All living organisms require several compounds to continue to live. We call these compounds biomolecules. All of these biomolecules are organic, which means that they contain carbon. › Carbon has four valence electrons, which means this element forms strong covalent bonds with many other elements. All of our biomolecules are classified into four groups: › Carbohydrates › Lipids › Proteins › Nucleic Acids Each of these classes have different structures and functions. Also, our biomolecules are formed by joining many small units together to form a long chain. This process is called synthesis. Often, a water molecule is removed in the process. › When this happens, we call it dehydration synthesis. The smallest functioning unit of a biomolecule is a monomer. › “Mono-” means ONE. Put two monomers together, and you get a dimer. › Di-” means TWO. Once several monomers are put together, we get a polymer. › “Poly-” means MANY. Carbohydrates (carbs) are biomolecules used for energy and structural support. Breaking carbs down provides us with energy. Carbohydrates are made up of carbon, hydrogen and oxygen. The ratio of these elements is roughly 1carbon: 2 hydrogen :1 oxygen. Monomer: Monosaccharide Dimer: Disaccharide Polymer: Polysaccharide Carbs are primarily used to provide us with energy. All monosaccharides and dissachardies end in “-ose”. Glucose is used as a common energy source for most living organisms. There are many other types of carbs in nature: › Fructose (fruit sugar) › Lactose (milk sugar) › Sucrose (table sugar) › Ribose/Deoxyribose (important for DNA and RNA) Carbs can be bonded to each other through dehydration synthesis. › Remember, that’s when water is lost as two smaller molecules bond to form a larger molecule. When we have excess carbs, we store them as starches, which are polysaccharides. Starches are long chains of carbs. Plants also use cellulose (another polysaccharide) for structural support. Indicators are chemicals that detect the presence of a certain compound. Benedict’s solution reacts with MOST mono- and disaccharides. › Sucrose is a notable exception! If a detectable carbohydrate is present, then the indicator changes color, based on how many carbs are present. › Green → Yellow → Orange → Red This is useful for diagnosing diabetes. Iodine is used to detect starch, since it reacts readily with starch. › This reaction produces a purpleblack coloration. A ________ is made up of several smaller units, or monomers. 2. What are the two primary uses of carbohydrates? 3. Carbs can be identified because they end with the suffix ______. 4. ________ is the common energy source form almost all life on Earth. 5. Excess carbs are stored in our bodies as ________. 1. 1. 2. Use the diagram to solve the problems: Lactose is an example of what type of carb? What process joined these two carbs together? Lipids are used for four crucial purposes: › Storing energy › Waterproof barriers › Chemical messengers › Insulation Lipids are made up of carbon, hydrogen and oxygen. The ratio of these elements is roughly 1carbon: 2 hydrogen. Oxygen is present only in trace amounts. Most common lipids are composed of two different functional groups: Glycerol, an alcohol with three oxygen groups. Fatty acids, which are long hydrocarbon chains. ALL lipids repel water, due to how hydrophobic they are. This means that they do not bond to water molecules. Lipids are grouped by the number of double bonds found in the hydrocarbon chain. Saturated fats have the maximum number of hydrogen atoms possible, and as such, they have no double bonds. › They tend to be solid at room temperature. Unsaturated fats have double bonds. They do NOT have the maximum possible number of hydrogen atoms. › They tend to be liquid at room temperature. Monounsaturated fats have only ONE double bond. Polyunsaturated fats have MORE THAN ONE double bond in the hydrocarbon chain. Polyunsaturated Monounsaturated It’s important to note that fats are a specific type of lipid. Chemically, all fats are triglycerides – they have three fatty acids bonded to one glycerol molecule. Steroids are lipids with four rings bonded together. Steroids are vital as hormones, which are chemical signals used in the body. Oily and fatty foods tend to leave stains upon contact. › This is why we can use brown paper to detect fats. We can also use ethanol, which dissolves lipids. The dissolved fats are then diluted with water. Since water and lipids don’t mix, the lipids come out of solution. › This creates an emulsion – a milky, cloudy liquid. Show the ratio of carbon : hydrogen : oxygen in lipids: 2. All lipids are [hydrophilic, hydrophobic]. 3. True or false: Saturated fats have no double bonds, and the maximum number of hydrogen atoms. 4. Monounsaturated fats have __________ double bond(s). 5. _________ serve as hormones. 1. Proteins serve many vital functions in your body: › Structural support › Speeding up chemical reactions › Transport of molecules › Fighting infection › …and many more! All proteins contain carbon, hydrogen, oxygen and nitrogen. In addition, sulfur may be present as well. Monomer: Amino acid Polymer: Protein or polypeptide › A peptide is a chain of amino acids, so a polypeptide is several chains put together. ALL amino acids contain an amino or N-group. It contains nitrogen (N). ALL amino acids also contain a carboxyl or C-group. It contains carbon (C). However, amino acids also have a variable group or Rgroup. This differs from one amino acid to the next. › There are 20 standard amino acids, and thus 20 possible R-groups. Amino acids are bound together through dehydration synthesis. › The C-group of one amino acid binds to the N-group of another. › We call these bonds peptide bonds. Proteins have four phases of production: › Primary: Amino acids are bound together. › Secondary: Individual amino acids are bent and molded as needed. › Tertiary: The entire chain of amino acids is bent and molded as needed, forming a subunit. › Quaternary: Multiple completed sub-units are fitted together to make a complete protein. Protein can also function as hormones. › However, protein hormones tend to have difficulty passing the cell membrane. As such, many protein hormones have to fit a cellular receptor before they can affect the cell. The Biuret test is used to detect protein. First, protein is dissolved in water. Then, a strong base is added to the solution. Finally, 1. 2. 3. What biomolecule is being built? Amino acids are bonded together in the _________ step of production. Amino acids are held together with a _________ bond. Hydrolysis is the reverse process of dehydration synthesis. In dehydration synthesis, water is lost to create a bigger molecule. In hydrolysis, water is ADDED, and a bigger molecule is broken down into smaller pieces. › Hydrolysis = hydro and lysis. Hydro means water, and lysis means to break down. Nucleic acids are biomolecules that contain the blueprints for making proteins. Nucleic acids also transmit genetic info to the next generation. Includes: › DNA › RNA Nucleic acids contain carbon, hydrogen, oxygen, nitrogen, and phosphorus. Remember the acronym: CHONP! Monomer: Nucleotides Polymer: Nucleic Acid A nucleotide is made up of three parts: › 5-carbon sugar › Phosphate group › Nitrogenous base A nucleoside, however, is the sugar and the base WITHOUT the phosphate. The 5-carbon sugar is deoxyribose, in the case of DNA. However, it is ribose in the case of RNA. › This is how those molecules got their name! The fifth carbon of the sugar is bonded to a phosphate group. Thus, we say that this is the 5’ end. The third carbon of the sugar is bonded to an OH group. This is called is the 3’ end. As stated earlier, nucleic acids are the blueprints for proteins. Proteins are made from these templates. Also, DNA can be passed on from parent to child. This allows SOME characteristics to be passed down to offspring. These traits are considered hereditary. RNA can NOT be passed down to offspring, however! The monomer of a nucleic acid is a ____________. 2. All nucleotides contain which three components? 3. DNA carries information down from generation to generation. This information is _____________. 4. DNA and RNA contain which elements? 1.