Introduction
BIO 411
Medical Microbiology

The Prophet’s View of Education
• “You are all in school. Do not waste your time. This is a time of great opportunity that you will never have again as long as you live. Make the most of it right now….
• “…you can’t afford to waste your time.
There is so much to learn. Give it the very best that you have.” – Gordon B. Hinckley

Syllabus
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So what are we going to learn about this semester?
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Syllabus
• What does it take to succeed in Bro. Wray’s class?
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First Assignment – Elder Eyring Article

Medical Microbiology
Chapter 1
Intro. to Medical Microbiology

Intro. to Medical Microbiology
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History of Microbiology
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Anton van Leeuwenhoek (1674)
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Friedrich Henle (1840) – Germ Theory of
Disease
– Robert Koch and Louis Pasteur (late 1800’s)
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Alexander Fleming (1928) - Penicillin

Intro. to Medical Microbiology
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Groups of Microorganisms
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Viruses
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DNA or RNA genome
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Protein coat (capsid)
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Some have a membrane envelope
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Obligate intracellular parasites
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Pathogenesis
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Diseases?

Intro. to Medical Microbiology
– Bacteria
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Prokaryotic organisms
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Peptidoglycan cell wall
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Gram + and Gram –
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Cell shapes and arrangements
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Pathogenesis - toxins
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Diseases?

Intro. to Medical Microbiology
– Fungi
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Eukaryotic
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Yeasts, molds, dimorphic fungi
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Diseases?
– Parasites

Intro. to Medical Microbiology
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Microbial Disease
– Most organisms don’t cause a single disease
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Staphylococcus aureus, meningitis, etc.
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Few microbes are always pathogenic
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Exogenous infections vs. endogenous infections
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Normal Flora