TITANIC Launched: 31st May 1911 Passengers Lost: 818 (62%) Total Lost: 1,502 (68%) Crew Lost: 684 (77%) WHY did soooo many die as they awaited rescue in the North Sea? WHY did soooo many die as they awaited rescue in the North Sea? HINT: THE NORTH SEA IS COLD!!!!! Function of Cellular Respiration… harvesting the energy of food for ATP synthesis… so the cells have energy for WHAT if there is NO electronegative oxygen to pull electrons down the chain???? Oxidative phosporylation STOPS! GAAAAK!!!! Glucose CYTOSOL Pyruvate No O2 present Fermentation O2 present Cellular respiration MITOCHONDRION Ethanol or lactate Acetyl CoA Citric acid cycle Fermentation the synthesis of ATP via. glycolysis ONLY in the absence of oxygen QuickTime™ and a decompressor are needed to see this picture. Alcohol fermentation is done by yeast and some kinds of bacteria. QuickTime™ and a decompressor are needed to see this picture. yeast / bacteria. The waste products of this process are ethanol and carbon dioxide (CO2). QuickTime™ and a decompressor are needed to see this picture. yeast / bacteria. The waste products of this process are ethanol and carbon dioxide (CO2). Humans have long taken advantage of this process in making bread, beer, and wine. Alcohol Fermentation 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation Carboxyl (X2) to CO2 (X2) 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation Acetaldehyde produced (X2) 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation Acetaldehyde (X2) REDUCED 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation Ethanol Produced (X2) 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation Alcohol Fermentation 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 2 Pyruvate 2 Lactate Lactic acid fermentation QuickTime™ and a decompressor are needed to see this picture. Fermentation after glycolysis (no O2 Lactic acid fermentation is done by some fungi, some available) bacteria like in yogurt, and sometimes by our muscles. Fermentation after glycolysis (no O2 Lactic acid fermentation is done by some fungi, some available) bacteria like in yogurt, and sometimes by our muscles. Normally our muscles do cellular respiration like the rest of our bodies, using O2 supplied by our lungs and blood. However, under greater exertion when the oxygen supplied by the lungs and blood system can’t get there fast enough to keep up with the muscles’ needs, our muscles can switch over and do lactic acid fermentation. In the process of lactic acid fermentation, the 3-carbon pyruvic acid molecules are turned into lactic acid. Lactic Acid Fermentation 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 Pyruvate 2 Lactate Lactic acid fermentation Pyruvate (X2) reduced by NADH2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 Pyruvate 2 Lactate Lactic acid fermentation Lactate (X2) formed 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 Pyruvate 2 Lactate Lactic acid fermentation Fermentation 2 ADP + 2 P Glucose 2 ATP Glycolysis 2 NAD+ 2 NADH + 2 H+ 2 Pyruvate 2 Lactate Lactic acid fermentation QuickTime™ and a decompressor are needed to see this picture. Fermentation extension of glycolysis Anaerobic catabolism organic molecules. of •Yields only 2 ATP’s •Electrons are transferred from NADH to pyruvate (not the e- transport chain) y ruv ate as a key juncture in catabolism aerobic anaerobic Fermentation 3.5bya no oxygen