IB Biology Study Guide Topic 1: Cell Biology 1.5 – The origin of cells Essential Idea – There is an unbroken chain of life from the first cells on Earth to all cells in organisms today. 1.6 – Cell Division Essential Idea – Cell division is essential but must be controlled. I. II. III. IV. Terms: cell theory prophase mutagen Pasteur experiment metaphase oncogenes endosymbiotic theory anaphase metastasis prokaryotic cell telophase cyclin eukaryotic cell chromosome cancer mitosis chromatid (sister tumors chromatid) cell cycle centromere interphase (G1, S, G2) HOMEWORK: Reading – TEXT BOOK i. 2.1 Cells, page 12 – 28 ii. 2.5 Cell Division, page 38 – 43 iii. D.1 Origin of Life on Earth, page 421-422 Reading – Slides i. Topic 1.5: http://www.slideshare.net/diverzippy/biok-15-origin-of-cells ii. Topic 1.6: http://www.slideshare.net/diverzippy/bioknowledgy-16-cell-division Understandings The origin of cells Cells can only be formed by division by pre-existing cells. The first cells must have arisen from nonliving material. The origin of eukaryotic cells can be explained by the endosymbiotic theory. Cell Division Mitosis is division of nucleus into two genetically identical daughter cells Chromosomes condense by supercoiling during mitosis. Cytokinesis occurs after mitosis and is different in plant and animal cells. Interphase is very active phase of the cell cycle with many processes occurring in the nucleus and cytoplasm. Cyclins are involved in the control of the cell cycle. Mutagens, oncogenes and metastasis are involved in the development of primary and secondary tumors. Applications & Skills The origin of cells Application: Evidence from Pasteur’s experiments that spontaneous generations of cells and organisms does not now occur on earth Cell Division Application: The correlation between smoking and incidence of cancers. Skill: Identification of phases of mitosis in cells viewed with a microscope or micrograph. Skill: Determination of a mitotic index from a micrograph. (The mitotic index is an important prognostic tool for predicting the response of cancer cells to chemotheraphy). Figures to know KNOW THE VARIOUS STRUCTURES OF DNA Double helix Chromatin . Chromatid Chromosome