate Professor Introductory chemistry, bioinorganic chemistry, advanced inorganic chemistry Patrice B., sabbatical replacement for 06-07 Sara Winget, Visiting Professor Physical chemistry, introductory chemistry Courses of Study Regular Chemistry Major ACS (American Chemical Society) Approved Chemistry Major Chemistry Minor Biochemistry & Molecular Biology (interdisciplinary major with biology) non-ACS degree Class Description Hours 101/101L Matter and Rxns 4 102/102L Periodicity 4 201/201L Organic I 4 202/202L Organic II 4 301/301L P. Chem. I 4 302 P. Chem. II 4 311 Quant. Chem. Anal. 4 312 Instrumental 4 342L/343L Phys. and Inst. Meth. 1/1 431/L Variable Mod. Inorg. 4 Any advanced chem. 4 Total Hours 42 Non-Chem Pre/corequisites Chemistry Curriculum Math 118,119,220(R); Physics 110,111 Physics 242,243 (electronics (2 hr each)) ACS certified degree -addition of Biochem. I Minor 2 courses beyond 202 Total hours w/ prereqs 62 ; 66(R) BMB Curriculum Biology Chemistry BIO 191 : Molecular and Cellular Biology CHE 101/101L : Fund. Concepts of Matter and Reactions BIO 192 : Genetics and Developmental Biology CHE 102/102L : Periodicity and Chemical Reactions BIO 316 : Molecular Biology CHE 201/201L : Organic Chemistry I BIO 300 / CHE 300* : Biochemistry I CHE 202/202L : Organic Chemistry II CHE 300 / BIO 300* : Biochemistry I plus one of the following BIO courses: CHE 301 : Physical Chemistry I CHE 342L : Physical and Instrumental Methods of Exp. I CHE 400 : Biochemistry II BIO 301 : Microbiology BIO 309 : Cells and Tissues plus one of the following CHE courses: BIO 315 : Genetics BIO 317: Immunology BIO 318 : Developmental Biology CHE 210 : Bio-inorganic Chemistry CHE 302 : Physical Chemistry II CHE 311 : Quantitative Chemical Analysis * Note: BIO 300 and CHE 300 are cross-listed courses, and either (but not both) can be taken to satisfy the major. ** Note: CHE 301 requires MAT 118 & 119 as well as PHY 110 & 111. Research Requirement Course features Small classes Small labs Labs are taught by Ph.D. chemists Hands-on access to equipment Collaborative research opportunities Research Opportunities Research with chemistry and biology faculty members Interdisciplinary research with faculty from other disciplines Research collaborations (interdisciplinary or strictly chemical) with scientists at other institutions Doug Fantz- Biochemistry Investigation of the Ras pathway using C. elegans as a model organism C. elegans H. sapiens lin-3 EGF let-23 EGFR sem-5 GRB2 let-60 RAS lin-45 RAF mek-2 MAPKK mpk-1 MAPK lin-1 Elk-1 1˚ vulval fates proliferation CH3O Lilia Harvey – Organic Chemistry O Photochemistry of Alpha-(Aryloxy) AcetophenoneO and Derivatives CH3O O O O O O O CH3O O O O O CH3O O O O O Ruth E. Riter – Analytical Chemistry Photoinduced Electron Transfer Across Reverse Micellar Interfaces T. Leon Venable – Inorganic Chemistry (1)Synthesis and Characterization of Ru-B Clusters as Potential Cancer Therapy Agents (2)Synthesis and Characterization of Cu-Amino Acid Complexes Sarah Winget – Physical Chemistry - use of vibrational spectroscopy to design and characterize surface and interface chemistries SEM image from Zhao et al, International Journal of Nanoscience, 1, (2002) 87-97 New Equipment ~ $750,000 worth of new equipment and equipment upgrades Spectroscopy: UV-VIS, FT-IR, Laser, Raman Separatory/analytical: GC, GC/MS, HPLC, CE Structural/analytical: NMR – 400 MHz Probe microscopy: STM/AFM Data acquisition Scanning Tunneling Microscopy STM / Atomic Force Microscopy AFM STM Image of Graphite Molecular Model of Graphite 2.5 Å NMR Nuclear Magnetic Resonance – Same process as used in MRI (Magnetic Resonance Imaging) 400 MHz – Greater sensitivity – Can study proteins – Other resonances C-13, B-11, P-31, etc. Student Affiliates of the American Chemical Society Active student chemistry organization Four-time national award winners for chapter activities Outreach activities Tutoring Chemistry shows & demonstrations Campus open-house activities Questions? Dr. Douglas Fantz SC301W x-5067 dfantz@agnesscott.edu